Updated on 2023/06/05

写真a

 
WATANABE, Hironori
 
Affiliation
Research Council (Research Organization), Sustainable Energy & Environmental Society Open Innovation Research Organization
Job title
Junior Researcher(Assistant Professor)

Research Experience

  • 2022.10
    -
    Now

    Waseda University

  • 2022.04
    -
    Now

    Waseda University   Advanced Research Center for Human Sciences

  • 2020.04
    -
    2022.03

    Toyo University

  • 2019.04
    -
    2020.03

    Toyo University

  • 2011.04
    -
    2015.03

    アルケア株式会社

Education Background

  • 2015.04
    -
    2019.03

    National Institute of Fitness and Sports in Kanoya  

  • 2009.04
    -
    2011.03

    National Institute of Fitness and Sports in Kanoya  

  • 2005.04
    -
    2009.03

    National Institute of Fitness and Sports in Kanoya  

Professional Memberships

  • 2023
    -
    Now

    日本生理学会

  • 2022
    -
    Now

    日本生気象学会

  • 2015
    -
    Now

    日本体力医学会

Research Areas

  • Sports sciences / Neurosurgery

Research Interests

  • 体温調節

  • 課題難度

  • 呼吸調節

  • 脳循環

  • 経頭蓋超音波ドップラー法

  • 脳波

  • 経頭蓋磁気刺激法

  • 筋電図

▼display all

Awards

  • 優秀講演賞

    2018.12   計測自動制御学会システムインテグレーション部門講演会  

 

Papers

  • Greater task difficulty during unilateral motor tasks changes intracortical inhibition and facilitation in the ipsilateral primary motor cortex in young men

    Hironori Watanabe, Shigehiko Ogoh, Naokazu Miyamoto, Hiroaki Kanehisa, Yasuhide Yoshitake

    Neuroscience Letters     137293 - 137293  2023.05  [Refereed]

    Authorship:Lead author

    DOI

  • Can Alterations in Cerebrovascular CO2 Reactivity Be Identified Using Transfer Function Analysis without the Requirement for Carbon Dioxide Inhalation?

    Shigehiko Ogoh, Hironori Watanabe, Shotaro Saito, James P. Fisher, Erika Iwamoto

    Journal of Clinical Medicine   12 ( 6 ) 2441  2023.03  [Refereed]

     View Summary

    The present study aimed to examine the validity of a novel method to assess cerebrovascular carbon dioxide (CO2) reactivity (CVR) that does not require a CO2 inhalation challenge, e.g., for use in patients with respiratory disease or the elderly, etc. In twenty-one healthy participants, CVR responses to orthostatic stress (50° head-up tilt, HUT) were assessed using two methods: (1) the traditional CO2 inhalation method, and (2) transfer function analysis (TFA) between middle cerebral artery blood velocity (MCA V) and predicted arterial partial pressure of CO2 (PaCO2) during spontaneous respiration. During HUT, MCA V steady-state (i.e., magnitude) and MCA V onset (i.e., time constant) responses to CO2 inhalation were decreased (p < 0.001) and increased (p = 0.001), respectively, indicative of attenuated CVR. In contrast, TFA gain in the very low-frequency range (VLF, 0.005–0.024 Hz) was unchanged, while the TFA phase in the VLF approached zero during HUT (−0.38 ± 0.59 vs. 0.31 ± 0.78 radians, supine vs. HUT; p = 0.003), indicative of a shorter time (i.e., improved) response of CVR. These findings indicate that CVR metrics determined by TFA without a CO2 inhalation do not track HUT-evoked reductions in CVR identified using CO2 inhalation, suggesting that enhanced cerebral blood flow response to a change in CO2 using CO2 inhalation is necessary to assess CVR adequately.

    DOI

  • An Evaluation of Change in the Physical Output in Female Youth Football Players During a Game

    Shigehiko Ogoh, Anna Oue, Hironori Watanabe, Shotaro Saito, Kento Dora, Nana Ogoh, Maki Osuga, Tetsuya Hasegawa, Keisho Katayama

    European Journal of Sport Sciences   2 ( 2 ) 1 - 7  2023.03  [Refereed]

     View Summary

    <jats:p>This study evaluated the time-to-time aerobic and anaerobic exercise intensities, calculated using the Global Positioning System (GPS), using laboratory measurements of individual physical fitness throughout the game in each female youth football player. In addition, we examine if the anaerobic exercise index calculated by only GPS data presents this evaluation to examine its validity. In the laboratory, the oxygen uptake (V̇O2) matched with moving speed was identified during an incremental exercise test on the treadmill, and the ventilatory (anaerobic) threshold was also analysed to identify individual aerobic and anaerobic exercise intensities. Using these laboratory data, time-to-time changes in individual relative running intensity (aerobic and anaerobic) were visualised from individual GPS data during a football game, and an individual’s sprint output (ability) during the game was evaluated. An index of running intensity and the percentage of anaerobic exercise over the game provided by the GPS software (equivalent distance index [%EDI] and anaerobic index [AI]) did not present the actual individual exercise intensity (ICC(2,1), absolute agreement=−0.031; P=0.596) and percentage of anaerobic exercise (ICC(2,1), absolute agreement=−0.003; P=0.698) values during the game, respectively. These findings suggest that only GPS measurement cannot present the individual actual exercise intensity during a football game because of different individual fitness levels to the same running speed.</jats:p>

    DOI

  • Influence of cardiac output response to the onset of exercise on cerebral blood flow

    Shotaro Saito, Takuro Washio, Hironori Watanabe, Keisho Katayama, Shigehiko Ogoh

    European Journal of Applied Physiology   122 ( 8 ) 1939 - 1948  2022.08  [Refereed]

    DOI

  • Cerebral blood velocity and arterial pressure at the onset of exercise: potential influence of the cardiopulmonary baroreflex

    Shigehiko Ogoh, Shotaro Saito, Hironori Watanabe, Keisho Katayama

    Clinical Autonomic Research   32 ( 2 ) 143 - 146  2022.04  [Refereed]

    DOI

  • Site-specific different dynamic cerebral autoregulation and cerebrovascular response to carbon dioxide in posterior cerebral circulation during isometric exercise in healthy young men

    Takuro Washio, Hironori Watanabe, Kazuya Suzuki, Shotaro Saito, Shigehiko Ogoh

    Autonomic Neuroscience   238   102943 - 102943  2022.03  [Refereed]

    DOI

  • Validity of transcranial Doppler ultrasonography-determined dynamic cerebral autoregulation estimated using transfer function analysis

    Hironori Watanabe, Takuro Washio, Shotaro Saito, Ai Hirasawa, Rina Suzuki, Shigeki Shibata, R. Matthew Brothers, Shigehiko Ogoh

    Journal of Clinical Monitoring and Computing   36 ( 6 ) 1711 - 1721  2022.01  [Refereed]

    Authorship:Lead author

    DOI

  • Acute Gravitational Stress Selectively Impairs Dynamic Cerebrovascular Reactivity in the Anterior Circulation Independent of Changes to the Central Respiratory Chemoreflex

    Hironori Watanabe, Shotaro Saito, Takuro Washio, Damian Miles Bailey, Shigehiko Ogoh

    Frontiers in Physiology   12  2022.01  [Refereed]

    Authorship:Lead author

     View Summary

    Cerebrovascular reactivity (CVR) to changes in the partial pressure of arterial carbon dioxide (PaCO2) is an important mechanism that maintains CO2 or pH homeostasis in the brain. To what extent this is influenced by gravitational stress and corresponding implications for the regulation of cerebral blood flow (CBF) remain unclear. The present study examined the onset responses of pulmonary ventilation (V̇E) and anterior middle (MCA) and posterior (PCA) cerebral artery mean blood velocity (Vmean) responses to acute hypercapnia (5% CO2) to infer dynamic changes in the central respiratory chemoreflex and cerebrovascular reactivity (CVR), in supine and 50° head-up tilt (HUT) positions. Each onset response was evaluated using a single-exponential regression model consisting of the response time latency [CO2-response delay (t0)] and time constant (τ). Onset response of V̇E and PCA Vmean to changes in CO2 was unchanged during 50° HUT compared with supine (τ: V̇E, p = 0.707; PCA Vmean, p = 0.071 vs. supine) but the MCA Vmean onset response was faster during supine than during 50° HUT (τ: p = 0.003 vs. supine). These data indicate that gravitational stress selectively impaired dynamic CVR in the anterior cerebral circulation, whereas the posterior circulation was preserved, independent of any changes to the central respiratory chemoreflex. Collectively, our findings highlight the regional heterogeneity underlying CBF regulation that may have translational implications for the microgravity (and hypercapnia) associated with deep-space flight notwithstanding terrestrial orthostatic diseases that have been linked to accelerated cognitive decline and neurodegeneration.

    DOI

  • Effect of breath-hold on the responses of arterial blood pressure and cerebral blood velocity to isometric exercise

    Hironori Watanabe, Takuro Washio, Shotaro Saito, Shigehiko Ogoh

    European Journal of Applied Physiology   122 ( 1 ) 157 - 168  2022.01  [Refereed]

    Authorship:Lead author

    DOI

  • Integrated respiratory chemoreflex-mediated regulation of cerebral blood flow in hypoxia: Implications for oxygen delivery and acute mountain sickness.

    Shigehiko Ogoh, Takuro Washio, Benjamin S. Stacey, Hayato Tsukamoto, Angelo Iannetelli, Thomas S. Owens, Thomas A. Calverley, Lewis Fall, Christopher J. Marley, Shotaro Saito, Hironori Watanabe, Takeshi Hashimoto, Soichi Ando, Tadayoshi Miyamoto, Damian M. Bailey

    Experimental physiology   106 ( 9 ) 1922 - 1938  2021.08  [Refereed]

     View Summary

    <h4>New findings</h4>What is the central question of this study? To what extent do hypoxia-induced changes in the peripheral and central respiratory chemoreflex modulate anterior and posterior cerebral oxygen delivery, with corresponding implications for susceptibility to acute mountain sickness? What is the main finding and its importance? We provide evidence for site-specific regulation of cerebral blood flow in hypoxia that preserves oxygen delivery in the posterior but not the anterior cerebral circulation, with minimal contribution from the central respiratory chemoreflex. External carotid artery vasodilatation might prove to be an alternative haemodynamic risk factor that predisposes to acute mountain sickness.<h4>Abstract</h4>The aim of the present study was to determine the extent to which hypoxia-induced changes in the peripheral and central respiratory chemoreflex modulate anterior and posterior cerebral blood flow (CBF) and oxygen delivery (CDO2 ), with corresponding implications for the pathophysiology of the neurological syndrome, acute mountain sickness (AMS). Eight healthy men were randomly assigned single blind to 7 h of passive exposure to both normoxia (21% O2 ) and hypoxia (12% O2 ). The peripheral and central respiratory chemoreflex, internal carotid artery, external carotid artery (ECA) and vertebral artery blood flow (duplex ultrasound) and AMS scores (questionnaires) were measured throughout. A reduction in internal carotid artery CDO2 was observed during hypoxia despite a compensatory elevation in perfusion. In contrast, vertebral artery and ECA CDO2 were preserved, and the former was attributable to a more marked increase in perfusion. Hypoxia was associated with progressive activation of the peripheral respiratory chemoreflex (P < 0.001), whereas the central respiratory chemoreflex remained unchanged (P > 0.05). Symptom severity in participants who developed clinical AMS was positively related to ECA blood flow (Lake Louise score, r = 0.546-0.709, P = 0.004-0.043; Environmental Symptoms Questionnaires-Cerebral symptoms score, r = 0.587-0.771, P = 0.001-0.027, n = 4). Collectively, these findings highlight the site-specific regulation of CBF in hypoxia that maintains CDO2 selectively in the posterior but not the anterior cerebral circulation, with minimal contribution from the central respiratory chemoreflex. Furthermore, ECA vasodilatation might represent a hitherto unexplored haemodynamic risk factor implicated in the pathophysiology of AMS.

    DOI PubMed

  • Effect of intermittent isometric handgrip exercise protocol with short exercise duration on cognitive performance

    Shotaro Saito, Takuro Washio, Hironori Watanabe, Soichi Ando, Shigehiko Ogoh

    The Journal of Physiological Sciences   71 ( 1 )  2021.04  [Refereed]

     View Summary

    Abstract

    The handgrip exercise, a small muscle exercise, is useful for exercise therapy, particularly in the elderly and bedridden patients. The isometric handgrip (IHG) exercise has been utilized in training programs to reduce resting blood pressure; however, the acute effects of the IHG exercise on cognitive performance are not fully understood. The present study aimed to investigate the effect of an intermittent IHG exercise protocol with short exercise duration, which minimizes the arterial blood pressure response to exercise, on cognitive performance. Twenty-two young healthy subjects performed the intermittent IHG exercise protocol, which consisted of 30-s IHG and 45-s recovery × 16 trials; the exercise intensity of the IHG exercise was 30% of the maximal voluntary contraction. Cognitive performance was evaluated before and after the exercise with the Go/No-Go and memory recognition tasks. Specifically, the reaction time (RT) and performance accuracy were measured. The intermittent IHG exercise protocol did not change the RT or performance accuracy of either the Go/No-Go task (P = 0.222 and P = 0.260, respectively) or the memory recognition task (P = 0.427 and P = 0.245, respectively). These findings suggest that the intermittent IHG exercise protocol with short exercise duration may not provide enough stimulation to improve cognitive performance despite being useful as a safe exercise therapy in the elderly and in patients with cardiovascular disease.

    DOI PubMed

  • Effects of acute interval handgrip exercise on cognitive performance

    Takuro Washio, Kazuya Suzuki, Shotaro Saito, Hironori Watanabe, Soichi Ando, R. Matthew Brothers, Shigehiko Ogoh

    Physiology &amp; Behavior   232   113327 - 113327  2021.04  [Refereed]

    DOI PubMed

  • Reconstruction of net force fluctuations from surface EMGs of multiple muscles in steady isometric plantarflexion

    Ryosei Suzuki, Hiroaki Kanehisa, Sohei Washino, Hironori Watanabe, Minoru Shinohara, Yasuhide Yoshitake

    Experimental Brain Research   239 ( 2 ) 601 - 612  2021.01  [Refereed]

    DOI PubMed

  • Dynamic cerebral autoregulation in anterior and posterior cerebral circulation during cold pressor test

    Takuro Washio, Hironori Watanabe, Shigehiko Ogoh

    The Journal of Physiological Sciences   70 ( 1 )  2020.01  [Refereed]

     View Summary

    Abstract

    We hypothesized that cerebral blood flow (CBF) regulation in the posterior circulation differs from that of the anterior circulation during a cold pressor test (CPT) and is accompanied by elevations in arterial blood pressure (ABP) and sympathetic nervous activity (SNA). To test this, dynamic cerebral autoregulation (dCA) in the middle and posterior cerebral arteries (MCA and PCA) were measured at three different conditions: control, early phase of the CPT, and the late phase of the CPT. The dCA was examined using a thigh cuff occlusion and release technique. The MCA and PCA blood velocities were unchanged at CPT compared with the control conditions despite an elevation in the ABP. The dCA in both the MCA and PCA remained unaltered at CPT. These findings suggest that CPT-induced elevations in the ABP and SNA did not cause changes in the CBF regulation in the posterior circulation compared with the anterior circulation.

    DOI PubMed

  • Corticospinal Excitability During Actual and Imaginary Motor Tasks of Varied Difficulty

    Hironori Watanabe, Nobuaki Mizuguchi, Dean Leonard Mayfield, Yasuhide Yoshitake

    Neuroscience   391   81 - 90  2018.11  [Refereed]

    Authorship:Lead author

    DOI PubMed

  • Can Face Swapping Technology Facilitate Mental Imagery Training ?

    Haruka Matsumura, Hironori Watanabe, ChenTai Chih, Takafumi Taketomi, Yasuhide Yoshitake, Alexandor Plopski, Christian Sandor, Hirokazu Kato

    International Conference on Artificial Reality and Telexistence Eurographics Symposium on Virtual Environments     1 - 2  2017.12  [Refereed]

  • Unintended activity in homologous muscle during intended unilateral contractions increases with greater task difficulty

    Hironori Watanabe, Hiroaki Kanehisa, Yasuhide Yoshitake

    European Journal of Applied Physiology   117 ( 10 ) 2009 - 2019  2017.08  [Refereed]

    Authorship:Lead author

    DOI PubMed

  • Relationships of ultrasound measures of intrinsic foot muscle cross-sectional area and muscle volume with maximum toe flexor muscle strength and physical performance in young adults

    Takashi Abe, Kota Tayashiki, Miyuki Nakatani, Hironori Watanabe

    Journal of Physical Therapy Science   28 ( 1 ) 14 - 19  2016  [Refereed]

    DOI PubMed

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Presentations

  • 常に快適な室内環境の創出を目指して

    渡邊裕宣  [Invited]

    次世代ヒートポンプ技術戦略研究コンソーシアム講演会 

    Presentation date: 2023.05

  • Brain regions related with thermal sensation

    Hironori Watanabe, Satoshi Shibuya, Taisuke Sugi, Issei Kato, Yufuko Kataoka, Kiyoshi Saito, Kei Nagashima

    第100回日本生理学会大会 

    Presentation date: 2023.03

  • ヒトの温冷感の形成に関連する脳領域の解明

    渡邊 裕宣,渋谷 賢,杉 泰佑,加藤 一聖,片岡 由布子,永島 計

    第61回日本生気象学会大会 

    Presentation date: 2022.11

  • Validity of transcranial Doppler ultrasonography-determined dynamic cerebral autoregulation estimated using transfer function analysis

    Hironori Watanabe, Takuro Washio, Shotaro Saito, Ai Hirasawa, Rina Suzuki, Shigeki Shibata, R Matthew Brothers, Shigehiko Ogoh

    Annual Meeting of American College of Sports Medicine 

    Presentation date: 2022.06

  • 精神的疲労と脳血流

    渡邊裕宣  [Invited]

    第36回計測自動制御学会ライフエンジニアリング部門 

    Presentation date: 2021.10

  • 精神的疲労は前頭前野–運動野の機能的結合性を低下させる?

    渡邊裕宣, 鷲尾拓郎, 齋藤祥太郎, 小河繁彦

    第76回日本体力医学会大会 

    Presentation date: 2021.09

  • 脳自己調節機能同定のための基礎研究

    渡邊裕宣, 鷲尾拓郎, 平澤愛, 柴田茂貴, 小河繁彦

    第74回日本体力医学会大会 

    Presentation date: 2019.09

  • Skin acts as a medium of intermuscular force transmission inhuman

    Hironori Watanabe, Sohei Washino, Keigo Taniguchi, Masaki Katayose, Hiroaki Kanehisa, Yasuhide Yoshitake

    International Society of Biomechanics 

    Presentation date: 2019.08

  • 動作観察による運動学習を促進させる顔変換システムの有用性の検証

    渡邊裕宣, 松村遥, 武富貴史, 権田智也, Alexander Plopski, 加藤博一, 吉武康栄

    第19回計測自動制御学会システムインテグレーション部門講演会 

    Presentation date: 2018.12

  • Can face swapping technology facilitate mental imagery training ?

    Haruka Matsumura, Hironori Watanabe, Chen Tai Chen, Takafumi Taketomi, Yasuhide Yoshitake Alexander Plopski, Christian Sando, Hirokazu Kato

    International Society of Biomechanics 

    Presentation date: 2017.12

  • 運動学習のための顔交換技術の初期検討

    松村遥, 渡邊裕宣, 陳泰之, 武富貴史, 吉武康栄, Alexander Plopski, Christian Sando, 加藤博一

    ディアエクスペリエンス・バーチャル環境基礎研究会 

    Presentation date: 2017.10

  • ヒトにおける筋間張力伝達の有無と伝達媒体

    吉武康栄, 谷口圭吾, 渡邊裕宣, 鷲野壮平, 内田大樹, 片寄正樹

    第72回日本体力医学会大会 

    Presentation date: 2017.09

  • 片側性力調節課題時の難易度と同側一次運動野の皮質内抑制・促通機構の解明

    渡邊裕宣, 陳泰之, 吉武康栄

    第72回日本体力医学会大会 

    Presentation date: 2017.09

  • Relation between inspiratory muscle strength and recruitment onset of neck inspiratory muscles

    Sohei Washino, Hironori Watanabe, Hiroaki Kanehisa, Yasuhide Yoshitake

    Presentation date: 2017.06

  • Motor execution and imagery with greater task difficulty increases corticospinal excitability

    Presentation date: 2017.06

  • 片側性随意的筋活動時に反対側同名筋に発生する不随意的筋活動の特性解明

    渡邊裕宣, 吉武康栄

    第67回日本体育学会大会 

    Presentation date: 2016.09

  • 大腿直筋は股関節屈曲筋力発揮時に筋内 common drive が小さい

    吉武康栄, 渡邊裕宣, 宮本直和

    第71回日本体力医学会大会 

    Presentation date: 2016.09

  • 片側性力調節課題時の難易度と両側一次運動野の興奮性の相違

    渡邊裕宣, 吉武康栄

    第71回日本体力医学会大会 

    Presentation date: 2016.09

  • 異なる Flow rate および吸気量位時の 吸気補助筋活動の振る舞い

    鷲野壮平, 黒原尚武, 渡邊裕宣, 吉武康栄

    第70回日本体力医学会大会 

    Presentation date: 2015.09

  • 片側性筋収縮時の反対側の不随意的筋活動は課題難易度に依存するか

    渡邊裕宣, 黒原尚武, 吉武康栄

    第70回日本体力医学会大会 

    Presentation date: 2015.09

  • Unintended contralateral activity increased during ipsilateral intended contraction with greater task difficulty

    Hironori Watanabe, Shobu Kurohara, Yasuhide Yoshitake

    The 10th Progress in motor control 

    Presentation date: 2015.07

  • 市販のマスク着用が有酸素性運動時の生理応答に及ぼす影響

    渡邊裕宣, 山本正嘉

    第22回日本トレーニング科学会大会 

    Presentation date: 2009.12

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Syllabus

Teaching Experience

  • 生体環境の生理学

    早稲田大学  

    2022.04
    -
    Now
     

  • 生涯スポーツ演習

    電気通信大学  

    2020.04
    -
    Now
     

  • 健康・スポーツ科学論

    明星大学  

    2020.04
    -
    2022.03
     

  • 硬式テニス

    明星大学  

    2019.04
    -
    2020.03
     

 

Sub-affiliation

  • Faculty of Human Sciences   School of Human Sciences (Online Degree Program)