Concurrent Post
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Affiliated organization Global Education Center
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Faculty of Science and Engineering Graduate School of Advanced Science and Engineering
Details of a Researcher
Updated on 2022/08/17
Affiliated organization Global Education Center
Faculty of Science and Engineering Graduate School of Advanced Science and Engineering
理工学術院総合研究所 兼任研究員
スマートライフサイエンス研究所 プロジェクト研究所所長
京都大学 博士(理学)
Biophysics
Clock Gene Expression in the Eye Exhibits Circadian Oscillation and Light Responsiveness but is Not Necessary for Nocturnal Locomotor Activity of Japanese Loach, Misgurnus anguillicaudatus.
Yuya Saratani, Yuki Takeuchi, Keiko Okano, Toshiyuki Okano
Zoological science 37 ( 2 ) 177 - 192 2020.04 [Domestic journal]
Moonlight controls lunar-phase-dependency and regular oscillation of clock gene expressions in a lunar-synchronized spawner fish, Goldlined spinefoot
Yuki Takeuchi, Ryo Kabutomori, Chihiro Yamauchi, Hitomi Miyagi, Akihiro Takemura, Keiko Okano, Toshiyuki Okano
Scientific Reports 8 ( 1 ) 6208 2018.12 [Refereed]
Light- and circadian-controlled genes respond to a broad light spectrum in Puffer Fish-derived Fugu eye cells
Keiko Okano, Shoichi Ozawa, Hayao Sato, Sawa Kodachi, Masaharu Ito, Toshiaki Miyadai, Akihiro Takemura, Toshiyuki Okano
SCIENTIFIC REPORTS 7 46150 2017.04 [Refereed]
Rhodopsin in the Dark Hot Sea: Molecular Analysis of Rhodopsin in a Snailfish, Careproctus rhodomelas, Living near the Deep-Sea Hydrothermal Vent
Rie Sakata, Ryo Kabutomori, Keiko Okano, Hiromasa Mitsui, Akihiro Takemura, Tetsuya Miwa, Hiroyuki Yamamoto, Toshiyuki Okano
PLOS ONE 10 ( 8 ) e0135888 2015.08 [Refereed]
Overexpression in Yeast, Photocycle, and in Vitro Structural Change of an Avian Putative Magnetoreceptor Cryptochrome4
Hiromasa Mitsui, Toshinori Maeda, Chiaki Yamaguchi, Yusuke Tsuji, Ryuji Watari, Yoko Kubo, Keiko Okano, Toshiyuki Okano
BIOCHEMISTRY 54 ( 10 ) 1908 - 1917 2015.03 [Refereed]
Hypothalamic Expression and Moonlight-Independent Changes of Cry3 and Per4 Implicate Their Roles in Lunar Clock Oscillators of the Lunar-Responsive Goldlined Spinefoot
Riko Toda, Keiko Okano, Yuki Takeuchi, Chihiro Yamauchi, Masato Fukushiro, Akihiro Takemura, Toshiyuki Okano
PLOS ONE 9 ( 10 ) e109119 2014.10 [Refereed]
Identification and Characterization of Cryptochrome4 in the Ovary of Western Clawed Frog Xenopus tropicalis
Takahiro Takeuchi, Yoko Kubo, Keiko Okano, Toshiyuki Okano
ZOOLOGICAL SCIENCE 31 ( 3 ) 152 - 159 2014.03 [Refereed]
Okano Toshiyuki
Seibutsu Butsuri 54 ( 1 ) S134 2014
Light-dependent Structural Change of Chicken Retinal Cryptochrome4
Ryuji Watari, Chiaki Yamaguchi, Wataru Zemba, Yoko Kubo, Keiko Okano, Toshiyuki Okano
JOURNAL OF BIOLOGICAL CHEMISTRY 287 ( 51 ) 42634 - 42641 2012.12 [Refereed]
Zebrafish respond to the geomagnetic field by bimodal and group-dependent orientation
Akira Takebe, Toshiki Furutani, Tatsunori Wada, Masami Koinuma, Yoko Kubo, Keiko Okano, Toshiyuki Okano
SCIENTIFIC REPORTS 2 727 2012.10 [Refereed]
Lunar Phase-Dependent Expression of Cryptochrome and a Photoperiodic Mechanism for Lunar Phase-Recognition in a Reef Fish, Goldlined Spinefoot
Masato Fukushiro, Takahiro Takeuchi, Yuki Takeuchi, Sung-Pyo Hur, Nozomi Sugama, Akihiro Takemura, Yoko Kubo, Keiko Okano, Toshiyuki Okano
PLOS ONE 6 ( 12 ) e28643 2011.12 [Refereed]
Cryptochrome Genes Are Highly Expressed in the Ovary of the African Clawed Frog, Xenopus tropicalis
Yoko Kubo, Takahiro Takeuchi, Keiko Okano, Toshiyuki Okano
PLOS ONE 5 ( 2 ) e9273 2010.02 [Refereed]
Transcriptional repressor TIEG1 regulates Bmal1 gene through GC box and controls circadian clockwork
Tsuyoshi Hirota, Naohiro Kon, Takashi Itagaki, Naosuke Hoshina, Toshiyuki Okano, Yoshitaka Fukada
GENES TO CELLS 15 ( 2 ) 111 - 121 2010.02 [Refereed]
Preferential Inhibition of BMAL2-CLOCK Activity by PER2 Reemphasizes Its Negative Role and a Positive Role of BMAL2 in the Circadian Transcription
Momoko Sasaki, Hikari Yoshitane, Ngoc-Hien Du, Toshiyuki Okano, Yoshitaka Fukada
JOURNAL OF BIOLOGICAL CHEMISTRY 284 ( 37 ) 25149 - 25159 2009.09 [Refereed]
Roles of CLOCK Phosphorylation in Suppression of E-Box-Dependent Transcription
Hikari Yoshitane, Toshifumi Takao, Yoshinori Satomi, Ngoc-Hien Du, Toshiyuki Okano, Yoshitaka Fukada
MOLECULAR AND CELLULAR BIOLOGY 29 ( 13 ) 3675 - 3686 2009.07 [Refereed]
Macrophage inhibitory cytokine MIC-1 is upregulated by short-wavelength light in cultured normal human dermal fibroblasts
Masashi Akiyama, Keiko Okano, Yoshitaka Fukada, Toshiyuki Okano
FEBS LETTERS 583 ( 5 ) 933 - 937 2009.03 [Refereed]
Circadian clock gene regulation of steroidogenic acute regulatory protein gene expression in preovulatory ovarian follicles
Nobuhiro Nakao, Shinobu Yasuo, Atsuko Nishimura, Takashi Yamamura, Tsuyoshi Watanabe, Tsubasa Anraku, Toshiyuki Okano, Yoshitaka Fukada, Peter J. Sharp, Shizufumi Ebihara, Takashi Yoshimura
ENDOCRINOLOGY 148 ( 7 ) 3031 - 3038 2007.07 [Refereed]
Two isoforms of chicken melanopsins show blue light sensitivity
Torii M, Kojima D, Okano T, Nakamura A, Terakita A, Shichida Y, Wada A, Fukada Y
FEBS Lett. 581 5327 - 5331 2007 [Refereed]
GRK1 and GRK7: Unique cellular distribution and widely different activities of opsin phosphorylation in the zebrafish rods and cones
Yasutaka Wada, Junichi Sugiyama, Toshiyuki Okano, Yoshitaka Fukada
JOURNAL OF NEUROCHEMISTRY 98 ( 3 ) 824 - 837 2006.08 [Refereed]
Molecular cloning, mRNA expression, and immunocytochemical localization of a putative blue-light photoreceptor CRY4 in the chicken pineal glandnn
Y Kubo, M Akiyama, Y Fukada, T Okano
JOURNAL OF NEUROCHEMISTRY 97 ( 4 ) 1155 - 1165 2006.05 [Refereed]
Lcg is a light-inducible and clock-controlled gene expressed in the chicken pineal gland
M Hatori, T Okano, Y Nakajima, M Doi, Y Fukada
JOURNAL OF NEUROCHEMISTRY 96 ( 6 ) 1790 - 1800 2006.03 [Refereed]
[Protein phosphorylation-dependent regulation of circadian timekeeping].
Doi M, Okano T
Seikagaku. The Journal of Japanese Biochemical Society 77 ( 2 ) 125 - 129 2005.02 [Refereed]
Farnesylation of retinal transducin underlies its translocation during light adaptation
Kassai H, Aiba A, Nakao K, Nakamura K, Katsuki M, Xiong W.H, Yau K. W, Imai H, Shichida Y, Satomi Y, Takao T, Okano, T, Fukada, Y
Neuron 47 529 - 539 2005 [Refereed]
Negative control of circadian clock regulator E4BP4 by casein kinase I epsilon-mediated phosphorylation
M Doi, T Okano, Yujnovsky, I, P Sassone-Corsi, Y Fukada
CURRENT BIOLOGY 14 ( 11 ) 975 - 980 2004.06 [Refereed]
Light-Dependent Expression of Pinopsin Gene in Chicken Pineal Gland
Yoko Takanaka, Toshiyuki Okano, Masayuki Iigo, Yoshitaka Fukada
Journal of Neurochemistry 70 ( 3 ) 908 - 913 2002.11
Glucose down-regulates Per1 and Per2 mRNA levels and induces circadian gene expression in cultured rat-1 fibroblasts
T Hirota, T Okano, K Kokame, H Shirotani-Ikejima, T Miyata, Y Fukada
JOURNAL OF BIOLOGICAL CHEMISTRY 277 ( 46 ) 44244 - 44251 2002.11 [Refereed]
Opsin-G(11)-mediated signaling pathway for photic entrainment of the chicken pineal circadian clock
T Kasahara, T Okano, T Haga, Y Fukada
JOURNAL OF NEUROSCIENCE 22 ( 17 ) 7321 - 7325 2002.09 [Refereed]
A negative regulatory element required for light-dependent pinopsin gene expression
Y Takanaka, T Okano, K Yamamoto, Y Fukada
JOURNAL OF NEUROSCIENCE 22 ( 11 ) 4357 - 4363 2002.06 [Refereed]
Light-dependent changes in the chick pineal temperature and the expression of cHsp90 alpha gene: A potential contribution of in vivo temperature change to the photic-entrainment of the chick pineal circadian clock
M Doi, Y Nakajima, T Okano, Y Fukada
ZOOLOGICAL SCIENCE 19 ( 6 ) 633 - 641 2002.06 [Refereed]
Mitogen-activated protein kinase phosphorylates and negatively regulates basic helix-loop-helix-PAS transcription factor BMAL1
Sanada K, Okano T, Fukada Y
J. Biol. Chem. 277 266 - 271 2002 [Refereed]
in vivoマイクロダイアリシス法を用いた鳥類の脳脊髄液中のメラトニン概日リズムのラジオイムノアッセイ解析
東京大学アイソトープ総合センターニュース 32 ( 4 ) 2 - 4 2002
体内時計の時刻を調節する遺伝子の発見
生物の科学 遺伝 56 ( 2 ) 26 - 28 2002
Chicken pineal Cry genes: Light-dependent up-regulation of cCry1 and cCry2 transcripts
K Yamamoto, T Okano, Y Fukada
NEUROSCIENCE LETTERS 313 ( 1-2 ) 13 - 16 2001.11 [Refereed]
Chicken pineal clock genes: implication of BMAL2 as a bidirectional regulator in circadian clock oscillation
T Okano, K Yamamoto, K Okano, T Hirota, T Kasahara, M Sasaki, Y Takanaka, Y Fukada
GENES TO CELLS 6 ( 9 ) 825 - 836 2001.09 [Refereed]
Light-induced phase-delay of the chicken pineal circadian clock is associated with the induction of cE4bp4, a potential transcriptional repressor of cPer2 gene
M Doi, Y Nakajima, T Okano, Y Fukada
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98 ( 14 ) 8089 - 8094 2001.07 [Refereed]
Immunohistochemical localization of opsins and alpha-subunit of transducin in the pineal complex and deep brain of the Japanese grass lizard, Takydromus tachydromoides
T Yoshikawa, T Okano, K Kokame, O Hisatomi, F Tokunaga, T Oishi, Y Fukada
ZOOLOGICAL SCIENCE 18 ( 3 ) 325 - 330 2001.04 [Refereed]
Cloning of mouse BMAL2 and its daily expression profile in the suprachiasmatic nucleus: a remarkable acceleration of Bmal2 sequence divergence after Bmal gene duplication
T Okano, M Sasaki, Y Fukada
NEUROSCIENCE LETTERS 300 ( 2 ) 111 - 114 2001.03 [Refereed]
Regulatory mechanism for the stability of the meta II intermediate of pinopsin
A Nakamura, D Kojima, T Okano, H Imai, A Terakita, Y Shichida, Y Fukada
JOURNAL OF BIOCHEMISTRY 129 ( 2 ) 329 - 334 2001.02 [Refereed]
Effect of brefeldin A on melatonin secretion of chick pineal cells
T Hirota, S Kagiwada, T Kasahara, T Okano, M Murata, Y Fukada
JOURNAL OF BIOCHEMISTRY 129 ( 1 ) 51 - 59 2001.01 [Refereed]
鳥類松果体細胞の概日時計システム
細胞工学 20 ( 6 ) 837 - 842 2001
Phototransduction molecules in the pigeon deep brain
Y Wada, T Okano, Y Fukada
JOURNAL OF COMPARATIVE NEUROLOGY 428 ( 1 ) 138 - 144 2000.12 [Refereed]
Rod-type transducin alpha-subunit mediates a phototransduction pathway in the chicken pineal gland
T Kasahara, T Okano, T Yoshikawa, K Yamazaki, Y Fukada
JOURNAL OF NEUROCHEMISTRY 75 ( 1 ) 217 - 224 2000.07 [Refereed]
Colocalization of pinopsin with two types of G-protein alpha-subunits in the chicken pineal gland
A Matsushita, T Yoshikawa, T Okano, T Kasahara, Y Fukada
CELL AND TISSUE RESEARCH 299 ( 2 ) 245 - 251 2000.02 [Refereed]
Diversity of opsin immunoreactivities in the extraretinal tissues of four anuran amphibians
K Okano, T Okano, T Yoshikawa, A Masuda, Y Fukada, T Oishi
JOURNAL OF EXPERIMENTAL ZOOLOGY 286 ( 2 ) 136 - 142 2000.02 [Refereed]
Role of circadian activation of mitogen-activated protein kinase in chick pineal clock oscillation
K Sanada, Y Hayashi, Y Harada, T Okano, Y Fukada
JOURNAL OF NEUROSCIENCE 20 ( 3 ) 986 - 991 2000.02 [Refereed]
Photoreceptors in pineal gland and brain: Cloning, localization, and overexpression
T Okano, Y Fukada
VERTEBRATE PHOTOTRANSDUCTION AND THE VISUAL CYCLE, PT B 316 278 - 291 2000 [Refereed]
Chimeric nature of pinopsin between rod and cone visual pigments
A Nakamura, D Kojima, H Imai, A Terakita, T Okano, Y Shichida, Y Fukada
BIOCHEMISTRY 38 ( 45 ) 14738 - 14745 1999.11 [Refereed]
Differentiation of pinopsin-immunoreactive cells in the developing quail pineal organ: an in-vivo and in-vitro immunohistochemical study
M Yamao, M Araki, T Okano, Y Fukada, T Oishi
CELL AND TISSUE RESEARCH 296 ( 3 ) 667 - 671 1999.06 [Refereed]
時計細胞の時刻を可視化する(共著)
バイオイメージング 7 ( 4 ) 221 - 226 1999
脳内光レセプター(共著)
生物物理 ( 224 ) 246 - 249 1999
色覚の進化(共著)
遺伝 53 ( 9 ) 39 - 44 1999
Molecular cloning and characterization of a cDNA encoding the retinal arylalkylamine N-acetyltransferase of the rainbow trout, Oncorhynchus mykiss
K Mizusawa, M Iigo, H Suetake, Y Yoshiura, K Gen, K Kikuchi, T Okano, Y Fukada, K Aida
ZOOLOGICAL SCIENCE 15 ( 3 ) 345 - 351 1998.06 [Refereed]
Light-dependent expression of pinopsin gene in chicken pineal gland
Y Takanaka, T Okano, M Iigo, Y Fukada
JOURNAL OF NEUROCHEMISTRY 70 ( 3 ) 908 - 913 1998.03 [Refereed]
Identification of rhodopsin in the pigeon deep brain
Y Wada, T Okano, A Adachi, S Ebihara, Y Fukada
FEBS LETTERS 424 ( 1-2 ) 53 - 56 1998.03 [Refereed]
A deep brain photoreceptive molecule in the toad hypothalamus
T Yoshikawa, T Okano, T Oishi, Y Fukada
FEBS LETTERS 424 ( 1-2 ) 69 - 72 1998.03 [Refereed]
Immunocytochemical identification of pinopsin in pineal glands of chicken and pigeon
T Okano, Y Takanaka, A Nakamura, K Hirunagi, A Adachi, S Ebihara, Y Fukada
MOLECULAR BRAIN RESEARCH 50 ( 1-2 ) 190 - 196 1997.10 [Refereed]
Immunoelectron-microscopic investigation of the subcellular localization of pinopsin in the pineal organ of the chicken
K Hirunagi, S Ebihara, T Okano, Y Takanaka, Y Fukada
CELL AND TISSUE RESEARCH 289 ( 2 ) 235 - 241 1997.08 [Refereed]
Molecular cloning of heterotrimeric G-protein alpha-subunits in chicken pineal gland
T Okano, K Yamazaki, T Kasahara, Y Fukada
JOURNAL OF MOLECULAR EVOLUTION 44 S91 - S97 1997 [Refereed]
動物の体内時計(共著)
科学 67 ( 1 ) 48 - 56 1997
概日時計の同調因子ピノプシンの構造・機能・発現調節(共著)
生物物理 36 ( 2 ) 101 - 103 1996
PRIMARY STRUCTURE OF A GAMMA-SUBUNIT OF G-PROTEIN, GAMMA(12), AND ITS PHOSPHORYLATION BY PROTEIN-KINASE-C
R MORISHITA, H NAKAYAMA, T ISOBE, T MATSUDA, Y HASHIMOTO, T OKANO, Y FUKADA, K MIZUNO, S OHNO, O KOZAWA, K KATO, T ASANO
JOURNAL OF BIOLOGICAL CHEMISTRY 270 ( 49 ) 29469 - 29475 1995.12 [Refereed]
PURIFICATION AND LOW-TEMPERATURE SPECTROSCOPY OF GECKO VISUAL PIGMENTS GREEN AND BLUE
D KOJIMA, H IMAI, T OKANO, Y FUKADA, F CRESCITELLI, T YOSHIZAWA, Y SHICHIDA
BIOCHEMISTRY 34 ( 3 ) 1096 - 1106 1995.01 [Refereed]
視物質の多様化と視覚の進化(共著)
細胞工学 14 ( 9 ) 1007 - 1014 1995
脳は光を感じる「第三の目」生物の一日のリズムをつかさどる体内時計のなぞ(共著)
ニュートン(教育社) 15 102 - 107 1995
分子レベルにおける生物時計機構の解析(共著)
67 1137 - 1142 1995
生物時計の時刻合わせをする脳内タンパク質(共著)
遺伝 19 ( 4 ) 8 1995
脳内光受容体ピノプシンと生物時計(共著)
生物科学ニュース ( 278 ) 14 - 16 1995
PINOPSIN IS A CHICKEN PINEAL PHOTORECEPTIVE MOLECULE
T OKANO, T YOSHIZAWA, Y FUKADA
NATURE 372 ( 6501 ) 94 - 97 1994.11 [Refereed]
PHOTOSENSITIVITIES OF IODOPSIN AND RHODOPSINS
T OKANO, Y FUKADA, Y SHICHIDA, T YOSHIZAWA
PHOTOCHEMISTRY AND PHOTOBIOLOGY 56 ( 6 ) 995 - 1001 1992.12 [Refereed]
CONE VISUAL PIGMENTS ARE PRESENT IN GECKO ROD CELLS
D KOJIMA, T OKANO, Y FUKADA, Y SHICHIDA, T YOSHIZAWA, TG EBREY
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 89 ( 15 ) 6841 - 6845 1992.08 [Refereed]
PRIMARY STRUCTURES OF CHICKEN CONE VISUAL PIGMENTS - VERTEBRATE RHODOPSINS HAVE EVOLVED OUT OF CONE VISUAL PIGMENTS
T OKANO, D KOJIMA, Y FUKADA, Y SHICHIDA, T YOSHIZAWA
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 89 ( 13 ) 5932 - 5936 1992.07 [Refereed]
錐体視物質の一次構造:ロドプシンは錐体視物質から進化した(共著)
生物物理 32 ( 5 ) 273 - 276 1992
PHOSPHORYLATION OF IODOPSIN, CHICKEN RED-SENSITIVE CONE VISUAL PIGMENT
Y FUKADA, K KOKAME, T OKANO, Y SHICHIDA, T YOSHIZAWA, JH MCDOWELL, PA HARGRAVE, K PALCZEWSKI
BIOCHEMISTRY 29 ( 43 ) 10102 - 10106 1990.10 [Refereed]
THE PRIMARY STRUCTURE OF IODOPSIN, A CHICKEN RED-SENSITIVE CONE PIGMENT
O KUWATA, Y IMAMOTO, T OKANO, K KOKAME, D KOJIMA, H MATSUMOTO, A MORODOME, Y FUKADA, Y SHICHIDA, K YASUDA, Y SHIMURA, T YOSHIZAWA
FEBS LETTERS 272 ( 1-2 ) 128 - 132 1990.10 [Refereed]
COMPARATIVE-STUDY ON THE CHROMOPHORE BINDING-SITES OF ROD AND RED-SENSITIVE CONE VISUAL PIGMENTS BY USE OF SYNTHETIC RETINAL ISOMERS AND ANALOGS
Y FUKADA, T OKANO, Y SHICHIDA, T YOSHIZAWA, A TREHAN, D MEAD, M DENNY, AE ASATO, RSH LIU
BIOCHEMISTRY 29 ( 12 ) 3133 - 3140 1990.03 [Refereed]
錐体の光感受性レチナール蛋白質アイオドプシンの精製とその局在(共著)
ビタミン 64 ( 10 ) 614 - 615 1990
EFFECT OF CHLORIDE-ION ON THE THERMAL DECAY PROCESS OF THE BATHO INTERMEDIATE OF IODOPSIN AT LOW-TEMPERATURE
Y IMAMOTO, H KANDORI, T OKANO, Y FUKADA, Y SHICHIDA, T YOSHIZAWA
BIOCHEMISTRY 28 ( 24 ) 9412 - 9416 1989.11 [Refereed]
PURIFICATION OF CONE VISUAL PIGMENTS FROM CHICKEN RETINA
T OKANO, Y FUKADA, ID ARTAMONOV, T YOSHIZAWA
BIOCHEMISTRY 28 ( 22 ) 8848 - 8856 1989.10 [Refereed]
CHICKEN RED-SENSITIVE CONE VISUAL PIGMENT RETAINS A BINDING DOMAIN FOR TRANSDUCIN
Y FUKADA, T OKANO, ID ARTAMONOV, T YOSHIZAWA
FEBS LETTERS 246 ( 1-2 ) 69 - 72 1989.03 [Refereed]
光受容タンパク質の分子進化(共著)
遺伝 49 ( 12 ) 28 - 34
生物時計の分子生物学(分担)
シュプリンガー・フェアラーク東京 1999
試験監督のいない学校(分担)
東方出版 1996
ピノプシンによる光シグナル伝達と生物時計(共著) 「細胞内シグナル伝達のしくみ」(分担)
羊土社・新臨床医のための分子医学シリーズ 1996
視覚の分子生物学:図説分子病態学(共著)
中外医学社 1995
視細胞における色受容:その分子機構と進化(共著) 視覚の進化と脳
朝倉書店 1992
概日時計の異なる段階におけるCLOCKとBMAL1の周期的リン酸化(Rhythmic phosphorylation of CLOCK and BMAL1 at different phases of circadian clock)
吉種 光, 高尾 敏文, ズ・ゴク・ヒエン, 岡野 俊行, 深田 吉孝
日本生化学会大会プログラム・講演要旨集 82回 4P - 461 2009.09
Ser38/Ser42 phosphorylation of CLOCK critical for its DNA-binding and suppression of E-box-dependent transcription
吉種光, 高尾敏文, 里見佳典, ズ ゴク‐ヒエン, 岡野俊行, 深田吉孝
Program Abstr 6th Congr Asian Sleep Res Soc 34th Annu Meet Jpn Soc Sleep Res 16th Annu Meet Jpn Soc Chronobiol Jt Congr 2009 242 2009
ファルネシル欠失トランスデューシンγサブユニットを発現する視細胞の光応答解析
小島 大輔, 葛西 秀俊, 櫻井 啓輔, 岡野 俊行, 今井 啓雄, 中尾 和貴, 中谷 敬, 七田 芳則, 饗場 篤, 深田 吉孝
日本生化学会大会・日本分子生物学会年会合同大会講演要旨集 81回・31回 2T15 - 9 2008.11
概日時計作働におけるCLOCKの転写促進の抑圧におけるCLOCKリン酸化の重要な役割(CLOCK phosphorylation plays a key role for the suppression of its transactivation in circadian clockwork)
吉種 光, 岡野 俊行, 深田 吉孝
日本生化学会大会・日本分子生物学会年会合同大会講演要旨集 81回・31回 4T16 - 2 2008.11
Phosphorylation of CLOCK and BMAL1 in circadian oscillation systems
吉種光, 岡野俊行, 深田吉孝
生化学 1P-0921 2007
Light-regulated genes in the cultured dermal fibroblasts
Masashi Akiyama, Yoshitaka Fukada, Toshiyuki Okano
ZOOLOGICAL SCIENCE 23 ( 12 ) 1201 - 1201 2006.12
Research paper, summary (international conference)
Cryptochrome is expressed in the chicken retinal photoreceptor cells
Toshiyuki Okano, Yoko Kubo, Masashi Akiyama, Yoshitaka Fukada
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY 145 ( 3-4 ) 420 - 421 2006.11
Research paper, summary (international conference)
Molecular characterization of circadian clock regulators by using monoclonal antibodies against CLOCK and BMAL1
YOSHITANE Hikari, OKANO Toshiyuki, KOMORI Munenori, FUKADA Yoshitaka
生化学 A13704(3P-B-190) 2006
光から時計遺伝子への分子機構.
岡野俊行, 深田吉孝
医学のあゆみ 特集『時計遺伝子』 医歯薬出版. 216 211 - 214 2006
A clock-related gene Lcg expressed in the chicken pineal gland
Megumi Hatori, Toshiyuki Okano, Yoshito Nakajima, Masao Doi, Yoshitaka Fukada
ZOOLOGICAL SCIENCE 22 ( 12 ) 1490 - 1490 2005.12
Research paper, summary (international conference)
Enzymatic properties of the opsin kinase in the zebrafish cone cells
Yasutaka Wada, Junichi Sugiyama, Toshiyuki Okano, Yoshie Shimauchi-Matsukawa, Satoru Kawamura, Yoshitaka Fukada
ZOOLOGICAL SCIENCE 22 ( 12 ) 1476 - 1476 2005.12
Research paper, summary (international conference)
Functional role of melatonin in the formation of circadian rhythms in the zebrafish
Toshiyuki Okano, Yoshitaka Fukada
ZOOLOGICAL SCIENCE 22 ( 12 ) 1423 - 1424 2005.12
Research paper, summary (international conference)
Localization of CRY4, a novel blue-light photoreceptor-like protein, in the chicken pineal gland
Yoko Kubo, Masashi Akiyama, Yoshitaka Fukada, Toshiyuki Okano
ZOOLOGICAL SCIENCE 22 ( 12 ) 1476 - 1476 2005.12
Research paper, summary (international conference)
Characterization of monoclonal antibodies against circadian clock regulator, CLOCK-BMAL1 complex
YOSHITANE Hikari, OKANO Toshiyuki, KOMORI Munenori, FUKADA Yoshitaka
生化学 77 ( 8 ) 993 2005.08
A novel photoreceptor candidate expressed in the chicken retina and pineal gland
Yoko Kubo, Masashi Akiyama, Yoshitaka Fukada, Toshiyuki Okano
ZOOLOGICAL SCIENCE 21 ( 12 ) 1308 - 1308 2004.12
Research paper, summary (international conference)
Entrainment of circadian clocks in birds: Molecular mechanisms of light-dependent phase shifts
Toshiyuki Okano, Yoshitaka Fukada
ZOOLOGICAL SCIENCE 21 ( 12 ) 1236 - 1237 2004.12
Research paper, summary (international conference)
ゼブラフィッシュ眼球におけるオプシンキナーゼの発現量の比較(Expression levels of opsin kinases in the zebrafish eye)
和田 恭高, 杉山 純一, 岡野 俊行, 松川 淑恵, 河村 悟, 深田 吉孝
神経化学 43 ( 2-3 ) 384 - 384 2004.08
2SC04 Regulation of Light Signaling in Rod Cells by G-protein βγ Complex
Kassai H, Aiba A, Nakao K, Nakamuta K, Katsuki M, Xiong Wei-Hone, Yau Kine-Wai, Imai H, Shichida Y, Takao T, Okano T, Fukada Y
Seibutsu Butsuri 44 ( 0 ) 2004
Okano Toshiyuki, Ikeda Takamasa, Imazato Kazuyuki, Mano Hiroaki, Fukada Yoshitaka
Zoological science 20 ( 12 ) 1593 - 1593 2003
Hatori Megumi, Okano Toshiyuki, Nakajima Yoshito, Doi Masao, Fukada Yoshitaka
Zoological science 20 ( 12 ) 1593 - 1593 2003
分子時計の生化学 グルコース投与によるrat-1細胞の時計遺伝子発現における概日リズムの誘導
広田 毅, 岡野 俊行, 小亀 浩市, 池島 裕子, 谷, 宮田 敏行, 深田 吉孝
生化学 74 ( 8 ) 643 - 643 2002.08
Imazato Kazuyuki, Okano Toshiyuki, Mano Hiroaki, Fukada Yoshitaka
Zoological science 19 ( 12 ) 1460 - 1460 2002
Okano Toshiyuki, Sanada Kamon, Fukada Yoshitaka
Zoological science 19 ( 12 ) 1460 - 1460 2002
Circadian clock system in the pineal gland.
Yoshitaka Fukada, Toshiyuki Okano
Mol. Neurobiol. 25 19 - 30 2002
概日時計の光位相制御に関わる転写因子E4BP4の同定
土居 雅夫, 中島 芳人, 岡野 俊行, 深田 吉孝
神経化学 40 ( 2-3 ) 291 - 291 2001.09
ニワトリ松果体における概日時計の光位相シフトに関わる転写抑制因子E4BP4
岡野 俊行, 土居 雅夫, 中島 芳人, 深田 吉孝
生化学 73 ( 8 ) 719 - 719 2001.08
W4-4 Chick Pineal Circadian Clock : The Clock Genes and Photoentrainment. :
OKANO Toshiyuki, FUKADA Yoshitaka
Acta histochemica et cytochemica 34 ( 1 ) 58 - 58 2001
Doi M., Nakajima Y., Okano T., Fukada Y.
Zoological science 18 112 - 112 2001
生体リズムの研究法 松果体の概日時計研究
岡野 俊行, 深田 吉孝
日本組織細胞化学会総会・学術集会講演プログラム・予稿集 41回 70 - 70 2000.12
ニワトリ松果体の概日時計構成分子cBMAL2
岡野 俊行, 山本 和幸, 岡野 恵子, 広田 毅, 佐々木 桃子, 高中 陽子, 深田 吉孝
日本時間生物学会会誌: Journal of Chronobiology 6 ( 2 ) 87 - 87 2000.10
松果体細胞における光受容とG11を介する光情報伝達経路
笠原 和起, 岡野 俊行, 吉川 朋子, 松下 敦子, 芳賀 達也, 深田 吉孝
生物物理 40 ( Suppl.1 ) S36 - S36 2000.08
哺乳類の時計遺伝子候補Bmal2(Arnt4)の同定
佐々木 桃子, 岡野 俊行, 深田 吉孝
生化学 72 ( 8 ) 1016 - 1016 2000.08
ブレフェルジンAを用いたニワトリ松果体細胞のメラトニン分泌機構の解析
広田 毅, 鍵和田 聡, 笠原 和起, 岡野 俊行, 村田 昌之, 深田 吉孝
生化学 72 ( 8 ) 1016 - 1016 2000.08
概日時計の光位相シフトに関与する遺伝子の探索
土居 雅夫, 中島 芳人, 岡野 俊行, 深田 吉孝
生化学 72 ( 8 ) 1016 - 1016 2000.08
ニワトリ時計遺伝子のクローニングと機能解析
山本 和幸, 岡野 俊行, 岡野 恵子, 高中 陽子, 深田 吉孝
生化学 72 ( 8 ) 1015 - 1015 2000.08
Role of second extracellular loop of pinopsin in stabilization of metapinopsin II
Nakamura A, Kojima D, Okano T, Imai H, Terakita A, Shichida Y, Fukada Y
Seibutsu Butsuri 40 ( 0 ) 2000
ニワトリ松果体におけるピノプシン遺伝子の光発現誘導
岡野 俊行, 高中 陽子, 深田 吉孝
日本時間生物学会会誌: Journal of Chronobiology 5 ( 2 ) 51 - 51 1999.10
概日時計が局在する松果体および網膜におけるMAPキナーゼ活性の概日リズムと時計発振系への関与
真田 佳門, 林 勇一郎, 原田 裕子, 岡野 俊行, 深田 吉孝
日本時間生物学会会誌: Journal of Chronobiology 5 ( 2 ) 52 - 52 1999.10
ハト脳脊髄液に含まれるメラトニン量の日周変動 : マイクロダイアリシス法を用いた解析
吉川 朋子, 飯郷 雅之, 足立 明人, 海老原 史樹文, 岡野 俊行, 深田 吉孝
日本時間生物学会会誌: Journal of Chronobiology 5 ( 2 ) 1999.10
サーカディアンクロック ニワトリ松果体における概日時計の光位相シフト経路の解析
岡野 俊行, 笠原 和起, 吉川 朋子, 山崎 一恭, 芳賀 達也, 深田 吉孝
生化学 71 ( 8 ) 662 - 662 1999.08
ニワトリ松果体MAPキナーゼ活性の概日リズムとその役割
真田 佳門, 林 勇一郎, 原田 裕子, 岡野 俊行, 深田 吉孝
生化学 71 ( 8 ) 904 - 904 1999.08
Immunocytochemical localization of visual pigments and HPLC analysis of retinal in the pineal, deep brain and skin of several species of anuran amphibians
K Okano, T Yoshikawa, T Okano, T Seki, A Masuda, Y Fukada, T Oishi
RECENT PROGRESS IN MOLECULAR AND COMPARATIVE ENDOCRINOLOGY 365 - 369 1999 [Refereed]
Doi M., Okano T., Fukada Y.
Zoological science 16 101 - 101 1999
Meta II intermediate of chicken pinopsin
Nakamura A, Kojima D, Imai H, Terakita A, Okano T, Shichida Y, Fukada Y
Seibutsu Butsuri 39 ( 0 ) 1999
時計細胞における概日時計の光リセット機構と時刻可視化の試み
笠原 和起, 広田 毅, 佐々木 桃子, 岡野 俊行, 深田 吉孝
バイオイメージング 7 ( 3 ) 163 - 164 1998.10
Effects of brefeldin A on melatonin production in chick pineal cells
Hirota T., Kagiwada S., Kasahara T., Okano T., Fukada Y., Murata M.
Biophysics 38 ( 2 ) S47 1998.09
Activation of chicken pineal transducin by light
Kasahara T., Okano T., Yoshikawa T, Matsushita A., Yamazaki K., Fukada Y.
Biophysics 38 ( 2 ) S83 1998.09
Photobleaching process of pinopsin : Is pinopsin a rod-type or a cone-type photoreceptive pigment?
Nakamura A, Kojima D, Imai H, Terakita A, Okano T, Shichida Y, Fukada Y
Biophysics 38 ( 2 ) 1998.09
Takanaka Y., Okano T., Fukada Y.
Zoological science 15 107 - 107 1998
Production of chicken pineal photoreceptor pinopsin in cultured cells
NAKAMURA A., KOJIMA D., OKANO T., FUKADA Y.
Biophysics 37 S222 1997.10
ハト脳深部の外側中隔に発現する光受容タンパク質の同定
岡野 俊行, 和田 恭高, 深田 吉孝, 足立 明人, 海老原 史樹文
日本時間生物学会会誌: Journal of Chronobiology 3 ( 2 ) 108 - 108 1997.10
ヒキガエルの脳深部に存在する光受容分子の同定
吉川 朋子, 岡野 俊行, 大石 正, 深田 吉孝
日本時間生物学会会誌: Journal of Chronobiology 3 ( 2 ) 58 - 58 1997.10
Photon-signal transducing G-protein in chicken pineal gland
KASAHARA T., OKANO T., YOSHIKAWA T., YAMAZAKI K., FUKADA Y.
Biophysics 37 S221 1997.10
松果体の光受容体ピノプシンの性状解析と時計情報伝達機構
岡野 俊行, 高中 陽子, 仲村 厚志, 山崎 一恭, 深田 吉孝, 蛭薙 観順
日本分子生物学会年会プログラム・講演要旨集 19 322 - 322 1996.08
MOLECULAR ANALYSIS OF BIOLOGICAL CLOCKS
Y FUKADA, T OKANO
SEIKAGAKU 67 ( 9 ) 1137 - 1142 1995.09
Book review, literature introduction, etc.
10.錐体視物質アオイドプシンのアミノ酸配列 : 脂溶性ビタミン総合研究委員会第244回会議研究発表要旨
吉澤 透, 桑田 治, 今元 泰, 岡野 俊行, 小亀 浩市, 小島 大輔, 松本 博樹, 深田 吉孝, 七田 芳則
ビタミン 65 ( 3 ) 138 - 138 1991.03
6.合成レチナールアナログを用いたアイオドプシンのレチナール結合部位の研究 : 脂溶性ビタミン総合研究委員会第240回会議研究発表要旨
吉沢 透, 深田 吉孝, 岡野 俊行, Liu R.S.H.
ビタミン 64 ( 7 ) 398 - 399 1990.07
ニワトリ網膜の色覚色素の抽出・精製とGTP結合タンパク質の活性化 : 脂溶性ビタミン総合研究委員会 : 第233回会議研究発表要旨
吉澤 透, 岡野 俊行, 深田 吉孝, Artamenov Igor D.
ビタミン 62 ( 12 ) 680 - 680 1988.12
光感受性遺伝子発現調節システム
岡野 俊行
Patent
New Investigator Award, American Society for Photobiology
2002
日本比較生理生化学会 吉田奨励賞
1995
Structure and function of light-driven magnetoreceptors for GPS in animals
Project Year :
月齢応答機構の解明に向けたモデル細胞の創出
Project Year :
Molecular machinery of lunar-synchronous spawning in the brain of a tropical fish
Project Year :
Development of control method for indoor lighting environment to maintain comfortable and healthy life rhythm
Project Year :
Development of a novel protein purification/regulation methodology by using a temperature-sensitive monoclonal antibody.
Project Year :
Physiological studies on the transduction system of tidal stimuli in the brain of teleost fish
Project Year :
Control of protein localization and activity using photoreceptors
Project Year :
脳に存在する生物時計のリアルタイム追跡とプローブ探索
脳内光受容と生物時計を支える分子基盤
脳に存在する生物時計細胞のリアルタイム追跡と光情報伝達機構
体内時計の光位相同調とメラトニン出力系の調節メカニズム
生物時計や光周性を支える脳内光受容の分子メカニズム
鳥類および哺乳類における概日時計の自己発振と光同調の分子メカニズム
脳内の時計細胞における概日リズム発振系と光入力系の分子解析
時刻情報の生成・制御を支える転写因子群の発現プログラム
Molecular, cellular and in vivo analyses of photoresponses and circadian rhythms in animals
時刻情報の生成・制御を支える転写因子群の発現プログラム
遺伝子導入動物から迫る概日時計の新規構成分子
時刻情報の生成・制御を支える転写因子群の発現プログラム
時刻情報の生成・制御を支える転写因子群の発現プログラム
A trial of gene-activity regulation by using photoreceptor proteins.
2019
Graduation Thesis B [Spring] [S Grade]
School of Advanced Science and Engineering
2022 spring semester
Laboratory C on Electrical Engineering and Bioscience [S Grade]
School of Advanced Science and Engineering
2022 fall semester
Laboratory C on Electrical Engineering and Bioscience
School of Advanced Science and Engineering
2022 fall semester
Frontiers of Electrical Engineering and Bioscience [S Grade]
School of Advanced Science and Engineering
2022 spring semester
Frontiers of Electrical Engineering and Bioscience
School of Advanced Science and Engineering
2022 spring semester
Current Topics in Biosciences [S Grade]
School of Advanced Science and Engineering
2022 fall semester
Seminar on Molecular and Cellular Biosciences D
Graduate School of Advanced Science and Engineering
2022 fall semester
Seminar on Molecular and Cellular Biosciences C
Graduate School of Advanced Science and Engineering
2022 spring semester
Seminar on Molecular and Cellular Biosciences B
Graduate School of Advanced Science and Engineering
2022 fall semester
Seminar on Molecular and Cellular Biosciences A
Graduate School of Advanced Science and Engineering
2022 spring semester
Research on Molecular and Cellular Biosciences
Graduate School of Advanced Science and Engineering
2022 full year
Master's Thesis (Department of Electrical Engineering and Bioscience)
Graduate School of Advanced Science and Engineering
2022 full year
Research on Molecular and Cellular Biosciences
Graduate School of Advanced Science and Engineering
2022 full year
Seminar on Molecular and Cellular Biosciences D
Graduate School of Advanced Science and Engineering
2022 fall semester
Seminar on Molecular and Cellular Biosciences C
Graduate School of Advanced Science and Engineering
2022 spring semester
Seminar on Molecular and Cellular Biosciences B
Graduate School of Advanced Science and Engineering
2022 fall semester
Seminar on Molecular and Cellular Biosciences A
Graduate School of Advanced Science and Engineering
2022 spring semester
Research on Molecular and Cellular Biosciences
Graduate School of Advanced Science and Engineering
2022 full year
Master's Thesis (Department of Electrical Engineering and Bioscience)
Graduate School of Advanced Science and Engineering
2022 full year
Advanced Environmental Physiology
Graduate School of Advanced Science and Engineering
2022 an intensive course(spring)