Updated on 2024/03/29

写真a

 
NISHIDA, Nao
 
Affiliation
Affiliated organization, Waseda Institute for Advanced Study
Job title
Assistant Professor(non-tenure-track)
Degree
PhD(Agriculture) ( 2014.03 Kyoto University )
Mail Address
メールアドレス

Research Experience

  • 2022.04
    -
    Now

    Waseda University   Institue for Advanced Study   Assistant Professor

  • 2021.09
    -
    2022.03

    Tokyo Medical University   Institute of Medical Science   Assistant Professor

  • 2017.04
    -
    2021.08

    Fred Hutchinson Cancer Center   Human Biology Division   Postdoctoral Fellow

  • 2017.04
    -
    2019.03

    Japan Society for the Promotion of Science   Overseas Research Fellow

  • 2014.04
    -
    2017.03

    Japan Society for the Promotion of Science   Research Fellow (PD)

  • 2014.04
    -
    2017.03

    National Cancer Center   Research Institute

  • 2012.04
    -
    2014.03

    Japan Society for the Promotion of Science   Research Fellow (DC2)

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Education Background

  • 2011.04
    -
    2014.03

    Kyoto University   Graduate School of Agriculture   Division of Applied Life Sciences  

    Doctoral course

  • 2009.04
    -
    2011.03

    Kyoto University   Graduate School of Agriculture   Division of Applied Life Sciences  

    Master's course

  • 2005.04
    -
    2009.03

    Kyoto University   Faculty of Agriculture   Division of Applied Life Sciences  

Committee Memberships

  • 2022.04
    -
    Now

    Japanese Society for Extracellular Vesicles  Director

Research Areas

  • Cell biology   Cell-cell interactions, extracellular vesicles, exosomes / Tumor biology   Tumor microenvironment

Research Interests

  • Tumor microenvironment

  • Cell-cell interaction

  • Organotypic culture

  • Extracellular vesicles

  • Exosome

  • Tumor-associated macrophage

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Awards

  • 卓越研究員候補

    2021   日本学術振興会  

  • ISEV2017 Junior Member Scholarship

    2017.05   International Society for Extracellular Vesicles  

  • 若手優秀発表賞

    2015.12   第38回日本分子生物学会年会・第88回日本生化学会大会 合同大会  

 

Papers

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Books and Other Publications

  • 医療を変えるエクソソーム : 生体機能から疾患メカニズム、臨床応用まで

    落谷, 孝広, 吉岡, 祐亮( Part: Contributor, 26章 エクソソームを応用した治療法の開発)

    化学同人  2018.08 ISBN: 9784759819786

  • 直径100nmのメッセンジャーエクソソームは診断・治療に革命をもたらすか? : 特集

    吉岡, 祐亮, 落谷, 孝広( Part: Contributor, 6. エクソソームが築く次世代の医療)

    羊土社  2016.06 ISBN: 9784758101523

Research Projects

  • Mechanisms of inducible secretion of cancer extracellular vesicles upon cell recognition and contribution to cancer malignancy

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research

    Project Year :

    2023.04
    -
    2026.03
     

  • がん組織内における細胞外小胞のヘテロな分布の検出

    公益財団法人 上原記念生命科学財団  上原記念生命科学財団研究奨励金

    Project Year :

    2024.04
    -
    2025.03
     

  • がん由来細胞外小胞を取り込む細胞の組織内分布の解析

    公益財団法人 三菱財団  三菱財団自然科学研究助成

    Project Year :

    2023.10
    -
    2024.09
     

Misc

  • 環境によって良くも悪くもふるまうがん細胞

    西田 奈央

    生物工学会誌   101 ( 2 ) 86  2023.02

    Authorship:Lead author

    DOI

  • Composition and Biological Activities of Exosomal Lipids Bilayers

    Nao NISHIDA-AOKI

    Oleoscience   21 ( 2 ) 69 - 75  2021.02

    Authorship:Lead author

    DOI

  • Multilateral strategies utilizing exosomes for cancer therapy

    Nishida-Aoki, N., Ochiya, T.

    Japanese Journal of Cancer and Chemotherapy   44 ( 5 ) 367 - 372  2017.05

    Authorship:Lead author

  • The mechanism of organic-solvent tolerance in yeast Saccharomyces cerevisiae triggered by a mutated transcription factor

    Kouichi Kuroda, Nao Nishida, Mitsuyoshi Ueda

    NEW BIOTECHNOLOGY   33   S59 - S59  2016.07

    Research paper, summary (international conference)  

    DOI

  • Variety of biological phenomena brought by exosomes

    Nao Nishida-Aoki, Takahiro Ochiya

      16 ( 2 ) 107 - 116  2015.06

    Authorship:Lead author

  • Lipid Bilayer Exosome–mediated Disease Diagnosis and Treatment Utilizing Exosomes

    Nao Nishida, Takahiro Ochiya

    membrane   40 ( 5 ) 235 - 241  2015

    Authorship:Lead author

    DOI

  • Organic solvent-activated signaling pathways via cell surface sensors and transcription factors

    Kouichi Kuroda, Nao Nishida, Mitsuyoshi Ueda

    FASEB JOURNAL   28 ( 1 )  2014.04

    Research paper, summary (international conference)  

  • Relationships between cancer cells and normal cells by transfer of miRNA via extracellular vesicles

    Nao Nishida-Aoki, Takahiro Ochiya

    Antisense   18 ( 2 ) 3 - 12  2014

    Authorship:Lead author

  • Effects of recognition sequence variations on transcription regulation of multidrug resistance regulator Pdr1p in yeast

    Nao Nishida, Kouichi Kuroda, Mitsuyoshi Ueda

    FASEB JOURNAL   27  2013.04

    Research paper, summary (international conference)  

  • ABC transporters and cell wall proteins involved in yeast organic solvent tolerance

    Nao Nishida, Naoki Ozato, Jing Dongyu, Kouichi Kuroda, Mitsuyoshi Ueda

    NEW BIOTECHNOLOGY   29   S104 - S104  2012.09

    Research paper, summary (international conference)  

    DOI

  • Functional analysis of Pdr1p in multidrug resistance and organic-solvent tolerance in yeast

    Nao Nishida, Naoki Ozato, Mitsuaki Sanada, Kouichi Kuroda, Mitsuyoshi Ueda

    FASEB JOURNAL   25  2011.04

    Research paper, summary (international conference)  

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Syllabus

 

Sub-affiliation

  • Faculty of Science and Engineering   School of Advanced Science and Engineering

Internal Special Research Projects

  • がん由来細胞外小胞の組織形成や維持における役割の解明

    2022  

     View Summary

    本課題では、がん組織内で活発に交換されるエクソソームを含む細胞外小胞(Extracellular vesicles,EV)が、がん組織の形成や機能維持に果たす役割を明らかにする目的で研究を行った。がん細胞株と正常細胞株を用いた共培養系を用いて、当初持っていた仮説を実証するデータを得ることができ、さらに新たな仮説を得た。この予備実験のデータを元に科研費課題を提案し資金を獲得することができた。また、今後研究を進める上で必要となるEVの分泌阻害剤の、最適な種類と添加条件の検討を行った。本課題により、他の研究課題と相補的な位置付けで、がん組織内のEVを介した細胞間相互作用を理解する上で役立つ最初のデータを得ることができた。