Education Background
-
-1997
Keio University Graduate School of Medicine
-
-1990
Keio University School of Medicine
Details of a Researcher
Updated on 2024/12/07
Keio University Graduate School of Medicine
Keio University School of Medicine
THE JAPAN SOCIETY OF HEPATOLOGY
日本分子生物学会
日本生化学会
糖尿病
糖・脂質代謝
肝臓病
ノックアウトマウス
低酸素応答・低酸素ストレス
Best Poster Award
2011.10 6th International Symposium on ALPD and Cirrhosis
Winner: 合田 亘人
高田賞 第30回アルコール医学生物学研究会
2010
上原記念生命科学財団 海外留学助成ポストドクトラルフェローシップ
2000
SDHAF1 confers metabolic resilience to aging hematopoietic stem cells by promoting mitochondrial ATP production.
Shintaro Watanuki, Hiroshi Kobayashi, Yuki Sugiura, Masamichi Yamamoto, Daiki Karigane, Kohei Shiroshita, Yuriko Sorimachi, Takayuki Morikawa, Shinya Fujita, Kotaro Shide, Miho Haraguchi, Shinpei Tamaki, Takumi Mikawa, Hiroshi Kondoh, Hiroyasu Nakano, Kenta Sumiyama, Go Nagamatsu, Nobuhito Goda, Shinichiro Okamoto, Ayako Nakamura-Ishizu, Kazuya Shimoda, Makoto Suematsu, Toshio Suda, Keiyo Takubo
Cell stem cell 2024.05 [International journal]
Mesenchymal loss of p53 alters stem cell capacity and models human soft tissue sarcoma traits.
Yuriko Sorimachi, Hiroshi Kobayashi, Yusuke Shiozawa, Shuhei Koide, Ryuichiro Nakato, Yukiko Shimizu, Tadashi Okamura, Katsuhiko Shirahige, Atsushi Iwama, Nobuhito Goda, Kaiyo Takubo, Keiyo Takubo
Stem cell reports 18 ( 5 ) 1211 - 1226 2023.04 [Refereed] [International journal]
Shintaro Watanuki, Hiroshi Kobayashi, Yuki Sugiura, Masamichi Yamamoto, Daiki Karigane, Kohei Shiroshita, Yuriko Sorimachi, Shuhei Koide, Motohiko Oshima, Akira Nishiyama, Koichi Murakami, Miho Haraguchi, Shinpei Tamaki, Takehiro Yamamoto, Tomohiro Yabushita, Yosuke Tanaka, Hiroaki Honda, Shinichiro Okamoto, Nobuhito Goda, Tomohiko Tamura, Ayako Nakamura-Ishizu, Makoto Suematsu, Atsushi Iwama, Toshio Suda, Keiyo Takubo
bioRxiv 2023.03
Koji Noguchi, Kyosuke Yokozeki, Yuko Tanaka, Yasuhiro Suzuki, Kazuki Nakajima, Takashi Nishimura, Nobuhito Goda
Genes to Cells 27 ( 2 ) 145 - 151 2022.02 [Refereed]
Authorship:Corresponding author
Epithelial cells remove precancerous cells by cell competition via MHC class I–LILRB3 interaction
Shiyu Ayukawa, Nagisa Kamoshita, Jun Nakayama, Ryohei Teramoto, Novalia Pishesha, Kenji Ohba, Nanami Sato, Kei Kozawa, Hikari Abe, Kentaro Semba, Nobuhito Goda, Yasuyuki Fujita, Takeshi Maruyama
Nature Immunology 22 ( 11 ) 1391 - 1402 2021.11 [Refereed] [International journal]
SLC15A4 mediates M1-prone metabolic shifts in macrophages and guards immune cells from metabolic stress.
Toshihiko Kobayashi, Dat Nguyen-Tien, Yuriko Sorimachi, Yuki Sugiura, Takehiro Suzuki, Hitomi Karyu, Shiho Shimabukuro-Demoto, Tatsuki Uemura, Tadashi Okamura, Tomohiko Taguchi, Kohjiro Ueki, Norihiro Kato, Nobuhito Goda, Naoshi Dohmae, Keiyo Takubo, Makoto Suematsu, Noriko Toyama-Sorimachi
Proceedings of the National Academy of Sciences of the United States of America 118 ( 33 ) 2021.08 [Refereed] [International journal]
p38α plays differential roles in hematopoietic stem cell activity dependent on aging contexts.
Yuriko Sorimachi, Daiki Karigane, Yukako Ootomo, Hiroshi Kobayashi, Takayuki Morikawa, Kinya Otsu, Yoshiaki Kubota, Shinichiro Okamoto, Nobuhito Goda, Keiyo Takubo
The Journal of biological chemistry 296 100563 - 100563 2021.03 [Refereed] [International journal]
In vivo O2 imaging in hepatic tissues by phosphorescence lifetime imaging microscopy using Ir(III) complexes as intracellular probes.
Kiichi Mizukami, Ayaka Katano, Shuichi Shiozaki, Toshitada Yoshihara, Nobuhito Goda, Seiji Tobita
Scientific reports 10 ( 1 ) 21053 - 21053 2020.12 [Refereed] [International journal]
ZAK Inhibitor PLX4720 Promotes Extrusion of Transformed Cells via Cell Competition.
Takeshi Maruyama, Ayana Sasaki, Sayuri Iijima, Shiyu Ayukawa, Nobuhito Goda, Keisuke Tazuru, Norikazu Hashimoto, Takashi Hayashi, Kei Kozawa, Nanami Sato, Susumu Ishikawa, Tomoko Morita, Yasuyuki Fujita
iScience 23 ( 7 ) 101327 - 101327 2020.07 [Refereed] [International journal]
Adrenal cortex hypoxia modulates aldosterone production in heart failure.
Kaoru Yamashita, Kentaro Ito, Jin Endo, Tomohiro Matsuhashi, Yoshinori Katsumata, Tsunehisa Yamamoto, Kohsuke Shirakawa, Sarasa Isobe, Masaharu Kataoka, Naohiro Yoshida, Shinichi Goto, Hidenori Moriyama, Hiroki Kitakata, Fumiko Mitani, Keiichi Fukuda, Nobuhito Goda, Atsuhiro Ichihara, Motoaki Sano
Biochemical and biophysical research communications 524 ( 1 ) 184 - 189 2020.03 [Refereed] [International journal]
Generation of Rat Monoclonal Antibodies Specific for Human Stromal Cell-Derived Factor-2.
Masako Tanaka, Masayuki Shiota, Masaru Koyama, Jun Nakayama, Masakazu Yashiro, Kentaro Semba, Nobuhito Goda
Monoclonal antibodies in immunodiagnosis and immunotherapy 39 ( 1 ) 23 - 26 2020.02 [Refereed] [International journal]
Metabolic adaptation to glycolysis is a basic defense mechanism of macrophages for Mycobacterium tuberculosis infection.
Mayuko Osada-Oka, Nobuhito Goda, Hiroyuki Saiga, Masahiro Yamamoto, Kiyoshi Takeda, Yuriko Ozeki, Takehiro Yamaguchi, Tomoyoshi Soga, Yu Tateishi, Katsuyuki Miura, Daisuke Okuzaki, Kazuo Kobayashi, Sohkichi Matsumoto
International immunology 31 ( 12 ) 781 - 793 2019.11 [Refereed] [International journal]
Pyruvate dehydrogenase activation precedes the down-regulation of fatty acid oxidation in monocrotaline-induced myocardial toxicity in mice.
Gaku Nakai, Daisuke Shimura, Ken Uesugi, Ichige Kajimura, Qibin Jiao, Yoichiro Kusakari, Tomoyoshi Soga, Nobuhito Goda, Susumu Minamisawa
Heart and vessels 34 ( 3 ) 545 - 555 2019.03 [Refereed] [Domestic journal]
Differential expression of Lutheran/BCAM regulates biliary tissue remodeling in ductular reaction during liver regeneration.
Yasushi Miura, Satoshi Matsui, Naoko Miyata, Kenichi Harada, Yamato Kikkawa, Masaki Ohmuraya, Kimi Araki, Shinya Tsurusaki, Hitoshi Okochi, Nobuhito Goda, Atsushi Miyajima, Minoru Tanaka
eLife 7 2018.07 [Refereed] [International journal]
Effects of aging on serum levels of lipid molecular species as determined by lipidomics analysis in Japanese men and women.
Noriaki Kawanishi, Yuki Kato, Kyosuke Yokozeki, Shuji Sawada, Ryota Sakurai, Yoshinori Fujiwara, Shoji Shinkai, Nobuhito Goda, Katsuhiko Suzuki
Lipids in health and disease 17 ( 1 ) 135 - 135 2018.06 [Refereed] [International journal]
Loss of hypoxia inducible factor-1α aggravates γδ T-cell-mediated inflammation during acetaminophen-induced liver injury.
Tomohiro Suzuki, Shoko Minagawa, Takashi Yamazaki, Takatomo Arai, Mai Kanai, Satoko Shinjo, Nobuhito Goda
Hepatology communications 2 ( 5 ) 571 - 581 2018.05 [Refereed] [International journal]
Authorship:Corresponding author
Disruption of the mitochondria-associated ER membrane (MAM) plays a central role in palmitic acid-induced insulin resistance.
Satoko Shinjo, Shuying Jiang, Masaaki Nameta, Tomohiro Suzuki, Mai Kanai, Yuta Nomura, Nobuhito Goda
Experimental cell research 359 ( 1 ) 86 - 93 2017.10 [Refereed] [International journal]
Authorship:Last author
Type I neuregulin1α is a novel local mediator to suppress hepatic gluconeogenesis in mice.
Takatomo Arai, Yumika Ono, Yujiro Arimura, Keimon Sayama, Tomohiro Suzuki, Satoko Shinjo, Mai Kanai, Shin-Ichi Abe, Kentaro Semba, Nobuhito Goda
Scientific reports 7 42959 - 42959 2017.02 [Refereed] [International journal]
Authorship:Corresponding author
HIF-1α in Myeloid Cells Promotes Adipose Tissue Remodeling Toward Insulin Resistance.
Akiko Takikawa, Arshad Mahmood, Allah Nawaz, Tomonobu Kado, Keisuke Okabe, Seiji Yamamoto, Aminuddin Aminuddin, Satoko Senda, Koichi Tsuneyama, Masashi Ikutani, Yasuharu Watanabe, Yoshiko Igarashi, Yoshinori Nagai, Kiyoshi Takatsu, Keiichi Koizumi, Johji Imura, Nobuhito Goda, Masakiyo Sasahara, Michihiro Matsumoto, Kumiko Saeki, Takashi Nakagawa, Shiho Fujisaka, Isao Usui, Kazuyuki Tobe
Diabetes 65 ( 12 ) 3649 - 3659 2016.12 [Refereed] [International journal]
Index markers of chronic fatigue syndrome with dysfunction of TCA and urea cycles.
Emi Yamano, Masahiro Sugimoto, Akiyoshi Hirayama, Satoshi Kume, Masanori Yamato, Guanghua Jin, Seiki Tajima, Nobuhito Goda, Kazuhiro Iwai, Sanae Fukuda, Kouzi Yamaguti, Hirohiko Kuratsune, Tomoyoshi Soga, Yasuyoshi Watanabe, Yosky Kataoka
Scientific reports 6 34990 - 34990 2016.10 [Refereed] [International journal]
Lutheranは肝幹/前駆細胞の性状を制御する機能性マーカーである
三浦 泰史, 田中 稔, 吉川 大和, 合田 亘人, 宮島 篤
日本生化学会大会プログラム・講演要旨集 89回 [2P - 257] 2016.09
p38α Activates Purine Metabolism to Initiate Hematopoietic Stem/Progenitor Cell Cycling in Response to Stress.
Daiki Karigane, Hiroshi Kobayashi, Takayuki Morikawa, Yukako Ootomo, Mashito Sakai, Go Nagamatsu, Yoshiaki Kubota, Nobuhito Goda, Michihiro Matsumoto, Emi K Nishimura, Tomoyoshi Soga, Kinya Otsu, Makoto Suematsu, Shinichiro Okamoto, Toshio Suda, Keiyo Takubo
Cell stem cell 19 ( 2 ) 192 - 204 2016.08 [Refereed] [International journal]
The H3K9 methyltransferase Setdb1 regulates TLR4-mediated inflammatory responses in macrophages.
Rumi Hachiya, Takuya Shiihashi, Ibuki Shirakawa, Yorihiro Iwasaki, Yoshihiro Matsumura, Yumiko Oishi, Yukiteru Nakayama, Yoshihiro Miyamoto, Ichiro Manabe, Kozue Ochi, Miyako Tanaka, Nobuhito Goda, Juro Sakai, Takayoshi Suganami, Yoshihiro Ogawa
Scientific reports 6 28845 - 28845 2016.06 [Refereed] [International journal]
HIF-1α-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity.
Hiroaki Semba, Norihiko Takeda, Takayuki Isagawa, Yuki Sugiura, Kurara Honda, Masaki Wake, Hidenobu Miyazawa, Yoshifumi Yamaguchi, Masayuki Miura, Dana M R Jenkins, Hyunsung Choi, Jung-Whan Kim, Masataka Asagiri, Andrew S Cowburn, Hajime Abe, Katsura Soma, Katsuhiro Koyama, Manami Katoh, Keimon Sayama, Nobuhito Goda, Randall S Johnson, Ichiro Manabe, Ryozo Nagai, Issei Komuro
Nature communications 7 11635 - 11635 2016.05 [Refereed] [International journal]
右心不全モデルラットにおける肝線維化因子の検討(Low cardiac output leads hepatic fibrosis in right heart failure model rats)
Fujimoto Yoshitaka, Urashima Takashi, Ito Reiji, Kajimura Ichige, Akaike Toru, Kusakari Yoichiro, Goda Nobuhito, Minamisawa Susumu
The Journal of Physiological Sciences 66 ( Suppl.1 ) S163 - S163 2016.03
Heterozygous deletion of sarcolipin maintains normal cardiac function.
Daisuke Shimura, Yoichiro Kusakari, Tetsuo Sasano, Yasuhiro Nakashima, Gaku Nakai, Qibin Jiao, Meihua Jin, Tomohiro Yokota, Yoshihiro Ishikawa, Atsushi Nakano, Nobuhito Goda, Susumu Minamisawa
American journal of physiology. Heart and circulatory physiology 310 ( 1 ) H92-103 - H103 2016.01 [Refereed] [International journal]
Low Cardiac Output Leads Hepatic Fibrosis in Right Heart Failure Model Rats.
Yoshitaka Fujimoto, Takashi Urashima, Daisuke Shimura, Reiji Ito, Sadataka Kawachi, Ichige Kajimura, Toru Akaike, Yoichiro Kusakari, Masako Fujiwara, Kiyoshi Ogawa, Nobuhito Goda, Hiroyuki Ida, Susumu Minamisawa
PloS one 11 ( 2 ) e0148666 2016 [Refereed] [International journal]
Innate Response to Human Cancer Cells with or without IL-2 Receptor Common γ-Chain Function in NOD Background Mice Lacking Adaptive Immunity.
Chiyoko Nishime, Kenji Kawai, Takehiro Yamamoto, Ikumi Katano, Makoto Monnai, Nobuhito Goda, Tomoko Mizushima, Hiroshi Suemizu, Masato Nakamura, Mitsuru Murata, Makoto Suematsu, Masatoshi Wakui
Journal of immunology (Baltimore, Md. : 1950) 195 ( 4 ) 1883 - 90 2015.08 [Refereed] [International journal]
Potential Biomarkers of Fatigue Identified by Plasma Metabolome Analysis in Rats
Satoshi Kume, Masanori Yamato, Yasuhisa Tamura, Guanghua Jin, Masayuki Nakano, Yukiharu Miyashige, Asami Eguchi, Yoshiyuki Ogata, Nobuhito Goda, Kazuhiro Iwai, Emi Yamano, Yasuyoshi Watanabe, Tomoyoshi Soga, Yosky Kataoka
PLOS ONE 10 ( 3 ) e0120106 2015.03 [Refereed]
WITHDRAWN: Loss of hepatic HIF-1α accelerates lipid accumulation by inhibiting peroxisomal fatty acid oxidation in nonalcoholic fatty liver disease.
Takatomo Arai, Yuki Kato, Kenji Ishimoto, Mai Kanai, Satoko Shinjo, Keimon Sayama, Tomohiro Suzuki, Takefumi Doi, Randall S Johnson, Makoto Suematsu, Nobuhito Goda
Journal of hepatology 2015.02 [International journal]
ヒストンメチル化酵素によるマクロファージの炎症抑制機構の解明
椎橋 卓哉, 蜂屋 瑠見, 菅波 孝祥, 白川 伊吹, 合田 亘人, 小川 佳宏
肥満研究 20 ( Suppl. ) 179 - 179 2014.10
Transcription Profiles of the Ductus Arteriosus in Brown-Norway Rats With Irregular Elastic Fiber Formation
Yi-Ting Hsieh, Norika Mengchia Liu, Eriko Ohmori, Tomohiro Yokota, Ichige Kajimura, Toru Akaike, Toshio Ohshima, Nobuhito Goda, Susumu Minamisawa
CIRCULATION JOURNAL 78 ( 5 ) 1224 - U252 2014.05 [Refereed]
ニワトリ動脈管において内膜クッションと弾性線維形成不全が明らかになった(Intimal Cushion and Elastic Fibers Degradation were shown Formation Were Less Prominent in the Chicken Ductus Arteriosus)
Omori Eriko, Akaike Toru, Kajimura Ichige, Goda Nobuhito, Minamisawa Susumu
The Journal of Physiological Sciences 64 ( Suppl.1 ) S183 - S183 2014.03
Metabolomic profiling analysis reveals chamber-dependent metabolite patterns in the mouse heart
Daisuke Shimura, Gaku Nakai, Qibin Jiao, Kota Osanai, Kasumi Kashikura, Keiko Endo, Tomoyoshi Soga, Nobuhito Goda, Susumu Minamisawa
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 305 ( 4 ) H494 - H505 2013.08 [Refereed]
Adipose tissue hypoxia induces inflammatory M1 polarity of macrophages in an HIF-1α-dependent and HIF-1α-independent manner in obese mice
S. Fujisaka, I. Usui, M. Ikutani, A. Aminuddin, A. Takikawa, K. Tsuneyama, A. Mahmood, N. Goda, Y. Nagai, K. Takatsu, K. Tobe
Diabetologia 56 ( 6 ) 1403 - 1412 2013.06 [Refereed]
Adipose Tissue Hypoxia Induces Inflammatory M1 Polarity of Macrophages in HIF-1 alpha-Dependent and HIF-1 alpha-Independent Manners in Obese Mice
Fujisaka Shiho, Usui Isao, Ikutani Masashi, Aminuddin Aminuddin, Takikawa Akiko, Tsuneyama Koichi, Mahmood Arshad, Goda Nobuhito, Nagai Yoshinori, Takatsu Kiyoshi, Tobe Kazuyuki
Diabetologia 56 1403 - 1412 2013.06 [Refereed]
Regulation of Glycolysis by Pdk Functions as a Metabolic Checkpoint for Cell Cycle Quiescence in Hematopoietic Stem Cells
Keiyo Takubo, Go Nagamatsu, Chiharu I. Kobayashi, Ayako Nakamura-Ishizu, Hiroshi Kobayashi, Eiji Ikeda, Nobuhito Goda, Yasmeen Rahimi, Randall S. Johnson, Tomoyoshi Soga, Atsushi Hirao, Makoto Suematsu, Toshio Suda
CELL STEM CELL 12 ( 1 ) 49 - 61 2013.01 [Refereed]
HIF-1 in T cells ameliorated dextran sodium sulfate-induced murine colitis
Masaaki Higashiyama, Ryota Hokari, Hideaki Hozumi, Chie Kurihara, Toshihide Ueda, Chikako Watanabe, Kengo Tomita, Mitsuyasu Nakamura, Shunsuke Komoto, Yoshikiyo Okada, Atsushi Kawaguchi, Shigeaki Nagao, Makoto Suematsu, Nobuhito Goda, Soichiro Miura
JOURNAL OF LEUKOCYTE BIOLOGY 91 ( 6 ) 901 - 909 2012.06 [Refereed]
A role for endothelial cells in promoting the maturation of astrocytes through the apelin/APJ system in mice
Susumu Sakimoto, Hiroyasu Kidoya, Hisamichi Naito, Motohiro Kamei, Hirokazu Sakaguchi, Nobuhito Goda, Akiyoshi Fukamizu, Kohji Nishida, Nobuyuki Takakura
DEVELOPMENT 139 ( 7 ) 1327 - 1335 2012.04 [Refereed]
The formation of an angiogenic astrocyte template is regulated by the neuroretina in a HIF-1-dependent manner
Ayako Nakamura-Ishizu, Toshihide Kurihara, Yuji Okuno, Yoko Ozawa, Kazuo Kishi, Nobuhito Goda, Kazuo Tsubota, Hideyuki Okano, Toshio Suda, Yoshiaki Kubota
DEVELOPMENTAL BIOLOGY 363 ( 1 ) 106 - 114 2012.03 [Refereed]
HIF-1 alpha induction suppresses excessive lipid accumulation in alcoholic fatty liver in mice
Yasumasa Nishiyama, Nobuhito Goda, Mai Kanai, Daisuke Niwa, Kota Osanai, Yu Yamamoto, Nanami Senoo-Matsuda, Randall S. Johnson, Soichiro Miura, Yasuaki Kabe, Makoto Suematsu
JOURNAL OF HEPATOLOGY 56 ( 2 ) 441 - 447 2012.02 [Refereed]
Authorship:Corresponding author
HIF-mediated regulation of carbohydrate and lipid metabolisms in the liver
Nobuhito Goda
Seikagaku 84 ( 11 ) 942 - 947 2012 [Refereed] [Invited]
Disruption of HIF-1 alpha in hepatocytes impairs glucose metabolism in diet-induced obesity mice
Daigo Ochiai, Nobuhito Goda, Takako Hishiki, Mai Kanai, Nanami Senoo-Matsuda, Tomoyoshi Soga, Randall S. Johnson, Yasunori Yoshimura, Makoto Suematsu
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 415 ( 3 ) 445 - 449 2011.11 [Refereed]
Authorship:Corresponding author
アルコール性脂肪肝における低酸素応答性転写制御因子HIF-1の機能解析
合田 亘人, 西山 靖将, 末松 誠
アルコールと医学生物学 30 7 - 10 2011.04
T細胞特異的HIF-1欠損による消化管免疫の変化
東山 正明, 穂苅 量太, 八月朔日 秀明, 上田 俊秀, 栗原 千枝, 冨田 謙吾, 中村 光康, 岡田 義清, 川口 淳, 永尾 重昭, 三浦 総一郎, 合田 亘人
消化器と免疫 ( 47 ) 58 - 61 2011.03
HIF-1を介するDEC1誘導は、エタノールに慢性曝露したマウスの肝臓への脂質過剰蓄積を抑制する(HlF-1-mediated DEC1 induction inhibits excessive lipid accumulation in liver of mice chronically exposed to ethanol)
合田 亘人, 西山 靖将, 末松 誠
日本生化学会大会・日本分子生物学会年会合同大会講演要旨集 83回・33回 3P - 1108 2010.12
Regulation of the HIF-1 alpha Level Is Essential for Hematopoietic Stem Cells
Keiyo Takubo, Nobuhito Goda, Wakako Yamada, Hirono Iriuchishima, Eiji Ikeda, Yoshiaki Kubota, Haruko Shima, Randall S. Johnson, Atsushi Hirao, Makoto Suematsu, Toshio Suda
CELL STEM CELL 7 ( 3 ) 391 - 402 2010.09 [Refereed]
von Hippel-Lindau protein regulates transition from the fetal to the adult circulatory system in retina
Toshihide Kurihara, Yoshiaki Kubota, Yoko Ozawa, Keiyo Takubo, Kousuke Noda, M. Celeste Simon, Randall S. Johnson, Makoto Suematsu, Kazuo Tsubota, Susumu Ishida, Nobuhito Goda, Toshio Suda, Hideyuki Okano
DEVELOPMENT 137 ( 9 ) 1563 - 1571 2010.05 [Refereed]
Fenofibrate, a Peroxisome Proliferator-Activated Receptor alpha Agonist, Improves Hepatic Microcirculatory Patency and Oxygen Availability in a High-Fat-Diet-Induced Fatty Liver in Mice
Kazunari Kondo, Tadao Sugioka, Kosuke Tsukada, Michiyoshi Aizawa, Masayuki Takizawa, Kenji Shimizu, Masaya Morimoto, Makoto Suematsu, Nobuhito Goda
OXYGEN TRANSPORT TO TISSUE XXXI 662 77 - 82 2010 [Refereed]
HIF-1 alpha is necessary to support gluconeogenesis during liver regeneration
Toshihide Tajima, Nobuhito Goda, Natsuko Fujiki, Takako Hishiki, Yasumasa Nishiyama, Nanami Senoo-Matsuda, Motohide Shimazu, Tomoyoshi Soga, Yasunori Yoshimura, Randall S. Johnson, Makoto Suematsu
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 387 ( 4 ) 789 - 794 2009.10 [Refereed]
Authorship:Corresponding author
エタノール誘導性脂肪肝形成におけるHIF-1αの役割について
西山 靖将, 末松 誠, 合田 亘人
日本生化学会大会プログラム・講演要旨集 82回 3P - 758 2009.09
Cystathionine beta-Synthase as a Carbon Monoxide-Sensitive Regulator of Bile Excretion
Tsunehiro Shintani, Takuya Iwabuchi, Tomoyoshi Soga, Yuichiro Kato, Takehiro Yamamoto, Naoharu Takano, Takako Hishiki, Yuki Ueno, Satsuki Ikeda, Tadayuki Sakuragawa, Kazuo Ishikawa, Nobuhito Goda, Yuko Kitagawa, Mayumi Kajjimura, Kenji Matsumoto, Makoto Suematsu
HEPATOLOGY 49 ( 1 ) 141 - 150 2009.01 [Refereed]
メタボロミクスが解き明かす生命のシステム 低酸素感受性転写因子HIF-1肝細胞特異的ノックアウトマウスにおける肝再生時の系統的代謝異常解析(HlF-1 is necessary for coordinated control of gluconeogenesis during liver regeneration)
末松 誠, 田島 敏秀, ジョンソン・ランダル, 合田 亘人
日本生化学会大会・日本分子生物学会年会合同大会講演要旨集 81回・31回 3S2 - 3 2008.11
HIF-1 is not a critical determinant for metabolic zonation in liver acinus
Goda Nobuhito, Ochiai Daigo, Fujiki Natsuko, Johnson Randall S, Suematsu Makoto
FASEB JOURNAL 22 2008.04 [Refereed]
Erythrocytes with T-state-stabilized hemoglobin as a therapeutic tool for postischemic liver dysfunction
Kazuhiro Suganuma, Kosuke Tsukada, Misato Kashiba, Antonio Tsuneshige, Toshiharu Furukawa, Tetsuro Kubota, Nobuhito Goda, Masaki Kitajima, Takashi Yonetani, Makoto Suematsu
ANTIOXIDANTS & REDOX SIGNALING 8 ( 9-10 ) 1847 - 1855 2006.09 [Refereed]
Carbon monoxide from heme oxygenase-2 is a tonic regulator against NO-dependent vasodilatation in the adult rat cerebral microcirculation
M Ishikawa, M Kajimura, T Adachi, K Maruyama, N Makino, N Goda, T Yamaguchi, E Sekizuka, M Suematsu
CIRCULATION RESEARCH 97 ( 12 ) E104 - E114 2005.12 [Refereed]
Carbon monoxide as a guardian against hepatobiliary dysfunction
M Suematsu, K Tsukada, T Tajima, T Yamamoto, D Ochiai, H Watanabe, Y Yoshimura, N Goda
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 29 ( 11 ) 134S - 139S 2005.11 [Refereed]
Hydrogen sulfide as an endogenous modulator of biliary bicarbonate excretion in the rat liver
K Fujii, T Sakuragawa, M Kashiba, Y Sugiura, M Kondo, K Maruyama, N Goda, Y Nimura, M Suematsu
ANTIOXIDANTS & REDOX SIGNALING 7 ( 5-6 ) 788 - 794 2005.05 [Refereed]
HIF-1 in cell cycle regulation, apoptosis, and tumor progression
N Goda, SJ Dozier, RS Johnson
ANTIOXIDANTS & REDOX SIGNALING 5 ( 4 ) 467 - 473 2003.08 [Refereed]
Hypoxia-inducible factor 1 alpha is essential for cell cycle arrest during hypoxia
N Goda, HE Ryan, B Khadivi, W McNulty, RC Rickert, RS Johnson
MOLECULAR AND CELLULAR BIOLOGY 23 ( 1 ) 359 - 369 2003.01 [Refereed]
Stabilization of mast cells by heme oxygenase-1: an anti-inflammatory role
R Takamiya, M Murakami, M Kajimura, N Goda, N Makino, Y Takamiya, T Yamaguchi, Y Ishimura, N Hozumi, M Suematsu
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 283 ( 3 ) H861 - H870 2002.09 [Refereed]
Stabilization of mast cells by heme oxygenase-1: an anti-inflammatory role
R Takamiya, M Murakami, M Kajimura, N Goda, N Makino, Y Takamiya, T Yamaguchi, Y Ishimura, N Hozumi, M Suematsu
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 283 ( 3 ) H861 - H870 2002.09 [Refereed]
誘導型ヘムオキシゲナーゼの生物活性の網羅的解析
近藤 三恵子, 加柴 美里, 牧野 信也, 合田 亘人, 和田 洋一郎, 興梠 貴英, 児玉 龍彦, 末松 誠
生化学 74 ( 8 ) 1074 - 1074 2002.08
Altered expression of heme oxygenase-1 in the livers of patients with portal hypertensive diseases
N Makino, M Suematsu, Y Sugiura, H Morikawa, S Shiomi, N Goda, T Sano, Y Nimura, K Sugimachi, Y Ishimura
HEPATOLOGY 33 ( 1 ) 32 - 42 2001.01 [Refereed]
Cloning and characterization of the promoter of murine cytohesin-1 gene
N Goda, A Tanoue, S Kikuchi, G Tsujimoto
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION 1493 ( 1-2 ) 195 - 199 2000.09 [Refereed]
Structure and sequence of the mouse V1a and V1b vasopressin receptor genes
S Kikuchi, A Tanoue, N Goda, N Matsuo, G Tsujimoto
JAPANESE JOURNAL OF PHARMACOLOGY 81 ( 4 ) 388 - 392 1999.12 [Refereed]
Characterization of the mouse alpha 1D-adrenergic receptor gene
K Arai, A Tanoue, N Goda, M Takeda, K Takahashi, G Tsujimoto
JAPANESE JOURNAL OF PHARMACOLOGY 81 ( 3 ) 271 - 278 1999.11 [Refereed]
Y Wakabayaski, R Takamiya, A Mizuki, T Kyokane, N Goda, T Yamaguchi, S Takeoka, E Tsuchida, M Suematsu, Y Ishimura
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 277 ( 5 ) G1088 - G1096 1999.11 [Refereed]
特発性門脈圧亢進症例におけるheme oxygenase-1発現異常
牧野 信也, 末松 誠, 合田 亘人, 石村 巽
生化学 71 ( 8 ) 1000 - 1000 1999.08
K Ohmi, H Shinoura, Y Nakayama, N Goda, G Tsujimoto
BRITISH JOURNAL OF PHARMACOLOGY 127 ( 3 ) 756 - 762 1999.06 [Refereed]
N Morikawa, M Suematsu, T Kyokane, N Goda, Y Kumamoto, T Okitsu, Y Ishimura, M Kitajima
HEPATOLOGY 28 ( 5 ) 1289 - 1299 1998.11 [Refereed]
ヒト肝臓及び脾臓におけるHO-1発現の免疫組織化学的検討
牧野 信也, 杉浦 芳章, 若林 良之, 合田 亘人, 末松 誠, 石村 巽
生化学 70 ( 8 ) 909 - 909 1998.08
ヘムオキシゲナーゼアイソザイムの細胞内局在部位の同定
若林 良之, 末松 誠, 内藤 眞, 合田 亘人, 石村 巽
生化学 70 ( 8 ) 1072 - 1072 1998.08
Carbon monoxide as a regulator of bile canalicular contractility in cultured rat hepatocytes
Y Shinoda, M Suematsu, Y Wakabayashi, T Suzuki, N Goda, S Saito, T Yamaguchi, Y Ishimura
HEPATOLOGY 28 ( 2 ) 286 - 295 1998.08 [Refereed]
Distribution of heme oxygenase isoforms in rat liver characterized by novel monoclonal antibodies
N Goda, M Naito, T Tamatani, Y Ishimura, M Suematsu
FASEB JOURNAL 12 ( 5 ) A1001 - A1001 1998.03 [Refereed]
R Takamiya, S Hayashi, N Goda, Y Wakabayashi, M Kitajima, T Tamatani, S Tojo, Y Ishimura, M Suematsu
FASEB JOURNAL 12 ( 5 ) A806 - A806 1998.03 [Refereed]
N Goda, K Suzuki, M Naito, S Takeoka, E Tsuchida, T Tametani, M Suematsu
JOURNAL OF CLINICAL INVESTIGATION 101 ( 3 ) 604 - 612 1998.02 [Refereed]
The heme oxygenase system in liver microcirculation: A key mechanism for hemoglobin degradation
M Suematsu, Y Wakabayashi, N Goda, S Takeoka, E Tsuchida, Y Ishimura
BLOOD SUBSTITUTES PRESENT AND FUTURE PERSPECTIVES 241 - 249 1998 [Refereed]
Ito cells: A putative cellular component responsible for carbon monoxide-mediated microvascular relaxation in the rat liver
Y Wakabayashi, S Kashiwagi, N Goda, Y Ishimura, M Suematsu
OXYGEN HOMEOSTASIS AND ITS DYNAMICS 1 469 - 472 1998 [Refereed]
An antioxidant role of nitric oxide in modulation of oxidative stress in human placental trophoblastic cells
N Goda, M Natori, M Suematsu, K Kiyokawa, Y Ishimura, Y Yoshimura, S Nozawa
OXYGEN HOMEOSTASIS AND ITS DYNAMICS 1 557 - 561 1998 [Refereed]
M Irokawa, M Nishinaga, U Ikeda, Y Shinoda, M Suematsu, N Gouda, Y Ishimura, K Shimada
ATHEROSCLEROSIS 135 ( 1 ) 9 - 17 1997.11 [Refereed]
末松 誠, 若林 良之, 武岡 真司, 合田 亘人, 土田 英俊, 石村 巽
G.I.Research 5 ( 5 ) 625 - 625 1997.10
T Sano, M Shiomi, Y Wakabayashi, Y Shinoda, N Goda, T Yamaguchi, Y Nimura, Y Ishimura, M Suematsu
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 272 ( 5 ) G1268 - G1275 1997.05 [Refereed]
N Goda, M Suematsu, M Mukai, K Kiyokawa, M Natori, S Nozawa, Y Ishimura
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 271 ( 5 ) H1893 - H1899 1996.11 [Refereed]
血管内皮細胞と動脈硬化・血栓 NOと内皮-好中球相互反応
若林 良之, 末松 誠, 合田 亘人
現代医療 28 ( 3 ) 761 - 767 1996.03
Heme oxygenase-CO pathwayによる毛細胆管収縮調節機構
篠田 雄一, 末松 誠, 合田 亘人
Cyto-protection & biology 13 59 - 60 1995.12
CARBON-MONOXIDE - AN ENDOGENOUS MODULATOR OF SINUSOIDAL TONE IN THE PERFUSED-RAT-LIVER
M SUEMATSU, N GODA, T SANO, S KASHIWAGI, T EGAWA, Y SHINODA, Y ISHIMURA
JOURNAL OF CLINICAL INVESTIGATION 96 ( 5 ) 2431 - 2437 1995.11 [Refereed]
臓器微小循環における内皮細胞-好中球間相互反応
末松 誠, 飯郷 裕, 合田 亘人
Surgery Frontier 2 ( 2 ) 149 - 154 1995.06
消化器疾患と活性酸素・フリーラジカル Digital Microfluorographyを用いた生体内酸素ストレスの画像解析法 低分子モノオキシドの生理作用
末松 誠, 合田 亘人, 石村 巽
臨床消化器内科 10 ( 6 ) 739 - 744 1995.05
CARBON-MONOXIDE AS AN ENDOGENOUS MODULATOR OF HEPATIC VASCULAR PERFUSION
M SUEMATSU, S KASHIWAGI, T SANO, N GODA, Y SHINODA, Y ISHIMURA
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 205 ( 2 ) 1333 - 1337 1994.12 [Refereed]
血管障害と接着分子 白血球と血管内皮細胞の相互作用 in vivo系
末松 誠, 合田 亘人, 飯郷 裕
現代医療 26 ( 9 ) 3109 - 3113 1994.09
低酸素感知・応答機構と疾患
合田亘人( Part: Sole author)
細胞 2022.03
生体の低酸素感知とその制御機構
前田 純江, 合田 亘人( Part: Joint author)
透析療法ネクストXXⅦ 2021.10 ISBN: 9784865174397
HIFs、PHDsと肝疾患
林絵莉子, 合田亘人( Part: Joint author)
医学のあゆみ 2020.07
低酸素ストレス応答の疾患生物学
合田亘人( Part: Sole author)
細胞 2013.07
HIFを介した防御機構:低酸素ストレス下のエネルギー代謝制御
合田亘人, 加藤早由華( Part: Joint author)
医学のあゆみ 2013.01
肝疾患とHIFを介した低酸素応答
合田亘人, 長内康太( Part: Joint author)
血管医学 2012.11
低酸素シグナリング -HIFシグナリング-
合田亘人( Part: Sole author)
イラストで徹底理解するシグナル伝達キーワード事典 2012.08
HIFが制御するエネルギー代謝-制御メカニズムとその破綻に起因する疾患-
合田亘人, 鈴木智大, 金井麻衣( Part: Joint author)
実験医学 2012.05
実験医学2012年5月号 VOL.30No.8〜代謝,発生,免疫で動き出す 低酸素応答システム
中山恒, 合田亘人( Part: Joint editor)
羊土社 2012.04 ISBN: 4758100837
低酸素転写制御因子とSDB
合田亘人, 鈴木智大( Part: Joint author)
呼吸器NEWS&VIEW 2012
「特集」代謝,発生,免疫で動き出す低酸素応答システム
中山, 恒, 合田, 亘人
羊土社 2012 ISBN: 9784758100830
肝細胞の不均一性と肝代謝制御
合田 亘人, 金井 麻衣( Part: Joint author)
実験医学 2011.08
低酸素のバイオイメージング : Hypoxia Inducible Factor の酸素代謝における役割
塚田 孝祐, 合田 亘人, 南谷 晴之, 末松 誠( Part: Joint author)
バイオイメージング 2006.10
肝・消化管と低酸素
合田 亘人, 槌谷夏子, 山本雄広( Part: Joint author)
炎症と免疫 2005.06
新規ヘパトカインによる代償性膵島肥大を介した血糖調節機構の解明
合田 亘人
第95回日本生化学会
Presentation date: 2022.11
代償性膵島肥大にかかわるヘパトカイン受容体の同定とその機能解析
合田 亘人
第29回肝細胞研究会
Presentation date: 2022.08
肝臓と膵臓を繋ぐ新規ヘパトカインの探索とその機能解析
合田 亘人 [Invited]
第7回肝臓と糖尿病・代謝研究会
Presentation date: 2021.05
2型糖尿病で肝臓から分泌される Hepatokine X は膵島肥大を誘導することで 血糖調節にかかわっている
合田 亘人, 林 絵莉子, 新井 理智
第27回肝細胞研究会
Presentation date: 2020.12
低酸素応答の疾患生物学
合田 亘人 [Invited]
第88回日本医科大学医学会総会
Presentation date: 2020.09
HIF-PHDを介した低酸素感知・応答システムの制御機構
合田 亘人 [Invited]
第63回日本腎臓学会
Presentation date: 2020.08
Hepatic Gpnmb improves systemic glucose tolerance in type II diabetic mice
Nobuhito Goda
Liver, Biology, Diseases & Cance
Presentation date: 2019.12
肝臓の代謝・炎症疾患におけるHIF1の病態抑制機構
合田 亘人 [Invited]
第72回日本酸化ストレス学会
Presentation date: 2019.06
自然免疫様T細胞のHIF-1による急性炎症制御機構の解明
合田 亘人
第91回日本生化学会
Presentation date: 2018.09
新しい糖新生調節因子の探索とその機能解析
合田 亘人 [Invited]
第5回肝臓と糖尿病・代謝研究会
Presentation date: 2018.07
Pathological role of HIF-1 in the liver
GODA Nobuhito [Invited]
Hypoxia Research Meeting 2018
Presentation date: 2018.07
Pathological role of HIF-1 in the liver.
GODA Nobuhito [Invited]
The 6th Conference of the Japanese Association for Hypoxia Biology
Presentation date: 2018.07
肝臓による新しい生体内糖代謝調節機構
合田 亘人
第24回肝細胞研究会
Presentation date: 2017.06
低酸素応答システムが拓く代謝性疾患の新しい病態理解
合田 亘人 [Invited]
第20回酸素ダイナミクス研究会
Presentation date: 2016.11
Metabolic diseases and HIF-1
GODA Nobuhito [Invited]
Presentation date: 2016.09
Hypoxic response and lipid metabolism
GODA Nobuhito [Invited]
International Symposium on Integration of Chemistry and Bioscience
Presentation date: 2014.01
低酸素応答システムを介した非アルコール性脂肪性肝疾患の発症制御機構
合田 亘人
第86回日本生化学会大会
Presentation date: 2013.09
低酸素応答性転写制御因子HIF-1を介した非アルコール性脂肪肝抑制機構の解明
合田 亘人
第49回日本肝臓学会
Presentation date: 2013.06
低酸素応答システムによる代謝制御
合田 亘人 [Invited]
第50回日本臨床分子医学会
Presentation date: 2013.04
HIF-1 Regulates Hepatic Lipid Metabolism in a Context-dependent Manner
GODA Nobuhito
Presentation date: 2012.12
Hypoxic responses and alcoholic fatty liver
GODA Nobuhito [Invited]
16th Congress of International Society for Biomedical Research on Alcoholism
Presentation date: 2012.09
低酸素応答による肝代謝機能制御
合田 亘人 [Invited]
第19回肝細胞研究会
Presentation date: 2012.06
HIF-1α in Myeloid Cells Promotes Adipose Tissue Remodeling Toward Insulin Resistance
Diabetes : a journal of the American Diabetes Association 10 ( 3 ) 2 - 11 2017.06
Sarcolipinヘテロ欠損マウスにおける心房機能解析
志村 大輔, 草刈 洋一郎, 笹野 哲郎, 中島 康弘, 中井 岳, 焦 其彬, 金 美花, 横田 知大, 石川 義弘, 中野 敦, 合田 亘人, 南沢 享
日本生理学雑誌 78 ( 3 ) 59 - 59 2016.05
マクロファージ特異的HIF‐1α欠損による食餌性肥満マウスの糖代謝・脂肪組織への影響
TAKIGAWA AKIKO, MAHMOOD ARSHAD, NAWAZ ALLAH, SUMI TOMONOBU, YAMAMOTO SEIJI, TSUNEYAMA KOICHI, OKABE KEISUKE, SENDA SATOKO, NAKAGAWA TAKASHI, USUI ISAO, GODA NOBUHITO, TOBE KAZUYUKI
糖尿病 58 ( Supplement 1 ) S.447 2015.04
赤池 徹, 大森 依里子, 梶村 いちげ, 宮川 幸子, 田, 合田 亘人, 南沢 享
日本小児循環器学会雑誌 30 ( Suppl. ) s332 - s332 2014.06
The manner of metabolism is different between the atrium and the ventricle
Daisukie Shimura, Qibin Jiao, Kasumi Kashikura, Keiko Endo, Tomoyoshi Soga, Nobuhito Goda, Susumu Minamisawa
FASEB JOURNAL 26 2012.04
Research paper, summary (international conference)
HIF-1 in T Cells Ameliorates Intestinal Inflammation by Controlling Regulatory T Cell Homeostasis
Masaaki Higashiyama, Ryota Hokari, Hideaki Hozumi, Chie Kurihara, Toshihide Ueda, Chikako Watanabe, Kengo Tomita, Mitsuyasu Nakamura, Shunsuke Komoto, Yoshikiyo Okada, Atsushi Kawaguchi, Shigeaki Nagao, Makoto Suematsu, Nobuhito Goda, Soichim Miura
GASTROENTEROLOGY 140 ( 5 ) S844 - S844 2011.05
Research paper, summary (international conference)
Analysis of the interaction between cells and the different types of nanosheets
Daisuke Niwa, Toshinobu Fujie, Thorsten Lang, Nobuhito Goda, Shinji Takeoka
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 239 2010.03
Research paper, summary (international conference)
pVHLは,網膜における胎児循環から成体循環への移行に必要である
栗原俊英, 栗原俊英, 久保田義顕, 小沢洋子, 小沢洋子, 田久保圭誉, 野田航介, JOHNSON Randall, 末松誠, 合田亘人, 坪田一男, 須田年生, 岡野栄之
再生医療 8 2009
HIF-1αを介した骨髄低酸素環境における造血幹細胞の静止期維持
田久保 圭誉, 平尾 敦, 合田 亘人, 新井 文用, 細川 健太郎, 吉原 宏樹, Johnson Randall, 末松 誠, 須田 年生
臨床血液 48 ( 9 ) 843 - 843 2007.09
DP-074-5 NOGマウスを用いたヒト由来がん細胞微小循環の生体内観察(第107回日本外科学会定期学術集会)
半田 寛, 末松 誠, 西銘 千代子, 山本 雄広, 合田 亘人, 島津 元秀, 北島 政樹
日本外科学会雑誌 108 ( 2 ) 474 - 474 2007.03
低酸素のバイオイメージング : Hypoxia Inducible Factor の酸素代謝における役割
塚田 孝祐, 合田 亘人, 南谷 晴之, 末松 誠
バイオイメージング 15 ( 2 ) 77 - 78 2006.10
骨髄低酸素ニッチにおけるHIF-1αを介した静止期造血幹細胞の制御機構
田久保 圭誉, 平尾 敦, 合田 亘人, 新井 文用, Randall Johnson, 末松 誠, 須田 年生
臨床血液 47 ( 9 ) 1034 - 1034 2006.09
Cross-interactions between CO and NO signaling in microvascular endothelium
M. Kajimura, M. Ishikawa, T. Adachi, K. Maruyama, N. Goda, M. Suematsu
JOURNAL OF VASCULAR RESEARCH 43 15 - 15 2006
Research paper, summary (international conference)
Increased oxygen consumption in hepatocyte-specific HIF-1-targeted mice
K. Tsukada, T. Tajima, T. Kawamura, N. Goda, R. S. Johnson, M. Suematsu
JOURNAL OF VASCULAR RESEARCH 43 45 - 45 2006
Research paper, summary (international conference)
スーパー免疫欠損NOGマウスにおけるヒト癌細胞由来腫ようマイクロ循環の生体内観察(原標題は英語)
西銘千代子, 西銘千代子, 山本雄広, 合田亘人, 中村雅登, 末水洋志, 玉置憲一, 末松誠
日本分子生物学会年会講演要旨集 28th 2005
Tリンパ球のHIF-1による急性炎症反応制御機構の解析
渡部弘志, 合田亘人, 松岡克善, RANDAIL S Johnson, 末松誠
日本分子生物学会年会講演要旨集 28th 2005
Cystathionine beta synthase as a novel gas signal transducer for CO
M Suematsu, K Hoshikawa, M Kashiba, N Goda
FASEB JOURNAL 18 ( 5 ) A1308 - A1308 2004.03
Research paper, summary (international conference)
Gas biology in organ microcirculation : How do CO and NO conduct their vasoactive receptors?
SUEMATSU Makoto, GODA Nobuhito, KAJIMURA Mayumi, KASHIBA Misato
52 36 - 36 2003.11
Hypoxia-inducible factor-1 transcription factor regulates hypoxia-induced cell cycle arrest synergically with p53 oncoprotein
N Goda, M Suematsu, RS Johnson
FASEB JOURNAL 17 ( 4 ) A18 - A18 2003.03
Research paper, summary (international conference)
Heme oxygenase-CO系による肝・門脈循環調節機構と病態 (特集 門脈圧亢進症の新展開)
末松 誠, 合田 亘人, 加柴 美里
細胞 33 ( 10 ) 388 - 371 2001.09
392 ラット精巣でのLeydig細胞によるストレス感知機構と造精機能制御
小澤 伸晃, 末松 誠, 合田 亘人, 吉村 [ヤス]典, 野澤 志朗
日本産科婦人科學會雜誌 53 ( 2 ) 355 - 355 2001.02
P-147 重金属ストレス曝露時のラット精巣における誘導型ヘムオキシゲナーゼの発現と造精機能の制御
小澤 伸晃, 末松 誠, 合田 亘人, 吉村 〓典, 野澤 志朗
日本産科婦人科學會雜誌 52 ( 2 ) "421(S - 345)" 2000.02
【胚発生と胎児発育】 フリーラジカルと胎児発育
合田 亘人, 石本 人士, 田中 守, 宮崎 豊彦, 吉村 泰典
HORMONE FRONTIER IN GYNECOLOGY 6 ( 4 ) 365 - 372 1999.12
The Heme Oxygenase-Carbon Monoxide System: A Regulator of Organ Microvascular Function
SUEMATSU Makoto, WAKABAYASHI Yoshiyuki, MAKINO Nobuya, TAKAMIYA Rina, GODA Nobuhito, ISHIMURA Yuzuru
21 ( 1 ) 19 - 25 1998.04
絨毛細胞による子宮胎盤循環の制御機構 (3月第1土曜特集 臓器微小循環--基礎から臨床へ) -- (臓器微小循環研究の進歩)
合田 亘人, 野沢 志朗
医学のあゆみ 184 ( 10 ) 801 - 804 1998.03
ヘムオキシゲナ-ゼ-CO系による臓器機能制御 (特集 多機能分子NOによる生体制御と病態)
末松 誠, 合田 亘人, 鈴木 恒陽
細胞工学 17 ( 2 ) 224 - 229 1998.02
Carbon monoxide as a regulator of microvascular function.
末松誠, 鈴木恒陽, 牧野信也, 若林良之, 柏木哲, 合田亘人, 石村巽
月刊組織培養工学 24 ( 1 ) 1998
Organic function control mechanism through carbon monoxide Immunohistologic examination of heme oxygenase distribution using monoclonal antibody. ( Ministry of Health and Welfare S ).
末松誠, 合田亘人, 若林良之, 牧野信也, 石村巽
門脈血行異常症調査研究班 平成9年度研究報告書 1998
Organic function control mechanism through carbon monoxide Intraorganic distribution of heme oxygenase. ( Ministry of Health and Welfare S ).
末松誠, 合田亘人, 若林良之, 石村巽
門脈血行異常症調査研究班 平成9年度研究報告書 1998
Carbon Monoxide-mediated Regulation of Organ Function: Characterization of Distribution of Heme Oxygenase Isoform in Liver.
末松誠, 合田亘人, 若林良之, 石村巽
特定疾患に関する分子病態研究班 平成9年度研究報告書 厚生省特定疾患調査研究班基盤研究部門 1998
Carbon monoxide modulates vesicular transport in the perfused rat liver.
T Sano, M Shiomi, Y Wakabayashi, Y Shinoda, N Goda, Y Nimura, Y Ishimaura, M Suematsu
GASTROENTEROLOGY 112 ( 4 ) A1372 - A1372 1997.04
Research paper, summary (international conference)
P-82 絨毛細胞内酸素ストレスの調節機構の解明 : ミトコンドリア呼吸鎖と一酸化窒素(NO)の相互作用
合田 亘人, 宮崎 豊彦, 名取 道也, 清河 薫, 田中 守, 吉村 泰典, 野澤 志朗
日本産科婦人科學會雜誌 49 ( 0 ) "S - 390" 1997.02
Carbon monoxide as an endogenous regulator of microvascular function.
末松誠, 若林良之, 合田亘人, 石村巽
医用電子と生体工学 35 1997
WAKABAYAHI Yoshiyuki, KASHIWAGI Satoshi, GODA Nobuhito, ISHIMURA Yuzuru, SUEMATSU Makoto
45 S95 1996.12
152 ヒト培養絨毛細胞における活性酸素生成の検討と一酸化窒素(NO)による酸素ストレスの制御機構
合田 亘人, 末松 誠, 宮崎 豊彦, 清河 薫, 若林 良之, 名取 道也, 小林 俊文, 石村 巽, 野澤 志朗
日本産科婦人科學會雜誌 48 ( 0 ) "S - 183" 1996.02
Heme oxygenase-CO pathwayによる毛細胆管収縮調節機構
篠田 雄一, 末松 誠, 若林 良之, 合田 亘人, 佐野 力, 柏木 哲, 石村 巽
日本バイオイメージング学会学術集会講演要旨集 4 97 - 98 1995.10
CARBON-MONOXIDE AS AN ENDOGENOUS MODULATOR OF CONTRACTILE PERIODICITY IN BILE CANALICULI OF RAT COUPLET HEPATOCYTES
Y SHINODA, M SUEMATSU, N GODA, Y WAKABAYASHI, Y ISHIMURA
HEPATOLOGY 22 ( 4 ) 838 - 838 1995.10
Research paper, summary (international conference)
NO and Microvascular Function-Roles in Regulation of Oxidative Stress
SUEMATSU Makoto, GODA Nobuhito, ISHIMURA Yuzuru
6 ( 2 ) 82 - 85 1995.04
CARBON-MONOXIDE - AN ENDOGENOUS MODULATOR OF HEPATIC SINUSOIDAL PERFUSION
M SUEMATSU, S KASHIWAGI, N GODA, T SANO, Y SHINODA, Y ISHIMURA
GASTROENTEROLOGY 108 ( 4 ) A1179 - A1179 1995.04
Research paper, summary (international conference)
443 新しい生体内卵胞微小循環解析法の開発 : in situ digital microfluorography によるhCG投与ラット卵胞微小循環の変化の観察
宮崎 豊彦, 合田 亘人, 山内 潤, 鄭 智誠, 清河 薫, 名取 道也, 小林 俊文, 野澤 志朗
日本産科婦人科學會雜誌 47 ( 0 ) "S - 324" 1995.02
Oxygen stress and regulation mechanism of a microcirculation function by gaseous monoxide.
末松誠, 若林良之, 篠田雄一, 合田亘人, 石村巽
治療学 29 ( 12 ) 1995
Intravital observation of platelet behavior on microvascular endothelial cells.
末松誠, 合田亘人, 石村巽
造血因子 6 ( 1 ) 1995
HYPERACUTE FAILURE OF MITOCHONDRIAL REENERGIZATION AND BILIARY TRANSPORT AFTER REPERFUSION FOLLOWING COLD ISCHEMIA IN THE RAT PERFUSED LIVER
M SUEMATSU, Y KUMAMOTO, Y SHINODA, S KASHIWAGI, N GODA, M SHIMAZU, M KITAJIMA, Y ISHIMURA
HEPATOLOGY 20 ( 4 ) A176 - A176 1994.10
Research paper, summary (international conference)
NATORI Michiya, TANAKA Mamoru, ISHIMOTO Hitoshi, GOHDA Nobuhito, KIYOKAWA Kaoru, YAMAUCHI Jun, MIYAZAKI Toyohiko, KOBAYASHI Toshifumi, NOZAWA Shiro, TAKAGI Tsukasa
46 ( 7 ) 562 - 566 1994
TANAKA Mamoru, NATORI Michiya, ISHIMOTO Hitoshi, GOHDA Nobuhito, KIYOKAWA Kaoru, YAMAUCHI Jyun, MIYAZAKI Toyohiko, KOBAYASHI Toshifumi, NOZAWA Shiro
46 ( 11 ) 1229 - 1233 1994
Science and Engineering Laboratory 1B V
School of Creative Science and Engineering
2024 fall semester
Science and Engineering Laboratory 1A IV
School of Creative Science and Engineering
2024 spring semester
Science and Engineering Laboratory 1B V
School of Advanced Science and Engineering
2024 fall semester
Science and Engineering Laboratory 1A IV
School of Advanced Science and Engineering
2024 spring semester
Life Science and Medical Bio-science Laboratory II [S Grade]
School of Advanced Science and Engineering
2024 spring semester
Life Science and Medical Bio-science Laboratory II
School of Advanced Science and Engineering
2024 spring semester
Introduction to Clinical Medicine [S Grade]
School of Advanced Science and Engineering
2024 fall semester
Life Science and Medical Bio-science Seminar II [S Grade]
School of Advanced Science and Engineering
2024 fall semester
Life Science and Medical Bio-science Seminar II
School of Advanced Science and Engineering
2024 fall semester
Life Science and Medical Bio-science Seminar I [S Grade]
School of Advanced Science and Engineering
2024 spring semester
Anatomy and Histology:Laboratory [S Grade]
School of Advanced Science and Engineering
2024 fall semester
Life Science and Medical Bio-science Seminar I
School of Advanced Science and Engineering
2024 spring semester
Life Science and Medical Bio-science Laboratory V
School of Advanced Science and Engineering
2024 fall semester
Life Science and Medical Bio-science Laboratory IV
School of Advanced Science and Engineering
2024 spring semester
Master's Thesis (Department of Life Science and Medical Bioscience)
Graduate School of Advanced Science and Engineering
2024 full year
Master's Thesis (Department of Life Science and Medical Bioscience)
Graduate School of Advanced Science and Engineering
2024 full year
Research on Molecular Medicine and Biochemistry
Graduate School of Advanced Science and Engineering
2024 full year
Seminar on Molecular Medicine and Biochemistry D
Graduate School of Advanced Science and Engineering
2024 fall semester
Seminar on Molecular Medicine and Biochemistry C
Graduate School of Advanced Science and Engineering
2024 spring semester
Research on Molecular Medicine and Biochemistry
Graduate School of Advanced Science and Engineering
2024 full year
Seminar on Molecular Medicine and Biochemistry D
Graduate School of Advanced Science and Engineering
2024 fall semester
Seminar on Molecular Medicine and Biochemistry C
Graduate School of Advanced Science and Engineering
2024 spring semester
Graduate School of Advanced Science and Engineering
2024 spring semester
Practical Training for Career Building
Graduate School of Advanced Science and Engineering
2024 full year
Research on Molecular Medicine and Biochemistry
Graduate School of Advanced Science and Engineering
2024 full year
Science and Engineering Laboratory 1B V
School of Fundamental Science and Engineering
2024 fall semester
Science and Engineering Laboratory 1A IV
School of Fundamental Science and Engineering
2024 spring semester
Faculty of Science and Engineering Graduate School of Advanced Science and Engineering
Affiliated organization Global Education Center
Waseda Research Institute for Science and Engineering Concurrent Researcher
2022 藤枝 咲帆
2020 林 絵莉子, 鈴木 達也
2019 大串 悠斗, 田中 大志
新規ヘパトカインのニューレグリン1による糖代謝制御機構の解明
2016 合田 亘人, 新井 理智, 有村 祐次郎, 大野 友美絵
ニューレグリン1を介した肝臓-膵臓の臓器連関による糖代謝制御機構の解明
2015 新井 理智, 鈴木 智大, 佐山 慧門, 有村 祐次郎, 大野 友美絵
2015 横野 航太, 山田 祥子, 横関 京介, 田中 裕子, 橋本 昂士郎
死細胞から放出されるシグナル分子の同定とその病態生理学的役割の解明
2011 松田 七美
Click to view the Google Scholar page.