田中 大器 (タナカ ダイキ)

写真a

所属

研究院(研究機関) ナノ・ライフ創新研究機構

職名

次席研究員(研究院講師)

兼担 【 表示 / 非表示

  • 理工学術院   大学院基幹理工学研究科

学歴 【 表示 / 非表示

  •  
    -
    2018年03月

    早稲田大学   大学院先進理工学研究科  

  •  
    -
    2014年03月

    東京理科大学   理学部第二部   化学科  

学位 【 表示 / 非表示

  • 博士

経歴 【 表示 / 非表示

  • 2019年04月
    -
    継続中

    早稲田大学   ナノ・ライフ創新研究機構   次席研究員

  • 2015年04月
    -
    2019年03月

    早稲田大学   ナノ・ライフ創新研究機構   研究助手

 

研究分野 【 表示 / 非表示

  • ナノマイクロシステム

研究キーワード 【 表示 / 非表示

  • マイクロ・ナノ化学

  • 機能性材料合成

  • 微細加工技術

論文 【 表示 / 非表示

  • Efficient Generation of Microdroplets Using Tail Breakup Induced with Multi-Branch Channels

    Daiki Tanaka, Satsuki Kajiya, Seito Shijo, Dong Hyun Yoon, Masahiro Furuya, Yoshito Nozaki, Hiroyuki Fujita, Tetsushi Sekiguchi, Shuichi Shoji

    Molecules   26 ( 12 ) 3707 - 3707  2021年06月  [査読有り]

    担当区分:筆頭著者, 責任著者

     概要を見る

    In recent years, research on the application of microdroplets in the fields of biotechnology and chemistry has made remarkable progress, but the technology for the stable generation of single-micrometer-scale microdroplets has not yet been established. In this paper, we developed an efficient and stable single-micrometer-scale droplet generation device based on the fragmentation of droplet tails, called “tail thread mode”, that appears under moderate flow conditions. This method can efficiently encapsulate microbeads that mimic cells and chemical products in passively generated single-micrometer-scale microdroplets. The device has a simple 2D structure; a T-junction is used for droplet generation; and in the downstream, multi-branch channels are designed for droplet deformation into the tail. Several 1–2 µm droplets were successfully produced by the tail’s fragmentation; this continuous splitting was induced by the branch channels. We examined a wide range of experimental conditions and found the optimal flow rate condition can be reduced to one-tenth compared to the conventional tip-streaming method. A mold was fabricated by simple soft lithography, and a polydimethylsiloxane (PDMS) device was fabricated using the mold. Based on the 15 patterns of experimental conditions and the results, the key factors for the generation of microdroplets in this device were examined. In the most efficient condition, 61.1% of the total droplets generated were smaller than 2 μm.

    DOI

  • Microdroplet synthesis of azo compounds with simple microfluidics-based pH control

    Daiki Tanaka, Shunsuke Sawai, Shohei Hattori, Yoshito Nozaki, Dong Hyun Yoon, Hiroyuki Fujita, Tetsushi Sekiguchi, Takashiro Akitsu, Shuichi Shoji

    RSC Advances   10 ( 64 ) 38900 - 38905  2020年  [査読有り]

    担当区分:筆頭著者, 責任著者

     概要を見る

    <p>Conventional solution-phase synthesis of azo compounds is complicated by the need for precise pH and temperature control, high concentrations of pH control reagents, and by-product removal. The microdroplet synthesis method has solved these problems.</p>

    DOI

  • Development of Microdroplet Generation Method for Organic Solvents Used in Chemical Synthesis

    Shohei Hattori, Chenghe Tang, Daiki Tanaka, Dong Hyun Yoon, Yoshito Nozaki, Hiroyuki Fujita, Takashiro Akitsu, Tetsushi Sekiguchi, Shuichi Shoji

    Molecules   25 ( 22 ) 5360 - 5360  2020年11月  [査読有り]

     概要を見る

    Recently, chemical operations with microfluidic devices, especially droplet-based operations, have attracted considerable attention because they can provide an isolated small-volume reaction field. However, analysis of these operations has been limited mostly to aqueous-phase reactions in water droplets due to device material restrictions. In this study, we have successfully demonstrated droplet formation of five common organic solvents frequently used in chemical synthesis by using a simple silicon/glass-based microfluidic device. When an immiscible liquid with surfactant was used as the continuous phase, the organic solvent formed droplets similar to water-in-oil droplets in the device. In contrast to conventional microfluidic devices composed of resins, which are susceptible to swelling in organic solvents, the developed microfluidic device did not undergo swelling owing to the high chemical resistance of the constituent materials. Therefore, the device has potential applications for various chemical reactions involving organic solvents. Furthermore, this droplet generation device enabled control of droplet size by adjusting the liquid flow rate. The droplet generation method proposed in this work will contribute to the study of organic reactions in microdroplets and will be useful for evaluating scaling effects in various chemical reactions.

    DOI

  • Integration of Horizontal and Vertical Microfluidic Modules for Core-Shell Droplet Generation and Chemical Application

    Dong Hyun Yoon, Yoshito Nozaki, Daiki Tanaka, Tetsushi Sekiguchi, Shuichi Shoji

    Micromachines   10 ( 613 )  2019年09月  [査読有り]

  • Size-Dependent and Property-Independent Passive Microdroplet Sorting by Droplet Transfer on Dot Rails

    D.H. Yoon, D. Tanaka, T. Sekiguchi, S. Shoji

    Micromachines   9 ( 10 )  2018年10月  [査読有り]

    DOI

全件表示 >>

講演・口頭発表等 【 表示 / 非表示

  • ESTABLISHMENT OF LABO-IN-A-MICRODROPLET FOR AZO COMPOUND SYNTHESIS

    D. Tanaka, S. Sawai, T. Sugaya, Y. Nozaki, D. H. Yoon, T. Isano, H. Yamagata, H. Fujita, T. Sekiguchi, T. Akitsu, S. Shoji

    23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences  

    発表年月: 2020年10月

  • High Efficient Synthesis of Functional Compounds by Microfluidic Device

    D. Tanaka, D. H. Yoon, Y. Nozaki, T. Sekiguchi, T. Akitsu, S. Shoji

    International Symposium iLIM4  

    発表年月: 2019年10月

  • CONSTRUCTION OF A WELL-OPERABLE CRYSTALLIZATION METHOD FOR CHEMICAL ANALYSIS APPLYING MICRODROPLET DEVICE

    S. Hattori, D. Tanaka, D. H. Yoon, T. Sekiguchi, Y. Nozaki, T. Akitsu, S. Shoji

    THE 4TH CONFERENCE ON MICROFLUIDIC HANDLING SYSTEMS  

    発表年月: 2019年10月

  • HIGH-EFFICIENCY DIBROMINATION OF ORGANIC COMPOUND IN MICROFLUIDIC CHANNEL OF SI PILLAR ARRAY DIRECTLY COATED WITH IRON CATALYST

    T. Sugaya, D. Tanaka, D. H. Yoon, Y. Nozaki, T. Sekiguchi, T. Akitsu, S. Shoji

    Transducers 2019  

    発表年月: 2019年06月

    開催年月:
    2019年06月
     
     
  • マイクロ流体デバイスによる高効率かつ安全なブロモ基付加操作

    川久保 渉, 田中 大器, 尹 棟鉉, 関口 哲志, 高橋 啓太, 秋津 貴城, 庄子 習一

    「センサ・マイクロマシンと応用システム」シンポジウム  

    発表年月: 2017年10月

全件表示 >>

 

現在担当している科目 【 表示 / 非表示

  • MEMS

    大学院基幹理工学研究科

    2021年   春学期

  • MEMS

    大学院先進理工学研究科

    2021年   春学期

  • MEMS

    基幹理工学部

    2021年   春学期