Concurrent Post 【 display / non-display 】

Concurrent Post 【 display / non-display 】

• Affiliated organization   Global Education Center

Education 【 display / non-display 】

Education 【 display / non-display 】

• 2012.04

  -

  2015.03

  Waseda University  

• 2010.04

  -

  2012.03

  Waseda University  

• 2006.04

  -

  2010.03

  Waseda University   School of Sport Sciences  

Degree 【 display / non-display 】

Degree 【 display / non-display 】

• 早稲田大学   博士（スポーツ科学）

Research Experience 【 display / non-display 】

Research Experience 【 display / non-display 】

• 2019.04

  -

  Now

  Waseda University   Faculty of Sport Sciences

• 2018.07

  -

  2019.03

  University of Brighton   Visiting Researcher,

• 2016.04

  -

  2019.03

  医薬基盤・健康・栄養研究所   身体活動研究部   流動研究員

• 2015.04

  -

  2019.03

  日本学術振興会   特別研究員PD

• 2014.04

  -

  2015.03

  日本学術振興会   特別研究員DC2

Professional Memberships 【 display / non-display 】

Professional Memberships 【 display / non-display 】

• 　

  　

  　

  American College of Sports Medicine

• 　

  　

  　

  JAPAN SOCIETY FOR BIOMEDICAL GERONTOLOGY

• 　

  　

  　

  THE JAPANESE SOCIETY OF PHYSICAL FITNESS AND SPORTS MEDICINE

Research Areas 【 display / non-display 】

Research Areas 【 display / non-display 】

• Sports sciences

• Nutrition science and health science

Research Interests 【 display / non-display 】

Research Interests 【 display / non-display 】

• 個人差

• 運動処方

• 老化

• 生活習慣病

• 遺伝子多型

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Papers 【 display / non-display 】

Papers 【 display / non-display 】

• Establishing a Global Standard for Wearable Devices in Sport and Exercise Medicine: Perspectives from Academic and Industry Stakeholders.

  Garrett I Ash, Matthew Stults-Kolehmainen, Michael A Busa, Allison E Gaffey, Konstantinos Angeloudis, Borja Muniz-Pardos, Robert Gregory, Robert A Huggins, Nancy S Redeker, Stuart A Weinzimer, Lauren A Grieco, Kate Lyden, Esmeralda Megally, Ioannis Vogiatzis, LaurieAnn Scher, Xinxin Zhu, Julien S Baker, Cynthia Brandt, Michael S Businelle, Lisa M Fucito, Stephanie Griggs, Robert Jarrin, Bobak J Mortazavi, Temiloluwa Prioleau, Walter Roberts, Elias K Spanakis, Laura M Nally, Andre Debruyne, Norbert Bachl, Fabio Pigozzi, Farzin Halabchi, Dimakatso A Ramagole, Dina C Janse van Rensburg, Bernd Wolfarth, Chiara Fossati, Sandra Rozenstoka, Kumpei Tanisawa, Mats Börjesson, José Antonio Casajus, Alex Gonzalez-Aguero, Irina Zelenkova, Jeroen Swart, Gamze Gursoy, William Meyerson, Jason Liu, Dov Greenbaum, Yannis P Pitsiladis, Mark B Gerstein

  Sports medicine (Auckland, N.Z.)   51 ( 11 ) 2237 - 2250  2021.11  [Refereed]  [International journal]

  　View Summary

  Millions of consumer sport and fitness wearables (CSFWs) are used worldwide, and millions of datapoints are generated by each device. Moreover, these numbers are rapidly growing, and they contain a heterogeneity of devices, data types, and contexts for data collection. Companies and consumers would benefit from guiding standards on device quality and data formats. To address this growing need, we convened a virtual panel of industry and academic stakeholders, and this manuscript summarizes the outcomes of the discussion. Our objectives were to identify (1) key facilitators of and barriers to participation by CSFW manufacturers in guiding standards and (2) stakeholder priorities. The venues were the Yale Center for Biomedical Data Science Digital Health Monthly Seminar Series (62 participants) and the New England Chapter of the American College of Sports Medicine Annual Meeting (59 participants). In the discussion, stakeholders outlined both facilitators of (e.g., commercial return on investment in device quality, lucrative research partnerships, and transparent and multilevel evaluation of device quality) and barriers (e.g., competitive advantage conflict, lack of flexibility in previously developed devices) to participation in guiding standards. There was general agreement to adopt Keadle et al.'s standard pathway for testing devices (i.e., benchtop, laboratory, field-based, implementation) without consensus on the prioritization of these steps. Overall, there was enthusiasm not to add prescriptive or regulatory steps, but instead create a networking hub that connects companies to consumers and researchers for flexible guidance navigating the heterogeneity, multi-tiered development, dynamicity, and nebulousness of the CSFW field.

  DOI PubMed

• Effect of a 1-year intervention comprising brief counselling sessions and low-dose physical activity recommendations in Japanese adults, and retention of the effect at 2 years: a randomized trial.

  Julien Tripette, Yuko Gando, Haruka Murakami, Ryoko Kawakami, Kumpei Tanisawa, Harumi Ohno, Kana Konishi, Michiya Tanimoto, Noriko Tanaka, Hiroshi Kawano, Kenta Yamamoto, Akie Morishita, Motoyuki Iemitsu, Kiyoshi Sanada, Nobuyuki Miyatake, Motohiko Miyachi

  BMC sports science, medicine & rehabilitation   13 ( 1 ) 133 - 133  2021.10  [Refereed]  [International journal]

  　View Summary

  BACKGROUND: In an effort to increase people's adherence to active lifestyles, contemporary physical activity (PA) guidelines now include low-dose PA. METHODS: PA was evaluated in 583 participants of the Nutritional and Physical Activity Intervention Study (NEXIS) cohort (30-65 years old); 349 inactive participants (MVPA, 2.7 ± 1.0 MET-h/day) were randomly assigned to the intervention or control groups, and 235 active participants participated in follow-up visits. The intervention aimed to increase MVPA and comprised five brief counseling sessions over 1 year. The 1-year target for the participant was increasing their step-count to 10,000 steps/d or +3000 steps/d, relative to the baseline score. The counseling sessions were designed to stimulate progressive changes in physical behaviors by recommendations promoting small and/or light-intensity bouts of PA. PA was measured at baseline, the end of the intervention, and 1 year after the intervention ended. Additionally, several nutrition, health, and fitness parameters were measured. RESULTS: Participants in the intervention group significantly increased their step-count from 8415 ± 1924 at baseline to 9493 ± 2575 at the end of the 1-year period. During the same period, MVPA significantly increased by 0.9 MET-h. The daily time spent in ≥ 3, ≥ 4 and ≥ 5 MET activities increased by 11, 6, and 3 min, respectively. This increase in PA remained observable 1 year after intervention concluded. The active group maintained higher physical activity levels throughout the two years. The intervention group showed smaller energy intakes at the end of the 2-year period. Significant correlations were noted between the 1-year change in MVPA and the change in resting heart rate (r =  - 0.22), and between the 2-year change in MVPA and the change in waist circumference (r =  - 0.08) and peak oxygen consumption capacity (r = 0.23) in the intervention group only. CONCLUSIONS: A prolonged and progressive PA intervention promoting small bouts of light-to-moderate PA may be used in healthy, not-optimally-active people to increase PA beyond the strict period of the intervention. Further studies are necessary to understand whether low-dose PA messages can be effective in initiating a progressive increase toward larger amounts of PA. TRIAL REGISTRATION: Clinical Trials.gov, NCT00926744, retrospectively registered.

  DOI PubMed

• Development and validation of a simple anthropometric equation to predict appendicular skeletal muscle mass.

  Ryoko Kawakami, Motohiko Miyachi, Kumpei Tanisawa, Tomoko Ito, Chiyoko Usui, Taishi Midorikawa, Suguru Torii, Kaori Ishii, Katsuhiko Suzuki, Shizuo Sakamoto, Mitsuru Higuchi, Isao Muraoka, Koichiro Oka

  Clinical nutrition (Edinburgh, Scotland)   40 ( 11 ) 5523 - 5530  2021.09  [Refereed]  [International journal]

  　View Summary

  BACKGROUND & AIMS: A limited number of studies have developed simple anthropometric equations that can be implemented for predicting muscle mass in the local community. Several studies have suggested calf circumference as a simple and accurate surrogate maker for muscle mass. We aimed to develop and cross-validate a simple anthropometric equation, which incorporates calf circumference, to predict appendicular skeletal muscle mass (ASM) using dual-energy X-ray absorptiometry (DXA). Furthermore, we conducted a comparative validity assessment of our equation with bioelectrical impedance analysis (BIA) and two previously reported equations using similar variables. METHODS: ASM measurements were recorded for 1262 participants (837 men, 425 women) aged 40 years or older. Participants were randomly divided into the development or validation group. Stepwise multiple linear regression was applied to develop the DXA-measured ASM prediction equation. Parameters including age, sex, height, weight, waist circumference, and calf circumference were incorporated as predictor variables. Total error was calculated as the square root of the sum of the square of the difference between DXA-measured and predicted ASMs divided by the total number of individuals. RESULTS: The most optimal ASM prediction equation developed was: ASM (kg) = 2.955 × sex (men = 1, women = 0) + 0.255 × weight (kg) - 0.130 × waist circumference (cm) + 0.308 × calf circumference (cm) + 0.081 × height (cm) - 11.897 (adjusted R2 = 0.94, standard error of the estimate = 1.2 kg). Our equation had smaller total error and higher intraclass correlation coefficient (ICC) values than those for BIA and two previously reported equations, for both men and women (men, total error = 1.2 kg, ICC = 0.91; women, total error = 1.1 kg, ICC = 0.80). The correlation between DXA-measured ASM and predicted ASM by the present equation was not significantly different from the correlation between DXA-measured ASM and BIA-measured ASM. CONCLUSIONS: The equation developed in this study can predict ASM more accurately as compared to equations where calf circumference is used as the sole variable and previously reported equations; it holds potential as a reliable and an effective substitute for estimating ASM.

  DOI PubMed

• Combined association of cardiorespiratory fitness and muscle mass with the prevalence of diabetes mellitus: WASEDA’S Health Study

  Ryoko Kawakami, Dong Wang, Susumu S. Sawada, Kumpei Tanisawa, Hiroki Tabata, Tomoko Ito, Chiyoko Usui, Kaori Ishii, Suguru Torii, Mitsuru Higuchi, Katsuhiko Suzuki, Shizuo Sakamoto, Koichiro Oka

  J Phys Fitness Sports Med   in press  2021.09  [Refereed]

• Association between alcohol dietary pattern and prevalence of dyslipidaemia: WASEDA'S Health Study.

  Kumpei Tanisawa, Tomoko Ito, Ryoko Kawakami, Chiyoko Usui, Takuji Kawamura, Katsuhiko Suzuki, Shizuo Sakamoto, Kaori Ishii, Isao Muraoka, Koichiro Oka, Mitsuru Higuchi

  The British journal of nutrition     1 - 31  2021.07  [Refereed]  [International journal]

  Authorship：Lead author, Corresponding author

  　View Summary

  The association between a dietary pattern characterised by high alcohol intake and dyslipidaemia has not been fully investigated. Therefore, the present study aimed to investigate the association between alcohol dietary patterns and the prevalence of dyslipidaemia and its components. This cross-sectional study enrolled 2,171 men and women aged ≥40 years who were alumni of a Japanese university. To identify dietary patterns, a principal component analysis was performed based on the energy-adjusted food intake estimated by a brief-type self-administered diet history questionnaire. Three dietary patterns were identified, the second of which was named the alcohol dietary pattern and was characterised by a high intake of alcoholic beverages, liver, chicken, and fish. This alcohol dietary pattern was associated with reduced low-density lipoprotein cholesterol (LDL-C) levels. The fully adjusted odds ratios (95% confidence intervals) of high LDL-C for the lowest through highest quartile of alcohol dietary pattern score were 1.00 (reference), 0.83 (0.64-1.08), 0.84 (0.64-1.10), and 0.68 (0.49- 0.94), respectively. Subgroup analysis showed that the alcohol dietary pattern was inversely associated with the prevalence of dyslipidaemia in women, whereas it was positively associated with high triglyceride levels in men. In conclusion, the alcohol dietary pattern, characterised by a high intake of alcoholic beverages, liver, chicken, and fish, was associated with the prevalence of dyslipidaemia and its components. This finding provides useful information for the prevention and treatment of dyslipidaemia by modifying the diet.

  DOI PubMed

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Misc 【 display / non-display 】

Misc 【 display / non-display 】

• Cardiorespiratory Fitness And Muscle Strength With The Prevalence Of Diabetes: WASEDA'S Health Study

  Dong Wang, Susumu S. Sawada, Hiroki Tabata, Kumpei Tanisawa, Ryoko Kawakami, Kaori Ishii, Katsuhiko Suzuki, Mitsuru Higuchi, Koichiro Oka, Shizuo Sakamoto

  MEDICINE AND SCIENCE IN SPORTS AND EXERCISE   52 ( 17 ) 548 - 548  2020.07

  Research paper, summary (international conference)  

• Parasympathetic Nervous Regulation and Prevalence of Lifestyle-related Diseases In Japanese: Waseda's Health Study

  Masayuki Konishi, Susumu S. Sawada, Ryoko Kawakami, Kumpei Tanisawa, Hiroki Tabata, Nobuhiro Nakamura, Hyeon-Ki Kim, Tomoko Ito, Mitsuru Higuchi, Katsuhiko Suzuki, Suguru Torii, I-Min Lee, Steven N. Blair, Koichiro Oka, Shizuo Sakamoto

  MEDICINE AND SCIENCE IN SPORTS AND EXERCISE   51 ( 6 ) 216 - 216  2019.06

  Research paper, summary (international conference)  

  DOI

• Cardiorespiratory Fitness is Associated With Age-Related Carotid Enlargement: A 5-Year Longitudinal Study

  Yuko Gando, Haruka Murakami, Ryoko Kawakami, Harumi Ohno, Kumpei Tanisawa, Kana Konishi, Susumu S. Sawada, Nobuyuki Miyatake, Motohiko Miyachi

  CIRCULATION   136  2017.11

  Research paper, summary (international conference)  

  　View Summary

  0

• 持久性運動開始直前の糖質摂取による運動誘発性低血糖(インスリン・ショック)の発生を規定する要因の解明

  谷澤 薫平, 近藤 早希, 伊藤 智子, 孫 暁敏, 鈴木 克彦

  デサントスポーツ科学   38   80 - 88  2017.05

  　View Summary

  本研究は、持久性運動開始3時間前の食事摂取の有無が、運動開始直前の糖質摂取による低血糖の発生に及ぼす影響を明らかにすることと、運動開始直前の糖質摂取による低血糖を規定する要因を明らかにすることを目的として行った。16名の若年日本人男性を対象として、運動開始3時間前に朝食を摂取する条件と、一晩絶食の条件において、150gのグルコースを摂取した30分後に、最大酸素摂取量の75%の強度で60分の自転車運動を行った。両条件において、運動開始15分後における血糖値の平均値は低血糖の基準である70mg/dLを下回らなかったが、朝食摂取条件では7名、絶食条件では5名において低血糖が起こった。朝食摂取条件において、低血糖が起こった者は、正常血糖の者と比較して最大酸素摂取量が有意に高く、絶食条件においては、運動開始直前のインスリン濃度とインスリン分泌指標が高かった。以上の結果より、若年日本人男性において、摂食状況に関わらず、運動開始直前の糖質摂取により低血糖が起こる者がいることが明らかになった。また、運動3時間前に食事を摂取した状態においては最大酸素摂取量が、一晩絶食の状態においては、インスリン初期分泌反応が高い者において、低血糖が起こりやすい可能性が示唆された。(著者抄録)

• 元気高齢者の栄養

  樋口 満, 伊藤 智子, 谷澤 薫平, 孫 暁敏

  介護福祉・健康づくり   1 ( 2 ) 110 - 113  2014.12

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Awards 【 display / non-display 】

Awards 【 display / non-display 】

• 論文賞

  2015.11   ネスレ栄養科学会議  

  Winner： 谷澤 薫平

• 濱野吉生記念褒賞

  2015.03   早稲田大学スポーツ科学研究科  

  Winner： 谷澤 薫平

• 小野梓記念学術賞

  2015.03   早稲田大学  

  Winner： 谷澤 薫平

• 奨励賞

  2013.06   日本基礎老化学会  

  Winner： 谷澤 薫平

• 若手研究奨励賞

  2012.07   SAM研究協議会  

  Winner： 谷澤 薫平

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Research Projects 【 display / non-display 】

Research Projects 【 display / non-display 】

• Assessing causal relationship of skeletal muscle- and fitness-related myokines with cardiometabolic risk factors

  Grant-in-Aid for Scientific Research (B)

  Project Year :

  2019.04

  -

  2022.03

   

• Genetic epidemiological study for developing preventive methods of hyper-LDL cholesterolemia in non-obese individuals

  Grant-in-Aid for Young Scientists (B)

  Project Year :

  2017.04

  -

  2019.03

   

• 日本人における２型糖尿病の遺伝的背景・成因を考慮した個別化予防システムの構築

  特別研究員奨励費

  Project Year :

  2016.04

  -

  2019.03

   

  谷澤 薫平

  　View Summary

  本研究の目的は、個々の2型糖尿病の発症パターンを早期に予測するため、2型糖尿病の主要な成因であるインスリン分泌能低下とインスリン抵抗性を予測するための遺伝的リスクスコア(Genetic risk score: GRS)を構築し、GRSによる2型糖尿病発症パターンの分類を行うことと、これらGRSが2型糖尿病発症に及ぼす影響は、どのような生活習慣・身体特性を有する者において弱まるかを明らかにすることである。本年度は、2型糖尿病の既往歴のない中高齢者において、昨年度までに構築したインスリン分泌能低下を予測する遺伝的リスクスコア（insulin secretion-GRS [IS-GRS]）とインスリン分泌能および空腹時血糖値との関連は、全身持久力が高い者において弱まるかどうか、また、それらの関連はBMIが低い者においても認められるかどうかを明らかにすることを目的として研究を行った。
  2型糖尿病の既往歴のない中高齢者882名を対象とした横断研究を行った。IS-GRSはインスリン分泌能との関連が報告されている20個のSNPより求めた。全身持久力は最大酸素摂取量の測定により評価した。BMIの中央値（BMI = 22.6 kg/m2）で対象者を高BMI群と低BMI群に分類し、それぞれの群において解析を行った。その結果、高BMI群においてIS-GRSと全身持久力との間に有意な交互作用が認められ、全身持久力が低い者においてはIS-GRSとインスリン分泌能および空腹時血糖値との間に有意な関連が認められたが、全身持久力が高い者においてはこれらの関連は認められなかった。しかし、低BMI群においてこれらの交互作用は認められなかった。
  以上の結果より、インスリン分泌能と空腹時血糖値に及ぼす遺伝要因の影響は、BMIが低い者においては高い全身持久力を有していても弱まらない可能性が示唆された。

• 持久性運動直前の糖質摂取による運動誘発性低血糖（インスリン・ショック）の発生を規定する要因の解明

  Project Year :

  2016.04

  -

  2017.03

   

  谷澤 薫平

  Authorship： Principal investigator

• 時計遺伝子多型に基づく生活習慣病予防に向けた時間栄養学的研究

  Project Year :

  2016.04

  -

  2017.03

   

  谷澤 薫平

  Authorship： Principal investigator

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Specific Research 【 display / non-display 】

Specific Research 【 display / non-display 】

• 血清SPARC濃度と大腸ポリープおよび大腸がん発生の因果関係解明

  2020  

  　View Summary

  骨格筋から分泌されるマイオカイン"SPARC"は、大腸前がん細胞の増殖抑制作用を持つとされている。本研究の目的は、血中SPARC濃度と関連する一塩基多型（SNP）をゲノムワイド関連解析により同定し、それらを操作変数としたメンデルランダム化解析により血中SPARC濃度と大腸ポリープおよび大腸がん発生の因果関係を解明することである。本年度は中高齢男女1248名を対象として、一連の解析を実施するために必要なジェノタイプデータの取得、クオリティーコントロール、血中SPARC濃度の測定を実施した。クオリティーコントロールの結果、1219名、251,199個のSNPが解析対象となり、今後はこれらのデータを用いてゲノムワイド関連解析ならびにメンデルランダム化解析を進める。

• 筋量・体力と真に関連するマイオカインの同定と心血管代謝リスク因子との因果関係解明

  2019  

  　View Summary

  　本研究の目的は、筋量・体力に関連するマイオカインの血中濃度を規定する一塩基多型（SNP）をゲノムワイド関連解析により同定し、それらを操作変数としたメンデルランダム化解析により血中マイオカイン濃度と心血管代謝リスクの因果関係を解明することである。本年度は、これらの解析を実施するために必要なジェノタイプデータの取得とクオリティーコントロールを行った。　男女864名を対象としてジェノタイピングを行い、約55万個のSNPについてジェノタイプデータを取得した。PLINKによるクオリティーコントロールの結果、857名、251,125個のSNPが解析対象となった。今後はこの857名のデータを用いて各種解析を実施し、血中マイオカイン濃度と心血管代謝リスクの因果関係解明を目指す。 

Syllabus 【 display / non-display 】

Syllabus 【 display / non-display 】

• Sport Sciences 1 01

  Global Education Center

  2021   spring quarter

• Physical fitness and nutrition in health and sport sciences

  School of Sport Sciences

  2021   summer quarter

• Basic Seminar of Health Promotion

  School of Sport Sciences

  2021   spring semester

• X

  School of Sport Sciences

  2021   fall semester

• Biochemistry and Exercise Biochemistry

  School of Sport Sciences

  2021   fall semester

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Teaching Experience 【 display / non-display 】

Teaching Experience 【 display / non-display 】

• 健康スポーツ原論A（健康スポーツ生理・生化学）

  早稲田大学スポーツ科学部  

  2021

  -

  Now

   

• 演習IV（健康スポーツの生化学・遺伝学）

  早稲田大学スポーツ科学部  

  2021

  -

  Now

   

• 健康スポーツ基礎演習

  早稲田大学スポーツ科学部  

  2021

  -

  Now

   

• 演習III（健康スポーツの生化学・遺伝学）

  早稲田大学スポーツ科学部  

  2020

  -

  Now

   

• 演習II（健康スポーツの生化学・遺伝学）

  早稲田大学スポーツ科学部  

  2020

  -

  Now

   

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