中村 宣博 (ナカムラ ノブヒロ)

写真a

所属

スポーツ科学学術院 スポーツ科学部

職名

助教

学歴 【 表示 / 非表示

  • 2016年04月
    -
    2019年03月

    早稲田大学大学院   大学院スポーツ科学研究科  

学位 【 表示 / 非表示

  • 早稲田大学   博士(スポーツ科学)

経歴 【 表示 / 非表示

  • 2021年04月
    -
    継続中

    横浜商科大学   商学部   非常勤講師

  • 2021年04月
    -
    継続中

    早稲田大学   スポーツ科学学術院   助教

  • 2019年04月
    -
    2021年03月

    横浜商科大学   商学部 経営情報学科   専任講師

所属学協会 【 表示 / 非表示

  •  
     
     

    European College of Sport Science

  •  
     
     

    日本体力医学会

 

研究分野 【 表示 / 非表示

  • 医療薬学

  • 生理学

  • 栄養学、健康科学

研究キーワード 【 表示 / 非表示

  • 生理学

  • 運動生理学

  • スポーツ生理学

  • トレーニング

  • 動脈硬化

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論文 【 表示 / 非表示

  • The Effects of Beverage Intake after Exhaustive Exercise on Organ Damage, Inflammation and Oxidative Stress in Healthy Males.

    Takaki Tominaga, Tsukasa Ikemura, Koichi Yada, Kazue Kanda, Kaoru Sugama, Sihui Ma, Wonjun Choi, Mayu Araya, Jiapeng Huang, Nobuhiro Nakamura, Katsuhiko Suzuki

    Antioxidants (Basel, Switzerland)   10 ( 6 )  2021年05月  [国際誌]

     概要を見る

    Strenuous exercise induces organ damage, inflammation and oxidative stress. To prevent exercise-induced organ damage, inflammation and oxidative stress, rehydrating may be an effective strategy. In the present study, we aimed to examine whether beverage intake after exhaustive exercise to recover from dehydration prevents such disorders. Thirteen male volunteers performed incremental cycling exercise until exhaustion. Immediately after exercise, the subjects drank an electrolyte containing water (rehydrate trial: REH) or did not drink any beverage (control trial: CON). Blood samples were collected before (Pre), immediately (Post), 1 h and 2 h after exercise. Urine samples were also collected before (Pre) and 2 h after exercise. We measured biomarkers of organ damage, inflammation and oxidative stress in blood and urine. Biomarkers of muscle, renal and intestinal damage and inflammation increased in the blood and urine after exercise. However, changes in biomarkers of organ damage and inflammation did not differ between trials (p > 0.05). The biomarker of oxidative stress, thiobarbituric acid reactive substances (TBARS), in plasma, showed different changes between trials (p = 0.027). One hour after exercise, plasma TBARS concentration in REH had a higher trend than that in CON (p = 0.052), but there were no significant differences between Pre and the other time points in each trial. These results suggest that beverage intake after exercise does not attenuate exercise-induced organ damage, inflammation or oxidative stress in healthy males. However, rehydration restores exercise-induced oxidative stress more quickly.

    DOI PubMed

  • Determinants of Resting Oxidative Stress in Middle-Aged and Elderly Men and Women: WASEDA'S Health Study.

    Takuji Kawamura, Kumpei Tanisawa, Ryoko Kawakami, Chiyoko Usui, Tomoko Ito, Hiroki Tabata, Nobuhiro Nakamura, Sayaka Kurosawa, Wonjun Choi, Sihui Ma, Zsolt Radak, Susumu S Sawada, Katsuhiko Suzuki, Kaori Ishii, Shizuo Sakamoto, Koichiro Oka, Mitsuru Higuchi, Isao Muraoka

    Oxidative medicine and cellular longevity   2021   5566880 - 5566880  2021年  [国際誌]

     概要を見る

    Previous studies have not investigated the determinants of resting oxidative stress, including physical fitness, as it relates to redox regulation. The present study therefore was aimed at identifying lifestyle and biological factors that determine resting oxidative stress, including objectively measured physical fitness. In 873 middle-aged and elderly men and women, age and anthropometric parameters, lifestyle-related parameters, medication and supplementation status, physical fitness, biochemical parameters, and nutritional intake status, as well as three plasma oxidative stress markers: protein carbonyl (PC), F2-isoprostane (F2-IsoP), and thiobarbituric acid reactive substances (TBARS), were surveyed and measured. The determinants of PC, F2-IsoP, and TBARS in all participants were investigated using stepwise multiple regression analysis. In PC, age (β = -0.11, P = 0.002), leg extension power (β = -0.12, P = 0.008), BMI (β = 0.12, P = 0.004), and HDL-C (β = 0.08, P = 0.040) were included in the regression model (adjusted R 2 = 0.018). In the F2-IsoP, smoking status (β = 0.07, P = 0.060), BMI (β = 0.07, P = 0.054), and HbA1c (β = -0.06, P = 0.089) were included in the regression model (adjusted R 2 = 0.006). In TBARS, glucose (β = 0.18, P < 0.001), CRF (β = 0.16, P < 0.001), age (β = 0.15, P < 0.001), TG (β = 0.11, P = 0.001), antioxidant supplementation (β = 0.10, P = 0.002), and HbA1c (β = -0.13, P = 0.004) were included in the regression model (adjusted R 2 = 0.071). In conclusion, the present study showed that age, anthropometric index, lifestyle-related parameters, medication and supplementation status, objectively measured physical fitness, biochemical parameters, and nutritional intake status explain less than 10% of oxidative stress at rest.

    DOI PubMed

  • Acute effect of increased arterial stiffness by high-intensity resistance exercise on cerebral blood flow.

    Nakamura N, Ikemura T, Muraoka I

    Gazzetta Medica Italiana - Archivio per le Scienze Mediche (In press)   178 ( 4 ) 195 - 202  2019年04月  [査読有り]

  • Effect of accommodating elastic bands on mechanical power output during back squats.

    Kubo T, Hirayama K, Nakamura N, Higuchi M

    Sports (Basel)   6 ( 4 )  2018年11月  [査読有り]  [国際誌]

     概要を見る

    The aim of this study was to investigate whether accommodating elastic bands with barbell back squats (BSQ) increase muscular force during the deceleration subphase. Ten healthy men (mean ± standard deviation: Age: 23 ± 2 years; height: 170.5 ± 3.7 cm; mass: 66.7 ± 5.4 kg; and BSQ one repetition maximum (RM): 105 ± 23.1 kg; BSQ 1RM/body mass: 1.6 ± 0.3) were recruited for this study. The subjects performed band-resisted parallel BSQ (accommodating elastic bands each sides of barbell) with five band conditions in random order. The duration of the deceleration subphase, mean mechanical power, and the force and velocity during the acceleration and deceleration subphases were calculated. BSQ with elastic bands elicited greater mechanical power output, velocity, and force during the deceleration subphase, in contrast to that elicited with traditional free weight (p < 0.05). BSQ with elastic bands also elicited greater mechanical power output and velocity during the acceleration subphase. However, the force output during the acceleration subphase using an elastic band was lesser than that using a traditional free weight (p < 0.05). This study suggests that BSQ with elastic band elicit greater power output during the acceleration and deceleration subphases.

    DOI PubMed

  • Influence of different loads on force-time characteristics during back squats

    Kubo T, Hirayama K, Nakamura N, Higuchi M

    Journal of Sports Science and Medicine   17 ( 4 ) 617 - 622  2018年11月  [査読有り]  [国際誌]

     概要を見る

    The deceleration sub-phase during the back squat (BSQ) makes it difficult to stimulate the muscles throughout the full range of motion, and it has only been reported for one load during BSQ. The purpose of this study was to investigate whether a deceleration sub-phase occurs during BSQ with different loads and to assess the influence of load on the deceleration sub-phase duration and negative impulse during the deceleration sub-phase. Sixteen healthy men (mean ± standard deviation: age: 25 ± 3 years; height: 1.73 ± 0.07 m; mass: 83.2 ± 16.1 kg; BSQ one repetition maximum (1RM): 163.8 ± 36.6 kg; BSQ 1RM/body weight: 2.0 ± 0.4) who had performed resistance training for at least 1 year were recruited for this study. The subjects performed parallel BSQ with 0%, 12%, 27%, 42%, 56%, 71%, and 85% of each 1RM on a force plate in a random order. The deceleration sub-phase duration and negative impulse during the deceleration sub-phase were calculated from force-time data. The absolute durations of the deceleration sub-phase were not significantly different according to load except for 27% 1RM and 85% 1RM (p = 0.01). However, as the load increased from 12 to 85% 1RM, the relative duration of the deceleration sub-phase decreased (p < 0.05). The negative impulse during the deceleration sub-phase also increased from 0 to 42% 1RM (p < 0.05). A deceleration sub-phase occurs regardless of the load (0%-85% 1RM), and a large portion of the deceleration sub-phase occupied the concentric phase, with low-moderate loads, and a large amount of negative impulse occurred during the short deceleration sub-phase with a high load.

    PubMed

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Misc 【 表示 / 非表示

受賞 【 表示 / 非表示

  • 濱野吉生記念褒賞

    2019年03月   早稲田大学スポーツ科学研究科  

    受賞者: 中村 宣博

共同研究・競争的資金等の研究課題 【 表示 / 非表示

  • 筋力トレーニングに伴う動脈硬化は動脈圧受容器の感受性を鈍化させてしまうのか?

    研究活動スタート支援

    研究期間:

    2019年08月
    -
    2021年03月
     

    中村 宣博

     概要を見る

    動脈圧受容器反射は短期的な血圧変動に対して血圧の恒常性を維持する最も重要な調節機構である。この反射の感受性は加齢や高血圧によって鈍化することが報告されている。また、動脈圧受容器反射感受性の鈍化が重篤な不整脈のリスク増大につながることや急性心臓死の前兆となることが報告されている。動脈圧受容器反射は大動脈洞および頸動脈洞が動脈の伸展を感知し、その程度に応じて血圧を調節しているため、大動脈や頸動脈といった動脈の硬化度が動脈圧受容器反射の感受性の低下と関連することが報告されている。
    筋力トレーニングは日常生活動作(ADL)の改善ひいては健康寿命の延伸に寄与することが期待されており、広く推奨されている。一方、筋力トレーニングは動脈硬化を促進させることが報告されている。また、いくつかの研究では、習慣的に筋力トレーニングを実施している者(鍛錬者)は同年代の非鍛錬者よりも動脈硬化度が高いことが示されている。さらに、メタ解析においても同様の結果が得られている。しかし、この動脈硬化がどのような弊害を有しているかについてほとんど検討されていないのが現状である。
    先行研究では、習慣的な運動による動脈の硬化度の変化が動脈圧受容器反射の感受性を変化させることが示唆されている。以上のことから、筋力トレーニングに伴う中心動脈スティフネスの増加およびコンプライアンスの低下は動脈圧受容器反射の感受性を鈍化させる可能性があると思われる。そこで、本研究課題は筋力トレーニングに伴う動脈硬化が動脈圧受容器反射の感受性に及ぼす影響を検討することとした。

講演・口頭発表等 【 表示 / 非表示

  • Parasympathetic nervous regulation and prevalence of lifestyle-related diseases in Japanese: WASEDA'S Health Study

    Masayuki Konishi, Susumu S. Sawada, Ryoko Kawakami, Kumpei Tanisawa, Hiroki Tabata, Nobuhiro Nakamura, Hyeon-Ki Kim, Tomoko Ito, Mitsuru Higuchi, Katsuhiko Suzuki, Suguru Torii, I-Min Lee F, Steven N. Blair, Koichiro Oka, Shizuo Sakamoto

    66th Annual Meeting of the American College of Sports Medicine  

    発表年月: 2019年05月

  • Cardiorespiratory fitness and prevalence of lifestyle-related diseases in Japanese men and womenWASEDA’S Health Study

    Susumu S. Sawada, Ryoko Kawakami, Kumpei Tanisawa, Hiroki Tabata, Nobuhiro Nakamura, Hyeon-Ki Kim, Masayuki Konishi, Tomoko Ito, Chiyoko Usui, Taishi Midorikawa, Mitsuru Higuchi, Katsuhiko Suzuki, Suguru Torii, I-Min Lee, Steven N. Blair, Isao Muraoka, Kaori Ishii, Koichiro Oka, Shizuo Sakamoto

    66th Annual Meeting of the American College of Sports Medicine  

    発表年月: 2019年05月

  • 中高齢男女における潜水徐脈および運動後心拍回復と生活習慣病有病率の関係:WASEDA'S Health Study

    小西 真幸, 澤田 享, 川上 諒子, 谷澤 薫平, 田端 宏樹, 中村 宣博, 金 鉉基, 伊藤 智子, 樋口 満, 鈴木 克彦, 鳥居 俊, 村岡 功, 石井 香織, 岡 浩一朗, 坂本 静男

    第6回介護予防・健康 づくり学会大会  

    発表年月: 2018年11月

  • 日本人中高齢者における全身持久力と生活習慣病有病率の関係-WASEDA'S Health Study-

    澤田 享, 川上 諒子, 谷澤 薫平, 田端 宏樹, 中村 宣博, 金 鉉基, 小西 真幸, 伊藤 智子, 薄井 澄誉子, 緑川 泰史, 樋口 満, 鈴木 克 彦, 鳥居 俊, 村岡 功, 石井 香織, 岡 浩一朗, 坂本 静男

    第6回介護予防・健康 づくり学会大会  

    発表年月: 2018年11月

  • 腸内水素ガス産生乳飲料の摂取が高強度運動後の酸化ストレス応答に及ぼす影響

    枝 伸彦, 中村 宣博, 曽根 良太, 松本 光晴, 赤間 高雄

    第73回日 本体力医学会大会  

    発表年月: 2018年09月

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