サムエル アショック ザチャリア (サムエル アショック ザチャリア)

写真a

所属

研究院(研究機関) ナノ・ライフ創新研究機構

職名

次席研究員(研究院講師)

学歴 【 表示 / 非表示

  • 2006年01月
    -
    2012年07月

    Indian Institute of Science  

経歴 【 表示 / 非表示

  • 2017年11月
    -
    継続中

    Waseda University

  • 2014年04月
    -
    2017年10月

    National Chiao Tung University

  • 2013年01月
    -
    2014年03月

    学習院大学

所属学協会 【 表示 / 非表示

  • 2019年
    -
    2020年

    International Marine Biotechnology Association

  • 2019年
    -
     

    Chemical Society of Japan

  • 2014年
    -
    2015年

    Chemical Society of Japan

  • 2013年10月
    -
    2014年10月

    Society for Applied Spectroscopy (SAS)

 

研究分野 【 表示 / 非表示

  • 基礎解析学

  • 分子生物学   Raman Imaging, Multivariate analysis

研究キーワード 【 表示 / 非表示

  • Developing analytical methods for general applications of Raman spectroscopy

  • Raman imaging of biological systems

  • Mid IR imaging

  • Fluorescence imaging

  • Raman instrumentation

全件表示 >>

論文 【 表示 / 非表示

  • Deconstruction of Obscure Features in SVD-Decomposed Raman Images from P. chrysogenum Reveals Complex Mixing of Spectra from Five Cellular Constituents

    Ashok Zachariah Samuel, Shumpei Horii, Masahiro Ando, Haruko Takeyama

    Analytical Chemistry   93 ( 35 ) 12139 - 12146  2021年09月

    DOI

  • On Selecting a Suitable Spectral Matching Method for Automated Analytical Applications of Raman Spectroscopy.

    Ashok Zachariah Samuel, Ryo Mukojima, Shumpei Horii, Masahiro Ando, Soshi Egashira, Takuji Nakashima, Masato Iwatsuki, Haruko Takeyama

    ACS omega   6 ( 3 ) 2060 - 2065  2021年01月  [国際誌]

     概要を見る

    Raman spectra are molecular structure-specific and hence are employed in applications requiring chemical identification. The advent of efficient handheld and smartphone-based Raman instruments is promoting widespread applications of the technique, which often involve less trained end users. Software modules that enable spectral library searches based on spectral pattern matching is an essential part of such applications. The Raman spectrum recorded by end users will naturally have varying levels of signal to noise (SN), baseline fluctuations, etc., depending on the sample environment. Further, in biological, forensic, food, pharmaceuticals, etc., fields where a vast amount of Raman spectral data is generated, careful removal of background is often impossible. In other words, a 100% match between the library spectrum and user input cannot be often guaranteed or expected. Often, such influences are discounted upon developing mathematical methods for general applications. In this manuscript, we carefully examine how such effects would determine the results of spectral similarity-based library search. We show that several popular mathematical spectral matching approaches give incorrect results under the influence of small changes in the baseline and/or the noise. We also discuss the points to be carefully considered while generating a spectral library. We believe our results will be a guiding note for developing applications of Raman spectroscopy that uses a standard spectral library and mathematical spectral matching.

    DOI PubMed

  • Molecular profiling of lipid droplets inside HuH7 cells with Raman micro-spectroscopy

    Ashok Zachariah Samuel, Rimi Miyaoka, Masahiro Ando, Anne Gaebler, Christoph Thiele, Haruko Takeyama

    Communications Biology   3 ( 1 )  2020年12月  [査読有り]

    DOI

  • High-Quality Draft Genome Sequence of a Rickettsiales Bacterium Found in Acropora tenuis Coral from Okinawa, Japan.

    Keigo Ide, Yohei Nishikawa, Masato Kogawa, Eisuke Iwamoto, Ashok Zachariah Samuel, Yoshikatsu Nakano, Haruko Takeyama

    Microbiology resource announcements   9 ( 48 )  2020年11月  [国際誌]

     概要を見る

    Rickettsiales-like organisms are important for the survival and functioning of corals, prompting an investigation of their complete genomes. Earlier reports of the genomes of these organisms remain incomplete. Here, we report a novel draft genome of Rickettsiales bacterial strain SESOKO1, found in Acropora tenuis coral, using single-cell genome technology.

    DOI PubMed

  • Draft Genome Sequence of Okeania sp. Strain KiyG1, Assembled from Single-Amplified Genomes Collected from Cape Kiyan, Okinawa, Japan.

    Muhammad Wahyudin Lewaru, Yohei Nishikawa, Keigo Ide, Masato Kogawa, Masahito Hosokawa, Ashok Zachariah Samuel, Shinpei Sumimoto, Handung Nuryadi, Shoichiro Suda, Haruko Takeyama

    Microbiology resource announcements   9 ( 46 )  2020年11月  [国際誌]

     概要を見る

    The genus Okeania is a globally distributed group of microorganisms that live in shallow seabed regions. These organisms play several environmentally important roles and are also known producers of several active secondary metabolites with potential human applications. Here, we present a draft genome of Okeania sp. strain KiyG1 (92.7% completeness) that was assembled from four single-amplified genomes.

    DOI PubMed

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Works(作品等) 【 表示 / 非表示

  • Creations of illusion (https://www.blurb.com/b/7348092-creations-of-illusion)

    Ashok Zachariah Samuel  芸術活動 

    2016年
    -
     

受賞 【 表示 / 非表示

  • Dr. J C GHOSH MEDAL

    2014年03月   Indian Institute of Science  

  • EARLY CAREER RESEARCHER AWARD

    2013年10月   Society for Applied Spectroscopy, USA  

  • JUNIOR RESEARCH FELLOWSHIP

    2005年06月  

  • University First Rank

    2003年05月  

講演・口頭発表等 【 表示 / 非表示

  • Extrusion of extracellular vesicles (EVs) containing a specific secondary metabolite by Penicillium chrysogenum

    Samuel, Ashok Zachariah

    15th Symposium on Biorelevant Chemistry  

    発表年月: 2021年09月

  • A brief journey through Raman Spectroscopy

    Samuel, Ashok Zachariah  [招待有り]

    Analytical Tools in Chemistry  

    発表年月: 2021年08月

  • Extracellular Vesicles Mediate the Release of the Secondary Metabolite Produced by Penicillium chrysogenum

    Samuel, Ashok Zachariah

    World Microbe Forum 2021  

    発表年月: 2021年06月

  • Molecular profiling of lipid droplets inside HuH7 human liver cells with Raman micro-spectroscopy

    Ashok Zachariah Samuel

    5th Core-to-Core International Symposium, Okinawa Institute of Science and Technology, Okinawa, Japan  

    発表年月: 2019年

  • Critical analysis of quantitative molecular profiling of lipid droplets in HuH7cells with Raman micro-spectroscopy and multivariate curve resolution

    Ashok Zachariah Samuel

    10th International Conference on Advanced Vibrational Spectroscopy (ICAVS 10), Auckland, New Zealand  

    発表年月: 2019年

全件表示 >>

 

担当経験のある科目(授業) 【 表示 / 非表示

  • Raman spectroscopy (Fundamentals and applications)

    Waseda University  

    2019年03月
    -
    2019年04月
     

 

学術貢献活動 【 表示 / 非表示

  • Reviews articles for major journals (Chem. Comm, Sci. Rep., Sci. Adv., J. Raman. Spectrosc., Spectroscopy Acta etc.)

    査読等