Updated on 2025/05/12

写真a

 
NAKANISHI, Takuya
 
Affiliation
Research Council (Research Organization), Comprehensive Research Organization
Job title
Senior Researcher(Professor)
Degree
Doctor of Science ( Hokkaido University )

Research Experience

  • 2022.07
    -
    Now

    Waseda University   Comprehensive Research Organization   Senior Researcher (Professor)

  • 2021.12
    -
    2022.06

    National Institute for Materials Science (NIMS)   Center for Green Research on Energy and Environmental Materials   NIMS Special Researcher

  • 2021.04
    -
    2021.11

    Waseda University   Comprehensive Research Organization   Senior Researcher (Professor)

  • 2019.04
    -
    2021.03

    Waseda University   Research Organization for Nano & Life Innovation   Guest Senior Researcher (Guest Professor)

  • 2017.11
    -
    2021.03

    Waseda University Academic Solutions Corporation   Project Planning and Development Dept.   Supervisory Researcher/Consultant

  • 2016.10
    -
    2017.10

    National Institute of Advanced Industrial Science and Technology (AIST)   Computational Bio Big-Data Open Innovation Laboratory   Invited Researcher

  • 2014.04
    -
    2016.09

    Waseda University   Institute for Nanoscience & Nanotechnology [reorganized as Research Organization for Nano & Life Innovation in 2015]   Senior Researcher (Professor)

  • 2013.04
    -
    2014.03

    Waseda University   Institute for Nanoscience & Nanotechnology   Researcher (Associate Professor)

  • 2009.04
    -
    2013.03

    Waseda University   Faculty of Science and Engineering   Researcher (Associate Professor)

  • 2005.04
    -
    2009.03

    Waseda University   Consolidated Research Institute for Advanced Science and Medical Care   Visiting Associate Professor (full-time)

  • 2004.09
    -
    2005.03

    Waseda University   Consolidated Research Institute for Advanced Science and Medical Care   Visiting Lecturer (full-time)

  • 2002.04
    -
    2004.08

    JSPS Research Fellow (PD)

  • 1998.09
    -
    2002.03

    Waseda University   Kagami Memorial Laboratory for Materials Science and Technology   Visiting Research Associate

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Education Background

  • 　
    -
    1998

    Hokkaido University   Graduate School of Science   Division of Chemistry (Doctoral Course)  

  • 　
    -
    1995

    Hokkaido University   Graduate School of Science   Division of Chemistry (Master's Course)  

  • 　
    -
    1993

    Hokkaido University   Faculty of Science   Department of Chemistry  

Committee Memberships

  • 2016.07
    -
    2021.02

    The Electrochemical Society of Japan  Member of Public Relations Committee

  • 2017.01
    -
    2017.05

    2017 International Workshop on Electrified Interfaces for Energy Conversions (EIC2017), Organizing Committee Member

  • 2014.12
    -
    2015.06

    Symposium on Molecular Chirality 2015 (MC2015), Local Committee Member in Executive Committee

  • 2013.03
    -
    2015.02

    The Electrochemical Society of Japan  Member of Convention Planning Committee

  • 2013.10
    -
    2014.11

    10th International Symposium on Electrochemical Micro & Nanosystem Technologies (EMNT2014), Secretary General

  • 2012.10
    -
    2013.07

    12th Conference for BioSignal and Medicine (CBSM2013), Executive Committee Member

  • 2011.03
    -
    2013.02

    The Electrochemical Society of Japan  Member of Editorial Committee

  • 2010.03
    -
    2013.02

    The Electrochemical Society of Japan  Member of International Exchange Committee

  • 2010.08
    -
    2011.09

    The 62nd Annual Meeting of the International Society of Electrochemistry (62nd Annual ISE Meeting), Local Organizing Committee Member

  • 2009.03
    -
    2011.02

    The Electrochemical Society of Japan  Secretary of Kanto Branch

  • 2009.01
    -
    2009.05

    12th Annual Meeting of Japanese Society for Marine Biotechnology, Executive Committee Member

  • 2007.03
    -
    2009.02

    The Electrochemical Society of Japan  Member of Convention Planning Committee

  • 2005.03
    -
    2007.02

    The Electrochemical Society of Japan  Councilor

  • 2004.03
    -
    2006.02

    The Electrochemical Society of Japan  Secretary of Kanto Branch

  • 2004.01
    -
    2004.10

    5th International Symposium on Electrochemical Micro & Nanosystem Technologies (EMT2004), Organizing Committee Member

  • 1999.12
    -
    2000.11

    The 5th Perpendicular Magnetic Recording Conference (PMRC2000), Member of Publication Division in Executive Committee

  • 2000.04
    -
    2000.09

    The 24th Annual Conference on Magnetics in Japan, Member of Local Secretariat in Executive Committee,

  • 1999.01
    -
    1999.05

    ’99 Asian Conference on Electrochemistry ('99 ACEC), Organizing Committee Member

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Professional Memberships

  • 　
    　
    　

    The Japan Society of Vacuum and Surface Science

  • 　
    　
    　

    The Japan Society of Applied Physics

  • 　
    　
    　

    The Chemical Society of Japan

  • 　
    　
    　

    The Electrochemical Society of Japan

Research Areas

  • Functional solid state chemistry / Fundamental physical chemistry / Nanomaterials / Nanometer-scale chemistry

Research Interests

  • Characterization of Nanomaterials

  • Synthesis of Nanomaterials

  • Molecular Recognition

  • Films and Assemblies

  • Electrochemistry

  • Surfaces and Interfaces

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Awards

  • Poster Award, Chirality 2006 - 18th International Symposium on Chirality (ISCD-18)

    2006.06  

  • Best Poster Presentation Award, The 56th Annual Meeting of the International Society of Electrochemistry

    2005.09  

  • Poster Award, Chirality 2003 - 15th International Symposium on Chirality (ISCD-15)

    2003.10  

 

Papers

  • How Temperature Change Affects the Lattice Parameters, Molecular Conformation, and Reaction Cavity in Enantiomeric and Racemic Crystals of Thalidomide

    Ayaka Matsumoto, Kenta Nakagawa, Takuya Nakanishi, Akiko Sekine, Sosuke Kojo, Mizuki Kira, Sota Sato, Norio Shibata, Toru Asahi

    Journal of the American Chemical Society   147 ( 14 ) 11988 - 11997  2025.04  [Refereed]  [International journal]

    DOI

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  • Electrochemical Oxidative Desorption of Adsorbed Sulfur Species on (111) Surfaces of Single Crystals of Pure Pt and Pt-Based Bimetallic Alloys

    Makoto Aoki, Tamao Shishido, Tetsuro Morooka, Takuya Nakanishi, Takuya Masuda

    The Journal of Physical Chemistry C   129 ( 4 ) 2122 - 2131  2025.01  [Refereed]  [International journal]

    DOI

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  • Wavelength dependence of linear birefringence and linear dichroism of Bi2−xPbxSr2CaCu2O8+δ single crystals

    Keigo Tokita, Kenta Nakagawa, Kun Zhang, Komei Okano, Masataka Matsumoto, Takuya Nakanishi, Masaki Fujita, Toru Asahi

    Scientific Reports   14   27102  2024.11  [Refereed]  [International journal]

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  • Interaction between intrinsically disordered proteins Praja1 and α-synuclein on gold electrodes

    Wataru Mori, Wataru Onodera, Terutoshi Kojima, Toru Asahi, Takuya Nakanishi

    Chemistry Letters   53 ( 11 ) upae205  2024.11  [Refereed]  [International journal]

    Authorship：Last author, Corresponding author

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  • Potential-Dependent and Face Orientation-Dependent Electrochemical Oxidative Desorption Behavior of Sulfur Species Adsorbed on Platinum Single-Crystal Surfaces

    Tetsuro Morooka, Tamao Shishido, Ruttala Devivaraprasad, Ganesan Elumalai, Makoto Aoki, Tetsuroh Shirasawa, Takuya Nakanishi, Atsushi Ishikawa, Toshihiro Kondo, Takuya Masuda

    The Journal of Physical Chemistry C   128 ( 39 ) 16426 - 16436  2024.10  [Refereed]  [International journal]

    DOI

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    1
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  • Chiral Inversion of Thalidomide During Crystal Growth by Sublimation

    Mizuki Kira, Yuta Shiga, Kenta Nakagawa, Ayaka Matsumoto, Keigo Tokita, Yukana Terasawa, Kun Zhang, Koichi Tsutao, Takuya Nakanishi, Satoshi Yoshida, Sota Sato, Norio Shibata, Toru Asahi

    Crystal Growth & Design   24 ( 8 ) 3133 - 3139  2024.04  [Refereed]  [International journal]

    　View Summary

    3′-(N-Phthalimido)glutarimide, commonly known as thalidomide (TD), is one of the most famous chiral drugs, because of its tragic history. Although the R-enantiomers of TD have positive medical effects, the S-enantiomers have dangerous side effects, and consequently, the enantiomeric purity of TD in a solid state and the chiral inversion of TD in physiological conditions have attracted considerable attention and prompted discussion on the “TD paradox”. Subsequently, the physicochemical properties of TD in the solid state have been indicated to be as essential as those in the solution state for understanding the pharmacodynamics and pharmacokinetics of TD. Herein, we demonstrate that the sublimation method is beneficial in the crystal growth of TD compared with solvent-evaporation methods. Structural and optical analyses demonstrated that sublimination produced very thin, transparent, and defect-free single crystals with high crystal-surface parallelism; chromatographic analysis suggested that a chiral inversion of TD molecules occurs during the sublimation even beneath the melting point under ambient humidity. The potential occurrence of chiral inversion of TD in the gas phase with atmospheric water vapor is a crucial finding in the use of sublimation in purifying chiral drugs to avoid adverse drug-induced outcomes. The crystal growth and potential chiral inversion of TD by sublimation should contribute to providing important information for pharmaceutical sciences and industry.

    DOI

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    1
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  • Debonding-on-demand adhesives based on photo-reversible cycloaddition reactions

    Moeka Inada, Tatsuhiro Horii, Toshinori Fujie, Takuya Nakanishi, Toru Asahi, Kei Saito

    Materials Advances   4 ( 5 ) 1289 - 1296  2023.01  [Refereed]  [International journal]

    　View Summary

    Debonding-on-demand (DoD) adhesives, which have the ability to repeatedly adhere and release in response to external stimuli, are attracting attention as sustainable functional materials. DoD adhesives can be designed by fabricating dynamic covalent bonds and using polymer cleavage and flow generation by dynamic mechanisms that respond autonomously to external stimuli, such as heat and light. However, the typical DoD adhesives using dynamic covalent bonds mainly utilize heat-induced systems, and the practical application of these adhesives at room temperature and ambient pressure is challenging. In this study, we report a DoD adhesive system based on a polymer that is fabricated by the reversible cycloaddition reaction of coumarin-terminated four-arm siloxane monomers. Thermophysical property analysis of the obtained polymers confirmed that photoinduced fluidization was based on the reversible crosslinking and decrosslinking reactions of the monomers. These thermophysical properties can directly control the stiffness of the polymers, providing mechanistic evidence of DoD adhesion. This simple siloxane-based reversible cycloaddition system exhibits significant potential as a DoD adhesive that functions at room temperature.

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    14
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  • Improvement in long-term stability of field effect transistor biosensor in aqueous environments using a combination of silane and reduced graphene oxide coating

    Sho Hideshima, Hiroki Hayashi, Ryo Takeuchi, Shofarul Wustoni, Shigeki Kuroiwa, Takuya Nakanishi, Toshiyuki Momma, Tetsuya Osaka

    Microelectronic Engineering   264   111859  2022.08  [Refereed]  [International journal]

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    9
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  • New Trends in Nanoarchitectured SERS Substrates: Nanospaces, 2D Materials, and Organic Heterostructures

    Olga Guselnikova, Hyunsoo Lim, Hyun Jong Kim, Sung Hyun Kim, Alina Gorbunova, Miharu Eguchi, Pavel Postnikov, Takuya Nakanishi, Toru Asahi, Jongbeom Na, Yusuke Yamauchi

    Small   18 ( 25 ) 2107182  2022.06  [Refereed]  [International journal]

    　View Summary

    This article reviews recent fabrication methods for surface-enhanced Raman spectroscopy (SERS) substrates with a focus on advanced nanoarchitecture based on noble metals with special nanospaces (round tips, gaps, and porous spaces), nanolayered 2D materials, including hybridization with metallic nanostructures (NSs), and the contemporary repertoire of nanoarchitecturing with organic molecules. The use of SERS for multidisciplinary applications has been extensively investigated because the considerably enhanced signal intensity enables the detection of a very small number of molecules with molecular fingerprints. Nanoarchitecture strategies for the design of new NSs play a vital role in developing SERS substrates. In this review, recent achievements with respect to the special morphology of metallic NSs are discussed, and future directions are outlined for the development of available NSs with reproducible preparation and well-controlled nanoarchitecture. Nanolayered 2D materials are proposed for SERS applications as an alternative to the noble metals. The modern solutions to existing limitations for their applications are described together with the state-of-the-art in bio/environmental SERS sensing using 2D materials-based composites. To complement the existing toolbox of plasmonic inorganic NSs, hybridization with organic molecules is proposed to improve the stability of NSs and selectivity of SERS sensing by hybridizing with small or large organic molecules.

    DOI PubMed

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    149
    Citation
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  • Glycan-immobilized dual-channel field effect transistor biosensor for the rapid identification of pandemic influenza viral particles

    Sho Hideshima, Hiroki Hayashi, Hiroshi Hinou, Shunsuke Nambuya, Shigeki Kuroiwa, Takuya Nakanishi, Toshiyuki Momma, Shin-Ichiro Nishimura, Yoshihiro Sakoda, Tetsuya Osaka

    Scientific Reports   9   11616  2019.08  [Refereed]  [International journal]

    DOI PubMed

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    35
    Citation
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  • Multianalyte detection of cancer biomarkers in human serum using label-free field effect transistor biosensor

    Ke Si, Shanshan Cheng, Sho Hideshima, Shigeki Kuroiwa, Takuya Nakanishi, Tetsuya Osaka

    Sensors and Materials   30 ( 5 ) 991 - 999  2018.05  [Refereed]  [International journal]

    　View Summary

    Recent statistics show that the incidence and mortality of cancer are on the rise. Among all types of cancer, lung cancer and liver cancer are the most prevalent. We have many biomarkers for these two cancers, among which the cytokeratin fragment 21-1 (CYFRA 21-1) and α-fetoprotein (AFP) are the most common and widely used. Among the various detection methods, the field effect transistor (FET) biosensor is one of the most attractive approaches, providing a label-free, fast, and low-cost electrical detection of biomarkers with high specificity and sensitivity. In previous work, we applied biomarkers for a single cancer type. With the detection of CYFRA 21-1 and neuron-specific enolase (NSE), lung cancer was differentiated in the early stages. Compared with the early work, the biomarkers for the two cancer types, CYFRA 21-1 for lung cancer and AFP for liver cancer, were prepared in this work. The detection of CYFRA 21-1 and AFP in human serum was achieved at the same time with the limits of detection of 1 and 10 ng mL−1, while the cut-off values were 4 and 10 ng mL−1. The method featured short analytical time, small sample volume, and low cost. With its good selectivity and appropriate sensitivity, clinical application will become popular in the future.

    DOI

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    14
    Citation
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  • Effect of human serum on the electrical detection of amyloid-β fibrils in biological environments using azo-dye immobilized field effect transistor (FET) biosensor

    Sho Hideshima, Shofarul Wustoni, Masumi Kobayashi, Hiroki Hayashi, Shigeki Kuroiwa, Takuya Nakanishi, Tetsuya Osaka

    Sensing and Bio-Sensing Research   17   25 - 29  2018.02  [Refereed]  [International journal]

    　View Summary

    As amyloid-β peptide 1–42 (Aβ42) was found to be an emerging and important biomarker for Alzheimer's disease, the detection of this peptide in biological samples such as human serum (HS) has become very important for evaluating the potential disease state and determining the appropriate treatment. In this study, we developed an electrical analysis strategy based on a field effect transistor (FET) biosensor as a simple and reliable technique for confirming the presence of Aβ42 aggregates (fibrils) in biological samples. By utilizing Congo red immobilized on the FET gate surface as a biorecognition element, we observed remarkable sensitivity and specificity for detecting Aβ42 fibrils. Furthermore, we optimized the procedure to minimize the interference of abundant human serum albumin for the detection system using HS samples. The optimized system of Congo red-immobilized FET enables measurement of Aβ42 fibrils in the 100-pM level in HS samples, which is lower than its clinical concentration. The FET device can be applied as a biosensing system for mass and routine screening of peptide biomarkers related to Alzheimer's disease.

    DOI

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    16
    Citation
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  • Label-free detection of allergens in food via surfactant-induced signal amplification using a field effect transistor-based biosensor

    Sho Hideshima, Mai Saito, Keisuke Fujita, Yoshitaka Harada, Mika Tsuna, Satoshi Sekiguchi, Shigeki Kuroiwa, Takuya Nakanishi, Tetsuya Osaka

    Sensors and Actuators B: Chemical   254   1011 - 1016  2018.01  [Refereed]  [International journal]

    　View Summary

    In recent years, food safety concerning food allergy has received increasing attention globally. A simple and sensitive detection method should be developed to measure trace amounts of allergens in foods. Here, we propose a label-free field effect transistor (FET)-based biosensing system for the detection of a buckwheat allergenic protein, BWp16, by surfactant-induced signal amplification. BWp16 could be detected by coupling with an anionic surfactant, sodium dodecyl sulfate (SDS), as this coupling enhanced the net charge of the protein, enough to be detected by FET biosensors. A significant response was observed when the allergen was coupled with SDS, while the responses were decreased or unchanged when it was coupled with a cationic or non-ionic surfactant, suggesting that the SDS coupling maintains the antibody recognition ability of the target allergen, and it would be useful to enhance the sensor responses. The fluorescence spectroscopic measurement revealed that the SDS molecules were successfully coupled with target allergenic protein BWp16, resulting in an increase in its net charge. Furthermore, we demonstrated that the FET biosensor enables specific detection of the allergen in food at the desired concentration levels for food safety analysis, suggesting that it could be used as an alternative food allergen analyzer, both industrially and domestically. (C) 2017 The Authors. Published by Elsevier B.V.

    DOI

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    34
    Citation
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  • Effective induction of death in mesothelioma cells with magnetite nanoparticles under an alternating magnetic field

    Shofu Matsuda, Eri Nakajima, Takuya Nakanishi, Airi Hitsuji, Hong Zhang, Akane Tanaka, Hiroshi Matsuda, Toshiyuki Momma, Tetsuya Osaka

    Materials Science and Engineering: C   81   90 - 96  2017.12  [Refereed]  [International journal]

    　View Summary

    With the objective of finding an avenue for development of magnetic hyperthermia as an effective mesothelioma treatment, the influence of heating by magnetite nanoparticles (MNPs) with a diameter of similar to 40 nm, which were incorporated into cells and then subjected to AC magnetic field, on induction of cell death was investigated in all three histological subtypes of human mesothelioma cells (i.e., epithelioid NCI-H28, sarcomatoid NCI-H2052, and biphasic MSTO-211H cells). Cellular uptake of MNPs was observed in all cell types, but the amount of MNPs incorporated per cell into MSTO-211H cells was smaller than in NCI-H28 and NCI-H2052 cells. On the other hand, cell death induced by cellular uptake of MNPs was observed specifically in MSTO-211H cells. Hence, when cells are heated by intracellular MNPs under AC magnetic field, a high degree of cell mortality in NCI-H28 and NCI-H2052 cells is induced by the temperature increase derived from the high amount of intracellular MNPs, but the combination of intracellular heating and cell-type-specific toxicity of MNPs induced high rates of cell death in MSTO-211H cells even at a lower temperature. Almost all of the heated cells were dead after 24-h incubation at 37 degrees C in all histological subtypes. Additionally, higher mortalities were observed in all three types of mesothelioma cells after MNPs-heating, as compared to the heating with a thermostatic bath. Herein, the significance of cellular uptake of MNPs for effectively inducing cell death in mesothelioma has been demonstrated in vitro. (C) 2017 Elsevier B.V. All rights reserved.

    DOI PubMed

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    9
    Citation
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  • Review of Physiological Balance Sensing in an Unobtrusive Manner

    Keishi Ohashi, Shigeki Kuroiwa, Sho Hideshima, Takuya Nakanishi, Tetsuya Osaka

    Electronics and Communications in Japan   100 ( 9 ) 50 - 55  2017.09

    　View Summary

    The concept of unobtrusive physiological balance sensing system implementing biosensors is discussed. Biosensors connected with a data system are expected to play a significant role when we extend the sensing objects from body to mind and spirit. Here, we describe the unobtrusive monitoring system using field effect transistor-type sensors and wireless communication devices. Substances subject to the survey of our research will include small ions, immunoglobulins, and hormones. (C) 2017 Wiley Periodicals, Inc.

    DOI

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    1
    Citation
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  • In Vitro Investigation of the Effect of Intracellular and Extracellular Magnetite Nanoparticles Subjected to Alternating Magnetic Field on MCF-7 Human Breast Cancer Cells

    Takuya Nakanishi, Shofu Matsuda, Kisako Kaneko, Hong Zhang, Tetsuya Osaka

    ChemistrySelect   1 ( 19 ) 6092 - 6102  2016.11  [Refereed]  [International journal]

    Authorship：Lead author

    　View Summary

    To evaluate the efficiency with which intra-and extracellular magnetite nanoparticles (MNPs) induce cell death under an alternating magnetic field (AMF), we comparatively investigated two systems consisting of MCF-7 human breast cancer cells and MNPs: one is a "simply-added" system, which is essentially a simple mixture of cells and extracellular MNPs, and the other is a "pre-cultivated" system that contains both intra-and extracellular MNPs. We also evaluated the effect of heating by thermostatic water bath (WB) on cell death in both systems. The degree of cell death was greater under heating with MNPs subjected to AMF than in the WB-heating in both systems. At higher doses of MNPs, the degree of cell death was greater in the "pre-cultivated" system than in the "simply-added" system using both heating methods. The cellular uptake of MNPs induced slight cell damage and caused a high degree of cell death at higher temperatures. A significant decrease in cell viability was observed in the presence of internalized MNPs under the AMF and was suggested to be a result of the combined effect of intracellular heating and cellular damage by MNPs.

    DOI

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    4
    Citation
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  • Theoretical Study on the Formation Mechanism of Amino Acid-Cu(II) Complexes on an Enantio-Sensing Device Interface

    Masahiro Kunimoto, Yusuke Sadaoka, Takuya Nakanishi, Tetsuya Osaka, Takayuki Homma

    The Journal of Physical Chemistry C   120 ( 29 ) 15722 - 15728  2016.07  [Refereed]  [International journal]

    　View Summary

    Theoretical analyses of L-alanine (L-Ala)- and L-homocysteine (L-Hcy)-Cu(II) complexes in basic, neutral, and acidic solutions were carried out using density functional theory to investigate the pH dependence of the formation mechanism of amino acid-Cu(II) complexes. The calculated complex formation energies indicate that the amino acid-Cu(II) complexes were expected to form in basic and neutral solutions but not in acidic solutions. The factors that determine the stability of these complexes are the coordination ability of each amino acid and the significance of intramolecular interactions among ligands within the complexes. As predicted from the molecular structure, in neutral solutions, the coordination ability of amino acid becomes lower than that in basic solutions because of the inert structure of the protonated amino group, -NH3+; however, the coordination ability originating from the -COO- group is estimated to be sufficient for stabilizing the entire complex system. Moreover, two H2O molecules coordinate with the central Cu2+ ion from the equatorial direction and interact with the coordinating amino acids, providing additional stability within the complex. In contrast, in acidic solutions, the complex does not have either sufficient coordination ability of amino acids or effective intramolecular interactions within the complex.

    DOI

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    3
    Citation
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  • Conversion of protein net charge via chemical modification for highly sensitive prion detection using field effect transistor (FET) biosensor

    Shofarul Wustoni, Sho Hideshima, Shigeki Kuroiwa, Takuya Nakanishi, Yasuro Mori, Tetsuya Osaka

    Sensors and Actuators B: Chemical   230   374 - 379  2016.07  [Refereed]  [International journal]

    　View Summary

    A robust and applicable strategy of signal amplification for field effect transistor (FET) biosensor is of scientifically and technologically importance to detect wide range of target molecules, particularly for the molecules of low charge density, and to configure highly sensitive analysis. In this communication, we demonstrate a simple technique to modify the net charge of target protein based on the concept of protein conjugation for the detection of prion, which is infectious and transmissible protein in neurodegenerative disorders. The increases of prion net charge after chemical modification generate signal amplification and have remarkably enhanced the sensitivity of FET biosensor below than femtomolar (fM) level. Thus, we suggest that such strategy is promising technique for achieving a highly sensitive detection at very low concentration that is useful for early determination of protein biomarkers. (C) 2016 Elsevier B.V. All rights reserved.

    DOI

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    5
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  • Signal amplification in electrochemical detection of buckwheat allergenic protein using field effect transistor biosensor by introduction of anionic surfactant

    Sho Hideshima, Keisuke Fujita, Yoshitaka Harada, Mika Tsuna, Yasuhiro Seto, Satoshi Sekiguchi, Shigeki Kuroiwa, Takuya Nakanishi, Tetsuya Osaka

    Sensing and Bio-Sensing Research   7   90 - 94  2016.03  [Refereed]  [International journal]

    　View Summary

    Food allergens, especially buckwheat proteins, sometimes induce anaphylactic shock in patients after ingestion. Development of a simple and rapid screening method based on a field effect transistor (FET) biosensor for food allergens in food facilities or products is in demand. In this study, we achieved the FET detection of a buckwheat allergenic protein (BWp16), which is not charged enough to be electrically detected by FET biosensors, by introducing additional negative charges from anionic surfactants to the target proteins. A change in the FET characteristics reflecting surface potential caused by the adsorption of target charged proteins was observed when the target sample was coupled with the anionic surfactant (sodium dodecyl sulfate
    SDS), while no significant response was detected without any surfactant treatment. It was suggested that the surfactant conjugated with the protein could be useful for the charge amplification of the target proteins. The surface plasmon resonance analysis revealed that the SDS-coupled proteins were successfully captured by the receptors immobilized on the sensing surface. Additionally, we obtained the FET responses at various concentrations of BWp16 ranging from 1 ng/mL to 10 μg/mL. These results suggest that a signal amplification method for FET biosensing is useful for allergen detection in the food industry.

    DOI

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    15
    Citation
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  • Review of physiological balance sensing in an unobtrusive manner

    Keishi Ohashi, Shigeki Kuroiwa, Sho Hideshima, Takuya Nakanishi, Tetsuya Osaka

    IEEJ Transactions on Sensors and Micromachines   136 ( 8 ) 357 - 361  2016  [Refereed]

    　View Summary

    The concept of unobtrusive physiological balance sensing system implementing biosensors is discussed. Biosensors connected with a data system is expected to play a significant role when we extend the sensing objects from body to mind and spirit. Here, we describe the unobtrusive monitoring system using FET-type sensors and wireless communication devices. Substances subject to the survey of our research will include small ions, immunoglobulins, and hormones.

    DOI

    Scopus

  • Induction of Cell Death in Mesothelioma Cells by Magnetite Nanoparticles

    Shofu Matsuda, Airi Hitsuji, Takuya Nakanishi, Hong Zhang, Akane Tanaka, Hiroshi Matsuda, Tetsuya Osaka

    ACS Biomaterials Science and Engineering   1 ( 8 ) 632 - 638  2015.12  [Refereed]  [International journal]

    　View Summary

    Nanoparticle uptake and cell death following addition of magnetite nanoparticles (MNPs) with a diameter of ∼10 nm were evaluated in three histological types of human mesothelioma cells, NCI-H28 (epithelioid), NCI-H2052 (sarcomatoid), and MSTO-211H (biphasic) cells, and human breast cancer MCF-7 cells. Dose-dependent cell death was observed in MSTO-211H cells but not in MCF-7 cells, although cellular uptake of MNPs was observed in both cell types. Mesothelioma NCI-H28 and NCI-H2052 cells showed behavior more similar to that of breast cancer MCF-7 cells than that of mesothelioma MSTO-211H cells. DNA fragmentation and microarray analyses suggested that MNPs induced transforming growth factor β2 related apoptosis in MSTO-211H cells. On the other hand, the viability of human mesothelioma cells containing MNPs with a diameter of ∼40 nm was investigated after exposure to an alternating magnetic field. Temperature increase under the alternating magnetic field and high rates of cell death were observed in all three histological types of human mesothelioma.

    DOI

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    10
    Citation
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  • Synthesis of cobalt ferrite nanoparticles using spermine and their effect on death in human breast cancer cells under an alternating magnetic field

    Shofu Matsuda, Takuya Nakanishi, Kisako Kaneko, Tetsuya Osaka

    Electrochimica Acta   183   153 - 159  2015.11  [Refereed]  [International journal]

    　View Summary

    To compare heat generation under an AC magnetic field for inducing cancer cell death, CoFe2O4 and Fe3O4 nanoparticles with a diameter of similar to 10 nm were synthesized by hydrolysis in an aqueous solution containing the metal chlorides iron(III) chloride and cobalt(II) or iron(II) chloride, with spermine or N,N'-bis(3-aminopropyl)butane-1,4-diamine, as a base and a protective reagent. Both CoFe2O4 and Fe3O4 nanoparticles were incorporated into human breast cancer MCF-7 cells; the nanoparticles exhibited little toxicity on the cells. When the cells containing nanoparticles were subjected to an AC magnetic field, MCF-7 cell death was induced by heat generated from similar to 10-nm CoFe2O4 nanoparticles but not from similar to 10-nm Fe3O4 nanoparticles. An increase in coercivity derived from the substitution of Fe2+ with Co2+ facilitated the ability of the nanoparticles to induce cell death in human breast cancer cells under an AC magnetic field. (C) 2015 Elsevier Ltd. All rights reserved.

    DOI

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    34
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  • Label-free detection of Cu(II) in a human serum sample by using a prion protein-immobilized FET sensor

    Shofarul Wustoni, Sho Hideshima, Shigeki Kuroiwa, Takuya Nakanishi, Yasuro Mori, Tetsuya Osaka

    Analyst   140 ( 19 ) 6485 - 6488  2015.10  [Refereed]  [International journal]

    　View Summary

    We have developed a field effect transistor (FET) sensor to sensitively detect copper ions (Cu2+) in a human serum (HS) sample for promising health-care diagnosis. By utilizing a Cu2+-binding prion protein that was immobilized on the FET gate surface, such an FET sensor can provide a simple, label free and highly selective performance, even in HS samples. We demonstrated the sensitivity of the sensor at the nanomolar level, 0-100 nM, which is very useful for the detection range of Cu2+ deficiency in practical applications.

    DOI

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    17
    Citation
    (Scopus)

  • Label-free detection of tumor markers using field effect transistor (FET)-based biosensors for lung cancer diagnosis

    Shanshan Cheng, Sho Hideshima, Shigeki Kuroiwa, Takuya Nakanishi, Tetsuya Osaka

    Sensors and Actuators B: Chemical   212   329 - 334  2015.06  [Refereed]  [International journal]

    　View Summary

    Detection of tumor markers is important for cancer diagnosis. Field effect transistor (FET) has been recognized as a powerful technique for label-free, sensitive, real-time, and multifunctional biosensing. Here, we developed FET biosensors that allow the label-free detection of cytokeratin fragment 21-1 (CYFRA 21-1) and neuron-specific enolase (NSE), useful tumor markers for lung cancer type differentiation. It was found that the FET biosensor was capable of quantitatively detecting these tumor markers in both phosphate-buffered saline and human serum. Additionally, we developed a multianalyte FET biosensor for the selective multiplexed detection of CYFRA 21-1 and NSE at the same time, by integrating two antibody types on the same chip, providing a step towards the realization of sensor arrays. The multianalyte FET biosensor, as described herein, will help for lung cancer differential diagnosis with advantages of simple and rapid detection procedures, low sample consumption, and low cost. (C) 2015 Elsevier B.V. All rights reserved.

    DOI

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    146
    Citation
    (Scopus)

  • Sensitive electrical detection of human prion proteins using field effect transistor biosensor with dual-ligand binding amplification

    Shofarul Wustoni, Sho Hideshima, Shigeki Kuroiwa, Takuya Nakanishi, Masahiro Hashimoto, Yasuro Mori, Tetsuya Osaka

    Biosensors and Bioelectronics   67   256 - 262  2015.05  [Refereed]  [International journal]

    　View Summary

    Simple and accurate detection of prion proteins in biological samples is of utmost importance in recent years. In this study, we developed a label-free electrical detection-based field effect transistor (FET) biosensor using thiamine as a probe molecule for a non-invasive and specific test of human prion protein detection. We found that thiamine-immobilized FETs can be used to observe the prion protein oligomer, and might be a significant test for the early diagnosis of prion-related diseases. The thiamine-immobilized FET was also demonstrated for the detection of prion proteins in blood serum without any complex pre-treatments. Furthermore, we designed a dual-ligand binding approach by the addition of metal ions as a second ligand to bind with the adsorbed prion protein on the thiamine-immobilized surface. When the prion attached to metal ions, the additional positive charge was induced on the gate surface of the FET. This approach was capable of amplifying the magnitude of the FET response and of enhancing the sensitivity of the FET biosensor. Detection of prion proteins has achieved the required concentration for clinical diagnosis in blood serum, which is less than 2 nM. In summary, this FET biosensor was successfully applied to prion detection and proved useful as a simple, fast, sensitive and low-cost method towards a mass-scale and routine blood screening-based test. (C) 2014 Elsevier B.V. All rights reserved.

    DOI

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    31
    Citation
    (Scopus)

  • Effects of chemical treatment of indium tin oxide electrode on its surface roughness and work function

    Md. Zaved Hossain Khan, Takuya Nakanishi, Tetsuya Osaka

    Surface and Coatings Technology   244   189 - 193  2014.04  [Refereed]  [International journal]

    Authorship：Lead author

    　View Summary

    In this paper, we report the effects of chemical treatment of indium tin oxide (ITO) surface on its surface chemistry such as chemical composition and surface roughness and on its usage as an electrode with monolayer modification. Atomic force microscopy, angel-resolved X-ray photoelectron spectroscopy, and Kelvin probe force microscopy have been used to investigate the morphology and the chemical properties of commercial thin ITO films after several treatments commonly used prior to the formation of organic layer on the surface. The amount of spike present on the surface of as-received ITO substrates was significantly reduced by etching with KOH whereas the roughness of ITO increased with HCI etching. We demonstrated that the successive treatment of ITO electrode with HCI and KOH affects the surface characteristics such as roughness and work function, contributing to the potentiometric detection of tiyptophan. (C) 2014 Elsevier B.V. All rights reserved.

    DOI

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    14
    Citation
    (Scopus)

  • Field Effect Transistor Biosensor Using Antigen Binding Fragment for Detecting Tumor Marker in Human Serum

    Shanshan Cheng, Kaori Hotani, Sho Hideshima, Shigeki Kuroiwa, Takuya Nakanishi, Masahiro Hashimoto, Yasuro Mori, Tetsuya Osaka

    Materials   7 ( 4 ) 2490 - 2500  2014.04  [Refereed]  [International journal]

    　View Summary

    Detection of tumor markers is important for cancer diagnosis. Field-effect transistors (FETs) are a promising method for the label-free detection of trace amounts of biomolecules. However, detection of electrically charged proteins using antibody-immobilized FETs is limited by ionic screening by the large probe molecules adsorbed to the transistor gate surface, reducing sensor responsiveness. Here, we investigated the effect of probe molecule size on the detection of a tumor marker, alpha-fetoprotein (AFP) using a FET biosensor. We demonstrated that the small receptor antigen binding fragment (Fab), immobilized on a sensing surface as small as 2-3 nm, offers a higher degree of sensitivity and a wider concentration range (100 pg/mL-1 mu g/mL) for the FET detection of AFP in buffer solution, compared to the whole antibody. Therefore, the use of a small Fab probe molecule instead of a whole antibody is shown to be effective for improving the sensitivity of AFP detection in FET biosensors. Furthermore, we also demonstrated that a Fab-immobilized FET subjected to a blocking treatment, to avoid non-specific interactions, could sensitively and selectively detect AFP in human serum.

    DOI

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    77
    Citation
    (Scopus)

  • Effect of Synthetic Quartz Nanoparticle-Supported Counter Electrode on Dye-Sensitized Solar Cell

    Shigeki Kuroiwa, Atsushi Kyan, Tomoko Ito, Nobuaki Komatsu, Takuya Nakanishi, Tetsuya Osaka

    Electrochemistry   82 ( 3 ) 165 - 167  2014.03  [Refereed]  [International journal]

    DOI

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  • A label-free electrical assay of fibrous amyloid beta based on semiconductor biosensing

    Sho Hideshima, Masumi Kobayashi, Takeyoshi Wada, Shigeki Kuroiwa, Takuya Nakanishi, Naoya Sawamura, Toru Asahi, Tetsuya Osaka

    Chemical Communications   50 ( 26 ) 3476 - 3479  2014.03  [Refereed]  [International journal]

    　View Summary

    We propose, as an alternative to conventional spectroscopic assays, a simple method for discriminating fibrous amyloid proteins by using a label-free semiconductor-based biosensor. The highly sensitive assay is expected to be useful for accelerating amyloid related research.

    DOI

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    15
    Citation
    (Scopus)

  • Monitoring Amyloid Sup35NM Growth with Label-Free Electrical Detection Using a Field-Effect Transistor Biosensor

    Sho Hideshima, Shofarul Wustoni, Shigeki Kuroiwa, Takuya Nakanishi, Ayumi Koike-Takeshita, Tetsuya Osaka

    ChemElectroChem   1 ( 1 ) 51 - 54  2014.01  [Refereed]  [International journal]

    DOI

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    3
    Citation
    (Scopus)

  • Attomolar Detection of Influenza A Virus Hemagglutinin Human H1 and Avian H5 Using Glycan-Blotted Field Effect Transistor Biosensor

    Sho Hideshima, Hiroshi Hinou, Daisuke Ebihara, Ryosuke Sato, Shigeki Kuroiwa, Takuya Nakanishi, Shin-Ichiro Nishimura, Tetsuya Osaka

    Analytical Chemistry   85 ( 12 ) 5641 - 5644  2013.06  [Refereed]  [International journal]

    　View Summary

    Influenza virus, through cell invasion and propagation with the interaction between hemagglutinin (HA) present on its surface and glycans on the host cell, causes a rapidly spreading infection throughout the world. In the present investigation, we succeeded for the first time in the attomolar-level sensing and discrimination of influenza A viral HA molecules H1 and H5 by using a glycan-immobilized field effect transistor (FET) biosensor. The small ligand glycans immobilized on the FET device, which make effective use of the charge-detectable region for FET-based detection in terms of Debye length, gave an advantage in the highly sensitive detection of the proteins. Two kinds of trisaccharides receptors terminating in sialic acid-alpha 2,6-galactose (6'-sialyllactose) and in sialic acid-alpha 2,3-galactose (3'-sialyllactose) were conjugated directly with the SiO2 surface of FET devices by a simple glycoblotting method using the self-assembled monolayer (SAM) of aminooxy terminated silane-coupling reagent, 3-aminooxypropyltriethoxysilane. Furthermore, it was demonstrated that the FETs with densely immobilized glycans, which possess the high capture ability by achieving the glycoside cluster effect, clearly distinguish HA molecules between their subtypes H1 (human) and H5 (avian) at the attomolar level, while the conventional method based on HA antibodies achieves only picomolar-level detection. Our findings indicate that the glycan-immobilized FET is a promising device to detect various pathogenic bacteria and viruses through glycan-protein interaction found ubiquitously in many infectious diseases.

    DOI

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    109
    Citation
    (Scopus)

  • Cytotoxicity evaluation of magnetite (Fe3O4) nanoparticles in mouse embryonic stem cells

    Chigusa Shundo, Hong Zhang, Takuya Nakanishi, Tetsuya Osaka

    Colloids and Surfaces B: Biointerfaces   97   221 - 225  2012.09  [Refereed]  [International journal]

    DOI

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    44
    Citation
    (Scopus)

  • Detection of Matrix Metalloproteinase-2 by Field Effect Transistor with a Fibronectin-immobilized Gate

    Daisuke Yamamoto, Sho Hideshima, Shigeki Kuroiwa, Takuya Nakanishi, Tetsuya Osaka

    Chemistry Letters   41 ( 8 ) 825 - 827  2012.08  [Refereed]  [International journal]

    DOI

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    2
    Citation
    (Scopus)

  • Effect of magnetite nanoparticles on living rate of MCF-7 human breast cancer cells

    Daisuke Baba, Yasuhiro Seiko, Takuya Nakanishi, Hong Zhang, Atsushi Arakaki, Tadashi Matsunaga, Tetsuya Osaka

    Colloids and Surfaces B: Biointerfaces   95   254 - 257  2012.06  [Refereed]  [International journal]

    DOI

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    34
    Citation
    (Scopus)

  • Chiral sensing system based on the formation of diastereomeric metal complex on a homocysteine monolayer using field effect transistor

    Daisuke Yamamoto, Takuya Nakanishi, Tetsuya Osaka

    Electrochimica Acta   56 ( 26 ) 9652 - 9655  2011.11  [Refereed]  [International journal]

    DOI CiNii

    Scopus

    10
    Citation
    (Scopus)

  • Effect of surface roughness and surface modification of indium tin oxide electrode on its potential response to tryptophan

    Md. Zaved Hossain Khan, Takuya Nakanishi, Shigeki Kuroiwa, Yoichi Hoshi, Tetsuya Osaka

    Electrochimica Acta   56 ( 24 ) 8657 - 8661  2011.10  [Refereed]  [International journal]

    DOI CiNii

    Scopus

    11
    Citation
    (Scopus)

  • Potentiometric Detection of Serotonin, Melatonin, and Their Precursors/Metabolites with Monolayer-Modified Indium Tin Oxide Electrode and Their Concentration Dependency

    Md. Zaved Hossain Khan, Takuya Nakanishi, Tetsuya Osaka

    Sensor Letters   9 ( 5 ) 1849 - 1852  2011.10  [Refereed]  [International journal]

    DOI

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    9
    Citation
    (Scopus)

  • Chiral discrimination between alanine enantiomers by field effect transistor with a homocysteine monolayer-modified gate

    Mariko Matsunaga, Daisuke Yamamoto, Takuya Nakanishi, Tetsuya Osaka

    Electrochimica Acta   55 ( 15 ) 4501 - 4505  2010.06  [Refereed]  [International journal]

    DOI CiNii

    Scopus

    20
    Citation
    (Scopus)

  • Potential Response of Monolayer-Modified Indium Tin Oxide Electrodes to Indole Compounds

    Takuya Nakanishi, Tsubasa Ueno, Mariko Matsunaga, Md. Zaved Hossain Khan, Tetsuya Osaka

    Electroanalysis   22 ( 4 ) 393 - 398  2010.02  [Refereed]  [International journal]

    Authorship：Lead author

    DOI CiNii

    Scopus

    10
    Citation
    (Scopus)

  • New Proposal for the Interfacial Design toward the Establishment of Electrochemical Device Engineering

    Tetsuya Osaka, Takuya Nakanishi

    ELECTROCHEMICAL ENGINEERING FOR THE 21ST CENTURY (DEDICATED TO RICHARD C. ALKIRE)   28 ( 29 ) 17 - 24  2010  [Refereed]  [International journal]

    DOI

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  • Effect of surface charge of magnetite nanoparticles on their internalization into breast cancer and umbilical vein endothelial cells

    Tetsuya Osaka, Takuya Nakanishi, Sangaraju Shanmugam, Shintaro Takahama, Hong Zhang

    Colloids and Surfaces B: Biointerfaces   71 ( 2 ) 325 - 330  2009.07  [Refereed]  [International journal]

    DOI PubMed CiNii

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    153
    Citation
    (Scopus)

  • Biosensing by optical waveguide spectroscopy based on localized surface plasmon resonance of gold nanoparticles used as a probe or as a label

    Mayuki Kajiura, Takuya Nakanishi, Hironori Iida, Harumi Takada, Tetsuya Osaka

    Journal of Colloid and Interface Science   335 ( 1 ) 140 - 145  2009.07  [Refereed]  [International journal]

    DOI PubMed CiNii

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    29
    Citation
    (Scopus)

  • Tb3+-enhanced Potentiometric Detection of Single Nucleotide Polymorphism by Field Effect Transistors

    Jinping Wang, Kenya Ito, Takuya Nakanishi, Shigeki Kuroiwa, Tetsuya Osaka

    Chemistry Letters   38 ( 4 ) 376 - 377  2009.04  [Refereed]  [International journal]

    DOI CiNii

    Scopus

    6
    Citation
    (Scopus)

  • Controlled synthesis and magnetic properties of iron oxide nanostructures using biogenic polyamines

    Sangaraju Shanmugam, Takuya Nakanishi, Tetsuya Osaka

    ECS Transactions   16 ( 45 ) 189 - 197  2009  [Refereed]  [International journal]

    DOI

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    6
    Citation
    (Scopus)

  • Morphology and Magnetic Properties of Iron Oxide Nanostructures Synthesized with Biogenic Polyamines

    Sangaraju Shanmugam, Takuya Nakanishi, Tetsuya Osaka

    Journal of The Electrochemical Society   156 ( 7 ) K121 - K127  2009  [Refereed]  [International journal]

    DOI CiNii

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    8
    Citation
    (Scopus)

  • Preparation of Human Immune Effector T Cells Containing Iron-Oxide Nanoparticles

    Hironori Iida, Kosuke Takayanagi, Takuya Nakanishi, Akiko Kume, Kouji Muramatsu, Yoshio Kiyohara, Yasuto Akiyama, Tetsuya Osaka

    Biotechnology and Bioengineering   101 ( 6 ) 1123 - 1128  2008.12  [Refereed]  [International journal]

    DOI PubMed CiNii

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    16
    Citation
    (Scopus)

  • Enantioselective potential response of a human serum albumin-modified ITO electrode for tryptophan

    Mariko Matsunaga, Tsubasa Ueno, Takuya Nakanishi, Tetsuya Osaka

    Electrochemistry Communications   10 ( 12 ) 1844 - 1846  2008.12  [Refereed]  [International journal]

    DOI CiNii

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    24
    Citation
    (Scopus)

  • Preparation of FePt Nanoparticles with a Narrow Size Distribution in Ionic Liquids

    Tetsuya Osaka, Takuma Hachisu, Atsushi Sugiyama, Izumi Kawakita, Takuya Nakanishi, Hironori Iida

    Chemistry Letters   37 ( 10 ) 1034 - 1035  2008.10  [Refereed]  [International journal]

    DOI CiNii

    Scopus

    9
    Citation
    (Scopus)

  • Stereospecificity in redox reactions of catechins at gold electrodes modified with self-assembled monolayers of homocysteine

    Takuya Nakanishi, Mariko Matsunaga, Makoto Nagasaka, Tsubasa Ueno, Tetsuya Osaka

    Electrochimica Acta   53 ( 21 ) 6209 - 6214  2008.09  [Refereed]  [International journal]

    Authorship：Lead author

    DOI

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    14
    Citation
    (Scopus)

  • Effect of growth temperature on the shape and crystallinity of chemically produced FePt nanoparticles

    Takuma Hachisu, Takahiro Yotsumoto, Atsushi Sugiyama, Hironori Iida, Takuya Nakanishi, Toru Asahi, Tetsuya Osaka

    Chemistry Letters   37 ( 8 ) 840 - 841  2008.08  [Refereed]  [International journal]

    DOI CiNii

    Scopus

    9
    Citation
    (Scopus)

  • Effect of pH on the enantiospecificity of homocysteine monolayer on Au(111) for the redox reaction of 3,4-dihydroxyphenylalanine

    Mariko Matsunaga, Makoto Nagasaka, Takuya Nakanishi, Takahiro Sawaguchi, Tetsuya Osaka

    Electroanalysis   20 ( 9 ) 955 - 962  2008.05  [Refereed]  [International journal]

    DOI CiNii

    Scopus

    15
    Citation
    (Scopus)

  • Immobilization of gold nanoparticles on optical waveguides with organosilane monolayer

    Takuya Nakanishi, Harumi Takada, Hironori Iida, Mayuki Kajiura, Tetsuya Osaka

    Colloids and Surfaces A: Physicochemical and Engineering Aspects   313   234 - 238  2008.02  [Refereed]  [International journal]

    Authorship：Lead author

    DOI

    Scopus

    2
    Citation
    (Scopus)

  • Organic molecular sensor with plasmon antenna

    Masahiro Yanagisawa, Naonobu Shimamoto, Takuya Nakanishi, Mikiko Saito, Tetsuya Osaka

    ECS Transactions   16 ( 11 ) 397 - 409  2008  [Refereed]  [International journal]

    DOI

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    8
    Citation
    (Scopus)

  • Synthesis of Fe3O4 nanoparticles with various sizes and magnetic properties by controlled hydrolysis

    Hironori Iida, Kosuke Takayanagi, Takuya Nakanishi, Tetsuya Osaka

    Journal of Colloid and Interface Science   314 ( 1 ) 274 - 280  2007.10  [Refereed]  [International journal]

    DOI PubMed CiNii

    Scopus

    450
    Citation
    (Scopus)

  • Effect of surface coverage of gold(111) electrode with cysteine on the chiral discrimination of DOPA

    Mariko Matsunaga, Takuya Nakanishi, Toru Asahi, Tetsuya Osaka

    Chirality   19 ( 4 ) 295 - 299  2007.05  [Refereed]  [International journal]

    DOI

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    23
    Citation
    (Scopus)

  • Highly enantioselective discrimination of amino acids using copper deposition on a gold electrode modified with homocysteine monolayer

    Mariko Matsunaga, Takuya Nakanishi, Toru Asahi, Tetsuya Osaka

    Electrochemistry Communications   9 ( 4 ) 725 - 728  2007.04  [Refereed]  [International journal]

    DOI CiNii

    Scopus

    33
    Citation
    (Scopus)

  • Origin of chiral discrimination by a two-dimensionally chiral self-assembled monolayer: A quantum chemical study

    Tomohiro Nishikawa, Tsukasa Torimoto, Takuya Nakanishi, Tetsuya Osaka, Bunsho Ohtani

    Chemical Physics Letters   432 ( 4-6 ) 502 - 507  2006.12  [Refereed]  [International journal]

    DOI CiNii

    Scopus

    2
    Citation
    (Scopus)

  • Preparation of magnetic iron-oxide nanoparticles by successive reduction-oxidation in reverse micelles: Effects of reducing agent and atmosphere

    Hironori Iida, Takuya Nakanishi, Harumi Takada, Tetsuya Osaka

    Electrochimica Acta   52 ( 1 ) 292 - 296  2006.10  [Refereed]  [International journal]

    DOI CiNii

    Scopus

    29
    Citation
    (Scopus)

  • Enantioselectivity of redox reaction of DOPA at the gold electrode modified with a self-assembled monolayer of homocysteine

    Takuya Nakanishi, Mariko Matsunaga, Makoto Nagasaka, Toru Asahi, Tetsuya Osaka

    Journal of the American Chemical Society   128 ( 41 ) 13322 - 13323  2006.10  [Refereed]  [International journal]

    Authorship：Lead author, Corresponding author

    DOI PubMed CiNii

    Scopus

    55
    Citation
    (Scopus)

  • Crystallization of leucine on a self-assembled monolayer with covalently attached enantiomeric leucine molecules

    Takuya Nakanishi, Naoki Banno, Mariko Matsunaga, Toru Asahi, Tetsuya Osaka

    Colloids and Surfaces A: Physicochemical and Engineering Aspects   284   270 - 275  2006.08  [Refereed]  [International journal]

    Authorship：Lead author, Corresponding author

    DOI

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    12
    Citation
    (Scopus)

  • Effect of substrate morphology on the crystallization of leucine on gold surface modified with a self-assembled monolayer

    Tetsuya Osaka, Mariko Matsunaga, Takuya Nakanishi, Toru Asahi, Naoki Banno

    Chemistry Letters   35 ( 4 ) 438 - 439  2006.04  [Refereed]  [International journal]

    DOI CiNii

    Scopus

    3
    Citation
    (Scopus)

  • A Novel Approach for Preparation of gamma-Fe2O3 Nanoparticles: Successive Reduction-Oxidation in Reverse Micelles

    Hironori Iida, Harumi Takada, Takuya Nakanishi, Tetsuya Osaka

    The Electrochemical Society Proceeding Volumes   PV 2004-23   325 - 329  2006  [Refereed]  [International journal]

    　View Summary

    A novel approach for the preparation of γ-Fe2O3 nanoparticles based on successive reduction-oxidation in reverse micelles is reported. In this method, γ-Fe2O3 nanoparticles are formed via chemical reduction of ferrous or ferric ions by a reducing agent such as NaBH4, N2H4, or NaH2PO 2, followed by successive oxidation in reverse micelles. The generation of nanoparticles is caused by the "electroless deposition" in reverse micelles, and it was found that the crystal structure and the magnetic properties of the products depend on the redox potential of the reducing agent and the catalytic activity of the metal surface. In the case using NaBH4 as a reducing agent, highly crystalline γ-Fe 2O3 nanoparticles were successfully synthesized.

  • Application of a Two-phase Liquid-Liquid System to the Synthesis of Iron-Containing Nanoparticles

    Takuya Nakanishi, Hironori Iida, Harumi Takada, Tetsuya Osaka

    The Electrochemical Society Proceeding Volumes   PV 2004-23   330 - 335  2006  [Refereed]  [International journal]

    Authorship：Lead author

    　View Summary

    As a novel approach to the preparation of iron nanoparticles, a two-phase liquid-liquid system was applied. Efficient transfer of iron(III) species from aqueous solution to toluene as tetrachloroferrate(III) was found to depend on the presence of hydrochloric acid. In the reduction process, the addition of dodecanethiol to toluene resulted in the suppression of the excessive growth of oxides or hydroxides. The dominant phase was a-Fe, and the magnetic properties of the product were suggested to reflect the presence of a γ-Fe 2O3 (or Fe3O4) subphase.

  • Synthesis of magnetic nanoparticles and their application to bioassays

    Tetsuya Osaka, Tadashi Matsunaga, Takuya Nakanishi, Atsushi Arakaki, Daisuke Niwa, Hironori Iida

    Analytical and Bioanalytical Chemistry   384 ( 3 ) 593 - 600  2006.01  [Refereed]  [International journal]

    　View Summary

    Magnetic nanoparticles have been attracting much interest as a labeling material in the fields of advanced biological and medical applications such as drug delivery, magnetic resonance imaging, and array-based assaying. In this review, synthesis of iron oxide magnetic nanoparticles via a reverse micelle system and modification of their surface by an organosilane agent are discussed. Furthermore, as a practical biological assay system, the magnetic detection of biomolecular interactions is demonstrated by using the combination of a patterned substrate modified with a self-assembled monolayer and the magnetic nanoparticles.

    DOI PubMed

    Scopus

    186
    Citation
    (Scopus)

  • Surface modification of gamma-Fe2O3 nanoparticles with aminopropylsilyl groups and interparticle linkage with alpha,omega-dicarboxylic acids

    Hironori Iida, Takuya Nakanishi, Tetsuya Osaka

    Electrochimica Acta   51 ( 5 ) 855 - 859  2005.11  [Refereed]  [International journal]

    DOI

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    33
    Citation
    (Scopus)

  • Effects of additives on copper electrodeposition in submicrometer trenches

    Madoka Hasegawa, Yoshinori Negishi, Takuya Nakanishi, Tetsuya Osaka

    Journal of The Electrochemical Society   152 ( 4 ) C221 - C228  2005  [Refereed]  [International journal]

    DOI CiNii

    Scopus

    107
    Citation
    (Scopus)

  • Enantioselective crystal growth of leucine on a self-assembled monolayer with covalently attached leucine molecules

    Naoki Banno, Takuya Nakanishi, Mariko Matsunaga, Toru Asahi, Tetsuya Osaka

    Journal of the American Chemical Society   126 ( 2 ) 428 - 429  2004.01  [Refereed]  [International journal]

    Authorship：Corresponding author

    DOI PubMed CiNii

    Scopus

    52
    Citation
    (Scopus)

  • Chiral discrimination between thalidomide enantiomers using a solid surface with two-dimensional chirality

    Takuya Nakanishi, Naoko Yamakawa, Toru Asahi, Norio Shibata, Bunsho Ohtani, Tetsuya Osaka

    Chirality   16 ( S1 ) S36 - S39  2004  [Refereed]  [International journal]

    Authorship：Lead author, Corresponding author

    DOI

    Scopus

    45
    Citation
    (Scopus)

  • Preparation of iron oxide nanoparticles via successive reduction-oxidation in reverse micelles

    Takuya Nakanishi, Hironori Iida, Tetsuya Osaka

    Chemistry Letters   32 ( 12 ) 1166 - 1167  2003.12  [Refereed]  [International journal]

    Authorship：Lead author, Corresponding author

    DOI CiNii

    Scopus

    31
    Citation
    (Scopus)

  • Influence of carbon inclusion on properties of electrodeposited CoNiFeMo thin films

    Tokihiko Yokoshima, Asako Kawashima, Takuya Nakanishi, Tetsuya Osaka, Mikiko Saito, Keishi Ohashi

    The Electrochemical Society Proceeding Volumes   PV 2002-27   365 - 375  2003  [Refereed]  [International journal]

  • Thermal desorption high-resolution mass spectrometry of mixed self-assembled monolayers on gold

    Toshimichi Shibue, Takuya Nakanishi, Tomoka Matsuda, Toru Asahi, Tetsuya Osaka

    Langmuir   18 ( 5 ) 1528 - 1534  2002.03  [Refereed]  [International journal]

    DOI CiNii

    Scopus

    13
    Citation
    (Scopus)

  • Enantioselective adsorption of phenylalanine onto self-assembled monolayers of 1,1 '-binaphthalene-2,2 '-dithiol on gold

    Takuya Nakanishi, Naoko Yamakawa, Toru Asahi, Tetsuya Osaka, Bunsho Ohtani, Kohei Uosaki

    Journal of the American Chemical Society   124 ( 5 ) 740 - 741  2002.02  [Refereed]  [International journal]

    Authorship：Lead author

    DOI PubMed CiNii

    Scopus

    42
    Citation
    (Scopus)

  • All-Wet Barrier-Layer Fabricating Process on SiO2 for ULSI Cu Interconnections

    Tetsuya Osaka, Tokihiko Yokoshima, Takuya Nakanishi

    Proceedings of the Second International Conference on Semiconductor Technology     324 - 332  2002  [Refereed]  [International journal]

  • Pulsed electrodeposition of nanocrystalline CoNiFe soft magnetic thin films

    Takuya Nakanishi, Masaki Ozaki, Hyo-Seung Nam, Tokihiko Yokoshima, Tetsuya Osaka

    Journal of The Electrochemical Society   148 ( 9 ) C627 - C631  2001.09  [Refereed]  [International journal]

    Authorship：Lead author

    DOI CiNii

    Scopus

    52
    Citation
    (Scopus)

  • Effects of impurities on resistivity of electrodeposited high-B-s CoNiFe-based soft magnetic thin films

    Tetsuya Osaka, Tokihiko Yokoshima, Takuya Nakanishi

    IEEE Transactions on Magnetics   37 ( 4 ) 1761 - 1763  2001.07  [Refereed]  [International journal]

    DOI CiNii

    Scopus

    15
    Citation
    (Scopus)

  • Microstructure of electroplated soft magnetic CoNiFe thin films

    Hyo-Seung Nam, Tokihiko Yokoshima, Takuya Nakanishi, Tetsuya Osaka, Yohtaro Yamazaki, Dong Nyung Lee

    Thin Solid Films   384 ( 2 ) 288 - 293  2001.03  [Refereed]  [International journal]

    DOI CiNii

    Scopus

    44
    Citation
    (Scopus)

  • Fabrication of High-Bs Soft Magnetic Thin Film by an Electrodeposition Technique for Next-Generation Magnetic Recording Field

    Tetsuya Osaka, Tokihiko Yokoshima, Takuya Nakanishi

    The Electrochemical Society Proceeding Volumes   PV 2000-29   167 - 175  2001  [Refereed]  [International journal]

  • Pulsed Electrodeposition of Soft Magnetic CoNiFe Thin Films

    Takuya Nakanishi, Masaki Ozaki, Hyo-Seung Nam, Tokihiko Yokoshima, Tetsuya Osaka

    The Electrochemical Society Proceeding Volumes   PV 2000-29   176 - 184  2001  [Refereed]  [International journal]

    Authorship：Lead author

  • High-frequency permeability and thermal stability of electrodeposited high-B-s CoNiFe thin films

    Satoshi Mizutani, Tokihiko Yokoshima, Hyo-Seung Nam, Takuya Nakanishi, Tetsuya Osaka, Yohtaro Yamazaki

    IEEE Transactions on Magnetics   36 ( 5 ) 2539 - 2541  2000.09  [Refereed]  [International journal]

    DOI CiNii

    Scopus

    11
    Citation
    (Scopus)

  • Preparation and characterization of electrodeposited high-B-s CoNiFe thin films with high resistivity and improvement of their corrosion resistance

    Manabu Kaseda, Masahiro Yamada, Takuya Nakanishi, Tetsuya Osaka

    The Electrochemical Society Proceeding Volumes   PV 99-34   263 - 272  2000  [Refereed]  [International journal]

  • Preparation of Electrodeposited High-B_s and High-ρ CoNiFe Thin Films by Mo Addition

    SOGAWA Y., KAWASHIMA A., YOKOSHIMA T., NAKANISHI T., NAM H.-S., OSAKA T., OHASHI K.

    Journal of the Magnetics Society of Japan   24 ( 4-2 ) 699 - 702  2000  [Refereed]

    DOI CiNii

  • Increasing the resistivity of electrodeposited high B-S CoNiFe thin film

    Tokihiko Yokoshima, Manabu Kaseda, Masahiro Yamada, Takuya Nakanishi, Toshiyuki Momma, Tetsuya Osaka

    IEEE Transactions on Magnetics   35 ( 5 ) 2499 - 2501  1999.09  [Refereed]  [International journal]

    DOI CiNii

    Scopus

    25
    Citation
    (Scopus)

  • Structure and photoelectrochemical properties of laminated monoparticle layers of CdS and ZnS on gold

    Takuya Nakanishi, Bunsho Ohtani, Kohei Uosaki

    Japanese Journal of Applied Physics   38 ( 1B ) 518 - 521  1999.01  [Refereed]  [International journal]

    Authorship：Lead author

    DOI CiNii

    Scopus

    22
    Citation
    (Scopus)

  • Effect of immobilized electron relay on the interfacial photoinduced electron transfer at a layered inorganic-organic composite film on gold

    Takuya Nakanishi, Bunsho Ohtani, Kohei Uosaki

    Journal of Electroanalytical Chemistry   455 ( 1-2 ) 229 - 234  1998.09  [Refereed]  [International journal]

    Authorship：Lead author

    DOI

    Scopus

    20
    Citation
    (Scopus)

  • Redox potential of Mo(VI)/Mo in alkali borate melts

    Takuya Nakanishi, Hideki Maekawa, Toshio Yokokawa

    Materials Transactions, JIM   39 ( 3 ) 399 - 403  1998.03  [Refereed]  [International journal]

    Authorship：Lead author

    DOI

    Scopus

    7
    Citation
    (Scopus)

  • Fabrication and Characterization of CdS-Nanoparticle Mono- and Multilayers on a Self-Assembled Monolayer of Alkanedithiols on Gold

    Takuya Nakanishi, Bunsho Ohtani, Kohei Uosaki

    The Journal of Physical Chemistry B   102 ( 9 ) 1571 - 1577  1998.02  [Refereed]  [International journal]

    Authorship：Lead author

    　View Summary

    Mono- and multilayers of cadmium sulfide (CdS) nanoparticles were fabricated on a gold substrate covered with alkanedithiol self-assembled monolayers (SAMs) by an alternate immersion of the substrate into ethanolic solutions of dithiol, i.e., 1,6-hexanedithiol or 1,10-decanedithiol, and dispersion of CdS nanoparticles (ca. 3 nm in diameter), the latter of which was prepared in sodium bis(2-ethylhexyl)sulfosuccinate (Aerosol OT, AOT)/H2O/heptane reversed micelles. A layer-by-layer structure of dithiol SAM and CdS monolayer was confirmed with Fourier transform infrared reflection - absorption spectroscopy (FT-IRRAS) and X-ray photoelectron spectroscopy (XPS) at each step of composite-film preparation. It was revealed that CdS nanoparticles on SAMs were surrounded by AOT, which was then substituted by dithiols when the film was treated with the dithiol solution. The amount of CdS nanoparticles on the sample was measured by inductively coupled plasma mass spectrometry (ICP-MS) to be consistent with the above-mentioned monolayer structure. The photoinduced anodic current was observed when the composite film was immersed in an electrolyte solution containing triethanolamine as an electron donor. An action spectrum, which was quite similar to the absorption spectrum of CdS dispersion, indicates that the CdS nanoparticle keeps its size without mutual aggregation, and semiconducting properties even after being immobilized on the substrate.

    DOI CiNii

    Scopus

    197
    Citation
    (Scopus)

  • Layer-by-layer self-assembly of composite films of CdS nanoparticle and alkanedithiol on gold: an X-ray photoelectron spectroscopic characterization

    Takuya Nakanishi, Bunsho Ohtani, Katsuaki Shimazu, Kohei Uosaki

    Chemical Physics Letters   278 ( 4-6 ) 233 - 237  1997.10  [Refereed]  [International journal]

    Authorship：Lead author

    DOI CiNii

    Scopus

    60
    Citation
    (Scopus)

  • Construction of Semiconductor Nanoparticle Layers on Gold by Self-Assembly Technique

    Takuya Nakanishi, Bunsho Ohtani, Kohei Uosaki

    Japanese Journal of Applied Physics   36 ( 6B ) 4053 - 4056  1997.06  [Refereed]  [International journal]

    Authorship：Lead author

    　View Summary

    Cadmium sulfide (CdS) nanoparticles were prepared using the Aerosol-OT (AOT)/heptane inverse-micelle method. The particle size was controlled by changing the [H2O]/[AOT] ratio in the preparation process to be ca. 3 nm, which was estimated from their absorption maximum (ca. 385 nm) and absorption edge (ca. 450 nm) in heptane solutions. Self-assembled monolayers (SAMs) of α,ω-dithiols were prepared on (111)-oriented gold substrates. They were highly stable in aqueous solutions and showed a blocking effect toward electron exchange between the gold substrate and the electroactive species in the solution. Mono- and multi-layers of CdS nanoparticles were prepared by immersing the SAM-covered gold substrates in a heptane solution containing CdS particles. Infrared reflection-absorption spectra revealed that CdS particles on SAMs were surrounded by AOT and that a sequential immmersion procedure led to the alternately layered structure of CdS particles and dithiol molecules.

    DOI

    Scopus

    28
    Citation
    (Scopus)

  • Impedance of Electrode-Oxide Melts Containing Iron Oxide

    Toshio Yokokawa, Takuya Nakanishi

    The Electrochemical Society Proceeding Volumes   PV 94-13   350 - 356  1994  [Refereed]  [International journal]

    DOI

▼display all

Books and Other Publications

  • Electrochemistry at the Nanoscale (Editors: Patrik Schmuki, Sannakaisa Virtanen)

    Tetsuya Osaka, Takuya Nakanishi( Part： Contributor, "5.1 Oxide Nanoparticles" in "5 Nanoparticles" of "Electroless Fabrication of Nanostructures")

    Springer  2009.01 ISBN: 9780387735818

    DOI

  • 第５版 実験化学講座（日本化学会 編）２５巻『触媒化学，電気化学』

    中西卓也, 逢坂哲彌( Part： Contributor, 第６章３節３項「分子機能電極」)

    丸善  2006.01 ISBN: 9784621073247

  • 新訂版 表面科学の基礎と応用（日本表面科学会 編）

    大谷文章, 中西卓也( Part： Contributor, 第３編（応用編）第７章（触媒材料の設計・作製および評価）第１節（設計表面）３項「二次元不斉表面」)

    エヌティーエス  2004.06 ISBN: 4860430514

Presentations

  • Modification of a Solid Surface using Self-Assembled Monolayers for Biosensors and Chiral Sensors

     [Invited]

    International Conference on Materials Science and Engineering 2021 

    Presentation date： 2021.10

  • Nanoscale Design and Preparation of Solid-Liquid Interfaces for Biosensors and Chiral Sensors

     [Invited]

    3rd DGIST-WASEDA Workshop on Electrochemistry 

    Presentation date： 2015.12

  • Synthesis of Magnetite Nanoparticles using Organic Amines and Evaluation for Biomedical Applications

     [Invited]

    The Catholic University of Korea & Waseda University 2nd Joint Symposium 

    Presentation date： 2015.11

  • 電界効果トランジスタを利用したバイオセンサにおける固液ナノ界面

     [Invited]

    グリーンナノテクノロジー電極研究会「固液界面における物理化学と機能性界面物質相構築」ワークショップ 

    Presentation date： 2015.10

  • Design and Preparation of Nano-interfaces and Nano-materials for Biosensing and Biomedical Applications

     [Invited]

    International Symposium on Integration of Chemistry and Bioscience 

    Presentation date： 2014.01

  • 高性能センサが導く健やかな暮らしと社会

     [Invited]

    タスクフォース「未来社会創成の会」第一回フォーラム 

    Presentation date： 2013.11

  • Development of Nano-interfaces and Nano-materials for Biosensing and Biomedical Applications

     [Invited]

    DGIST-WASEDA Workshop on Electrochemistry 

    Presentation date： 2013.08

  • Chiral Specificity in Chiral Molecular Monolayer and Its Application to Chiral Sensing for Small Molecules

    12th Conference for BioSignal and Medicine (CBSM2013) 

    Presentation date： 2013.07

  • Synthesis of Magnetite Nanoparticles with Organic Amines and Evaluation of Their Properties for Biomedical Applications

     [Invited]

    International Conference of the Asian Union of Magnetic Societies (ICAUMS 2012) 

    Presentation date： 2012.10

  • Modification of Solid Surface with Self-Assembled Monolayer for Chiral Sensing

     [Invited]

    Pacific Rim Meeting on Electrochemical and Solid-State Science (PRiME 2012) 

    Presentation date： 2012.10

  • 有機アミンを用いたマグネタイトナノ粒子の合成とそのバイオ・医療応用に向けた評価

     [Invited]

    日本磁気学会ナノバイオ磁気工学専門研究会・電気化学会ナノマイクロファブリケーション研究会・表面技術協会表協エレクトロニクス部会合同研究会 

    Presentation date： 2012.06

  • Effect of Surface Modification of Indium Tin Oxide Electrode on Its Potential Response to Tryptophan

    The 62nd Annual Meeting of the International Society of Electrochemistry 

    Presentation date： 2011.09

  • Modification of Electrode Surface with Self-Assembled Monolayer for Analyte Recognition

     [Invited]

    2011 Korea-Waseda-Jilin Alliance Annual Symposium 

    Presentation date： 2011.06

  • Chiral Discrimination using a Self-Assembled Monolayer and Its Detection

     [Invited]

    The 2nd Symposium on Chiral Science & Technology: Mesochemistry & Chemical Wisdom 

    Presentation date： 2011.03

  • 粒径を制御したマグネタイトナノ粒子の合成とそのバイオ・医療応用に向けた検討

     [Invited]

    電子通信情報学会磁気記録・情報ストレージ研究会 

    Presentation date： 2010.11

  • 有機アミンを塩基に用いたマグネタイトナノ粒子の合成とそのバイオ分野への応用

     [Invited]

    2010年電気化学秋季大会 

    Presentation date： 2010.09

  • Chiral Sensing Based on the Formation of Diastereomeric Copper Complex on a Self-Assembled Monolayer of Homocysteine on Gold

    The 7th Asian Conference on Electrochemistry (ACEC 2010) 

    Presentation date： 2010.05

  • Detection of Biotin-Streptavidin Reaction by Optical Waveguide Spectroscopy with Gold and Silver Nanoparticles

    The 3rd Asian Conference on Colloid and Interface Science (ACCIS 2009) 

    Presentation date： 2009.10

  • Chiral Discrimination using a Self-Assembled Monolayer of Chiral Molecules

     [Invited]

    The Symposium on Chiral Science & Technology: Mesochemistry & Chemical Wisdom 

    Presentation date： 2009.09

  • New Trial on Nano Bio-Technology

     [Invited]

    7th International Symposium on Electrochemical Micro & Nanosystem Technologies (EMNT 2008) 

    Presentation date： 2008.09

  • Construction of New Biochips using Self-Assembled Monolayer

     [Invited]

    2008 Korean-Israeli Joint International Workshop on Cells-on-Chips 

    Presentation date： 2008.09

  • Biosensing by Optical Waveguide Spectroscopy with Gold Nanoparticles

    ASMeW International Symposium 

    Presentation date： 2008.08

  • Chiral Recognition using Nanoscale Chiral Spaces in a Self-Assembled Monolayer on Gold

    ASMeW International Symposium 

    Presentation date： 2008.08

  • Enantioselectivity of Redox Reaction of Catechins at the Gold Electrode Modified with a Self-Assembled Monolayer of Homocysteine

    International Conference on Electrified Interfaces 2007 (ICEC 2007) 

    Presentation date： 2007.06

  • ナノ物質相による固体表面修飾とセンシングへの応用

     [Invited]

    表面技術協会表協エレクトロニクス部会・電気化学会情報機能材料研究会合同研究会 

    Presentation date： 2006.12

  • Immobilization of Gold Nanoparticles on Optical Waveguides with Organosilane Monolayer

    Asian Conference on Nanoscience and Nanotechnology (AsiaNANO 2006) 

    Presentation date： 2006.11

  • Enantioselective Redox Reactions of Electrochemically-Active Chiral Molecules at the Gold Electrode Modified with Homocysteine

    Chirality 2006 - 18th International Symposium on Chirality (ISCD-18) 

    Presentation date： 2006.09

  • 有機単分子膜修飾界面でのキラル識別

     [Invited]

    第59回コロイドおよび界面化学討論会 

    Presentation date： 2006.09

  • 自己組織化単分子膜によるキラル識別

     [Invited]

    北海道大学創成科学研究機構－早稲田大学先端科学・健康医療融合研究機構交流会 

    Presentation date： 2006.09

  • Chiral Discrimination using Self-Assembled Monolayers

     [Invited]

    Nanotechnology Joint Symposium between Waseda University and Shanghai Jiao Tong University 

    Presentation date： 2006.02

  • Synthesis of Iron and Iron-Alloy Nanoparticles in a Two-Phase Liquid-Liquid System

    PACIFICHEM 2005 (The International Chemical Congress of Pacific Basin Societies) 

    Presentation date： 2005.12

  • 単分子膜修飾表面におけるキラル識別

     [Invited]

    講演会「固液界面における物理化学と機能性界面物質相構築 －最前線と未来展望－」 

    Presentation date： 2005.11

  • Enantioselective Redox Behavior of DOPA on Gold Electrode Modified with Homocysteine

    The 56th Annual Meeting of the International Society of Electrochemistry 

    Presentation date： 2005.09

  • Crystallization of Leucine on a Self-Assembled Monolayer with Covalently Attached Enantiomeric Leucine Molecules

    The 11th International Conference on Organized Molecular Films (LB11) 

    Presentation date： 2005.06

  • Synthesis of Iron-Containing Oxide Nanoparticles in Reverse Micelles

    The 5th Asian Conference on Electrochemistry (ACEC 2005) 

    Presentation date： 2005.05

  • 液液二相系を用いた鉄ナノ粒子の調製

    電気化学会第72回大会 

    Presentation date： 2005.04

  • Application of a Two-phase Liquid-Liquid System to the Synthesis of Iron-Containing Nanoparticles

    206th Meeting of The Electrochemical Society 

    Presentation date： 2004.10

  • Enantioselective Crystallization on Self-Assembled Monolayers and Its Application to Chiral Sensing

    10th International Meeting on Chemical Sensors (10-IMCS) 

    Presentation date： 2004.07

  • 自己組織化単分子膜修飾表面によるキラル認識

     [Invited]

    電気化学会関東支部第50回サイエンスレクチャー 

    Presentation date： 2004.07

  • 自己組織化単分子膜修飾金基板上でのロイシン結晶化とそのキラル選択性

    日本化学会第84春季年会 

    Presentation date： 2004.03

  • 自己組織化単分子膜を用いたキラル認識

     [Invited]

    電気化学会第７回楽市フォーラムの会 

    Presentation date： 2004.02

  • Application of solid surfaces modified with self-assembled monolayers to the study of chiral discrimination

    21COE International Symposium on 'Practical Nano-Chemistry' 

    Presentation date： 2003.12

  • Chiral Discrimination between Thalidomide Enantiomers by Using a Solid Surface with Two-Dimensional Chirality

    Chirality 2003 - The 15th International Symposium on Chirality (ISCD-15) 

    Presentation date： 2003.10

  • 軸不斉化合物自己組織化単分子膜のキラル認識場としての評価：サリドマイドのキラル選択的吸着

    日本化学会第82秋季年会 

    Presentation date： 2002.09

  • 自己組織化単分子層をシード層へ適用した無電解NiReP拡散防止層の作製と評価

    電気化学会第69回大会 

    Presentation date： 2002.04

  • 軸不斉化合物自己組織化単分子膜のキラル認識場としての評価：フェニルアラニンのキラル選択的吸着

    日本化学会第81春季年会 

    Presentation date： 2002.03

  • 軸不斉化合物自己組織化単分子膜修飾QCMによる光学活性アミノ酸吸着挙動の評価

    電気化学会第68回大会 

    Presentation date： 2001.04

  • Pulsed-Current Electrodeposition of Soft Magnetic CoNiFe Thin Films

    198th Meeting of The Electrochemical Society 

    Presentation date： 2000.10

  • Structural Characterization of Nanocrystalline CoNiFe Thin Films Prepared by Pulsed Electrodeposition

    International Symposium on Electrochemistry of Ordered Interface 2000 

    Presentation date： 2000.08

  • パルス電析法によるCoNiFe軟磁性薄膜の作製

    電気化学会第67回大会 

    Presentation date： 2000.04

  • Preparation and Characterization of High Bs Soft Magnetic Films by Plating Method

     [Invited]

    The 50th Annual Meeting of International Society of Electrochemistry 

    Presentation date： 1999.09

  • Fabrication, Structure, and Photoelectrochemical Properties of Semiconductor-Nanoparticle Monolayers Attached on Gold using Self-Assembled Monolayers of Dithiols

    2nd International Symposium on Electrochemical Microsystem Technologies 

    Presentation date： 1998.09

  • 半導体超微粒子を用いた光機能性表面の創製

     [Invited]

    電気化学会北海道支部第16回ライラックセミナー・第5回若手研究者交流会 

    Presentation date： 1998.06

  • Fabrication and Characterization of Semiconductor-Particle Monolayers Attached on a Self-Assembled Monolayer of Alkanedithiol

    215th American Chemical Society National Meeting 

    Presentation date： 1998.03

  • ZnS超微粒子および機能分子と複合化したCdS超微粒子層膜の調製と特性評価

    日本化学会北海道支部1998年冬季研究発表会 

    Presentation date： 1998.02

  • CdS超微粒子／アルカンジチオール交互累積層の構造と光機能

    日本化学会第73秋季年会 

    Presentation date： 1997.09

  • CdS超微粒子／アルカンジチオール交互累積層膜の調製と特性

    電気化学会第64回大会 

    Presentation date： 1997.03

  • 自己組織化法によるCdS超微粒子／ジチオール複合層の構築

    日本化学会北海道支部1997年冬季研究発表会 

    Presentation date： 1997.02

  • Construction of Semiconductor Nanoparticle Layers on Gold by Self-Assembly Technique

    QDS '96 (1996 International Symposium on Formation, Physics and Device Application of Quantum Dot Structures) 

    Presentation date： 1996.11

  • 溶融ほう酸塩のインピーダンス解析 －電気伝導度および酸素電極反応－

    第26回溶融塩化学討論会 

    Presentation date： 1994.11

  • 酸化物融体と金属系のインピーダンス（第4報）：酸化鉄の寄与

    日本金属学会1994年春期(第114回)大会 

    Presentation date： 1994.03

  • 酸化物融体-電極界面のインピーダンス測定

    平成5年度冬季日本金属学会・日本鉄鋼協会両北海道支部講演大会 

    Presentation date： 1994.01

  • スラグの酸化還元とインピーダンス（III）

    日本金属学会1993年秋期(第113回)大会 

    Presentation date： 1993.10

  • Na2O-B2O3系融体中におけるMoイオンの酸化還元挙動

    第19回電気化学協会北海道支部研究発表会 

    Presentation date： 1993.01

▼display all

Research Projects

  • メソポーラス半導体膜の特徴的なナノ細孔を活かした光学特性の制御と受光素子の開発

    独立行政法人日本学術振興会  科学研究費助成事業 (学術研究助成基金助成金)

    Project Year :

    2024.04
    -
    2027.03
     

    中川鉄馬, 中西卓也

  • Establishment of Electrochemical Device Engineering

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research

    Project Year :

    2008
    -
    2012
     

    OSAKA Tetsuya, MOMMA Toshiyuki, SHOJI Shuichi, SUGIYAMA Atsushi, NAKANISHI Takuya, HOMMA Takayuki, MATSUKATA Masahiko, MIZUNO Jun, SEKIGUCHI Tetsushi, YOSHINO Masahiro, TOMINAKA Satoshi

    　View Summary

    Based on the researches for development of functional materials with the control of solid-liquid interface and for development of devices with the practical use of nano- and meso-structures and phenomena at the interface, the establishment of Electrochemical Device Engineering was promoted. To establish Electrochemical Device Engineering on the basis of Electrochemical Nanotechnology, the practical devices utilizing the outcome of research and the dimensions for appearance of function and design of solid-liquid interface were set as the warp and weft of this academic discipline.

  • 自己組織化単分子膜によるキラル識別とその効果的検出法の開発

    東京応化科学技術振興財団  第24回研究費の助成

    Project Year :

    2010.04
    -
    2011.03
     

  • 超高密度磁気記録用軟磁性薄膜の電気化学的作製とナノ構造制御による高機能発現

    日本学術振興会  科学研究費助成事業

    Project Year :

    2002
    -
    2004
     

    中西 卓也

Misc

  • Oxidative Desorption Behavior of Sulfur Species from Pt and Pt Based Alloy Single Crystal Surfaces

    Tetsuro Morooka, Makoto Aoki, Takuya Nakanishi, Atsushi Ishikawa, Takuya Masuda

    ECS Meeting Abstracts   MA2024-02 ( 58 ) 3919 - 3919  2024

    DOI

  • Electrochemical investigation of protein-protein interactions involving intrinsically disordered protein Praja1 on gold substrates

    Mori Wataru, Nakanishi Takuya, Onodera Wataru, Kojima Terutoshi, Asahi Toru

    Abstract book of Annual Meeting of the Japan Society of Vacuum and Surface Science   2024   3P102  2024

    DOI

  • Adsorption/Desorption Behaviors of Sulfur Species at Pt Single Crystal Surfaces

    Tetsuro Morooka, Ganesan Elumalai, Ruttala Devivaraprasad, Tamao Shishido, Takuya Nakanishi, Toshihiro Kondo, Takuya Masuda

    ECS Meeting Abstracts   MA2023-01 ( 38 ) 2243 - 2243  2023

    DOI

  • Oxidative Desorption of Adsorbed Sulfur on Platinum Surfaces Modified with Cerium Species

    Tetsuro Morooka, Takuya Nakanishi, Takuya Masuda

    ECS Meeting Abstracts   MA2023-01 ( 38 ) 2241 - 2241  2023

    DOI

  • High sensitivity acetone detection with In-doped WO3 thin film on microstructure substrate

    岩瀬大輝, ZHU Zicheng, 中西卓也, 朝日透

    応用物理学会春季学術講演会講演予稿集(CD-ROM)   70th  2023

    J-GLOBAL

  • Oxidative Desorption Behavior of Sulfur Species Adsorbed on Pt Single Crystal Electrode Surface

    諸岡哲朗, DEVIVARAPRASAD Ruttala, GANESAN Elumalai, 宍戸玉緒, 中西卓也, 近藤敏啓, 増田卓也

    電気化学秋季大会講演要旨集(Web)   2022  2022

    J-GLOBAL

  • Fabrication of Aptamer-Immobilized Multi-Target Field-Effect Transistor Biosensor for Sensing Mental Stress

    Shigeki Kuroiwa, Ryota Takibuchi, Akane Matsuzaka, Sho Hideshima, Naoto Kaneko, Hirotaka Minagawa, Katsunori Horii, Iwao Waga, Takuya Nakanishi, Keishi Ohashi, Toshiyuki Momma, Tetsuya Osaka

    ECS Meeting Abstracts   MA2017-02 ( 49 ) 2115 - 2115  2017

    DOI

  • Label-Free and Highly Sensitive Detection of Buckwheat 16kD Allergenic Protein with Field Effect Transistor (FET) Sensor and Immunochromatography Strip

    Yoshitaka Harada, Mika Tsuna, Sho Hideshima, Mai Saito, Shigeki Kuroiwa, Takuya Nakanishi, Tetsuya Osaka

    ECS Meeting Abstracts   MA2017-02 ( 56 ) 2353 - 2353  2017

    DOI

  • Development of Semiconductor-Based Biosensor for Detection of Buckwheat Allergenic Protein in Food Products

    Sho Hideshima, Mai Saito, Yoshitaka Harada, Mika Tsuna, Shigeki Kuroiwa, Takuya Nakanishi, Tetsuya Osaka

    ECS Meeting Abstracts   MA2017-02 ( 56 ) 2352 - 2352  2017

    DOI

  • α-アミラーゼアプタマー固定化電界効果トランジスタ型バイオセンサーの作製とα-アミラーゼの検出

    松坂朱峰, 秀島翔, 金子直人, 堀井克紀, 和賀巌, 黒岩繁樹, 中西卓也, 大橋啓之, 門間聰之, 逢坂哲彌

    日本化学会春季年会講演予稿集(CD-ROM)   97th  2017

    J-GLOBAL

  • GRAPHENE OXIDE COATING ON GATE INSULATOR OF FIELD EFFECT TRANSISTOR BIOSENSOR FOR IMPROVEMENT OF ITS LONG-TERM STABILITY DURING STORAGE IN SOLUTION

    竹内亮, 秀島翔, 黒岩繁樹, 中西卓也, 門間聰之, 逢坂哲彌

    Chemical Sensors   33 ( Supplement B )  2017

    J-GLOBAL

  • MgFe2O4ナノ粒子の合成と交流磁場下での発熱によるヒト乳がん細胞の死滅誘導

    金津真帆, 松田翔風, 中西卓也, 柏俣佑果, 門間聰之, 逢坂哲彌

    日本磁気学会学術講演概要集   40th  2016

    J-GLOBAL

  • 電界効果トランジスタを用いたタンパク質検出に界面活性剤処理が及ぼす影響

    齊藤真衣, 藤田圭祐, 秀島翔, 原田義孝, 綱美香, 黒岩繁樹, 中西卓也, 逢坂哲彌

    電気化学会大会講演要旨集(CD-ROM)   83rd  2016

    J-GLOBAL

  • 磁気ハイパーサーミア応用へ向けた銅亜鉛フェライトナノ粒子の合成と特性評価

    宮崎航大, 松田翔風, 中西卓也, 門間聰之, 逢坂哲彌

    粉体粉末冶金協会講演概要集   2016  2016

    J-GLOBAL

  • 電界効果トランジスタ(FET)センサを用いたソバ16kDアレルゲンタンパク質の非標識高感度検出

    原田義孝, 綱美香, 藤田圭祐, 秀島翔, 黒岩繁樹, 中西卓也, 逢坂哲彌

    日本農芸化学会大会講演要旨集(Web)   2016  2016

    J-GLOBAL

  • EFFECT OF SURFACTANT TREATMENT ON PROTEIN DETECTION USING FIELD EFFECT TRANSISTOR

    齊藤真衣, 藤田圭祐, 秀島翔, 原田義孝, 綱美香, 黒岩繁樹, 中西卓也, 逢坂哲彌

    Chemical Sensors   32 ( Supplement A )  2016

    J-GLOBAL

  • ELECTROCHEMICAL MICRO & NANOSYSTEM TECHNOLOGIES Foreword

    Tetsuya Osaka, Takuya Nakanishi

    ELECTROCHIMICA ACTA   183   1 - 2  2015.11

    Other  

    DOI

  • Amplification Strategy of FET Biosensor Signal for Sensitive Detection of Prion Proteins

    Shofarul Wustoni, Sho Hideshima, Shigeki Kuroiwa, Takuya Nakanishi, Tetsuya Osaka

    ECS Meeting Abstracts   MA2015-02 ( 45 ) 1804 - 1804  2015

    DOI

  • PtCu電析とCu脱合金化による色素増感太陽電池用高表面積Pt電極の作製

    田中俊, 黒岩繁樹, 中西卓也, 逢坂哲彌

    電気化学会大会講演要旨集(CD-ROM)   82nd  2015

    J-GLOBAL

  • DETECTION OF HEMAGGLUTININ DISSOCIATED FROM INFLUENZA VIRUS USING GLYCAN-IMMOBILIZED FIELD EFFECT TRANSISTOR

    南部谷俊介, 前川達洋, 秀島翔, 比能洋, 西村紳一郎, 迫田義博, 黒岩繁樹, 中西卓也, 逢坂哲彌

    Chemical Sensors   31 ( Supplement A )  2015

    J-GLOBAL

  • 糖鎖固定化電界効果トランジスタによるインフルエンザウイルスから分離したヘマグルチニンの検出

    南部谷俊介, 前川達洋, 秀島翔, 比能洋, 西村紳一郎, 迫田義博, 黒岩繁樹, 中西卓也, 逢坂哲彌

    電気化学会大会講演要旨集(CD-ROM)   82nd  2015

    J-GLOBAL

  • 上皮型及び混合型中皮腫細胞にマグネタイトナノ粒子の取り込みと交流磁場印加が及ぼす影響

    中嶋恵里, 松田翔風, 中西卓也, 張弘, 田中あかね, 松田浩珍, 逢坂哲彌

    日本生化学会大会(Web)   88th  2015

    J-GLOBAL

  • 細胞内および細胞外に存在するマグネタイト粒子の発熱がヒト乳がん細胞に与える死滅効果

    金子恭彩子, 松田翔風, 中西卓也, 張弘, 逢坂哲彌

    日本生化学会大会(Web)   88th  2015

    J-GLOBAL

  • Toward Industrialization on Semiconductor-Based Biosensors in Health and Medical Fields

    Sho Hideshima, Shigeki Kuroiwa, Takuya Nakanishi, Masahiro Hashimoto, Yasuro Mori, Tetsuya Osaka

    ECS Meeting Abstracts   MA2014-02 ( 16 ) 884 - 884  2014

    DOI

  • Effect of the Receptor Size on the Sensitivity of Field Effect Transistor Biosensor for Label-Free Detection of Cancer Biomarker

    Shanshan Cheng, Kaori Hotani, Sho Hideshima, Shigeki Kuroiwa, Takuya Nakanishi, Yasuro Mori, Tetsuya Osaka

    ECS Meeting Abstracts   MA2014-01 ( 5 ) 431 - 431  2014

    DOI

  • マグネタイトナノ粒子の発熱がヒト乳がん細胞MCF-7の生存率に及ぼす影響のin vitro評価

    金子恭彩子, 松田翔風, 中西卓也, ZHANG Hong, 逢坂哲彌

    日本分子生物学会年会プログラム・要旨集(Web)   37th  2014

    J-GLOBAL

  • マグネタイトナノ粒子を取り込んだ中皮腫細胞への交流磁場照射が細胞死に与える影響

    日辻愛理, 松田翔風, 中西卓也, ZHANG Hong, 逢坂哲彌

    日本分子生物学会年会プログラム・要旨集(Web)   37th  2014

    J-GLOBAL

  • Effect of Amyloid Conformation On the Response of Field Effect Transistor Biosensor to Sup35NM Protein

    Sho Hideshima, Shofarul Wustoni, Shigeki Kuroiwa, Takuya Nakanishi, Ayumi Koike-Takeshita, Tetsuya Osaka

    ECS Meeting Abstracts   MA2013-02 ( 47 ) 2672 - 2672  2013

    DOI

  • 電折・脱合金化法による色素増感太陽電池用高表面積白金電極の作製

    喜屋武厚, 黒岩繁樹, 中西卓也, 逢坂哲彌

    電気化学秋季大会講演要旨集   2013  2013

    J-GLOBAL

  • マグネタイトナノ粒子の取り込みがマウスマクロファージの機能に及ぼす影響

    筒井菜々子, 張弘, 中西卓也, 田中あかね, 松田浩珍, 逢坂哲彌

    日本分子生物学会年会プログラム・要旨集(Web)   36th  2013

    J-GLOBAL

  • DETECTION OF AMYLOID β WITH DIFFERENT AGGREGATE MORPHOLOGY BY USING FIELD EFFECT TRANSISTORS

    小林万純, 秀島翔, 黒岩繁樹, 中西卓也, 澤村直哉, 朝日透, 逢坂哲彌

    Chemical Sensors   29 ( Supplement A )  2013

    J-GLOBAL

  • 中皮腫細胞へのマグネタイトナノ粒子の取り込みとその交流磁場下での発熱による細胞死の評価

    日辻愛理, 松田翔風, 中西卓也, ZHANG H., 田中あかね, 松田浩珍, 逢坂哲彌

    電気化学会大会講演要旨集   80th  2013

    J-GLOBAL

  • DETECTION OF MATRIX METALLOPROTEINASE-2 BY FIELD EFFECT TRANSISTOR UTILIZING DEGRADATION OF FIBRONECTIN

    山本大輔, 秀島翔, 黒岩繁樹, 中西卓也, 逢坂哲彌

    Chemical Sensors   29 ( Supplement A )  2013

    J-GLOBAL

  • フィブロネクチンの分解反応を利用したマトリックスメタロプロテアーゼ-2のFETによる検出

    山本大輔, 秀島翔, 黒岩繁樹, 中西卓也, 逢坂哲彌

    電気化学会大会講演要旨集   80th  2013

    J-GLOBAL

  • 電界効果トランジスタを用いた凝集形態の異なるアミロイドβの検出

    小林万純, 秀島翔, 黒岩繁樹, 中西卓也, 澤村直哉, 朝日透, 逢坂哲彌

    電気化学会大会講演要旨集   80th  2013

    J-GLOBAL

  • 腫瘍マーカーの電気的検出におけるプローブ分子小型化による高感度化

    宝谷佳織, 程サンサン, 秀島翔, 黒岩繁樹, 中西卓也, 逢坂哲彌

    日本分子生物学会年会プログラム・要旨集(Web)   36th  2013

    J-GLOBAL

  • マグネタイトナノ粒子の中皮腫細胞への取り込みとその発熱による細胞死の評価

    日辻愛理, 松田翔風, 中西卓也, 張弘, 田中あかね, 松田浩珍, 逢坂哲彌

    日本分子生物学会年会プログラム・要旨集(Web)   36th  2013

    J-GLOBAL

  • Field Effect Transistor Based Micro Sensors ―pH Sensors and Biosensors―

    Tetsuya Osaka, Shigeki Kuroiwa, Sho Hideshima, Takuya Nakanishi

    Chemical Sensors   28 ( 1 ) 8 - 15  2012.03  [Refereed]

    Article, review, commentary, editorial, etc. (scientific journal)  

    CiNii J-GLOBAL

  • Development of Specific Delivery of Magnetic Nanoparticles in Cancer Tissue for Hyperthermia and Their Establishment of System for Safety Assessment

    Hong Zhang, Takuya Nakanishi, Tetsuya Osaka

    ECS Meeting Abstracts   MA2012-02 ( 48 ) 3431 - 3431  2012

    DOI

  • (Invited) Modification of Solid Surface with Self-Assembled Monolayer for Chiral Sensing

    Takuya Nakanishi, Tetsuya Osaka

    ECS Meeting Abstracts   MA2012-02 ( 44 ) 3254 - 3254  2012

    DOI

  • マウスマクロファージによるマグネタイトナノ粒子取り込み挙動の評価

    筒井菜々子, ZHANG Hong, 中西卓也, 田中あかね, 松田浩珍, 逢坂哲彌

    日本分子生物学会年会プログラム・要旨集(Web)   35th  2012

    J-GLOBAL

  • 中皮腫細胞へのマグネタイトナノ粒子の取り込みと細胞毒性作用

    松田翔風, ZHANG Hong, 中西卓也, 田中あかね, 松田浩珍, 逢坂哲彌

    日本分子生物学会年会プログラム・要旨集(Web)   35th  2012

    J-GLOBAL

  • ポリエチレンイミン修飾マグネタイトナノ粒子のヒト由来乳がん細胞及び正常ヒト臍帯血細胞に対する取り込みの評価

    清古康弘, 馬場大輔, ZHANG H., 中西卓也, 逢坂哲彌

    電気化学会大会講演要旨集   79th  2012

    J-GLOBAL

  • マグネタイトナノ粒子の中皮腫細胞への取り込み及び殺傷効果の評価

    松田翔風, 馬場大輔, ZHANG H., 中西卓也, 田中あかね, 松田浩珍, 逢坂哲彌

    電気化学会大会講演要旨集   79th  2012

    J-GLOBAL

  • DETECTION OF L-LYSINE USING FIELD EFFECT TRANSISTOR WITH LYSINE DECARBOXYLASE IMMOBILIZED ON THE GATE

    井上智之, 山本大輔, 中西卓也, 逢坂哲彌

    Chemical Sensors   78th(CD-ROM) ( Supplement A )  2011

    J-GLOBAL

  • スペルミンを用いて合成した粒子径の異なるマグネタイトナノ粒子の磁性および発熱特性の評価

    馬場大輔, 清古康弘, ZHANG H., 新垣篤史, 中西卓也, 松永是, 逢坂哲彌

    電気化学会大会講演要旨集   78th(CD-ROM)  2011

    J-GLOBAL

  • ポリエチレンイミン修飾マグネタイトナノ粒子の発熱によるがん細胞の死滅評価

    清古康弘, 馬場大輔, ZHANG H., 新垣篤史, 中西卓也, 松永是, 逢坂哲彌

    電気化学会大会講演要旨集   78th(CD-ROM)  2011

    J-GLOBAL

  • DETECTION OF L-LYSINE USING FIELD EFFECT TRANSISTOR WITH LYSINE DECARBOXYLASE IMMOBILIZED ON THE GATE

    井上智之, 山本大輔, 中西卓也, 逢坂哲彌

    Chemical Sensors   27 ( Supplement A )  2011

    J-GLOBAL

  • DETECTION OF L-LYSINE USING FIELD EFFECT TRANSISTOR WITH LYSINE OXIDASE IMMOBILIZED ON THE GATE

    井上智之, 佐藤絵美子, 中西卓也, 逢坂哲彌

    Chemical Sensors   27 ( Supplement B )  2011

    J-GLOBAL

  • Size‐tuned Synthesis of Magnetite Nanoparticles and Their Biomedical Application

    Takuya Nakanishi, Hong Zhang, Tetsuya Osaka

    IEICE Technical Report (Institute of Electronics, Information and Communication Engineers)   110 ( 310(MR2010 34-41) ) 13 - 15  2010.11  [Invited]

    J-GLOBAL

  • Safety of magnetite nanoparticles into mouse embryonic stem cells

    春藤千草, ZHANG Hong, 中西卓也, 逢坂哲彌

    生化学    2010

    J-GLOBAL

  • ホモシステイン単分子膜修飾FETを用いた種々のアミノ酸のキラル識別

    山本大輔, 中西卓也, 逢坂哲彌

    電気化学会大会講演要旨集   77th  2010

    J-GLOBAL

  • 有機アミンを塩基に用いたマグネタイトナノ粒子の合成とそのバイオ分野への応用

    中西卓也, ZHANG Hong, 逢坂哲彌

    電気化学秋季大会講演要旨集   2010  2010

    J-GLOBAL

  • 発熱効率向上を目的としたマグネタイトナノ粒子の粒径及び分散性の制御

    馬場大輔, 新垣篤史, 中西卓也, 松永是, 逢坂哲彌

    日本磁気学会学術講演概要集   34th  2010

    J-GLOBAL

  • Detection of Human Chorionic Gonadotropin using Stable Field Effect Transistor with Antibody-Modified Gate

    Sho Hideshima, Takuya Nakanishi, Tetsuya Osaka

    ECS Meeting Abstracts   MA2009-02 ( 14 ) 1628 - 1628  2009

    DOI

  • Organic Molecular Sensor with Plasmon Antenna

    Masahiro Yanagisawa, Naonobu Shimamoto, Takuya Nakanishi, Mikiko Saito, Tetsuya Osaka

    ECS Meeting Abstracts   MA2008-02 ( 50 ) 3140 - 3140  2008

    DOI

  • 人工ホットスポットを用いたSAM膜のラマン検出

    柳沢雅広, 島本直伸, 中西卓也, 齋藤美紀子, 逢坂哲彌, 上野太郎, 船津高志

    応用物理学関係連合講演会講演予稿集   55th ( 3 )  2008

    J-GLOBAL

  • 同心円プラズモンアンテナ型分子センサーの設計と表面増強ラマン散乱による分子の検出

    柳沢雅広, 中西卓也, 梶浦真由紀, 島本直伸, 齋藤美紀子, 会田敏之, 加藤邦男, 逢坂哲彌

    表面科学学術講演会講演要旨集   28th  2008

    J-GLOBAL

  • 電気化学界面でのSAMを利用したキラル認識システム

    逢坂哲彌, 中西卓也, 松永真理子

    表面科学学術講演会講演要旨集   28th  2008

    J-GLOBAL

  • イオン液体を溶媒とするFePtナノ粒子の化学的合成

    蜂巣琢磨, 川北泉, 丸山理紗, 飯田広範, 杉山敦史, 中西卓也, 逢坂哲彌

    日本磁気学会学術講演概要集   32nd  2008

    J-GLOBAL

  • マグネタイトナノ粒子の粒径および表面修飾が溶液分散性に及ぼす影響

    高濱慎太郎, 飯田広範, 高柳浩介, 中西卓也, 逢坂哲彌

    電気化学会大会講演要旨集   75th  2008

    J-GLOBAL

  • アルブミン固定化ITO電極のTrp添加にともなう電位応答におけるキラル選択性

    上野翼, 松永真理子, 中西卓也, 逢坂哲彌

    電気化学会大会講演要旨集   75th  2008

    J-GLOBAL

  • Molecular modification of ITO electrode for chiral discrimination

    Ueno Tsubasa, Matsunaga Mariko, Nakanishi Takuya, Osaka Tetsuya

    Abstract of annual meeting of the Surface Science of Japan   28th ( 0 ) 29 - 29  2008

    DOI CiNii J-GLOBAL

  • 金ナノ粒子を用いた光導波路分光法による生体分子間反応の検出

    梶浦真由紀, 中西卓也, 飯田広範, 逢坂哲彌

    応用物理学会学術講演会講演予稿集   69th ( 3 )  2008

    J-GLOBAL

  • マグネタイトナノ粒子の正常細胞とがん細胞への取り込み評価

    高浜慎太郎, ZHANG H., 中西卓也, 逢坂哲彌

    日本磁気学会学術講演概要集   32nd  2008

    J-GLOBAL

  • Effect of Growth Temperature of FePt Nanoparticles on the L10-Ordering in Post-Synthesis Annealing

    Takuma Hachisu, Atsushi Sugiyama, Hironori Iida, Takuya Nakanishi, Toru Asahi, Tetsuya Osaka

    ECS Meeting Abstracts   MA2007-02 ( 1 ) 23 - 23  2007

    DOI

  • 加水分解反応による酸化鉄ナノ粒子の合成-粒径と磁気特性の制御-

    飯田広範, 高柳浩介, 中西卓也, 逢坂哲彌

    日本化学会講演予稿集   87th ( 1 )  2007

    J-GLOBAL

  • 新規磁気記録媒体用の立方状fcc-FePtナノ粒子の作製

    蜂巣琢磨, 杉山敦史, 飯田広範, 中西卓也, 朝日透, 逢坂哲彌

    日本応用磁気学会学術講演概要集   31st  2007

    J-GLOBAL

  • リポソーム封入マグネタイトナノ粒子の作製と磁気特性の評価

    高柳浩介, 飯田広範, 高浜慎太郎, 中西卓也, 逢坂哲彌

    電気化学秋季大会講演要旨集   2007  2007

    J-GLOBAL

  • 金ナノ粒子固定化光導波路上におけるビオチン-ストレプトアビジン反応の検出

    梶浦真由紀, 高田晴美, 飯田広範, 中西卓也, 逢坂哲彌

    電気化学会大会講演要旨集   74th  2007

    J-GLOBAL

  • Fabrication of High-B_s CoFe Film by Pulsed Electrodeposition

    LIN Bingrong, YOSHIDA Midori, NAKANISHI Takuya, SUGIYAMA Atsushi, OSAKA Tetsuya

    IEICE technical report. Magnetic recording   106 ( 335 ) 41 - 42  2006.11

    CiNii

  • 電析CoFe薄膜の磁気特性に及ぼすめっき下地層の影響

    LIN Bingrong, 平岩稔久, 中西卓也, 杉山敦史, 逢坂哲彌

    表面技術協会講演大会講演要旨集   113th  2006

    J-GLOBAL

  • Synthesis of iron oxide nanoparticles by hydrolysis with 1,6-hexanediamine

    高柳浩介, 飯田広範, 中西卓也, 逢坂哲彌

    日本化学会講演予稿集   86th ( 1 )  2006

    J-GLOBAL

  • 光導波路上への金ナノ粒子の固定化および表面プラズモン吸収特性の評価

    高田晴美, 梶浦真由紀, 飯田広範, 中西卓也, 逢坂哲彌

    電気化学秋季大会講演要旨集   2006  2006

    J-GLOBAL

  • Development of electrochemical chiral sensing method by using chiral ligand exchange on the Au electrode modified with L-Homocysteine

    松永真理子, 巽智香, 中西卓也, 朝日透, 逢坂哲彌

    日本化学会講演予稿集   86th ( 1 )  2006

    J-GLOBAL

  • Formation of nanoparticle composite by interparticle linkage between iron-oxide and gold nanoparticles

    飯田広範, 中西卓也, 逢坂哲彌

    日本化学会講演予稿集   86th ( 1 )  2006

    J-GLOBAL

  • ホモシステイン単分子膜修飾金電極におけるカテキンの酸化還元のキラル選択性

    長坂誠, 上野翼, 松永真理子, 中西卓也, 朝日透, 逢坂哲彌

    電気化学秋季大会講演要旨集   2006  2006

    J-GLOBAL

  • 逆ミセルを用いた鉄系複合酸化物ナノ粒子の調製

    高田晴美, 飯田広範, 中西卓也, 逢坂哲彌

    電気化学会大会講演要旨集   72nd  2005

    J-GLOBAL

  • システインおよびホモシステイン単分子膜修飾金電極におけるDOPAの酸化還元挙動の比較

    松永真理子, 中西卓也, 長坂誠, 朝日透, 逢坂哲彌

    電気化学会大会講演要旨集   72nd  2005

    J-GLOBAL

  • ホモシステイン単分子膜修飾金電極におけるDOPAのキラル選択的酸化還元-DOPA濃度およびpHの影響

    長坂誠, 松永真理子, 中西卓也, 朝日透, 逢坂哲彌

    電気化学秋季大会講演要旨集   2005  2005

    J-GLOBAL

  • 液液二相系を用いた鉄ナノ粒子の調製

    中西卓也, 飯田広範, 高田晴美, 逢坂哲彌

    電気化学会大会講演要旨集   72nd  2005

    J-GLOBAL

  • 逆ミセル系での還元-酸化反応による酸化鉄ナノ粒子形成に及ぼす因子:還元剤種と雰囲気の効果

    飯田広範, 高田晴美, 中西卓也, 逢坂哲彌

    電気化学会大会講演要旨集   72nd  2005

    J-GLOBAL

  • 無電解銅めっきにおける添加剤の微細配線溝フィリングへの効果とその電気化学的解析

    長谷川円, 滝佐和子, 中西卓也, 笹野順司, 沖中裕, 松田五明, Shacham-Diamand Yosi, 逢坂哲彌

    電気化学会大会講演要旨集   72nd  2005

    J-GLOBAL

  • ULSI内部配線形成を目的とした無電解銅めっきにおける添加剤の効果

    滝佐和子, 長谷川円, 中西卓也, 沖中裕, 逢坂哲彌

    表面技術協会講演大会講演要旨集   111th  2005

    J-GLOBAL

  • ホモシステイン単分子膜修飾金電極におけるDOPAの酸化還元のキラル選択性

    長坂誠, 松永真理子, 中西卓也, 朝日透, 逢坂哲彌

    電気化学会大会講演要旨集   72nd  2005

    J-GLOBAL

  • Decrease in H_c of high-B_s CoFe thin films by means of pulsed electrodeposition

    HIRAIWA T., SENUMA H., NAKANISHI T., SUGIYAMA A., OSAKA T.

    日本応用磁気学会学術講演概要集   28   5 - 5  2004.09

    CiNii J-GLOBAL

  • Characterization of γ-Fe2O3 nanoparticles modified with aminopropylsilyl groups

    飯田広範, 中西卓也, 逢坂哲彌

    日本化学会講演予稿集   84th ( 1 )  2004

    J-GLOBAL

  • Crystallization of leucine on a gold surface modified with a self-assembled monolayer and its enantioselectivity

    中西卓也, 伴野直樹, 松永真理子, 朝日透, 逢坂哲彌

    日本化学会講演予稿集   84th ( 1 )  2004

    J-GLOBAL

  • ULSI配線用ダマシン銅めっきにおけるJGBの添加効果

    根岸芳典, 長谷川円, 横島時彦, 中西卓也, 逢坂哲彌

    表面技術協会講演大会講演要旨集   109th  2004

    J-GLOBAL

  • ULSI配線用ダマシン銅めっきにおける添加剤が析出膜特性に及ぼす影響

    根岸芳典, 長谷川円, 中西卓也, 逢坂哲彌

    表面技術協会講演大会講演要旨集   110th  2004

    J-GLOBAL

  • Preparation of Iron-Oxide Nanoparticles in Reverse Micelles

    飯田広範, 中西卓也, 逢坂哲彌

    日本化学会講演予稿集   83rd ( 1 )  2003

    J-GLOBAL

  • γ-酸化鉄ナノ粒子の調製と磁気特性の評価

    飯田広範, 中西卓也, 逢坂哲彌

    電気化学秋季大会講演要旨集   2003  2003

    J-GLOBAL

  • Crystallographic Study on Chiral and Racemic Single Crystal of Leucine

    朝日透, 中西卓也, 伴野直樹, 松永真理子, 後藤隆弘, 逢坂哲彌

    日本化学会講演予稿集   83rd ( 1 )  2003

    J-GLOBAL

  • Characterization of crystalline phase of leucine formed on a self-assembled monolayer : the influence of solution conditions

    伴野直樹, 松永真理子, 中西卓也, 朝日透, 逢坂哲彌

    日本化学会講演予稿集   83rd ( 1 )  2003

    J-GLOBAL

  • Substrate dependence of the crystal growth of leucine on a self-assembled monolayer on gold

    松永真理子, 伴野直樹, 中西卓也, 朝日透, 逢坂哲彌

    日本化学会講演予稿集   83rd ( 1 )  2003

    J-GLOBAL

  • ULSI銅配線用バリア層形成における無電解NiBめっきプロセス

    野中佑一, 吉野正洋, 横島時彦, 中西卓也, 逢坂哲彌

    エレクトロニクス実装学術講演大会講演論文集   17th (Web)  2003

    J-GLOBAL

  • Characterization of a Self-Assembled Monolayer of Atropisomeric Compound as a Field for Chiral Discrimination: Enantioselective Adsorption of Thalidomide

    中西卓也, 山川直子, 朝日透, 柴田哲男, 大谷文章, 逢坂哲彌

    日本化学会講演予稿集   82nd  2002

    J-GLOBAL

  • Characterization of a Self-Assembled Monolayer of Atropisomeric Compound as a Field for Chiral Discrimination: Enantioselective Adsorption of Phenylalanine.

    中西卓也, 山川直子, 朝日透, 逢坂哲彌, 大谷文章, 魚崎浩平

    日本化学会講演予稿集   81st ( 1 )  2002

    J-GLOBAL

  • ULSI配線用ダマシン銅めっきにおけるフィリング特性の基礎解析

    長谷川円, 中村精一, 横島時彦, 中西卓也, 逢坂哲彌

    表面技術協会講演大会講演要旨集   105th  2002

    J-GLOBAL

  • α-アミノ酸添加により作成した高Bs・高比抵抗CoNiFeC軟磁性薄膜の膜中炭素解析

    志賀大三, 横島時彦, 中西卓也, 逢坂哲彌

    電気化学会大会講演要旨集   69th  2002

    J-GLOBAL

  • Immobilization and crystal growth of glutamic acid on self-assembled monolayers.

    伴野直樹, 中西卓也, 山川直子, 朝日透, 逢坂哲彌

    日本化学会講演予稿集   81st ( 1 )  2002

    J-GLOBAL

  • 高飽和磁束密度を有する電析CoFe磁性薄膜の作製

    今井健太, 志賀大三, 横島時彦, 中西卓也, 逢坂哲彌, 森尻誠

    表面技術協会講演大会講演要旨集   105th  2002

    J-GLOBAL

  • ULSI配線用ダマシン銅めっきのフィリング特性に及ぼす添加剤の効果

    長谷川円, 横島時彦, 中西卓也, 逢坂哲彌

    表面技術協会講演大会講演要旨集   106th  2002

    J-GLOBAL

  • Chiral-selective crystal growth of amino acids on self-assembled monolayer

    伴野直樹, 松永真理子, 中西卓也, 朝日透, 逢坂哲彌

    日本化学会講演予稿集   82nd  2002

    J-GLOBAL

  • ULSIダマシン銅配線用バリア層としての無電解NiBめっきの可能性

    吉野正洋, 野中佑一, 横島時彦, 中西卓也, 逢坂哲彌

    表面技術協会講演大会講演要旨集   106th  2002

    J-GLOBAL

  • 自己組織化単分子層をシード層へ適用した無電解NiReP拡散防止層の作製と評価

    逢坂哲彌, 高野奈央, 黒川哲也, 金子具視, 中西卓也, 上野和良

    電気化学会大会講演要旨集   69th  2002

    J-GLOBAL

  • Effect of C content on properties of electrodeposited CoNiFeMoC soft magnetic thin films

    KAWASHIMA A., YOKOSHIMA T., NAKANISHI T., OSAKA T., OHASHI K.

    日本応用磁気学会学術講演概要集   25   368 - 368  2001.09

    CiNii J-GLOBAL

  • Hydrogen/Deuterium Exchange and Thermal Desorption High-resolution Mass Spectrometry for Probing the Self-Assembled Monolayers Solid-liquid Interface: A Study of Wetting Transition.

    渋江俊道, 中西卓也, 朝日透, 逢坂哲彌

    質量分析総合討論会講演要旨集   49th  2001

    J-GLOBAL

  • α-アミノ酸添加により作成した高Bs・高比抵抗CoNiFeC軟磁性薄膜の熱処理効果及び耐食性

    志賀大三, 水谷聡, 横島時彦, 中西卓也, 逢坂哲彌

    電気化学会大会講演要旨集   68th  2001

    J-GLOBAL

  • 軸不斉化合物自己組織化単分子膜へのキラル選択的アミノ酸吸着挙動

    山川直子, 中西卓也, 朝日透, 逢坂哲彌, 大谷文章, 魚崎浩平

    電気化学秋季大会講演要旨集   2001  2001

    J-GLOBAL

  • Adsorption behavior of chiral amino acids on self-assembled monolayer of atropisomeric compound.

    山川直子, 中西卓也, 朝日透, 逢坂哲彌, 大谷文章, 魚崎浩平

    日本化学会講演予稿集   79th ( 1 )  2001

    J-GLOBAL

  • 軸不斉化合物自己組織化単分子膜修飾QCMによる光学活性アミノ酸吸着挙動の評価

    中西卓也, 山川直子, 朝日透, 逢坂哲彌, 大谷文章, 魚崎浩平

    電気化学会大会講演要旨集   68th  2001

    J-GLOBAL

  • ULSI配線用ダマシンCuめっきにおけるPEGおよび塩化物イオンの影響

    中村精一, 長谷川円, 横島時彦, 中西卓也, 逢坂哲彌

    表面技術協会講演大会講演要旨集   104th  2001

    J-GLOBAL

  • Magnetic properties and thermal stability of electrodeposited CoNiFeMoC soft magnetic thin films with high B_s, and highρ

    KAWASHIMA A., YOKOSHIMA T., SOGAWA Y., NAKANISHI T., OSAKA T., OHASHI K.

    日本応用磁気学会学術講演概要集   24   300 - 300  2000.09

    CiNii J-GLOBAL

  • Increasing the resistivity of electrodeposited CoNiFe soft magnetic thin film by addition of amino acids

    MIZUTANI S., SHIGA D., YOKOSHIMA T., NAKANISHI T., OSAKA T.

    日本応用磁気学会学術講演概要集   24   301 - 301  2000.09

    CiNii J-GLOBAL

  • パルス電析法によるCoNiFe軟磁性薄膜の作製

    中西卓也, NAM H-S., 尾崎昌樹, 横島時彦, 逢坂哲彌

    電気化学会大会講演要旨集   67th  2000

    J-GLOBAL

  • Magnetic properties of electrodepositef high Bs CoNiFe thin film with high resistivity

    KASEDA M., YOSHIMITSU Z., YOKOSHIMA T., NAKANISHI T., OSAKA T.

      23   473 - 473  1999.10

    CiNii J-GLOBAL

  • Increasing the resistivity of electrodeposited CoNiFe soft magnetic thin films by Mo addition.

    SOGAWA Y., KAWASHIMA A., YOKOSHIMA T., NAKANISHI T., OSAKA T., OHASHI K.

      23   472 - 472  1999.10

    CiNii J-GLOBAL

  • 電析法による高Bs CoNiFe軟磁性薄膜の高比抵抗化

    加世田学, 山田昌弘, 横島時彦, 中西卓也, 門間聡之, 逢坂哲彌

    電気化学会大会講演要旨集   66th  1999

    J-GLOBAL

  • 高Bs CoNiFe軟磁性薄膜における磁気特性及び耐食性の検討

    横島時彦, 曽川禎道, 水谷聡, 中西卓也, 門間聡之, 逢坂哲彌

    電気化学会大会講演要旨集   66th  1999

    J-GLOBAL

  • Construction and Characteristic Functions of Thin Layered Film of Semiconductor‐Nanoparticles. Advance in Organic‐Inorganic Composites.

    Takuya Nakanishi, Bunsho Ohtani

    Shokubai (Catalysts & Catalysis)   40 ( 7 ) 552 - 559  1998.10  [Invited]

    CiNii J-GLOBAL

  • Fabrication and characterization of semiconductor-particle monolayers attached on a self-assembled monolayer of alkanedithiol.

    Takuya Nakanishi, Bunsho Ohtani, Kohei Uosaki

    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY   215   U462 - U462  1998.04

    Research paper, summary (international conference)  

  • Preparation and characterization of composite thin multi-layers of semiconductor nanoparticles and alkanethiols.

    大谷文章, 中西卓也, 魚崎浩平

    日本写真学会年次大会講演要旨   1998  1998

    J-GLOBAL

  • Photoelectrochemical Properties of Accumulated Multilayer of Semiconductor Nanoparticles and Thiols.

    大谷文章, 中西卓也, 魚崎浩平

    電気化学会大会講演要旨集   65th  1998

    J-GLOBAL

  • Preparation and characterization of CdS ultrafine particle layer film composited with ZnS ultrafine particle and functional molecule.

    中西卓也, 大谷文章, 魚崎浩平

    日本化学会北海道支部研究発表会講演要旨集   1998  1998

    J-GLOBAL

  • Construction of semiconductor nanoparticle layers on gold by self-assembly technique.

    Bunsho Ohtani, Takuya Nakanishi, Kohei Uosaki

    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY   214   304 - PHYS  1997.09

    Research paper, summary (international conference)  

  • Photoinduced Electron Transfer at Composite Layered films of Inorganic and Organic Materials.

    大谷文章, 中西卓也, 魚崎浩平

    エレクトロオーガニックケミストリー討論会講演要旨集   21st  1997

    J-GLOBAL

  • Structure and Photochemical Property of Alternate Layer-by-Layer Composite Films of CdS Nanoparticle and Alkanedithiol.

    中西卓也, 大谷文章, 魚崎浩平

    日本化学会講演予稿集   73rd  1997

    J-GLOBAL

  • Preparation and Characterization of CdS Nanoparticle/Alkanedithiol Composite Layers on Gold.

    中西卓也, 大谷文章, 魚崎浩平

    電気化学会大会講演要旨集   64th  1997

    J-GLOBAL

  • Preparation and Photochemical Study of Alternate Layer-by-Layer Composite Films of Semiconductor Nanoparticle and Organic Molecule.

    中西卓也, 大谷文章, 魚崎浩平

    コロイドおよび界面化学討論会講演要旨集   50th  1997

    J-GLOBAL

  • Construction of CdS ultrafine particle/dithiol compound layer by self-structuring method.

    中西卓也, 大谷文章, 魚崎浩平

    日本化学会北海道支部研究発表会講演要旨集   1997  1997

    J-GLOBAL

  • アルカリほう酸塩中でのCuの酸化還元

    桜田剛史, 中西卓也, 横川敏雄

    北海道支部研究発表会講演要旨集   1995  1995

    J-GLOBAL

  • 溶融ほう酸塩の酸素電極反応

    高田裕香子, 中西卓也, 横川敏雄

    北海道支部研究発表会講演要旨集   1995  1995

    J-GLOBAL

  • 酸化物融体と金属系のインピーダンス (第4報) 酸化鉄の寄与

    中西卓也, 横川敏雄

    日本金属学会講演概要   114th  1994

    J-GLOBAL

  • Studies on Impedance of Molten Borate Systems. Electrical Conductivity and Oxygen Electrode Reaction.

    中西卓也, 高田裕香子, 横川敏雄

    溶融塩化学討論会要旨集   26th  1994

    J-GLOBAL

  • スラグの酸化還元とインピーダンス (III)

    中西卓也, 山田寿樹, 川崎晋司, 横川敏雄

    日本金属学会講演概要   113th  1993

    J-GLOBAL

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Industrial Property Rights

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