2022/12/04 更新

写真a

ミヤシタ マサシ
宮下 政司
Scopus 論文情報  
論文数: 0  Citation: 0  h-index: 15

Citation Countは当該年に発表した論文の被引用数

所属
スポーツ科学学術院 スポーツ科学部
職名
教授

他学部・他研究科等兼任情報

  • スポーツ科学学術院   大学院スポーツ科学研究科

  • 附属機関・学校   グローバルエデュケーションセンター

学歴

  •  
    -
    2006年12月

    Loughborough University   School of Sport and Exercise Sciences   博士課程修了  

  •  
    -
    2002年12月

    Loughborough University   School of Sport and Exercise Sciences   修士課程修了  

  •  
    -
    2001年07月

    Loughborough University   Department of Physical Education, Sports Science and Recreation Managemen   学士課程卒業  

学位

  • Loughborough University   博士

経歴

  • 2016年04月
    -
     

    早稲田大学   スポーツ科学学術院   准教授

  • 2012年04月
    -
    2016年03月

    東京学芸大学   芸術・スポーツ科学系 健康スポーツ科学講座   准教授

  • 2009年10月
    -
    2012年03月

    早稲田大学   スポーツ科学学術院   研究院助教

  • 2006年10月
    -
    2009年09月

    筑波大学   大学院人間総合科学研究科   研究員

  • 2006年10月
    -
    2009年09月

    筑波大学   大学院人間総合科学研究科   研究員

所属学協会

  •  
     
     

    日本学校保健学会

  •  
     
     

    韓国運動生理学会

  •  
     
     

    日本咀嚼学会

  •  
     
     

    日本発育発達学会

  •  
     
     

    日本スポーツ栄養学会

  •  
     
     

    ヨーロッパスポーツ科学会

  •  
     
     

    日本健康支援学会

  •  
     
     

    日本動脈硬化学会

  •  
     
     

    日本体力医学会

  •  
     
     

    アメリカスポーツ医学会

▼全件表示

 

研究分野

  • 栄養学、健康科学

  • スポーツ科学

研究キーワード

  • 回復

  • コンディショニング

  • 機能性食品

  • 運動パフォーマンス

  • 食欲調節ホルモン

  • 食欲

  • 体力

  • 子どもの健康

  • 動脈硬化予防

  • 食後代謝

  • エネルギー代謝

  • 身体活動

▼全件表示

論文

  • Energy replacement diminishes the postprandial triglyceride-lowering effect from accumulated walking in older women

    Miyashita M, Hamada Y, Fujihira K, Nagayama C, Takahashi M, Burns SF, Thackray AE, Stensel DJ

    European Journal of Nutrition   59 ( 5 ) 2261 - 2270  2020年01月  [査読有り]

    DOI

    Scopus

    4
    被引用数
    (Scopus)
  • Gum chewing while walking increases fat oxidation and energy expenditure

    Kanno S, Shimo K, Ando T, Hamada Y, Miyashita M, Osawa, K

    Journal of Physical Therapy Science   31 ( 5 ) 435 - 439  2019年04月  [査読有り]

    DOI

  • Effects of increased daily physical activity on mental health and depression biomarkers in postmenopausal women

    Takahashi M, Lim PL, Tsubosaka M, Kim H-Y, Miyashita M, Suzuki K, Tan EL, Shibata S

    Journal of Physical Therapy Science   31 ( 4 ) 408 - 413  2019年04月  [査読有り]  [国内誌]

    DOI PubMed

  • The effects of isomaltulose ingestion on gastric parameters and cycling performance in young men

    Miyashita M, Hamada Y, Fujihira K, Namura S, Sakazaki M, Miyasaka K, Nagai Y

    Journal of Exercise Science and Fitness   17   101 - 107  2019年01月  [査読有り]

  • The effects of water temperature on gastric motility and energy intake in healthy young men

    Fujihira K, Hamada Y, Yanaoka T, Yamamoto R, Suzuki K, Miyashita M

    European Journal of Nutrition    2019年01月  [査読有り]

  • 高濃度茶カテキン継続摂取及びアラニン・プロリン配合ゼリー飲料単回摂取の併用が全身持久力に与える影響

    柳岡拓磨, 降籏泰史, 小泉友範, 井上尚彦, 三原隆一, 太田宣康, 峯岸慶彦, 大塚敦子, 下豊留玲, 城所哲宏, 柏原杏子, 山上隼平, 宮下政司

    日本スポーツ栄養研究誌   12   21 - 32  2019年01月  [査読有り]

  • The effects of gum chewing while walking on physical and physiological functions

    Hamada Y, Yanaoka T, Kashiwabara K, Kurata K, Yamamoto R, Kanno S, Ando T, Miyashita M

    Journal of Physical Therapy Science   30 ( 4 ) 625 - 639  2018年04月  [査読有り]

    DOI

  • Halftime re-warm up with intermittent exercise improves the subsequent exercise performance of soccer referees

    Yanaoka T, Yamagami J, Kashiwabara K, Kidokoro T, Miyashita M

    Journal of Strength and Conditioning Research   32 ( 221 ) 216  2018年  [査読有り]

  • The effect of half-time re-warm up duration on intermittent sprint performance

    Yanaoka T, Kashiwabara K, Masuda Y, Yamagami J, Kurata K, Takagi S, Miyashita M, Hirose N

    Journal of Sports Science and Medicine   17 ( 269 ) 278  2018年  [査読有り]

  • Very-short-duration, low-intensity half-time re-warm up increases subsequent intermittent sprint performance

    Yanaoka T, Hamada Y, Kashiwabara K, Kurata K, Yamamoto R, Miyashita M, Hirose N

    Journal of Strength and Conditioning Research   32 ( 11 ) 3258 - 3266  2018年  [査読有り]

    DOI

    Scopus

    7
    被引用数
    (Scopus)
  • Acute and chronic effects of exercise on appetite, energy intake and appetite-related hormones: the modulating effect of adiposity, sex and habitual physical activity

    Dorling JL, Broom DR, Burns SF, Clayton DJ, Deighton K, James LJ, King JA, Miyashita M, Thackray AE, Batterham RL, Stensel DJ

    Nutrients   10   1140  2018年  [査読有り]

  • 2週間の高濃度茶カテキン含有飲料継続摂取が3000mタイムトライアル評価値に及ぼす影響

    山上隼平, 宮下政司, 城所哲宏, 柳岡拓磨, 柏原杏子, 和氣坂卓也, 松井祐司, 竹下尚男, 大崎紀子, 桂木能久

    日本スポーツ栄養研究誌   11   25 - 32  2018年01月  [査読有り]

  • Different Patterns of Walking and Postprandial Triglycerides in Older Women

    Kyoko Kashiwabara, Tetsuhiro Kidokoro, Takuma Yanaoka, Stephen F. Burns, David J. Stensel, Masashi Miyashita

    Medicine and Science in Sports and Exercise   50 ( 1 ) 79 - 87  2018年01月

     概要を見る

    Purpose: Although a single bout of continuous exercise (Q30 min) reduces postprandial triglyceride (TG), little evidence is available regarding the effect of multiple short (e10 min) bouts of exercise on postprandial TG in individuals at increased risk for cardiovascular diseases. This study compared the effects of different patterns of walking on postprandial TG in postmenopausal, older women with hypertriglyceridemia. Methods: Twelve inactive women (mean age T SD, 71 T 5 yr) with hypertriglyceridemia (fasting TG Q1.70 mmolILj1) completed three, 1-d laboratory-based trials in a random order: 1) control, 2) continuous walking, and 3) multiple short bouts of walking. On the control trial, participants sat in a chair for 8 h. For the walking trials, participants walked briskly in either one 30-min bout in the morning (0900-0930 h) or twenty 90-s bouts over 8 h. Except for walking, both exercise trials mimicked the control trial. In each trial, participants consumed a standardized breakfast (0800 h) and lunch (1100 h). Venous blood samples were collected in the fasted state and at 2, 4, 6, and 8 h after breakfast. Results: The serum TG incremental area under the curve was 35% and 33% lower on the continuous and multiple short bouts of walking trials than that on the control trial (8.2 T 3.1 vs 8.5 T 5.4 vs 12.7 T 5.8 mmol per 8 hILj1, respectively
    main effect of trial: effect size = 0.459, P = 0.001). Conclusions: Accumulating walking in short bouts limits postprandial TG in at-risk, inactive older women with fasting hypertriglyceridemia.

    DOI PubMed

    Scopus

    15
    被引用数
    (Scopus)
  • Acute effect of exercise intensity and duration on acylated ghrelin and hunger in men

    David R. Broom, Masashi Miyashita, Lucy K. Wasse, Richard Pulsford, James A. King, Alice E. Thackray, David J. Stensel

    JOURNAL OF ENDOCRINOLOGY   232 ( 3 ) 411 - 422  2017年03月  [査読有り]

     概要を見る

    Journal of Endocrinology Acute exercise transiently suppresses the orexigenic gut hormone acylated ghrelin, but the extent to which exercise intensity and duration determine this response is not fully understood. The effects of manipulating exercise intensity and duration on acylated ghrelin concentrations and hunger were examined in two experiments. In experiment one, nine healthy males completed three, 4-h conditions (control, moderate-intensity running (MOD) and vigorous-intensity running (VIG)), with an energy expenditure of similar to 2.5 MJ induced in both MOD (55-min running at 52% peak oxygen uptake (VO2peak)) and VIG (36-min running at 75% VO2peak). In experiment two, nine healthy males completed three, 9-h conditions (control, 45-min running (EX45) and 90-min running (EX90)). Exercise was performed at 70% VO2peak. In both experiments, participants consumed standardised meals, and acylated ghrelin concentrations and hunger were quantified at predetermined intervals. In experiment one, delta acylated ghrelin concentrations were lower than control in MOD (ES = 0.44, P = 0.01) and VIG (ES = 0.98, P < 0.001); VIG was lower than MOD (ES = 0.54, P = 0.003). Hunger ratings were similar across the conditions (P = 0.35). In experiment two, delta acylated ghrelin concentrations were lower than control in EX45 (ES = 0.77, P < 0.001) and EX90 (ES = 0.68, P < 0.001); EX45 and EX90 were similar (ES = 0.09, P = 0.55). Hunger ratings were lower than control in EX45 (ES = 0.20, P = 0.01) and EX90 (ES = 0.27, P = 0.001); EX45 and EX90 were similar (ES = 0.07, P = 0.34). Hunger and delta acylated ghrelin concentrations remained suppressed at 1.5h in EX90 but not EX45. In conclusion, exercise intensity, and to a lesser extent duration, are determinants of the acylated ghrelin response to acute exercise.

    DOI

    Scopus

    33
    被引用数
    (Scopus)
  • Effect of different methods of active recovery after high-intensity exercise on intermittent exercise performance of soccer referees

    Yanaoka T, Kidokoro T, Edamoto K, Kashiwabara K, Yamagami J, Miyashita M

    The Journal of Physical Fitness and Sports Medicine.   6 ( 335 ) 342  2017年  [査読有り]

  • Effect of different methods of active recovery after high-intensity exercise on intermittent exercise performance of soccer referees

    Yanaoka Takuma, Kidokoro Tetsuhiro, Edamoto Kanako, Kashiwabara Kyoko, Yamagami Jumpei, Miyashita Masashi

    The Journal of Physical Fitness and Sports Medicine   6 ( 5 ) 335 - 342  2017年

     概要を見る

    <p>This study aimed to examine the effect of different methods of active recovery (AR) after high-intensity exercise on exercise performance, determined with the Yo-Yo Intermittent Recovery Test level 2 (Yo-Yo IR2) in soccer referees. Using a crossover design, fourteen male soccer referees completed three trials. After resting for 10 min, participants ran approximately 495 meters (m) at 80% of maximum heart rate (HRmax) and, ran approximately 165 m at 90% of HRmax. This was followed by 15 min of passive recovery (control), 15 min of running at 130 beats/min (continuous AR), or 15 min of intermittent AR consisting of alternating 2.5 min intervals of passive recovery and running at 130 beats/min, repeated for 15 min (intermittent AR). Finally, participants performed the Yo-Yo IR2. Blood lactate and salivary cortisol concentrations were determined immediately after the rest, high-intensity exercise, recovery intervention and Yo-Yo IR2 periods. The Profile of Mood States (POMS) Questionnaire was measured after rest and Yo-Yo IR2. Yo-Yo IR2 performance was significantly higher in the intermittent AR trial than in the control trial. Blood lactate concentrations were significantly lower in the continuous and intermittent AR trials than in the control trial after the recovery intervention. No significant between-trial differences were observed in salivary cortisol concentrations. The fatigue score using the POMS increased significantly during the control and continuous AR trials, but not during the intermittent AR trial. In conclusion, AR with intermittent exercise after high-intensity exercise increases Yo-Yo IR2 performance compared to passive recovery.</p>

    DOI CiNii

  • グラウンド・ゴルフ実践者と地域在住高齢者におけるロコモ度テストから評価した移動機能の比較

    柏原 杏子, 城所 哲宏, 山上 隼平, 宮下 政司

    理学療法科学   32 ( 4 ) 583 - 587  2017年

     概要を見る

    〔目的〕グラウンド・ゴルフ(以下,GG)実施者の移動機能および身体機能を明らかにすることを目的とした.〔対象と方法〕地域在住高齢者508名を対象として,健康調査を実施した.〔結果〕男女ともに対照群(ORs:1.00)と比較してGG実施群は移動機能の低下が始まっている状態を示すロコモ度1に判定されるオッズ比が低く(男性:0.324,女性:0.315),男性において移動機能の低下が進行している状態を示すロコモ度2に判定されるオッズ比も低いことが明らかとなった(0.277).2ステップテストにおいても対照群と比較してGG実施群が高い値を示した.〔結語〕GG実施者は同年代の高齢者と比較してロコモ度1,2に判定されるリスクが低い.

    DOI CiNii

    Scopus

    1
    被引用数
    (Scopus)
  • 日本人小・中学生における体力および肥満度と血中脂質性状との関連性

    城所 哲宏, 枝元 香菜子, 柳岡 拓磨, 柏原 杏子, 田中 英登, 宮下 政司

    体力科学   66 ( 4 ) 271 - 282  2017年

     概要を見る

    <p>The purpose of the present study was to examine the associations between physical fitness and body fatness with blood lipid profile in 231 Japanese children and adolescents (12.1 ± 1.5 years). The primary outcomes of the present study were a lipid risk score which was calculated by summing up z scores of three lipid items (triglycerides, low density lipoprotein-cholesterol, and high density lipoprotein-cholesterol). Physical fitness was assessed by using the Japanese standardised fitness test. For body fatness, a percentage of overweight was calculated with using age-, sex-, height-specific standardised body mass. For combined analysis (fitness × fatness), the participants were cross-tabulated into four groups (Non-Obese/Higher-Fit, Non-Obese/Lower-Fit, Obese/Higher-Fit, and Obese/Lower-Fit). The results demonstrated that the participants in fitness categories A/B [most fit] and C [middle] demonstrated the lower (better) lipid risk score than the participants in fitness categories D/E [least fit] (F (2, 222) = 6.03, p = .003). For body fatness, the lipid risk score in obese group was significantly higher (worse) than that in thin and normal groups (F (2, 222) = 6.08, p = .004). The combined analysis showed that there was a significant interaction (fitness × fatness) on the lipid risk score (F (1, 221) = 4.05, p = .047), suggesting that Obese/Lower-Fit group had the worst risk score compared to the other groups. The present study suggests that improving both fitness and body fatness might be important for better lipid profile in Japanese children and adolescents.</p>

    DOI CiNii

    Scopus

    1
    被引用数
    (Scopus)
  • 第71回日本体力医学会大会国際セッション参加報告

    宮下 政司

    体力科学   66 ( 1 ) 124 - 124  2017年

    DOI CiNii

  • 2週間の高濃度茶カテキン含有飲料継続摂取が間欠性の運動テストから評価した全身持久力に及ぼす影響:無作為化二重盲検プラセボ対照試験

    山上隼平, 宮下政司, 長谷川雅, 城所哲宏, 柳岡拓磨, 柏原杏子, 和氣坂卓也, 松井祐司, 吉村賢治, 竹下尚男, 安永浩一

    日本スポーツ栄養研究誌   10   17 - 25  2017年01月  [査読有り]

    CiNii

  • Sex-specific associations of moderate and vigorous physical activity with physical fitness in adolescents

    T. Kidokoro, H. Tanaka, K. Naoi, K. Ueno, T. Yanaoka, K. Kashiwabara, M. Miyashita

    European Journal of Sport Science   16 ( 8 ) 1159 - 1166  2016年11月

     概要を見る

    The present study examined the sex-specific associations of moderate and vigorous physical activity (VPA) with physical fitness in 300 Japanese adolescents aged 12–14 years. Participants were asked to wear an accelerometer to evaluate physical activity (PA) levels of various intensities (i.e. moderate PA (MPA), 3–5.9 metabolic equivalents (METs)
    VPA, ≥6 METs
    moderate to vigorous PA (MVPA), ≥3 METs). Eight fitness items were assessed (grip strength, bent-leg sit-up, sit-and-reach, side step, 50 m sprint, standing long jump, handball throw, and distance running) as part of the Japanese standardised fitness test. A fitness composite score was calculated using Japanese fitness norms, and participants were categorised according to their score from category A (most fit) to category E (least fit), with participants in categories D and E defined as having low fitness. It was found that for boys, accumulating more than 80.7 min/day of MVPA may reduce the probability of low fitness (odds ratio (ORs) [95% confidence interval (CI)] = 0.17 [0.06–0.47], p =.001). For girls, accumulating only 8.4 min of VPA could reduce the likelihood of exhibiting low fitness (ORs [95% CI] = 0.23 [0.05–0.89], p =.032). These results reveal that there are sex-specific differences in the relationship between PA and physical fitness in adolescents, suggesting that sex-specific PA recommendation may be needed to improve physical fitness in adolescents.

    DOI PubMed

    Scopus

    7
    被引用数
    (Scopus)
  • Sex-specific associations of moderate and vigorous physical activity with physical fitness in adolescents

    T. Kidokoro, H. Tanaka, K. Naoi, K. Ueno, T. Yanaoka, K. Kashiwabara, M. Miyashita

    EUROPEAN JOURNAL OF SPORT SCIENCE   16 ( 8 ) 1159 - 1166  2016年11月  [査読有り]

     概要を見る

    The present study examined the sex-specific associations of moderate and vigorous physical activity (VPA) with physical fitness in 300 Japanese adolescents aged 12-14 years. Participants were asked to wear an accelerometer to evaluate physical activity (PA) levels of various intensities (i.e. moderate PA (MPA), 3-5.9 metabolic equivalents (METs); VPA, 6 METs; moderate to vigorous PA (MVPA), 3 METs). Eight fitness items were assessed (grip strength, bent-leg sit-up, sit-and-reach, side step, 50m sprint, standing long jump, handball throw, and distance running) as part of the Japanese standardised fitness test. A fitness composite score was calculated using Japanese fitness norms, and participants were categorised according to their score from category A (most fit) to category E (least fit), with participants in categories D and E defined as having low fitness. It was found that for boys, accumulating more than 80.7min/day of MVPA may reduce the probability of low fitness (odds ratio (ORs) [95% confidence interval (CI)]=0.17 [0.06-0.47], p=.001). For girls, accumulating only 8.4min of VPA could reduce the likelihood of exhibiting low fitness (ORs [95% CI]=0.23 [0.05-0.89], p=.032). These results reveal that there are sex-specific differences in the relationship between PA and physical fitness in adolescents, suggesting that sex-specific PA recommendation may be needed to improve physical fitness in adolescents.

    DOI

    Scopus

    7
    被引用数
    (Scopus)
  • Sex-specific associations of moderate and vigorous physical activity with physical fitness in adolescents

    Kidokoro, T, Tanaka, H, Naoi, K, Ueno, K, Yanaoka, T, Kashiwabara, K, Miyashita, M

    European Journal of Sport Science     1 - 8  2016年05月  [査読有り]

     概要を見る

    © 2016 European College of Sport ScienceThe present study examined the sex-specific associations of moderate and vigorous physical activity (VPA) with physical fitness in 300 Japanese adolescents aged 12–14 years. Participants were asked to wear an accelerometer to evaluate physical activity (PA) levels of various intensities (i.e. moderate PA (MPA), 3–5.9 metabolic equivalents (METs); VPA, ≥6 METs; moderate to vigorous PA (MVPA), ≥3 METs). Eight fitness items were assessed (grip strength, bent-leg sit-up, sit-and-reach, side step, 50 m sprint, standing long jump, handball throw, and distance running) as part of the Japanese standardised fitness test. A fitness composite score was calculated using Japanese fitness norms, and participants were categorised according to their score from category A (most fit) to category E (least fit), with participants in categories D and E defined as having low fitness. It was found that for boys, accumulating more than 80.7 min/day of MVPA may reduce the probability of low fitness (odds ratio (ORs) [95% confidence interval (CI)] = 0.17 [0.06–0.47], p = .001). For girls, accumulating only 8.4 min of VPA could reduce the likelihood of exhibiting low fitness (ORs [95% CI] = 0.23 [0.05–0.89], p = .032). These results reveal that there are sex-specific differences in the relationship between PA and physical fitness in adolescents, suggesting that sex-specific PA recommendation may be needed to improve physical fitness in adolescents.

    DOI

    Scopus

    7
    被引用数
    (Scopus)
  • Interrupting Sitting Time with Regular Walks Attenuates Postprandial Triglycerides

    M. Miyashita, K. Edamoto, T. Kidokoro, T. Yanaoka, K. Kashiwabara, M. Takahashi, S. Burns

    INTERNATIONAL JOURNAL OF SPORTS MEDICINE   37 ( 2 ) 97 - 103  2016年02月  [査読有り]

     概要を見る

    We compared the effects of prolonged sitting with the effects of sitting interrupted by regular walking and the effects of prolonged sitting after continuous walking on postprandial triglyceride in postmenopausal women. 15 participants completed 3 trials in random order: 1) prolonged sitting, 2) regular walking, and 3) prolonged sitting preceded by continuous walking. During the sitting trial, participants rested for 8h. For the walking trials, participants walked briskly in either twenty 90-sec bouts over 8h or one 30-min bout in the morning (09:00-09:30). Except for walking, both exercise trials mimicked the sitting trial. In each trial, participants consumed a breakfast (08:00) and lunch (11:00). Blood samples were collected in the fasted state and at 2, 4, 6 and 8h after breakfast. The serum triglyceride incremental area under the curve was 15 and 14% lower after regular walking compared with prolonged sitting and prolonged sitting after continuous walking (4.73 +/- 2.50 vs. 5.52 +/- 2.95 vs. 5.50 +/- 2.59mmol/L.8h respectively, main effect of trial: P=0.023). Regularly interrupting sitting time with brief bouts of physical activity can reduce postprandial triglyceride in postmenopausal women.

    DOI

    Scopus

    42
    被引用数
    (Scopus)
  • 咀嚼と運動からみた消化管ホルモンの変動

    宮下 政司, 柏原 杏子

    体力科学   65 ( 4 ) 367 - 373  2016年

     概要を見る

    Energy balance plays an important role in weight control. Ghrelin is known to stimulate food intake, while peptide YY (PYY) and glucagon-like peptide (GLP-1) are known to suppress food intake. These appetite-related hormones are affected by behaviours such as exercise and mastication. Increasing the number of times food is chewed during a standard meal suppresses ghrelin secretion and food intake. The intensity of exercise is more strongly related to the secretion of total ghrelin, acylated ghrelin, PYY3-36 and food intake than the duration or mode of exercise. This review summarises the effects of exercise and mastication on appetite-related hormones and/or energy intake.

    DOI CiNii

    Scopus

  • Changes in gastrointestinal hormones: The roles of mastication and exercise

    Masashi Miyashita, Kyoko Kashiwabara

    Japanese Journal of Physical Fitness and Sports Medicine   65 ( 4 ) 367 - 373  2016年

     概要を見る

    Energy balance plays an important role in weight control. Ghrelin is known to stimulate food intake, while peptide YY (PYY) and glucagon-like peptide (GLP-1) are known to suppress food intake. These appetite-related hormones are affected by behaviours such as exercise and mastication. Increasing the number of times food is chewed during a standard meal suppresses ghrelin secretion and food intake. The intensity of exercise is more strongly related to the secretion of total ghrelin, acylated ghrelin, PYY3-36 and food intake than the duration or mode of exercise. This review summarises the effects of exercise and mastication on appetiterelated hormones and/or energy intake.

    DOI

    Scopus

  • Interrupting Sitting Time with Regular Walks Attenuates Postprandial Triglycerides

    M. Miyashita, K. Edamoto, T. Kidokoro, T. Yanaoka, K. Kashiwabara, M. Takahashi, S. Burns

    International Journal of Sports Medicine   37 ( 2 ) 97 - 103  2015年10月

     概要を見る

    We compared the effects of prolonged sitting with the effects of sitting interrupted by regular walking and the effects of prolonged sitting after continuous walking on postprandial triglyceride in postmenopausal women. 15 participants completed 3 trials in random order: 1) prolonged sitting, 2) regular walking, and 3) prolonged sitting preceded by continuous walking. During the sitting trial, participants rested for 8 h. For the walking trials, participants walked briskly in either twenty 90-sec bouts over 8 h or one 30-min bout in the morning (09:00-09:30). Except for walking, both exercise trials mimicked the sitting trial. In each trial, participants consumed a breakfast (08:00) and lunch (11:00). Blood samples were collected in the fasted state and at 2, 4, 6 and 8 h after breakfast. The serum triglyceride incremental area under the curve was 15 and 14% lower after regular walking compared with prolonged sitting and prolonged sitting after continuous walking (4.73±2.50 vs. 5.52±2.95 vs. 5.50±2.59 mmol/La·8 h respectively, main effect of trial: P=0.023). Regularly interrupting sitting time with brief bouts of physical activity can reduce postprandial triglyceride in postmenopausal women.

    DOI PubMed

    Scopus

    42
    被引用数
    (Scopus)
  • Effects of breaking sitting by standing and acute exercise on postprandial oxidative stress

    Masaki Takahashi, Masashi Miyashita, Jong-Hwan Park, Shizuo Sakamoto, Katsuhiko Suzuki

    Asian Journal of Sports Medicine   6 ( 3 )  2015年09月

     概要を見る

    Background: Sedentary behavior, which includes sitting and TV viewing, has been identified as an independent risk factor for type 2 diabetes and cardiovascular disease. Breaking sedentary behavior improves metabolic health such as postprandial glycaemia and insulinemia. However, the mechanisms underlying this effect are unclear. Objectives: Here, we examined whether breaking sitting by standing and acute exercise reduces postprandial oxidative stress. Patient and Methods: Fifteen participants performed 3 trials (sitting, standing, and exercise), each lasting 2 days, in a randomised order. On day one of sitting trial, participants sat in a chair. For the standing trial, the participants stood 6 times, for a 45-minute period each time. For the exercise trial, the participants walked or ran at approximately 60% of age-predicted maximum heart rate for 30 minutes. On day two of each trial, participants rested and consumed the standardised breakfast and lunch. Blood samples were collected in the morning and afternoon on day one, and fasting and at 2, 4, and 6 hours postprandially on day two. Results: The concentrations of serum derivatives of reactive oxygen metabolites (d-ROMs) measured at 4 hours (P = 0.064) and 6 hours (P = 0.071) tended to be higher than that in the fasting state in the sitting trial, but not standing and exercise trial (two-factor analysis of variance (ANOVA), trial × time interaction, P = 0.006). Conclusions: Our results indicate the importance of reducing sitting time for improving postprandial oxidative stress status.

    DOI PubMed

    Scopus

    14
    被引用数
    (Scopus)
  • Effects of breaking sitting by standing and acute exercise on postprandial oxidative stress

    Masaki Takahashi, Masashi Miyashita, Jong-Hwan Park, Shizuo Sakamoto, Katsuhiko Suzuki

    Asian Journal of Sports Medicine   6 ( 3 )  2015年09月

     概要を見る

    Background: Sedentary behavior, which includes sitting and TV viewing, has been identified as an independent risk factor for type 2 diabetes and cardiovascular disease. Breaking sedentary behavior improves metabolic health such as postprandial glycaemia and insulinemia. However, the mechanisms underlying this effect are unclear. Objectives: Here, we examined whether breaking sitting by standing and acute exercise reduces postprandial oxidative stress. Patient and Methods: Fifteen participants performed 3 trials (sitting, standing, and exercise), each lasting 2 days, in a randomised order. On day one of sitting trial, participants sat in a chair. For the standing trial, the participants stood 6 times, for a 45-minute period each time. For the exercise trial, the participants walked or ran at approximately 60% of age-predicted maximum heart rate for 30 minutes. On day two of each trial, participants rested and consumed the standardised breakfast and lunch. Blood samples were collected in the morning and afternoon on day one, and fasting and at 2, 4, and 6 hours postprandially on day two. Results: The concentrations of serum derivatives of reactive oxygen metabolites (d-ROMs) measured at 4 hours (P = 0.064) and 6 hours (P = 0.071) tended to be higher than that in the fasting state in the sitting trial, but not standing and exercise trial (two-factor analysis of variance (ANOVA), trial × time interaction, P = 0.006). Conclusions: Our results indicate the importance of reducing sitting time for improving postprandial oxidative stress status.

    DOI

    Scopus

    14
    被引用数
    (Scopus)
  • High-Intensity Interval Exercise and Postprandial Triacylglycerol

    Stephen F. Burns, Masashi Miyashita, David J. Stensel

    SPORTS MEDICINE   45 ( 7 ) 957 - 968  2015年07月  [査読有り]

     概要を見る

    This review examined if high-intensity interval exercise (HIIE) reduces postprandial triacylglycerol (TAG) levels. Fifteen studies were identified, in which the effect of interval exercise conducted at an intensity of &gt;65 % of maximal oxygen uptake was evaluated on postprandial TAG levels. Analysis was divided between studies that included supramaximal exercise and those that included submaximal interval exercise. Ten studies examined the effect of a single session of low-volume HIIE including supramaximal sprints on postprandial TAG. Seven of these studies noted reductions in the postprandial total TAG area under the curve the morning after exercise of between similar to 10 and 21 % compared with rest, but three investigations found no significant difference in TAG levels. Variations in the HIIE protocol used, inter-individual variation or insufficient time post-exercise for an increase in lipoprotein lipase activity are proposed reasons for the divergent results among studies. Five studies examined the effect of high-volume submaximal interval exercise on postprandial TAG. Four of these studies were characterised by high exercise energy expenditure and effectively attenuated total postprandial TAG levels by similar to 15-30 %, but one study with a lower energy expenditure found no effect on TAG. The evidence suggests that supramaximal HIIE can induce large reductions in postprandial TAG levels but findings are inconsistent. Submaximal interval exercise offers no TAG metabolic or time advantage over continuous aerobic exercise but could be appealing in nature to some individuals. Future research should examine if submaximal interval exercise can reduce TAG levels in line with more realistic and achievable exercise durations of 30 min per day.

    DOI PubMed

    Scopus

    8
    被引用数
    (Scopus)
  • Effects of low-carbohydrate and low-fat diets

    Stephen F. Burns, Masashi Miyashita

    Annals of Internal Medicine   162 ( 5 ) 391  2015年03月

    DOI PubMed

    Scopus

  • 第70回日本体力医学会大会国際セッション参加報告

    宮下 政司

    体力科学   64 ( 6 ) 754 - 754  2015年

    DOI CiNii

  • 第69回日本体力医学会大会国際セッション参加報告

    宮下 政司, 荻田 太

    体力科学   64 ( 1 ) 216 - 216  2015年

    CiNii

  • 日常生活下における身体活動の増加が閉経後女性の食後中性脂肪濃度に及ぼす影響

    枝元 香菜子, Jung Hyun-Hun, 城所 哲宏, 柳岡 拓磨, 柏原 杏子, 高橋 将記, 宮下 政司

    体力科学   64 ( 5 ) 485 - 492  2015年

     概要を見る

    Limited evidence was available to support the effect of self-selected activities performed under free-living conditions on postprandial lipaemia, particularly for older adults. Thus, the aim of the present study was to examine the chronic effect of increased physical activity of daily living on postprandial triacylglycerol (TAG) in postmenopausal women. Twenty-eight postmenopausal women, aged 71 ± 4 years (mean ± SD), were randomly divided into two groups: active (n=14) and control (n=14) groups. The participants in the active group were asked to increase their activities above their usual lifestyle levels for 4 weeks; freely deciding the duration and intensity of their chosen activities. The participants in the control group maintained their usual lifestyle for 4 weeks. All participants were asked to wear a uniaxial accelerometer for 4 consecutive weeks. At baseline and after 4 weeks, all participants rested and consumed a standardised breakfast and lunch after a 24-h period of physical activity avoidance. Blood samples were collected in the fasted state (0 h) and at 2, 4 and 6 h after breakfast. After 4 weeks, the participants in the active group increased their step counts by 600 steps/day (from 6979 ± 2057 to 7586 ± 2301 steps/day, p=0.047). There was no difference in the pattern of postprandial TAG response between groups (trial × time interaction, p=0.335). A previous study has suggested that only recent exercise (i.e., 12h before but not 24 h before) appears to facilitate the exercise-induced postprandial TAG lowering effects. Thus, in the present study, postprandial lipaemia was not reduced after performing self-selected activities under free-living in postmenopausal women.

    CiNii

  • The role of physical activity in the prevention of atherosclerosis: Focus on oxidative stress and oxidised low-density lipoprotein

    Masashi Miyashita, Masaki Takahashi, Jong-Hwan Park

    Physical Activity, Exercise, Sedentary Behavior and Health     263 - 272  2015年01月

     概要を見る

    Oxidative stress and inflammatory conditions are associated with an increased risk of atherosclerosis and cardiovascular disease. A large body of evidence supports the notion that higher intensity and/or longer duration exercise training can reduce many cardiovascular disease risk factors including oxidative stress and oxidised low-density lipoprotein. Although physical activity guidelines suggest that adults should engage in at least 150 min of physical activity each week, estimates in many countries suggest that many individuals do not exercise adequately as per guidelines. It is important to determine the minimum level of physical activity required to reduce the risks of cardiovascular disease and atherosclerosis. Thus, the authors conducted a series of investigations to examine the influence of daily physical activity or low-volume exercise training on cardiovascular disease risk factors including oxidative stress markers and oxidised low-density lipoprotein concentration in older adults. We demonstrate that daily physical activity and a low-volume walking program (&lt
    150 min/week) improved oxidative stress status in older adults. The implications of the research findings may encourage more people to incorporate a small amount of physical activity into their lives, and translate to prevention of cardiovascular disease and atherosclerosis in the long term.

    DOI

    Scopus

  • Effect of increased physical activities of daily living on postprandial triacylglycerol concentrations in postmenopausal women

    Kanako Edamoto, Hyun-Hun Jung, Tetsuhiro Kidokoro, Takuma Yanaoka, Kyoko Kashiwabara, Masaki Takahashi, Masashi Miyashita

    Japanese Journal of Physical Fitness and Sports Medicine   64 ( 5 ) 485 - 492  2015年

     概要を見る

    Limited evidence was available to support the effect of self-selected activities performed under free-living conditions on postprandial lipaemia, particularly for older adults. Thus, the aim of the present study was to examine the chronic effect of increased physical activity of daily living on postprandial triacylglycerol (TAG) in postmenopausal women. Twentyeight postmenopausal women, aged 71 ± 4 years (mean ± SD), were randomly divided into two groups: active (n=14) and control (n=14) groups. The participants in the active group were asked to increase their activities above their usual lifestyle levels for 4 weeks
    freely deciding the duration and intensity of their chosen activities. The participants in the control group maintained their usual lifestyle for 4 weeks. All participants were asked to wear a uniaxial accelerometer for 4 consecutive weeks. At baseline and after 4 weeks, all participants rested and consumed a standardised breakfast and lunch after a 24-h period of physical activity avoidance. Blood samples were collected in the fasted state (0 h) and at 2, 4 and 6 h after breakfast. After 4 weeks, the participants in the active group increased their step counts by 600 steps/day (from 6979 ± 2057 to 7586 ± 2301 steps/day, p=0.047). There was no difference in the pattern of postprandial TAG response between groups (trial × time interaction, p=0.335). A previous study has suggested that only recent exercise (i.e., 12h before but not 24 h before) appears to facilitate the exercise-induced postprandial TAG lowering effects. Thus, in the present study, postprandial lipaemia was not reduced after performing self-selected activities under free-living in postmenopausal women.

    DOI

    Scopus

    1
    被引用数
    (Scopus)
  • Increased Participation in Weekend Physical Activity Reduces Postprandial Lipemia in Postmenopausal Women

    M. Miyashita, M. Takahashi, S. Burns

    INTERNATIONAL JOURNAL OF SPORTS MEDICINE   35 ( 13 ) 1059 - 1064  2014年12月  [査読有り]

     概要を見る

    This study examined the acute effect of increased participation in weekend physical activity on postprandial lipemia in postmenopausal women. Ten postmenopausal women, aged 63 +/- 4 years (mean +/- SD), completed 2 trials in a random order: 1) control trial and 2) active trial. In the control trial, participants maintained their usual weekend lifestyle. In the active trial, participants increased their weekend activities above their usual lifestyle levels, freely deciding the duration and intensity of their chosen activities. On Monday of each trial, participants rested and consumed a standardised breakfast and lunch. Capillary blood samples were collected in the fasted state (0h) and at 2, 4 and 6h after eating. In the active trial, participants increased their moderate to vigorous weekend physical activity by 16min (mean +/- SD: 12.3 +/- 6.7min vs. 27.9 +/- 11.9min, P=0.009). Area under the capillary triacylglycerol concentration vs. time curve was 13% lower in the active trial than control trial (8.8 +/- 3.8 vs. 10.1 +/- 3.9mmol/L.6h, P=0.024). These findings demonstrate that small increases in moderate to vigorous physical activity under a real-life setting lowers postprandial lipemia in postmenopausal women.

    DOI

    Scopus

    7
    被引用数
    (Scopus)
  • Acute ingestion of catechin-rich green tea improves postprandial glucose status and increases serum thioredoxin concentrations in postmenopausal women

    Masaki Takahashi, Masashi Miyashita, Katsuhiko Suzuki, Seong-Ryu Bae, Hyeon-Ki Kim, Takuya Wakisaka, Yuji Matsui, Masao Takeshita, Koichi Yasunaga

    British Journal of Nutrition   112 ( 9 ) 1542 - 1550  2014年11月

     概要を見る

    Elevated postprandial hyperglycaemia and oxidative stress increase the risks of type 2 diabetes and CVD. Green tea catechin possesses antidiabetic properties and antioxidant capacity. In the present study, we examined the acute and continuous effects of ingestion of catechin-rich green tea on postprandial hyperglycaemia and oxidative stress in healthy postmenopausal women. Participants were randomly assigned into the placebo (P, n 11) or green tea (GT, n 11) group. The GT group consumed a catechin-rich green tea (catechins 615 mg/350 ml) beverage per d for 4 weeks. The P group consumed a placebo (catechins 92 mg/350 ml) beverage per d for 4 weeks. At baseline and after 4 weeks, participants of each group consumed their designated beverages with breakfast and consumed lunch 3 h after breakfast. Venous blood samples were collected in the fasted state (0 h) and at 2, 4 and 6 h after breakfast. Postprandial glucose concentrations were 3 % lower in the GT group than in the P group (three-factor ANOVA, group × time interaction, P&lt
    0·05). Serum concentrations of the derivatives of reactive oxygen metabolites increased after meals (P&lt
    0·05), but no effect of catechin-rich green tea intake was observed. Conversely, serum postprandial thioredoxin concentrations were 5 % higher in the GT group than in the P group (three-factor ANOVA, group × time interaction, P&lt
    0·05). These findings indicate that an acute ingestion of catechin-rich green tea has beneficial effects on postprandial glucose and redox homeostasis in postmenopausal women.

    DOI PubMed

    Scopus

    43
    被引用数
    (Scopus)
  • Acute ingestion of catechin-rich green tea improves postprandial glucose status and increases serum thioredoxin concentrations in postmenopausal women

    Masaki Takahashi, Masashi Miyashita, Katsuhiko Suzuki, Seong-ryu Bae, Hyeon-Ki Kim, Takuya Wakisaka, Yuji Matsui, Masao Takeshita, Koichi Yasunaga

    BRITISH JOURNAL OF NUTRITION   112 ( 9 ) 1542 - 1550  2014年11月  [査読有り]

     概要を見る

    Elevated postprandial hyperglycaemia and oxidative stress increase the risks of type 2 diabetes and CVD. Green tea catechin possesses antidiabetic properties and antioxidant capacity. In the present study, we examined the acute and continuous effects of ingestion of catechin-rich green tea on postprandial hyperglycaemia and oxidative stress in healthy postmenopausal women. Participants were randomly assigned into the placebo (P, n 11) or green tea (GT, n 11) group. The GT group consumed a catechin-rich green tea (catechins 615 mg/350 ml) beverage per d for 4 weeks. The P group consumed a placebo (catechins 92 mg/350 ml) beverage per d for 4 weeks. At baseline and after 4 weeks, participants of each group consumed their designated beverages with breakfast and consumed lunch 3 h after breakfast. Venous blood samples were collected in the fasted state (0 h) and at 2, 4 and 6 h after breakfast. Postprandial glucose concentrations were 3% lower in the GT group than in the P group (three-factor ANOVA, group x time interaction, P&lt;0.05). Serum concentrations of the derivatives of reactive oxygen metabolites increased after meals (P&lt;0.05), but no effect of catechin-rich green tea intake was observed. Conversely, serum postprandial thioredoxin concentrations were 5% higher in the GT group than in the P group (three-factor ANOVA, group x time interaction, P&lt;0.05). These findings indicate that an acute ingestion of catechin-rich green tea has beneficial effects on postprandial glucose and redox homeostasis in postmenopausal women.

    DOI PubMed

    Scopus

    43
    被引用数
    (Scopus)
  • Increased participation in weekend physical activity reduces postprandial lipemia in postmenopausal women

    M. Miyashita, M. Takahashi, S. Burns

    International Journal of Sports Medicine   35 ( 13 ) 1059 - 1064  2014年06月

     概要を見る

    This study examined the acute effect of increased participation in weekend physical activity on postprandial lipemia in postmenopausal women. Ten postmenopausal women, aged 63±4 years (mean±SD), completed 2 trials in a random order: 1) control trial and 2) active trial. In the control trial, participants maintained their usual weekend lifestyle. In the active trial, participants increased their weekend activities above their usual lifestyle levels, freely deciding the duration and intensity of their chosen activities. On Monday of each trial, participants rested and consumed a standardised breakfast and lunch. Capillary blood samples were collected in the fasted state (0 h) and at 2, 4 and 6 h after eating. In the active trial, participants increased their moderate to vigorous weekend physical activity by 16 min (mean±SD: 12.3±6.7 min vs. 27.9±11.9 min, P=0.009). Area under the capillary triacylglycerol concentration vs. time curve was 13% lower in the active trial than control trial (8.8±3.8 vs. 10.1±3.9 mmol/L 6 h, P=0.024). These findings demonstrate that small increases in moderate to vigorous physical activity under a real-life setting lowers postprandial lipemia in postmenopausal women.

    DOI PubMed

    Scopus

    7
    被引用数
    (Scopus)
  • Effects of Curcumin Supplementation on Exercise-Induced Oxidative Stress in Humans

    M. Takahashi, K. Suzuki, H. K. Kim, Y. Otsuka, A. Imaizumi, M. Miyashita, S. Sakamoto

    INTERNATIONAL JOURNAL OF SPORTS MEDICINE   35 ( 6 ) 469 - 475  2014年06月  [査読有り]

     概要を見る

    The purpose of this study was to investigate the effects of curcumin supplementation on exercise-induced oxidative stress in humans. 10 male participants, ages 26.8 +/- 2.0 years (mean +/- SE), completed 3 trials in a random order: (1) placebo (control), (2) single (only before exercise) and (3) double (before and immediately after exercise) curcumin supplementation trials. Each participant received oral administration of 90 mg of curcumin or the placebo 2 h before exercise and immediately after exercise. Each participant walked or ran at 65 % of (V) over dotO(2max) on a treadmill for 60 min. Blood samples were collected pre-exercise, immediately after exercise and 2 h after exercise. The concentrations of serum derivatives of reactive oxygen metabolites measured immediately after exercise were significantly higher than pre-exercise values in the placebo trial (308.8 +/- 12.9 U. CARR, P &lt; 0.05), but not in the single (259.9 +/- 17.1 U. CARR) or double (273.6 +/- 19.7 U. CARR) curcumin supplementation trials. Serum biological antioxidant potential concentrations measured immediately after exercise were significantly elevated in the single and double curcumin supplementation trials compared with pre-exercise values (P &lt; 0.05). These findings indicate that curcumin supplementation can attenuate exercise-induced oxidative stress by increasing blood antioxidant capacity.

    DOI PubMed

    Scopus

    59
    被引用数
    (Scopus)
  • Low-volume walking program improves cardiovascular-related health in older adults.

    Park Jong-Hwan, Miyashita Masashi, Takahashi Masaki, Kawanishi Noriaki, Hayashida Harumi, Kim Hyun-Shik, Suzuki Katsuhiko, Nakamura Yoshio

    Journal of sports science & medicine   13 ( 3 )  2014年

     概要を見る

    :Although numerous sources of evidence show that regular physical activity is beneficial to health, most individuals do not engage in a sufficient amount of physical activity to meet the guidelines set out by expert panels. In addition, the minimum amount of physical activity associated with reduced cardiovascular disease risk markers is not clear in older adults. The purpose of this study was to determine the effects of a 12-week walking program involving an exercise volume below the current minimum physical activity recommendation on cardiovascular disease risk markers in older adults. The participants were recruited from the following two groups separately: a walking group (n = 14) and a control group (n = 14). In the walking group, participants walked 30 to 60 minutes per session on 2 days per week for 12 weeks (average walking time, 49.4 ± 8.8 min/session). Plasma oxidised low-density lipoprotein concentrations tended to be lower than baseline values in the walking group after 12 weeks (paired t-test, p = 0.127). The ratio of oxidised low-density lipoprotein to high-density lipoprotein cholesterol was significantly lower than the baseline ratio in the walking group after 12 w

    PubMed

  • Effects of curcumin supplementation on exercise-induced oxidative stress in humans.

    Takahashi M, Suzuki K, Kim H K, Otsuka Y, Imaizumi A, Miyashita M, Sakamoto S

    International journal of sports medicine   35 ( 6 )  2014年

     概要を見る

    :The purpose of this study was to investigate the effects of curcumin supplementation on exercise-induced oxidative stress in humans. 10 male participants, ages 26.8±2.0 years (mean±SE), completed 3 trials in a random order: (1) placebo (control), (2) single (only before exercise) and (3) double (before and immediately after exercise) curcumin supplementation trials. Each participant received oral administration of 90 mg of curcumin or the placebo 2h before exercise and immediately after exercise. Each participant walked or ran at 65% of V˙2max on a treadmill for 60min. Blood samples were collected pre-exercise, immediately after exercise and 2h after exercise. The concentrations of serum derivatives of reactive oxygen metabolites measured immediately after exercise were significantly higher than pre-exercise values in the placebo trial (308.8±12.9 U. CARR, P<0.05), but not in the single (259.9±17.1 U. CARR) or double (273.6±19.7 U. CARR) curcumin supplementation trials. Serum biological antioxidant potential concentrations measured immediately after exercise were significantly elevated in the single and double curcumin supplementation trials compared with pre-exercise values (P<0.05). These findings indicate that curcumin supplementation can attenuate exercise-induced oxidative stress by increasing blood antioxidant capacity.

    DOI PubMed

    Scopus

    59
    被引用数
    (Scopus)
  • Low-volume walking program improves cardiovascular-related health in older adults.

    Park Jong-Hwan, Miyashita Masashi, Takahashi Masaki, Kawanishi Noriaki, Hayashida Harumi, Kim Hyun-Shik, Suzuki Katsuhiko, Nakamura Yoshio

    Journal of sports science & medicine   13 ( 3 ) 624 - 631  2014年

     概要を見る

    :Although numerous sources of evidence show that regular physical activity is beneficial to health, most individuals do not engage in a sufficient amount of physical activity to meet the guidelines set out by expert panels. In addition, the minimum amount of physical activity associated with reduced cardiovascular disease risk markers is not clear in older adults. The purpose of this study was to determine the effects of a 12-week walking program involving an exercise volume below the current minimum physical activity recommendation on cardiovascular disease risk markers in older adults. The participants were recruited from the following two groups separately: a walking group (n = 14) and a control group (n = 14). In the walking group, participants walked 30 to 60 minutes per session on 2 days per week for 12 weeks (average walking time, 49.4 ± 8.8 min/session). Plasma oxidised low-density lipoprotein concentrations tended to be lower than baseline values in the walking group after 12 weeks (paired t-test, p = 0.127). The ratio of oxidised low-density lipoprotein to high-density lipoprotein cholesterol was significantly lower than the baseline ratio in the walking group after 12 weeks (paired t-test, p = 0.035). Resting systolic blood pressure and diastolic blood pressure were significantly lower than baseline values in the walking group after 12 weeks (paired t-tests, p = 0.002, p < 0.0005, respectively). Our findings demonstrate that a 12-week walking program comprising a low volume of physical activity confers a benefit to cardiovascular-related health in older adults. Key PointsIt is important to consider baseline physical activity levels when evaluating physical activity program.Being physically active is important to reduce the potential risk marker of cardiovascular disease in older adults.These data imply that a small volume of 12-week walking program confers a benefit to cardiovascular-related health in older adults.

  • Associations between health-related physical fitness and obesity in Taiwanese youth

    Yung Liao, Shao-Hsi Chang, Masashi Miyashita, David Stensel, Jui-Fu Chen, Liang-Tsai Wen, Yoshio Nakamura

    Journal of Sports Sciences   31 ( 16 ) 1797 - 1804  2013年12月

     概要を見る

    This study examined associations between four health-related physical fitness measures and obesity in Taiwanese youth aged 10-18 years. Data from 13,500 school-aged youth were randomly selected from the "School Physical Fitness Database" of Taiwan by sex and age. Variables examined were height, body mass and performance on modified sit-and-reach (flexibility), bent-leg sit-up (abdominal muscular strength/endurance), standing long jump (lower body explosive strength) and distance run/walk (cardiorespiratory endurance). Adjusted logistic regression analyses were performed. Increased odds of being obese with decreased fitness levels were observed for lower body explosive strength and cardiorespiratory endurance in both sexes. The highest odds of being obese was found in the least fit quintile of cardiorespiratory endurance compared with the most fit quintile both in boys (Odds ratio, OR = 10.44
    95% confidence interval (CI), 7.94-13.73) and girls (OR = 5.40
    95% CI, 3.90-7.47). These findings suggest that in addition to cardiorespiratory fitness, lower body explosive strength is also associated with childhood and adolescent obesity. © 2013 Taylor &amp
    Francis.

    DOI PubMed

    Scopus

    30
    被引用数
    (Scopus)
  • Associations between health-related physical fitness and obesity in Taiwanese youth

    Yung Liao, Shao-Hsi Chang, Masashi Miyashita, David Stensel, Jui-Fu Chen, Liang-Tsai Wen, Yoshio Nakamura

    JOURNAL OF SPORTS SCIENCES   31 ( 16 ) 1797 - 1804  2013年12月  [査読有り]

     概要を見る

    This study examined associations between four health-related physical fitness measures and obesity in Taiwanese youth aged 10-18 years. Data from 13,500 school-aged youth were randomly selected from the School Physical Fitness Database of Taiwan by sex and age. Variables examined were height, body mass and performance on modified sit-and-reach (flexibility), bent-leg sit-up (abdominal muscular strength/endurance), standing long jump (lower body explosive strength) and distance run/walk (cardiorespiratory endurance). Adjusted logistic regression analyses were performed. Increased odds of being obese with decreased fitness levels were observed for lower body explosive strength and cardiorespiratory endurance in both sexes. The highest odds of being obese was found in the least fit quintile of cardiorespiratory endurance compared with the most fit quintile both in boys (Odds ratio, OR=10.44; 95% confidence interval (CI), 7.94-13.73) and girls (OR=5.40; 95% CI, 3.90-7.47). These findings suggest that in addition to cardiorespiratory fitness, lower body explosive strength is also associated with childhood and adolescent obesity.

    DOI PubMed

    Scopus

    30
    被引用数
    (Scopus)
  • Low-Volume Exercise Training and Vitamin E Supplementation Attenuates Oxidative Stress in Postmenopausal Women

    Masaki Takahashi, Masashi Miyashita, Jong-Hwan Park, Noriaki Kawanishi, Seong-ryu Bae, Yoshio Nakamura, Shizuo Sakamoto, Katsuhiko Suzuki

    JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY   59 ( 5 ) 375 - 383  2013年10月

     概要を見る

    The purpose of this study was to investigate the effects of low-volume exercise training (90 min/wk) and vitamin E supplementation on oxidative stress markers in postmenopausal women. The participants were non-randomly assigned the following four groups: control (C, n=8), vitamin E (S, n=8), exercise (Ex, n=6), or vitamin E and exercise (S+Ex, n=7). The S and S+Ex groups were instructed to take vitamin E (alpha-tocopherol, 300 mg/d) capsules for 12 wk. The exercise program of Ex and S+Ex groups consisted of walking for a 30-60 min/session 2 d per week for 12 wk. The serum derivatives of reactive oxygen metabolites concentrations were significantly decreased in the Ex, and S+Ex groups after 12 wk compared with the baseline values (three-factor ANOVA, an interaction between exercise and time, p&lt;0.05). Conversely, serum biological antioxidant potential concentrations in the S and Ex groups were significantly higher at 12 wk than at the baseline, but not in the S+Ex group (three-factor ANOVA, an interaction between supplementation, exercise and time, p&lt;0.05). Plasma thioredoxin concentrations in the S, Ex, and S+Ex groups were significantly higher at 12 wk than at the baseline values (three-factor ANOVA, interactions between exercise and time, and between supplementation, exercise and time, p&lt;0.05). Our findings suggest that low-volume physical activity may improve resting oxidative stress status in postmenopausal women.

    CiNii

  • The association between physical activity and sex-specific oxidative stress in older adults

    Takahashi, Masaki, Miyashita, Masashi, Park, Jong Hwan, Kim, Hyun Shik, Nakamura, Yoshio, Sakamoto, Shizuo, Suzuki, Katsuhiko

    Journal of Sports Science and Medicine   12 ( 3 ) 571 - 578  2013年09月

     概要を見る

    Oxidative stress increases with advancing age and is a mediator of several diseases including cancer, cardiovascular disease, and diabetes. Moreover, postmenopausal women have a lower estrogen concentration, which is associated with elevated oxidative stress. However, there is no definitive evidence regarding the relationship between daily physical activity and oxidative stress status in older adults, including postmenopausal women. Twenty- nine adults (age, 70.1 ± 1.0 years, mean ± SE; 12 women and 17 men) were examined in this cross-sectional study. Prior to blood collection, the participants were asked to wear a uniaxial accelerometer for 4 consecutive weeks to determine their level of physical activity. After a 48-h period of physical activity avoidance and a 10-h overnight fast, venous blood samples were obtained from each participant. Fasting plasma derivatives of reactive oxygen metabolites (d-ROMs) and malondialdehyde (MDA) concentrations of oxidative stress markers were negatively correlated with the amount of physical activity in women (d-ROMs; r = -0.708, p = 0.002) (MDA; r = -0.549, p = 0.028), but not in men. Fasting plasma biological antioxidant potential of antioxidant capacity marker was positively correlated with the amount of physical activity in women (BAP; r = 0.657, p = 0.006) (GSH; r = 0.549, p = 0.028), but not in men. Moreover, superoxide dismutase activity of antioxidant capacity marker was positively correlated with the amount of physical activity in men (r = 0.627, p = 0.039), but not in women. There were no associations between physical activity and other oxidative stress markers (reduced and oxidized glutathione, glutathione peroxidise, thioredoxin). These findings suggest that regular physical activity may have a protective effect against oxidative stress by increasing total antioxidant capacity, especially in postmenopausal women. © Journal of Sports Science and Medicine.

  • Effects of intermittent physical activity on fat utilization over a whole day.

    Takafumi Ando, Chiyoko Usui, Kazunori Ohkawara, Rieko Miyake, Masashi Miyashita, Jonghoon Park, Osamu Ezaki, Mitsuru Higuchi, Shigeho Tanaka

    Medicine and science in sports and exercise   45 ( 7 ) 1410 - 8  2013年07月  [国際誌]

     概要を見る

    PURPOSE: We examined whether continuous and intermittent physical activity (PA) differentially influence fat utilization. METHODS: This was a randomized crossover study. Nine healthy young male participants performed two 39-h (two nights, three days) PA sessions (continuous and intermittent exercise) in a respiratory chamber to measure energy expenditure (EE) and substrate oxidation. Participants used a stationary cycling ergometer continuously for 40 min and then 45 min in the continuous PA trial and for 5 min every 30 min 17 times in the intermittent PA trial. They consumed high-carbohydrate meals corresponding to predicted daily total EE for 3 d before entering the respiratory chamber and four high-fat meals corresponding to predicted total EE in the chamber. RESULTS: Twenty-three-hour RER adjusted for sleeping RER on the preceding day was significantly lower in the intermittent PA trial than that in the continuous PA trial (P = 0.021). Twenty-three-hour RER adjusted for sleeping RER on the preceding day was correlated with accumulated consecutive minutes of METs ≤ 1.5 (3 min or more, r = 0.477; 5 min or more, r = 0.510; 10 min or more, r = 0.605). CONCLUSIONS: The intermittent PA trial induced greater fat utilization than the continuous PA trial. The present study, therefore, suggests that intermittent PA has a beneficial effect on 24-h fat oxidation after consumption of a high-fat meal, which may help prevent weight gain over time.

    DOI PubMed

    Scopus

    11
    被引用数
    (Scopus)
  • Effects of different modes of exercise on appetite and appetite-regulating hormones

    Hiroshi Kawano, Mayuko Mineta, Meiko Asaka, Masashi Miyashita, Shigeharu Numao, Yuko Gando, Takafumi Ando, Shizuo Sakamoto, Mitsuru Higuchi

    Appetite   66   26 - 33  2013年07月

     概要を見る

    The present study determined the changes in appetite and appetite-regulating gut hormones during and following bouts of both rope skipping exercise (weight-bearing) and bicycle ergometer exercise (non-weight-bearing). After a 12-h fast, 15 young men (mean ± SD, age 24.4 ± 1.7. yrs, maximal oxygen uptake 47.0 ± 6.5. mL/kg/min) participated in three 160. min trials: (1) rope skipping exercise (295 ± 40. kcal, 3 sets × 10. min with 5-min interval, then rested for 120. min)
    (2) bicycle ergometer exercise (288 ± 36. kcal, 3 sets × 10. min with 5-min interval, then rested for 120. min)
    (3) control (rested for 160. min). Ratings of perceived hunger and acylated ghrelin were suppressed and total peptide YY (PYY) were increased during and immediately after exercise in both exercise trials, but glucagon liked peptide-1 was not changed. Furthermore, suppressed hunger during rope skipping exercise was greater than that during bicycle ergometer exercise, but there were no differences in acylated ghrelin and total PYY. These results indicate that weight-bearing exercise has a greater exercise-induced appetite suppressive effect compared with non-weight-bearing exercise, and both forms of exercise lowered acylated ghrelin and increased total PYY, but the changes did not differ significantly between exercise modes. © 2013 Elsevier Ltd.

    DOI PubMed

    Scopus

    51
    被引用数
    (Scopus)
  • Effects of Intermittent Physical Activity on Fat Utilization over a Whole Day

    Takafumi Ando, Chiyoko Usui, Kazunori Ohkawara, Rieko Miyake, Masashi Miyashita, Jonghoon Park, Osamu Ezaki, Mitsuru Higuchi, Shigeho Tanaka

    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE   45 ( 7 ) 1410 - 1418  2013年07月  [査読有り]

     概要を見る

    Purpose: We examined whether continuous and intermittent physical activity (PA) differentially influence fat utilization. Methods: This was a randomized crossover study. Nine healthy young male participants performed two 39-h (two nights, three days) PA sessions (continuous and intermittent exercise) in a respiratory chamber to measure energy expenditure (EE) and substrate oxidation. Participants used a stationary cycling ergometer continuously for 40 min and then 45 min in the continuous PA trial and for 5 min every 30 min 17 times in the intermittent PA trial. They consumed high-carbohydrate meals corresponding to predicted daily total EE for 3 d before entering the respiratory chamber and four high-fat meals corresponding to predicted total EE in the chamber. Results: Twenty-three-hour RER adjusted for sleeping RER on the preceding day was significantly lower in the intermittent PA trial than that in the continuous PA trial (P = 0.021). Twenty-three-hour RER adjusted for sleeping RER on the preceding day was correlated with accumulated consecutive minutes of METs &lt;= 1.5 (3 min or more, r = 0.477; 5 min or more, r = 0.510; 10 min or more, r = 0.605). Conclusions: The intermittent PA trial induced greater fat utilization than the continuous PA trial. The present study, therefore, suggests that intermittent PA has a beneficial effect on 24-h fat oxidation after consumption of a high-fat meal, which may help prevent weight gain over time.

    DOI PubMed

    Scopus

    11
    被引用数
    (Scopus)
  • Effects of different modes of exercise on appetite and appetite-regulating hormones

    Hiroshi Kawano, Mayuko Mineta, Meiko Asaka, Masashi Miyashita, Shigeharu Numao, Yuko Gando, Takafumi Ando, Shizuo Sakamoto, Mitsuru Higuchi

    Appetite   66   26 - 33  2013年07月

     概要を見る

    The present study determined the changes in appetite and appetite-regulating gut hormones during and following bouts of both rope skipping exercise (weight-bearing) and bicycle ergometer exercise (non-weight-bearing). After a 12-h fast, 15 young men (mean ± SD, age 24.4 ± 1.7. yrs, maximal oxygen uptake 47.0 ± 6.5. mL/kg/min) participated in three 160. min trials: (1) rope skipping exercise (295 ± 40. kcal, 3 sets × 10. min with 5-min interval, then rested for 120. min)
    (2) bicycle ergometer exercise (288 ± 36. kcal, 3 sets × 10. min with 5-min interval, then rested for 120. min)
    (3) control (rested for 160. min). Ratings of perceived hunger and acylated ghrelin were suppressed and total peptide YY (PYY) were increased during and immediately after exercise in both exercise trials, but glucagon liked peptide-1 was not changed. Furthermore, suppressed hunger during rope skipping exercise was greater than that during bicycle ergometer exercise, but there were no differences in acylated ghrelin and total PYY. These results indicate that weight-bearing exercise has a greater exercise-induced appetite suppressive effect compared with non-weight-bearing exercise, and both forms of exercise lowered acylated ghrelin and increased total PYY, but the changes did not differ significantly between exercise modes. © 2013 Elsevier Ltd.

    DOI PubMed

    Scopus

    51
    被引用数
    (Scopus)
  • Effects of low-volume walking programme and vitamin E supplementation on oxidative damage and health-related variables in healthy older adults

    Jong-Hwan Park, Masashi Miyashita, Masaki Takahashi, Noriaki Kawanishi, Seong-Ryu Bae, Hyun-Shik Kim, Katsuhiko Suzuki, Yoshio Nakamura

    NUTRITION & METABOLISM   10 ( 1 )  2013年05月

     概要を見る

    Background: Both exercise and vitamin E supplementation have been shown to reduce oxidative stress and cardiovascular disease risk in older adults, and when combined there is evidence suggesting that they act synergistically. The currently recommended amount of exercise for older adults is 150 min/week of moderate-intensity exercise; however, the minimum amount of exercise necessary to achieve health benefits is not known. The purpose of this study was to investigate the effects of 12 weeks of participation in a low-volume walking exercise programme (i.e. 90 min/week) combined with daily vitamin E supplementation on thiobarbituric acid reactive substances (TBARS) and oxidised low-density lipoprotein (LDL) concentrations in older adults.
    Methods: The participants were recruited from the following four groups separately: 1) control (CG, n = 14), 2) vitamin E supplementation (SG, n = 10), 3) walking (WG, n = 7), or 4) walking + supplementation (WSG, n = 7). In the CG, participants were advised to maintain their normal lifestyle during the study. Participants in both the SG and WSG received 450 IU (300 mg) /day of a-tocopherol for 12 weeks. The exercise programme for the WG and WSG consisted of two 30-60 minute sessions weekly for 12 weeks (average walking time was 44.5 +/- 1.6 min/session). Blood samples were collected at baseline and at 12 weeks.
    Results: Delta plasma oxidised LDL concentrations did not differ among four groups (One-factor ANOVA, P = 0.116). However, negative delta plasma TBARS, a marker of oxidative damage, concentrations were observed in the WG, WSG and SG relative to the CG at the end of the study period (One-factor ANOVA, P = 0.001; post hoc tests; CG compared with WG, WSG and SG, P = 0.005; P = 0.021; P = 0.024, respectively).
    Conclusion: These findings suggest that a low-volume of physical activity and/or vitamin E supplementation may be an effective intervention strategy for reducing TBARS concentrations of older adults.
    Trial registration: UMIN000008304

    DOI PubMed

    Scopus

    8
    被引用数
    (Scopus)
  • Low-volume exercise training attenuates oxidative stress and neutrophils activation in older adults.

    Masaki Takahashi, Masashi Miyashita, Noriaki Kawanishi, Jong-Hwan Park, Harumi Hayashida, Hyun-Shik Kim, Yoshio Nakamura, Shizuo Sakamoto, Katsuhiko Suzuki

    European journal of applied physiology   113 ( 5 ) 1117 - 26  2013年05月  [国際誌]

     概要を見る

    The purpose of this study was to investigate the effects of low-volume exercise training (100 min/week) on oxidative stress and neutrophils activation markers in older adults. Twenty-eight older adults (age range 65-78 years) were assigned into control (n = 14) or exercise (n = 14) groups. The exercise program consisted of walking 30-60 min/session, 2 days each week for 12 weeks. Blood samples were taken before starting the sessions (baseline) and when they ended. Fasting plasma and serum oxidative stress and inflammatory markers were measured using commercial kits. Cell surface expression of adhesion molecules on circulating leukocytes (CD66b and CD62L) was determined using flow cytometry. The concentrations of derivatives of reactive oxygen metabolites tended to be lower than the baseline values only in the exercise group (P = 0.05). The biological antioxidant potential, thioredoxin concentrations, and glutathione peroxidase activities significantly increased only in the exercise group (P < 0.05 for all). While CD66b expression tended to decrease only in the exercise group, CD62L expression significantly increased (P < 0.05). Our findings indicate that exercise training below the current recommended level of at least 150 min/week attenuates basal oxidative stress and neutrophil activation in older adults. Thus, our findings may encourage more people to incorporate a small amount of physical activity into their lives.

    DOI PubMed

    Scopus

    36
    被引用数
    (Scopus)
  • Effects of low-volume walking programme and vitamin E supplementation on oxidative damage and health-related variables in healthy older adults

    Jong-Hwan Park, Masashi Miyashita, Masaki Takahashi, Noriaki Kawanishi, Seong-Ryu Bae, Hyun-Shik Kim, Katsuhiko Suzuki, Yoshio Nakamura

    NUTRITION & METABOLISM   10 ( 1 )  2013年05月

     概要を見る

    Background: Both exercise and vitamin E supplementation have been shown to reduce oxidative stress and cardiovascular disease risk in older adults, and when combined there is evidence suggesting that they act synergistically. The currently recommended amount of exercise for older adults is 150 min/week of moderate-intensity exercise; however, the minimum amount of exercise necessary to achieve health benefits is not known. The purpose of this study was to investigate the effects of 12 weeks of participation in a low-volume walking exercise programme (i.e. 90 min/week) combined with daily vitamin E supplementation on thiobarbituric acid reactive substances (TBARS) and oxidised low-density lipoprotein (LDL) concentrations in older adults.
    Methods: The participants were recruited from the following four groups separately: 1) control (CG, n = 14), 2) vitamin E supplementation (SG, n = 10), 3) walking (WG, n = 7), or 4) walking + supplementation (WSG, n = 7). In the CG, participants were advised to maintain their normal lifestyle during the study. Participants in both the SG and WSG received 450 IU (300 mg) /day of a-tocopherol for 12 weeks. The exercise programme for the WG and WSG consisted of two 30-60 minute sessions weekly for 12 weeks (average walking time was 44.5 +/- 1.6 min/session). Blood samples were collected at baseline and at 12 weeks.
    Results: Delta plasma oxidised LDL concentrations did not differ among four groups (One-factor ANOVA, P = 0.116). However, negative delta plasma TBARS, a marker of oxidative damage, concentrations were observed in the WG, WSG and SG relative to the CG at the end of the study period (One-factor ANOVA, P = 0.001; post hoc tests; CG compared with WG, WSG and SG, P = 0.005; P = 0.021; P = 0.024, respectively).
    Conclusion: These findings suggest that a low-volume of physical activity and/or vitamin E supplementation may be an effective intervention strategy for reducing TBARS concentrations of older adults.
    Trial registration: UMIN000008304

    DOI

    Scopus

    8
    被引用数
    (Scopus)
  • Low-volume exercise training attenuates oxidative stress and neutrophils activation in older adults.

    Masaki Takahashi, Masashi Miyashita, Noriaki Kawanishi, Jong-Hwan Park, Harumi Hayashida, Hyun-Shik Kim, Yoshio Nakamura, Shizuo Sakamoto, Katsuhiko Suzuki

    European journal of applied physiology   113 ( 5 ) 1117 - 26  2013年05月  [国際誌]

     概要を見る

    The purpose of this study was to investigate the effects of low-volume exercise training (100 min/week) on oxidative stress and neutrophils activation markers in older adults. Twenty-eight older adults (age range 65-78 years) were assigned into control (n = 14) or exercise (n = 14) groups. The exercise program consisted of walking 30-60 min/session, 2 days each week for 12 weeks. Blood samples were taken before starting the sessions (baseline) and when they ended. Fasting plasma and serum oxidative stress and inflammatory markers were measured using commercial kits. Cell surface expression of adhesion molecules on circulating leukocytes (CD66b and CD62L) was determined using flow cytometry. The concentrations of derivatives of reactive oxygen metabolites tended to be lower than the baseline values only in the exercise group (P = 0.05). The biological antioxidant potential, thioredoxin concentrations, and glutathione peroxidase activities significantly increased only in the exercise group (P < 0.05 for all). While CD66b expression tended to decrease only in the exercise group, CD62L expression significantly increased (P < 0.05). Our findings indicate that exercise training below the current recommended level of at least 150 min/week attenuates basal oxidative stress and neutrophil activation in older adults. Thus, our findings may encourage more people to incorporate a small amount of physical activity into their lives.

    DOI PubMed

    Scopus

    36
    被引用数
    (Scopus)
  • Effect of one night of sleep deprivation on maximal fat oxidation during graded exercise

    Konishi Masayuki, Takahashi Masaki, Naoya@Endo, NUMAO Shigeharu, TAKAGI Shun, MIYASHITA Masashi, MIDORIKAWA Taishi, SUZUKI Katsuhiko, SAKAMOTO Shizuo

    The journal of physical fitness and sports medicine : JPFSM   2 ( 1 ) 121 - 126  2013年03月

     概要を見る

    The aim of this study was to investigate the effects of one night of sleep deprivation on maximal fat oxidation during a graded exercise test. Ten healthy young males underwent two 2-day control and sleep deprivation trials. Participants were allowed normal sleep from 2300 to 0700 for the control trial, whereas they were required to stay awake for 34 h during the sleep deprivation trial. At 1700 on day 2, participants performed a graded exercise test to exhaustion on a treadmill; this allowed us to determine maximal oxygen uptake and maximal fat oxidation. Before and immediately after the graded exercise test, blood samples were collected in order to measure glucose, insulin, free fatty acid, and triglyceride concentrations. Plasma glucose concentrations were significantly higher in the sleep deprivation trial than in the control trial before the graded exercise test. Serum insulin and free fatty acid concentrations were not significantly different between the two trials. Serum triglyceride concentrations were significantly lower in the sleep deprivation trial than in the control trial. The maximal fat oxidation rate, oxygen uptake, and heart rate at maximal fat oxidation intensity

    DOI CiNii

  • Low-volume exercise training and vitamin E supplementation attenuates oxidative stress in postmenopausal women.

    Takahashi Masaki, Miyashita Masashi, Park Jong-Hwan, Kawanishi Noriaki, Bae Seong-ryu, Nakamura Yoshio, Sakamoto Shizuo, Suzuki Katsuhiko

    Journal of nutritional science and vitaminology   59 ( 5 )  2013年

     概要を見る

    :The purpose of this study was to investigate the effects of low-volume exercise training (90 min/wk) and vitamin E supplementation on oxidative stress markers in postmenopausal women. The participants were non-randomly assigned the following four groups: control (C, n=8), vitamin E (S, n=8), exercise (Ex, n=6), or vitamin E and exercise (S+Ex, n=7). The S and S+Ex groups were instructed to take vitamin E (α-tocopherol, 300 mg/d) capsules for 12 wk. The exercise program of Ex and S+Ex groups consisted of walking for a 30-60 min/session 2 d per week for 12 wk. The serum derivatives of reactive oxygen metabolites concentrations were significantly decreased in the Ex, and S+Ex groups after 12 wk compared with the baseline values (three-factor ANOVA, an interaction between exercise and time, p<0.05). Conversely, serum biological antioxidant potential concentrations in the S and Ex groups were significantly higher at 12 wk than at the baseline, but not in the S+Ex group (three-factor ANOVA, an interaction between supplementation, exercise and time, p<0.05). Plasma thioredoxin concentrations in the S, Ex, and S+Ex groups were significantly higher at 12 wk than at the baseline values (three-factor ANOVA, interactions between exercise and time, and between supplementation, exercise and time, p<0.05). Our findings suggest that low-volume physical activity may improve resting oxidative stress status in postmenopausal women.

    PubMed

  • The association between physical activity and sex-specific oxidative stress in older adults.

    Takahashi Masaki, Miyashita Masashi, Park Jong-Hwan, Kim Hyun-Shik, Nakamura Yoshio, Sakamoto Shizuo, Suzuki Katsuhiko

    Journal of sports science & medicine   12 ( 3 )  2013年

     概要を見る

    :Oxidative stress increases with advancing age and is a mediator of several diseases including cancer, cardiovascular disease, and diabetes. Moreover, postmenopausal women have a lower estrogen concentration, which is associated with elevated oxidative stress. However, there is no definitive evidence regarding the relationship between daily physical activity and oxidative stress status in older adults, including postmenopausal women. Twenty-nine adults (age, 70.1 ± 1.0 years, mean ± SE; 12 women and 17 men) were examined in this cross-sectional study. Prior to blood collection, the participants were asked to wear a uniaxial accelerometer for 4 consecutive weeks to determine their level of physical activity. After a 48-h period of physical activity avoidance and a 10-h overnight fast, venous blood samples were obtained from each participant. Fasting plasma derivatives of reactive oxygen metabolites (d-ROMs) and malondialdehyde (MDA) concentrations of oxidative stress markers were negatively correlated with the amount of physical activity in women (d-ROMs; r = -0.708, p = 0.002) (MDA; r = -0.549, p = 0. 028), but not in men. Fasting plasma biological antioxidant potential of antioxidant capacity marker was positively correlated with the amount of physical activity in women (BAP; r = 0.657, p = 0.006) (GSH; r = 0.549, p = 0.028), but not in men. Moreover, superoxide dismutase activity of antioxidant capacity marker was positively correlated with the amount of physical activity in men (r = 0.627, p = 0.039), but not in women. There were no associations between physical activity and other oxidative stress markers (reduced and oxidized glutathione, glutathione peroxidise, thioredoxin). These findings suggest that regular physical activity may have a protective effect against oxidative stress by increasing total antioxidant capacity, especially in postmenopausal women. Key PointsIt is important to consider daily physical activity status when evaluating antioxidant capacity.Sex differences affect the alteration of oxidative stress markers induced by daily physical activity.Regular physical activity may have a protective effect against oxidative stress by increasing total antioxidant capacity, especially in postmenopausal women.

    PubMed

  • An update on accumulating exercise and postprandial lipaemia: translating theory into practice.

    Miyashita Masashi, Burns Stephen F, Stensel David J

    Journal of preventive medicine and public health = Yebang Ŭihakhoe chi   46 Suppl 1  2013年

     概要を見る

    :Over the last two decades, significant research attention has been given to the acute effect of a single bout of exercise on postprandial lipaemia. A large body of evidence supports the notion that an acute bout of aerobic exercise can reduce postprandial triacylglycerol (TAG) concentrations. However, this effect is short-lived emphasising the important role of regular physical activity for lowering TAG concentrations through an active lifestyle. In 1995, the concept of accumulating physical activity was introduced in expert recommendations with the advice that activity can be performed in several short bouts throughout the day with a minimum duration of 10 minutes per activity bout. Although the concept of accumulation has been widely publicised, there is still limited scientific evidence to support it but several studies have investigated the effects of accumulated activity on health-related outcomes to support the recommendations in physical activity guidelines. One area, which is the focus of this review, is the effect of accumulating exercise on postprandial lipaemia. We propose that accumulating exercise will provide additional physical activity options for lowering postprandial TAG concentrations relevant to individuals with limited time or exercise capacity to engage in more structured forms of exercise, or longer bouts of physical activity. The benefits of accumulated physical activity might translate to a reduced risk of cardiovascular disease in the long-term.

    DOI PubMed

    Scopus

    13
    被引用数
    (Scopus)
  • Effects of sleep deprivation on autonomic and endocrine functions throughout the day and on exercise tolerance in the evening

    Konishi Masayuki, Takahashi Masaki, Kim Hyeon Ki, Endo Naoya, Numao Shigeharu, Takagi Shun, Miyashita Masashi, Midorikawa Taishi, Suzuki Katsuhiko, Sakamoto Shizuo

    体力科学   62 ( 1 ) 69 - 69  2013年

    CiNii

  • An update on accumulating exercise and postprandial lipaemia: Translating theory into practice

    Masashi Miyashita, Stephen F. Burns, David J. Stensel

    Journal of Preventive Medicine and Public Health   46 ( 1 ) S3 - S11  2013年01月

     概要を見る

    Over the last two decades, significant research attention has been given to the acute effect of a single bout of exercise on postprandial lipaemia. A large body of evidence supports the notion that an acute bout of aerobic exercise can reduce postprandial triacylglycerol (TAG) concentrations. However, this effect is short-lived emphasising the important role of regular physical activity for lowering TAG concentrations through an active lifestyle. In 1995, the concept of accumulating physical activity was introduced in expert recommendations with the advice that activity can be performed in several short bouts throughout the day with a minimum duration of 10 minutes per activity bout. Although the concept of accumulation has been widely publicised, there is still limited scientific evidence to support it but several studies have investigated the effects of accumulated activity on health-related outcomes to support the recommendations in physical activity guidelines. One area, which is the focus of this review, is the effect of accumulating exercise on postprandial lipaemia. We propose that accumulating exercise will provide additional physical activity options for lowering postprandial TAG concentrations relevant to individuals with limited time or exercise capacity to engage in more structured forms of exercise, or longer bouts of physical activity. The benefits of accumulated physical activity might translate to a reduced risk of cardiovascular disease in the long-term. Copyright © 2013 The Korean Society for Preventive Medicine.

    DOI PubMed

    Scopus

    13
    被引用数
    (Scopus)
  • The influence of vigorous running and cycling exercise on hunger perceptions and plasma acylated ghrelin concentrations in lean young men

    Lucy K. Wasse, Caroline Sunderland, James A. King, Masashi Miyashita, David J. Stensel

    APPLIED PHYSIOLOGY NUTRITION AND METABOLISM-PHYSIOLOGIE APPLIQUEE NUTRITION ET METABOLISME   38 ( 1 ) 1 - 6  2013年01月

     概要を見る

    Vigorous running suppresses plasma acylated ghrelin concentrations but the limited literature on cycling suggests that acylated ghrelin is unchanged, perhaps because body mass is supported during cycling. It is important from a research and applied perspective to determine whether acylated ghrelin and hunger responses are exercise-mode specific. This study sought to examine this. Eleven recreationally active males fasted overnight and completed three 4-h trials: control, running, and cycling, in a random order. Participants rested throughout the control trial and ran or cycled at 70% of mode-specific maximal oxygen uptake for the first hour during exercise trials, resting thereafter. Hunger was measured every 0.5 h using visual analogue scales. Eight venous blood samples were collected to determine acylated ghrelin concentrations and a standardised meal was consumed at 3 h. Compared with the control trial, acylated ghrelin concentrations were suppressed to a similar extent at 0.5 and 1 h during the running (p &lt; 0.005) and cycling (p &lt; 0.001) trials. Area under the curve values for ghrelin concentration over time were lower during exercise trials versus control (Control: 606 +/- 379; Running: 455 +/- 356; Cycling: 448 +/- 315 pg.mL(-1).4 h(-1); mean +/- SD, p &lt; 0.05). Hunger values did not differ significantly between trials but an interaction effect (p &lt; 0.05) indicated a tendency for hunger to be suppressed during exercise. Thus, at similar relative exercise intensities, plasma acylated ghrelin concentrations are suppressed to a similar extent during running and cycling.

    DOI PubMed

    Scopus

    35
    被引用数
    (Scopus)
  • Postprandial Lipaemia: Effects of Sitting, Standing and Walking in Healthy Normolipidaemic Humans

    M. Miyashita, J. -H. Park, M. Takahashi, K. Suzuki, D. Stensel, Y. Nakamura

    INTERNATIONAL JOURNAL OF SPORTS MEDICINE   34 ( 1 ) 21 - 27  2013年01月

     概要を見る

    Long periods of sedentary behaviour may adversely affect health irrespective of overall physical activity levels. This study compared the effects of sitting, standing and walking on postprandial lipaemia in healthy normolipidaemic Japanese men. 15 participants, aged 26.8 +/- 2.0 years (mean +/- SD), completed 3, 2-day trials in a random order: 1) sitting (control), 2) standing, and 3) walking. On day 1 of the sitting trial, participants rested. On day 1 of the standing trial, participants stood for six, 45-min periods. On day 1 of the walking trial, participants walked briskly for 30 min at approximately 60 % of maximum heart rate. On day 2 of each trial, participants rested and consumed test meals for breakfast and lunch. Venous blood samples were collected in the morning and afternoon on day 1, and in the fasted state (0 h) and at 2, 4 and 6 h postprandially on day 2. On day 2 area under the serum triacylglycerol concentration vs. time curve was 18 % lower on the walking trial than the sitting and standing trials (1-factor ANOVA, P = 0.015). Hence postprandial lipaemia was not reduced after standing but was reduced after low-volume walking compared with sitting in healthy normolipidaemic Japanese men.

    DOI PubMed

    Scopus

    42
    被引用数
    (Scopus)
  • Effects of sleep deprivation on autonomic and endocrine functions throughout the day and on exercise tolerance in the evening

    Masayuki Konishi, Masaki Takahashi, Naoya Endo, Shigeharu Numao, Shun Takagi, Masashi Miyashita, Taishi Midorikawa, Katsuhiko Suzuki, Shizuo Sakamoto

    Journal of Sports Sciences   31 ( 3 ) 248 - 255  2013年

     概要を見る

    The aim of this study was to investigate the effects of sleep deprivation on autonomic and endocrine functions during the day and on exercise tolerance in the evening. Ten healthy young males completed two, 2-day control and sleep deprivation trials. For the control trial, participants were allowed normal sleep from 23:00 to 07:00 h. For the sleep deprivation trial, participants did not sleep for 34 h. Autonomic activity was measured from 19:00 h on day 1 to 16:00 h on day 2 by frequency-domain measures of heart rate variability. Endocrine function was examined by measuring adrenocorticotropic hormone and cortisol from venous blood samples collected on day 2 at 09:00, 13:00, and 17:00 h and immediately after an exercise tolerance testing. Autonomic regulation, particularly parasympathetic regulation estimated from the high-frequency component of heart rate variability analysis, was significantly higher in the sleep deprivation trial than in the control trial in the morning and afternoon of day 2. Plasma adrenocorticotropic hormone concentrations were significantly higher at 09:00 and 13:00 h of day 2 under sleep deprivation. Heart rate during exercise was significantly lower following sleep deprivation. Therefore, the effects of sleep deprivation on autonomic regulation depend on the time of the day. © 2013 Copyright Taylor and Francis Group, LLC.

    DOI PubMed

    Scopus

    14
    被引用数
    (Scopus)
  • Low-volume exercise training and vitamin E supplementation attenuates oxidative stress in postmenopausal women

    Masaki Takahashi, Masashi Miyashita, Jong-Hwan Park, Noriaki Kawanishi, Seong-Ryu Bae, Yoshio Nakamura, Shizuo Sakamoto, Katsuhiko Suzuki

    Journal of Nutritional Science and Vitaminology   59 ( 5 ) 375 - 383  2013年

     概要を見る

    The purpose of this study was to investigate the effects of low-volume exercise training (90 min/wk) and vitamin E supplementation on oxidative stress markers in postmenopausal women. The participants were non-randomly assigned the following four groups: control (C, n=8), vitamin E (S, n=8), exercise (Ex, n=6), or vitamin E and exercise (S+Ex, n=7). The S and S+Ex groups were instructed to take vitamin E (α-tocopherol, 300 mg/d) capsules for 12 wk. The exercise program of Ex and S+Ex groups consisted of walking for a 30-60 min/session 2 d per week for 12 wk. The serum derivatives of reactive oxygen metabolites concentrations were significantly decreased in the Ex, and S+Ex groups after 12 wk compared with the baseline values (three-factor ANOVA, an interaction between exercise and time, p&lt
    0.05). Conversely, serum biological antioxidant potential concentrations in the S and Ex groups were significantly higher at 12 wk than at the baseline, but not in the S+Ex group (three-factor ANOVA, an interaction between supplementation, exercise and time, p&lt
    0.05). Plasma thioredoxin concentrations in the S, Ex, and S+Ex groups were significantly higher at 12 wk than at the baseline values (three-factor ANOVA, interactions between exercise and time, and between supplementation, exercise and time, p&lt
    0.05). Our findings suggest that low-volume physical activity may improve resting oxidative stress status in postmenopausal women.

    DOI PubMed

    Scopus

    8
    被引用数
    (Scopus)
  • Beneficial effects of combined olive oil ingestion and acute exercise on postprandial TAG concentrations in healthy young women

    Chihoko Sasahara, Stephen F. Burns, Masashi Miyashita, David J. Stensel

    BRITISH JOURNAL OF NUTRITION   108 ( 10 ) 1773 - 1779  2012年11月  [査読有り]

     概要を見る

    Foods high in monounsaturated fat, such as olive oil, and endurance exercise are both known to independently reduce postprandial TAG concentrations. We examined the combined effects of exercise and dietary fat composition on postprandial TAG concentrations in nine healthy pre-menopausal females (age 26.8 (SD 3.3) years, BMI 22.3 (SD 2.0) kg/m(2)). Each participant completed four, 2d trials in a randomised order: (1) butter-no exercise, (2) olive oil-no exercise, (3) butter-exercise, (4) olive oil-exercise. On day 1 of the exercise trials, participants walked or ran on a treadmill for 60min. On the no-exercise trials, participants rested on day 1. On day 2 of each trial, participants rested and consumed an olive oil meal (saturated fat 15% and unsaturated fat 85 %) or a butter meal (saturated fat 71% and unsaturated fat 29 %) for breakfast. Venous blood samples were obtained in the fasted state and for 6 h postprandially on day 2. A significant main effect on physical activity (exercise or control) was obtained for plasma TAG concentration (three-way ANOVA, P=0.043), and the total area under the concentration v. time curve for TAG was 26% lower on the olive oil-exercise trial (4.40 (SD 0.40) mmol x 6 h/l) than the butter-no exercise trial (5.91 (SD 1.01) mmol x 6 h/l) (one-way ANOVA, P=0.029). These findings suggest that the combination of exercise and a preference for monounsaturated dietary fat intake in the form of olive oil may be most beneficial for reducing postprandial TAG concentrations.

    DOI PubMed

    Scopus

    6
    被引用数
    (Scopus)
  • Accumulating exercise and postprandial lipaemia

    Miyashita Masashi, Burns Stephen F, Stensel David J

    The journal of physical fitness and sports medicine : JPFSM   1 ( 3 ) 541 - 545  2012年09月

     概要を見る

    Cardiovascular disease is a major cause of death in many developed countries. Impaired clearance of postprandial triacylglycerol has been associated with an increase in cardiovascular disease risk. Physical activity can reduce many cardiovascular disease risk factors including postprandial triacylglycerol concentrations. Public health guidelines suggest that physical activity can be accumulated in several short bouts throughout the day, with a minimum duration of 10 minutes per activity bout. Until recently, limited evidence was available to support the effect of accumulating physical activity on postprandial lipaemia. Thus, the authors conducted a series of investigations to examine the influence of accumulated physical activity on postprandial lipaemia. The implications of the research findings are discussed in keeping with practical guidance for those wishing to engage in exercise that will lower postprandial triacylglycerol concentrations.

    DOI CiNii

  • Psychological, social, and environmental factors associated with utilization of senior centers among older adults in Korea

    Hyun-Shik Kim, Masashi Miyashita, Kazuhiro Harada, Jong-Hwan Park, Jae-Moo So, Yoshio Nakamura

    Journal of Preventive Medicine and Public Health   45 ( 4 ) 244 - 250  2012年07月

     概要を見る

    Objectives: The purpose of the study was to examine the relationships among the psychological, social, and environmental factors influencing the utilization of senior centers among older adults in Korea. Methods: A questionnaire survey was administered to two types of older adults who lived in Seoul, Korea: 262 older adults who used senior centers (3 places) and 156 older adults who did not use senior centers. Results: Our results showed clearly that the utilization of the senior centers in Korea is affected by higher self-efficacy (odds ratio [OR], 6.08
    95% confidence interval [CI], 3.31 to 12.32), higher perceived benefits (OR, 1.71
    95% CI, 1.16 to 4.36), lower perceived barriers (OR, 6.43
    95% CI, 3.07 to 11.45), higher family support (OR, 4.21
    95% CI, 2.02 to 8.77), and higher support from friends (OR, 4.08
    95% CI, 2.38 to 7.81). The results also showed that participants whose total travel time was 15 to 29 minutes (OR, 2.84
    95% CI, 1.21 to 3.64) or less than 14 minutes (OR, 4.68
    95% CI, 3.41 to 8.41) were more likely to use a senior center than those who had to travel more than 30 minutes. Conclusions: This study showed that the utilization of senior centers in Korea is affected by psychological, social, and environmental factors, specifically by self-efficacy, perceived benefits, perceived barriers, social support, convenience of transportation, and total travel time to the senior centers. The effects of longer-term utilization of the senior centers by non-users on health-related outcomes in a large population warrant attention. Copyright © 2012 The Korean Society for Preventive Medicine.

    DOI PubMed

    Scopus

    4
    被引用数
    (Scopus)
  • A 12-week after-school physical activity programme improves endothelial cell function in overweight and obese children: a randomised controlled study

    Jong-Hwan Park, Masashi Miyashita, Yoo-Chan Kwon, Hyun-Tae Park, Eun-Hee Kim, Jin-Kee Park, Ki-Beam Park, Suk-Ran Yoon, Jin-Woong Chung, Yoshio Nakamura, Sang-Kab Park

    BMC PEDIATRICS   12  2012年07月  [査読有り]

     概要を見る

    Background: Endothelial dysfunction is associated with childhood obesity and is closely linked to the amount and function of endothelial progenitor cells. However, it remains unclear whether endothelial progenitor cells increase with after-school exercise in overweight and obese children. The purpose of this study was to investigate the effects of an after-school exercise programme on endothelial cell function in overweight and obese children.
    Methods: A total of 29 overweight/obese children (12.2 +/- 0.1 years) were randomly divided into control (i.e. no after-school exercise, n = 14) and after-school exercise (n = 15) groups. The 12-week after-school exercise intervention consisted of 3 days of combined aerobic and resistance exercise per week. Each 80-minute exercise programme included 10 minutes of warm-up and 10 minutes of cool-down after school. CD34(+) (a cell surface marker on hematopoietic stem cells), CD133(+) (a cell surface marker on hematopoietic progenitor cells) and CD34(+)/CD133(+) (considered as endothelial progenitor cells) were measured at baseline and after 12 weeks using flow cytometry.
    Results: Increased percentages of CD34(+), CD133(+) and CD34(+)/CD133(+) cells were observed in the after-school exercise group (p = 0.018; p = 0.001; p = 0.002, respectively) compared with the control group. Carotid intima-media thickness decreased after 12 weeks in the after-school exercise group (p = 0.020) compared with the control group.
    Conclusions: This study provides preliminary evidence that a combined after-school exercise programme may represent an effective intervention strategy for improving vascular repair and endothelial cell function, leading to improved cardiovascular health in overweight and obese children.

    DOI PubMed

    Scopus

    47
    被引用数
    (Scopus)
  • Effect of weight loss on maximal fat oxidation rate in obese men

    Takehiko Tsujimoto, Hiroyuki Sasai, Masashi Miyashita, Miki Eto, Rina So, Hiroyuki Ohkubo, Kiyoji Tanaka

    OBESITY RESEARCH & CLINICAL PRACTICE   6 ( 2 ) E111 - E119  2012年04月

     概要を見る

    Introduction: The hallmark features of obesity include insulin resistance and an impaired ability to oxidize lipids. As compared to exercise training, it remains relatively unclear if diet-induced weight loss can also induce fat metabolism. This study was undertaken to examine the effects of diet-induced weight loss on fat metabolism during a single session of exercise in middle-aged obese men. Methods: Fifteen obese men who were otherwise healthy (average age of 53.5 +/- 6.9 yr and average body mass index of 27.8 +/- 1.6 kg/m(2)) participated in a 12-wk weight loss program primarily consisting of dietary modification. Maximal fat oxidation (MFO) rates, MFO per lean body mass (MFOLBM) and insulin resistance (HOMA-IR) were measured before and after the program. Participants performed a 24-min graded exercise test on a cycle ergometer, with 15-W increments every 4 min. Expired gas analysis was performed by indirect calorimetry, and nonprotein respiratory quotient equations were used to calculate fat oxidation rates. Results: The weight (-8.3 +/- 3.8 kg), fat mass (-4.5 +/- 1.9 kg), and lean body mass (-3.8 +/- 2.4 kg) (P &lt; 0.001 for all measurements) of the participants were decreased at the end of the 12-wk program. The MFO tended to increase by 19% (P = 0.08) and MFOLBM significantly increased by 28.8% (P = 0.02). Although insulin resistance also significantly decreased by 49% (P &lt; 0.001), changes in fat oxidation variables did not correlate with changes in insulin resistance. Conclusion: Diet-induced weight loss improves fat metabolism with the improvement in insulin resistance. (C) 2011 Asian Oceanian Association for the Study of Obesity. Published by Elsevier Ltd. All rights reserved.

    DOI PubMed

    Scopus

    8
    被引用数
    (Scopus)
  • Appetite after rope skipping may differ between males and females

    Hiroshi Kawano, Fumiya Motegi, Takafumi Ando, Yuko Gando, Mayuko Mineta, Shigeharu Numao, Masashi Miyashita, Shizuo Sakamoto, Mitsuru Higuchi

    OBESITY RESEARCH & CLINICAL PRACTICE   6 ( 2 ) E121 - E127  2012年04月

     概要を見る

    Background: When previously sedentary males and females follow the same exercise training programs with ad libitum feeding, males reduced body mass, but females do not, which suggests that females may increase appetite in response to exercise training compared with males. Rope skipping is traditional exercise modality that everyone had experienced during elementary school years in Japan. The purpose of this study was to determine whether there is a sex difference on appetite after acute rope skipping exercise.
    Methods and results: Thirteen healthy young males (22.5 +/- 0.8 years, 172.2 +/- 1.7 cm, 68.8 +/- 2.3 kg, 18.4 +/- 0.9%) and 13 females (22.9 +/- 0.8 years, 160.6 +/- 1.5 cm, 52.9 +/- 1.6 kg, 25.0 +/- 1.0%) participated in this study. Subjects consumed their lunch by 13:00, and performed a total of 20 min rope skipping exercise (2 sets x 10 min with 5 min interval) from 16:00. In females, appetite significantly increased from immediately after the exercise to 30 min after the exercise (from 13 mm to 30 mm), but remained unchanged in males. Although heart rate, ratings of perceived exertion, and lactate concentrations increased from baseline to immediately after exercise, there were no differences in the increase between males and females. Blood glucose concentrations at baseline and 30 min after exercise were higher in females than in males.
    Conclusion: These results indicated that rope skipping exercise induces an increase in appetite in females, but not in males. This increased appetite in females after the rope skipping exercise was induced without change in blood glucose concentrations. (C) 2011 Asian Oceanian Association for the Study of Obesity. Published by Elsevier Ltd. All rights reserved.

    DOI PubMed

    Scopus

    4
    被引用数
    (Scopus)
  • Appetite after rope skipping may differ between males and females

    Hiroshi Kawano, Fumiya Motegi, Takafumi Ando, Yuko Gando, Mayuko Mineta, Shigeharu Numao, Masashi Miyashita, Shizuo Sakamoto, Mitsuru Higuchi

    OBESITY RESEARCH & CLINICAL PRACTICE   6 ( 2 ) E121 - E127  2012年04月

     概要を見る

    Background: When previously sedentary males and females follow the same exercise training programs with ad libitum feeding, males reduced body mass, but females do not, which suggests that females may increase appetite in response to exercise training compared with males. Rope skipping is traditional exercise modality that everyone had experienced during elementary school years in Japan. The purpose of this study was to determine whether there is a sex difference on appetite after acute rope skipping exercise.
    Methods and results: Thirteen healthy young males (22.5 +/- 0.8 years, 172.2 +/- 1.7 cm, 68.8 +/- 2.3 kg, 18.4 +/- 0.9%) and 13 females (22.9 +/- 0.8 years, 160.6 +/- 1.5 cm, 52.9 +/- 1.6 kg, 25.0 +/- 1.0%) participated in this study. Subjects consumed their lunch by 13:00, and performed a total of 20 min rope skipping exercise (2 sets x 10 min with 5 min interval) from 16:00. In females, appetite significantly increased from immediately after the exercise to 30 min after the exercise (from 13 mm to 30 mm), but remained unchanged in males. Although heart rate, ratings of perceived exertion, and lactate concentrations increased from baseline to immediately after exercise, there were no differences in the increase between males and females. Blood glucose concentrations at baseline and 30 min after exercise were higher in females than in males.
    Conclusion: These results indicated that rope skipping exercise induces an increase in appetite in females, but not in males. This increased appetite in females after the rope skipping exercise was induced without change in blood glucose concentrations. (C) 2011 Asian Oceanian Association for the Study of Obesity. Published by Elsevier Ltd. All rights reserved.

    DOI

    Scopus

    4
    被引用数
    (Scopus)
  • Effect of weight loss on maximal fat oxidation rate in obese men

    Takehiko Tsujimoto, Hiroyuki Sasai, Masashi Miyashita, Miki Eto, Rina So, Hiroyuki Ohkubo, Kiyoji Tanaka

    OBESITY RESEARCH & CLINICAL PRACTICE   6 ( 2 ) E111 - E119  2012年04月

     概要を見る

    Introduction: The hallmark features of obesity include insulin resistance and an impaired ability to oxidize lipids. As compared to exercise training, it remains relatively unclear if diet-induced weight loss can also induce fat metabolism. This study was undertaken to examine the effects of diet-induced weight loss on fat metabolism during a single session of exercise in middle-aged obese men. Methods: Fifteen obese men who were otherwise healthy (average age of 53.5 +/- 6.9 yr and average body mass index of 27.8 +/- 1.6 kg/m(2)) participated in a 12-wk weight loss program primarily consisting of dietary modification. Maximal fat oxidation (MFO) rates, MFO per lean body mass (MFOLBM) and insulin resistance (HOMA-IR) were measured before and after the program. Participants performed a 24-min graded exercise test on a cycle ergometer, with 15-W increments every 4 min. Expired gas analysis was performed by indirect calorimetry, and nonprotein respiratory quotient equations were used to calculate fat oxidation rates. Results: The weight (-8.3 +/- 3.8 kg), fat mass (-4.5 +/- 1.9 kg), and lean body mass (-3.8 +/- 2.4 kg) (P &lt; 0.001 for all measurements) of the participants were decreased at the end of the 12-wk program. The MFO tended to increase by 19% (P = 0.08) and MFOLBM significantly increased by 28.8% (P = 0.02). Although insulin resistance also significantly decreased by 49% (P &lt; 0.001), changes in fat oxidation variables did not correlate with changes in insulin resistance. Conclusion: Diet-induced weight loss improves fat metabolism with the improvement in insulin resistance. (C) 2011 Asian Oceanian Association for the Study of Obesity. Published by Elsevier Ltd. All rights reserved.

    DOI

    Scopus

    8
    被引用数
    (Scopus)
  • A 12-week after-school physical activity programme improves endothelial cell function in overweight and obese children: a randomised controlled study.

    Park Jong-Hwan, Miyashita Masashi, Kwon Yoo-Chan, Park Hyun-Tae, Kim Eun-Hee, Park Jin-Kee, Park Ki-Beam, Yoon Suk-Ran, Chung Jin-Woong, Nakamura Yoshio, Park Sang-Kab

    BMC pediatrics   12  2012年

     概要を見る

    BACKGROUND:Endothelial dysfunction is associated with childhood obesity and is closely linked to the amount and function of endothelial progenitor cells. However, it remains unclear whether endothelial progenitor cells increase with after-school exercise in overweight and obese children. The purpose of this study was to investigate the effects of an after-school exercise programme on endothelial cell function in overweight and obese children.;METHODS:A total of 29 overweight/obese children (12.2 ± 0.1 years) were randomly divided into control (i.e. no after-school exercise, n = 14) and after-school exercise (n = 15) groups. The 12-week after-school exercise intervention consisted of 3 days of combined aerobic and resistance exercise per week. Each 80-minute exercise programme included 10 minutes of warm-up and 10 minutes of cool-down after school. CD34(+) (a cell surface marker on hematopoietic stem cells), CD133(+) (a cell surface marker on hematopoietic progenitor cells) and CD34(+)/CD133(+) (considered as endothelial progenitor cells) were measured at baseline and after 12 weeks using flow cytometry.;RESULTS:Increased percentages of CD34(+), CD133(+) and CD34(+)/CD133(+) cells

    PubMed

  • Effect of Exercise Timing on Postprandial Lipaemia

    Masashi Miyashita, David J. Stensel, Stephen F. Burns

    JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS   19 ( 2 ) 205 - 206  2012年

    CiNii

  • Psychological, social, and environmental factors associated with utilization of senior centers among older adults in Korea.

    Kim Hyun-Shik, Miyashita Masashi, Harada Kazuhiro, Park Jong-Hwan, So Jae-Moo, Nakamura Yoshio

    Journal of preventive medicine and public health = Yebang Ŭihakhoe chi   45 ( 4 )  2012年

     概要を見る

    OBJECTIVES:The purpose of the study was to examine the relationships among the psychological, social, and environmental factors influencing the utilization of senior centers among older adults in Korea.;METHODS:A questionnaire survey was administered to two types of older adults who lived in Seoul, Korea: 262 older adults who used senior centers (3 places) and 156 older adults who did not use senior centers.;RESULTS:Our results showed clearly that the utilization of the senior centers in Korea is affected by higher self-efficacy (odds ratio [OR], 6.08; 95% confidence interval [CI], 3.31 to 12.32), higher perceived benefits (OR, 1.71; 95% CI, 1.16 to 4.36), lower perceived barriers (OR, 6.43; 95% CI, 3.07 to 11.45), higher family support (OR, 4.21; 95% CI, 2.02 to 8.77), and higher support from friends (OR, 4.08; 95% CI, 2.38 to 7.81). The results also showed that participants whose total travel time was 15 to 29 minutes (OR, 2.84; 95% CI, 1.21 to 3.64) or less than 14 minutes (OR, 4.68; 95% CI, 3.41 to 8.41) were more likely to use a senior center than those who had to travel more than 30 minutes.;CONCLUSIONS:This study showed that the utilization of senior centers in Korea is affected by psychological, social, and environmental factors, specifically by self-efficacy, perceived benefits, perceived barriers, social support, convenience of transportation, and total travel time to the senior centers. The effects of longer-term utilization of the senior centers by non-users on health-related outcomes in a large population warrant attention.

    DOI PubMed

    Scopus

    4
    被引用数
    (Scopus)
  • Effect of Exercise Timing on Postprandial Lipaemia

    Masashi Miyashita, David J. Stensel, Stephen F. Burns

    JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS   19 ( 2 ) 205 - 206  2012年  [査読有り]

    DOI PubMed

    Scopus

    1
    被引用数
    (Scopus)
  • Use of senior center and the health-related quality of life in Korean older adults

    Hyun-Shik Kim, Kazuhiro Harada, Masashi Miyashita, Eun-A. Lee, Jin-Kee Park, Yoshio Nakamura

    Journal of Preventive Medicine and Public Health   44 ( 4 ) 149 - 156  2011年07月

     概要を見る

    Objective: The purpose of the present study was to examine the relationship between the use of senior center and health-related quality of life in Korean older adults. Methods: A questionnaire survey was conducted to two types of older adults who lived in Busan, Korea: 154 older adults who used a senior center and 137 older adults who did not use a senior center. The Korean version of short-form 36-item health survey was administered to assess the health-related quality of life. Demographic variables were obtained from a questionnaire. These were gender, age, family status, marital status, education, monthly income, present illness, body mass index and physical activity. Results: The 8-domain scales of physical function and role-physical were significantly higher in the users of the senior center compared with the non-users (F=4.87, p=0.027 and F=7.02, p=0.009, respectively). The 8-domain scales of vitality was also significantly higher in the users of the senior center compared with the non-users (F=7.48, p=0.007). Conclusions: The present study showed that the users of the senior center have higher physical function, role-physical and vitality compared with the non-users. These findings suggest that although the results are unable to specify causal relationships using the senior center may lead to some improvement in health-related quality of life.

    DOI PubMed

    Scopus

    16
    被引用数
    (Scopus)
  • The effects of 30 min of exercise on cardiovascular disease risk factors in healthy and obese individuals

    Masashi Miyashita, David J. Stensel, Stephen F. Burns, Hiroyuki Sasai, Kiyoji Tanaka

    ATHEROSCLEROSIS   216 ( 2 ) 496 - 497  2011年06月

    DOI PubMed

    Scopus

  • 断眠の交感神経副腎髄質系およびHPA系に及ぼす影響 : 唾液中ストレス指標による検討

    小西 真幸, 高橋 将記, 遠藤 直哉, 沼尾 成晴, 高木 俊, 宮下 政司, 緑川 泰史, 鈴木 克彦, 坂本 静男

    日本臨床生理学会雑誌 = Japanese journal of applied physiology   41 ( 3 ) 129 - 135  2011年06月

    CiNii

  • 第65回日本体力医学会国際セッション : 報告レポート

    宮下 政司

    体力科學   60 ( 1 ) 88 - 88  2011年02月

    DOI CiNii

  • Physical activity status and postprandial lipaemia in older adults

    M. Miyashita, J. H. Park, M. Takahashi, S. Burns, H. S. Kim, K. Suzuki, Y. Nakamura

    International Journal of Sports Medicine   32 ( 11 ) 829 - 834  2011年

     概要を見る

    Physical activity-induced lowering of postprandial lipaemia is short-lived. However, little is known regarding the role of physical activity status on postprandial lipaemia. The purpose of the present study was to compare postprandial triacylglycerol concentrations in active and inactive older adults. A total of 26 older adults (aged 69.8±0.9 years, mean±SEM
    10 male and 16 female) were analysed in a cross-sectional design. Based on accelerometer data, participants were divided into either the active group (150min/week of moderate-intensity physical activity, n=15) or the inactive group (&lt
    150min/week of moderate-intensity physical activity, n=11). After a 48-h period of physical activity avoidance and a 10-h overnight fast, participants consumed a test meal of moderate fat content (35%). Capillary blood samples were collected in the fasted state and at 2, 4, and 6h postprandially. After adjusting for fasting triacylglycerol concentrations, body mass, body mass index and waist circumference, postprandial capillary triacylglycerol concentrations were significantly lower in the active than inactive group (P=0.046). These findings demonstrate that regular physical activity lowers postprandial lipaemia independent of the acute effects of physical activity in older adults. © Georg Thieme Verlag KG Stuttgart · New York.

    DOI PubMed

    Scopus

    11
    被引用数
    (Scopus)
  • Accumulating short bouts of running reduces resting blood pressure in young normotensive/pre-hypertensive men

    Masashi Miyashita, Stephen F. Burns, David J. Stensel

    Journal of Sports Sciences   29 ( 14 ) 1473 - 1482  2011年

     概要を見る

    In this study, we compared the effects of accumulated and continuous running on resting arterial blood pressure. Ten normotensive/pre-hypertensive men, aged 25.0 ± 4.2 years (mean ± s), participated in three 2-day trials at least one week apart in a randomized, repeated-measures design. On Day 1, participants rested (control) or ran at 70% of maximum oxygen uptake in either ten 3-min bouts (30 min rest between bouts) or one continuous 30-min bout. On Day 2, participants rested throughout the day. Blood pressure was measured at hourly intervals throughout Days 1 and 2. Mean resting systolic blood pressure on Day 2 was 6% lower during the accumulated and continuous running trials compared with the control trial (110 ± 6 vs. 110 ± 8 vs. 117 ± 6 mmHg respectively
    P &lt
    0.05), but there were no differences in resting diastolic blood pressure among the three trials (70 ± 7 vs. 69 ± 6 vs. 70 ± 5 mmHg respectively). These findings demonstrate that accumulating 30 min of running throughout the day in short bouts is as effective as 30 min of continuous running for reducing resting systolic blood pressure on the next day in young normotensive/pre-hyptertensive men. © 2011 Taylor &amp
    Francis Group, LLC.

    DOI PubMed

    Scopus

    12
    被引用数
    (Scopus)
  • Use of senior center and the health-related quality of life in Korean older adults.

    Kim Hyun Shik, Harada Kazuhiro, Miyashita Masashi, Lee Eun A, Park Jin Kee, Nakamura Yoshio

    Journal of preventive medicine and public health = Yebang Ŭihakhoe chi   44 ( 4 )  2011年

     概要を見る

    OBJECTIVE:The purpose of the present study was to examine the relationship between the use of senior center and health-related quality of life in Korean older adults.;METHODS:A questionnaire survey was conducted to two types of older adults who lived in Busan, Korea: 154 older adults who used a senior center and 137 older adults who did not use a senior center. The Korean version of short-form 36-item health survey was administered to assess the health-related quality of life. Demographic variables were obtained from a questionnaire. These were gender, age, family status, marital status, education, monthly income, present illness, body mass index and physical activity.;RESULTS:The 8-domain scales of physical function and role-physical were significantly higher in the users of the senior center compared with the non-users (F=4.87, p=0.027 and F=7.02, p=0.009, respectively). The 8-domain scales of vitality was also significantly higher in the users of the senior center compared with the non-users (F=7.48, p=0.007).;CONCLUSIONS:The present study showed that the users of the senior center have higher physical function, role-physical and vitality compared with the non-users. These findings suggest that although the results are unable to specify causal relationships using the senior center may lead to some improvement in health-related quality of life.

    DOI PubMed

    Scopus

    16
    被引用数
    (Scopus)
  • Oxidised low-density lipoprotein concentrations and physical activity status in older adults: the WASEDA active life study.

    Park Jong-Hwan, Miyashita Masashi, Takahashi Masaki, Harada Kazuhiro, Takaizumi Kanae, Kim Hyun-Shik, Suzuki Katsuhiko, Nakamura Yoshio

    Journal of atherosclerosis and thrombosis   18 ( 7 )  2011年

     概要を見る

    AIM:Oxidised low-density lipoprotein (LDL) is considered a risk marker for cardiovascular disease. However, it remains unclear whether oxidised LDL concentrations differ with the physical activity status in older adults. The purpose of this study was to examine the relationship between the amount of physical activity and oxidised LDL in older adults.;METHODS:Twenty-seven older adults (aged 69.9 ± 4.3 years, mean ± SD.; 16 female and 11 male) were analysed in the cross-sectional design. Prior to blood collection, participants were asked to wear an uniaxial accelerometer for 4 consecutive weeks to determine the physical activity status. After a 48-h period of physical activity avoidance and a 10-h overnight fast, fasting venous blood samples were obtained from each participant.;RESULTS:Fasting plasma oxidised LDL concentrations and plasma monocyte chemoattractant pro-tein-1 concentrations were negatively correlated with the amount of physical activity (r=-0.409, p=0.034; r=-0.385, p=0.047, respectively).;CONCLUSIONS:This study demonstrates that regular physical activity may play a protective role in the oxidation of LDL in older adults.

    PubMed

  • Oxidised Low-Density Lipoprotein Concentrations and Physical Activity Status in Older Adults: The WASEDA Active Life Study

    Jong-Hwan Park, Masashi Miyashita, Masaki Takahashi, Kazuhiro Harada, Kanae Takaizumi, Hyun-Shik Kim, Katsuhiko Suzuki, Yoshio Nakamura

    JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS   18 ( 7 ) 568 - 573  2011年

     概要を見る

    Aim: Oxidised low-density lipoprotein (LDL) is considered a risk marker for cardiovascular disease. However, it remains unclear whether oxidised LDL concentrations differ with the physical activity status in older adults. The purpose of this study was to examine the relationship between the amount of physical activity and oxidised LDL in older adults.
    Methods: Twenty-seven older adults (aged 69.9 +/- 4.3 years, mean +/- SD.; 16 female and 11 male) were analysed in the cross-sectional design. Prior to blood collection, participants were asked to wear an uniaxial accelerometer for 4 consecutive weeks to determine the physical activity status. After a 48-h period of physical activity avoidance and a 10-h overnight fast, fasting venous blood samples were obtained from each participant.
    Results: Fasting plasma oxidised LDL concentrations and plasma monocyte chemoattractant protein-1 concentrations were negatively correlated with the amount of physical activity (r = -0.409, p = 0.034; r = -0.385, p = 0.047, respectively).
    Conclusions: This study demonstrates that regular physical activity may play a protective role in the oxidation of LDL in older adults.

    DOI PubMed CiNii

    Scopus

    5
    被引用数
    (Scopus)
  • Accumulating short bouts of running reduces resting blood pressure in young normotensive/pre-hypertensive men

    Masashi Miyashita, Stephen F. Burns, David J. Stensel

    JOURNAL OF SPORTS SCIENCES   29 ( 14 ) 1473 - 1482  2011年

     概要を見る

    In this study, we compared the effects of accumulated and continuous running on resting arterial blood pressure. Ten normotensive/pre-hypertensive men, aged 25.0 +/- 4.2 years (mean +/- s), participated in three 2-day trials at least one week apart in a randomized, repeated-measures design. On Day 1, participants rested (control) or ran at 70% of maximum oxygen uptake in either ten 3-min bouts (30 min rest between bouts) or one continuous 30-min bout. On Day 2, participants rested throughout the day. Blood pressure was measured at hourly intervals throughout Days 1 and 2. Mean resting systolic blood pressure on Day 2 was 6% lower during the accumulated and continuous running trials compared with the control trial (110 +/- 6 vs. 110 +/- 8 vs. 117 +/- 6 mmHg respectively; P &lt; 0.05), but there were no differences in resting diastolic blood pressure among the three trials (70 +/- 7 vs. 69 +/- 6 vs. 70 +/- 5 mmHg respectively). These findings demonstrate that accumulating 30 min of running throughout the day in short bouts is as effective as 30 min of continuous running for reducing resting systolic blood pressure on the next day in young normotensive/pre-hyptertensive men.

    DOI PubMed

    Scopus

    12
    被引用数
    (Scopus)
  • 有酸素性運動と非空腹時(食後)中性脂肪 : 基礎から応用への展開(運動強度と呼吸・循環・代謝・筋骨格系,シンポジウム,04.運動生理学,専門分科会企画)

    宮下 政司

    日本体育学会大会予稿集   61 ( 61 ) 39 - 39  2010年09月

    DOI CiNii

  • 運動における食後中性脂肪の上昇抑制効果 : 最近の実証研究からの報告

    宮下 政司

    肥満研究 : 日本肥満学会誌 = Journal of Japan Society for the Study of Obesity   16 ( 2 ) 100 - 104  2010年08月

    CiNii

  • Influence of prolonged treadmill running on appetite, energy intake and circulating concentrations of acylated ghrelin

    James A. King, Masashi Miyashita, Lucy K. Wasse, David J. Stensel

    Appetite   54 ( 3 ) 492 - 498  2010年06月

     概要を見る

    The effects of prolonged treadmill running on appetite, energy intake and acylated ghrelin (an appetite stimulating hormone) were examined in 9 healthy males over the course of 24. h. Participants completed 2 experimental trials (exercise and control) in a randomised-crossover fashion. In the exercise trial participants ran for 90. min at 68.8 ± 0.8% of maximum oxygen uptake followed by 8.5. h of rest. Participants returned to the laboratory on the following morning to provide a fasting blood sample and ratings of appetite (24. h measurement). No exercise was performed on the control trial. Appetite was measured within the laboratory using visual analogue scales and energy intake was assessed from ad libitum buffet meals. Acylated ghrelin was determined from plasma using an ELISA assay. Exercise transiently suppressed appetite and acylated ghrelin but each remained no different from control values in the hours afterwards. Furthermore, despite participants expending 5324. kJ during exercise there was no compensatory increase in energy intake (24. h energy intake
    control 17,191. kJ, exercise 17,606. kJ). These findings suggest that large energy deficits induced by exercise do not lead to acute compensatory responses in appetite, energy intake or acylated ghrelin. © 2010 Elsevier Ltd.

    DOI PubMed

    Scopus

    119
    被引用数
    (Scopus)
  • 生活指導の立場から : 肥満に対する運動と食事療法の寄与度について

    宮下 政司, 田中 喜代次

    日本臨床スポーツ医学会誌 = The journal of Japanese Society of Clinical Sports Medicine   18 ( 2 ) 251 - 253  2010年04月

    CiNii

  • Twelve-Week Jogging Training Increases Pre-Heparin Serum Lipoprotein Lipase Concentrations in Overweight/Obese Middle-Aged Men

    Masashi Miyashita, Miki Eto, Hiroyuki Sasai, Takehiko Tsujimoto, Yasuhiro Nomata, Kiyoji Tanaka

    JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS   17 ( 1 ) 21 - 29  2010年

     概要を見る

    Aim: Enhancement of lipoprotein lipase (LPL) activity through drug administration has been shown to increase pre-heparin serum LPL concentrations; however, pre-heparin serum LPL responses to exercise training have not been determined. The present study was undertaken to investigate the effects of 12 weeks of supervised aerobic exercise training on pre-heparin serum LPL concentrations in overweight/obese men.
    Methods: Fifteen overweight/obese middle-aged men were assigned to one of two 12-week supervised exercise interventions: a walking group (eight participants gradually increasing brisk walking to 60 min/day 3 days a week) or a jogging group (seven participants gradually increasing jogging to 60 min/day 3 days a week). All participants maintained ad libitum diets. Blood samples were collected at baseline and immediately after 12 weeks. The primary outcome was pre-heparin serum LPL.
    Results: Pre-heparin serum LPL concentrations were increased in the jogging group after 12 weeks compared with the baseline values (mean +/- SEM: 37.6 +/- 4.7 vs. 51.0 +/- 6.6 ng/mL, respectively, p = 0.033). In the walking group, pre-heparin serum LPL concentrations remained unchanged after 12 weeks.
    Conclusions: This study demonstrates that 12 weeks of jogging training increases pre-heparin serum LPL concentrations in overweight/obese middle-aged men.

    CiNii

  • Pre-Heparin Serum Lipoprotein Lipase Concentrations in Obese Men of Contrasting Physical Activity Status: A Preliminary Study

    Masashi Miyashita, Miki Eto, Hiroyuki Sasai, Takehiko Tsujimoto, Rina So, Yasuhiro Nomata, Kiyoji Tanaka

    JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS   17 ( 10 ) 1110 - 1112  2010年  [査読有り]

    PubMed CiNii

  • Post-prandial capillary triacylglycerol responses to moderate exercise in centrally obese middle-aged men

    Masashi Miyashita, Hiroyuki Sasai, Kiyoji Tanaka

    JOURNAL OF SPORTS SCIENCES   28 ( 12 ) 1269 - 1275  2010年  [査読有り]

     概要を見る

    In this study, we wished to determine whether 30min of moderate-intensity exercise, corresponding to minimal recommended guidelines, attenuates post-prandial capillary triacylglycerol concentrations in obese men. Ten middle-aged, centrally obese men (age 46 +/- 2 years, body mass index 31.6 +/- 1.0kg center dot m-2, waist circumference 104.6 +/- 2.2cm) completed two 2-day trials (exercise and control) at least one week apart in a randomized, repeated-measures design. On day 1, participants either cycled for 30min at approximately 60% of maximal heart rate in the afternoon or rested (no exercise). On day 2 of both trials, after a 10-h overnight fast, participants consumed a test meal of moderate fat content (35%) for breakfast. Capillary blood samples were collected in the fasted state (0h) and at 2, 4, and 6h post-prandially on day 2. Total area under the capillary triacylglycerol concentration versus time curve was significantly lower on the exercise than control trial (P=0.023). One 30-min session of moderate-intensity cycling is effective in lowering post-prandial capillary triacylglycerol concentration in obese middle-aged men. These findings may have important implications for exercise recommendations as a means to reduce the risk of cardiovascular disease if such exercise is performed for an extended period.

    DOI PubMed

    Scopus

    11
    被引用数
    (Scopus)
  • Acute Effects of Accumulating Exercise on Postprandial Lipemia and C-Reactive Protein Concentrations in Young Men

    Masashi Miyashita, Stephen F. Burns, David J. Stensel

    INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM   19 ( 6 ) 569 - 582  2009年12月  [査読有り]

     概要を見る

    The current study investigated the acute effects of accumulating short bouts of running on circulating concentrations of postprandial triacylglycerol (TAG) and C-reactive protein (CRP). Ten men, age 21-32 yr, completed two 1-d trials. On 1 occasion participants ran at 70% of maximum oxygen uptake in six 5-min bouts (i.e., 8:30, 10, and 11:30 a.m. and 1, 2:30, and 4 p.m.) with 85 min rest between runs. On another occasion participants rested throughout the day. In both trials, participants consumed test meals at 9 a.m. and 12 p.m. In each trial, venous blood samples were collected at 8:30, 10, and 11:30 a.m. and 1, 2:30, 4, and 5:30 p.m. for plasma TAG measurement and at 8:30 a.m. and 5:30 p.m. for serum CRP measurement. Total area under the curve for plasma TAG concentration versus time was 10% lower on the exercise trial than the control trial (M +/- SEM: 13.5 +/- 1.8 vs. 15.0 +/- 1.9 mmol . 9 hr(-1) . L(-1); p = .004). Serum CRP concentrations did not differ between trials or over time. This study demonstrates that accumulating short bouts of running reduces postprandial plasma TAG concentrations (a marker for cardiovascular disease risk) but does not alter serum CRP concentrations.

    PubMed

  • AEROBIC EXERCISE AND POSTPRANDIAL LIPEMIA: ISSUES ON VOLUME AND FREQUENCY OF EXERCISE

    Masashi Miyashita, David Stensel

    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE   41 ( 4 ) 965 - 965  2009年04月

    DOI PubMed

    Scopus

    2
    被引用数
    (Scopus)
  • 若年健常男性における短期間のビタミンEサプリメント摂取は長時間の反復運動後の炎症および筋損傷マーカーに影響を及ぼさない

    宮下 政司, 朴 鐘薫

    体力科學   57 ( 3 ) 383 - 391  2008年06月  [査読有り]

     概要を見る

    After a single bout of prolonged strenuous exercise, inflammatory and muscle damage markers increase. The present study investigated whether vitamin E supplementation can attenuate inflammatory (C-reactive protein (CRP) and interleukin-6 (IL〜6)) and muscle damage (creatine kinase (CK) and lactate dehydrogenese (LDH)) markers after prolonged repeated bouts of cycling in healthy young men. Eight young males (aged 21-30 y) were received both vitamin E supplement (300 mg/day) and placebo (control) for 14 days separated by at least an interval of 1 month in a randomised, counterbalanced design. On day 12 of both trials, subjects cycled at 80% of maximal heart rate in two, 90-min bouts (150min rest between each). Blood samples were collected on days 1 (baseline), 12 (pre- and post-exercise 1 and pre- and post-exercise 2), 13, 14, and 15. After 14 days of supplementation, serum α-tocopherol concentrations increased in the vitamin E trial (P<0.0005) but not the placebo trial. Serum CRP concentrations did not differ between trials and did not significantly change over the observation period in both trials. Serum IL-6, CK, and LDH concentrations increased (P&le;0.024) in response to repeated bouts of exercise in both trials but did not differ between trials. The study demonstrates that short-term vitamin E supplementation appears to have no effect on attenuating markers of inflammatory and muscle damage in response to repeated bouts of prolonged exercise in healthy young men.

    CiNii

  • Changes in substrate oxidation persist overnight after a marathon race

    Kaito Iwayama, Masashi Miyashita, Kumpei Tokuyama

    JAPANESE JOURNAL OF PHYSICAL FITNESS AND SPORTS MEDICINE   57 ( 1 ) 163 - 168  2008年02月  [査読有り]

    CiNii

  • Changes in substrate oxidation persist overnight after a marathon race

    Kaito Iwayama, Masashi Miyashita, Kumpei Tokuyama

    JAPANESE JOURNAL OF PHYSICAL FITNESS AND SPORTS MEDICINE   57 ( 1 ) 163 - 168  2008年02月  [査読有り]

  • Different patterns of physical activity are equally effective in reducing postprandial triacylglycerol concentrations in young men

    Miyashita, Masashi, Burns, Stephen F, Stensel, David J

    Japanese Journal of Physical Fitness and Sports Medicine   57 ( 1 )  2008年02月  [査読有り]

     概要を見る

    Background: Public health guidelines on physical activity recommend that adults accumulate 30 minutes of moderate intensity activity on most, preferably all, days of week (Department of Health UK, 2004; Pate et al., 1995). The guidelines also included the caveat that the minimum duration of any one bout should be 10 minutes. However, if total energy expenditure is the most important factor for health benefits, as is suspected (Pate et al., 1995), then the duration of exercise should not matter provided that sufficient energy is expended. The acute effect of a total of 30 minutes of accumulated exercise in bouts shorter than 10 minutes per session throughout the day on postprandial triacylglycerol concentrations has not been determined. Here we report the findings from two studies which compare the effects of accumulating ten, three-minute bouts of exercise versus one, 30-minute bout of exercise on postprandial triacylglycerol concentrations. Methods: Ten male subjects, aged 23±1 years (mean±SE) (running study) and 15 male subjects, aged 25±1 years (walking study) completed three, 2-day trials at least one week apart in a randomised, repeated measures design. On day 1, subjects rested (no exercise) or ran at 70% of maximum oxygen uptake (running study)/walked briskly at a self-selected pace (walking study) in either ten, three-minute bouts (i.e. 09:30 AM to 15:30 PM) with 30 minutes rest between each, or one continuous 30-minute bout (i.e. 15:00 to 15:30 PM). On day 2, subjects rested and consumed test meals (0.69 g fat, 0.95 g carbohydrate, 0.31 g protein, and 46 kJ/kg body mass) for breakfast and lunch. Venous blood samples were collected in the fasted state and for 7 h postprandially on day 2. Results: In both the running and the walking studies postprandial plasma triacylglycerol concentrations were significantly (two-way ANOVA, P<0.05) lower throughout day 2 on the accumulated and continuous exercise trials compared with the control trials: time-averaged postprandial concentrations 1.86 ± 0.32 versus 1.79 ± 0.33 versus 2.37 ± 0.45 mmol/L respectively for the running study and 1.33 ± 0.09 versus 1.36 ± 0.11 versus 1.62 ± 0.15 mmol/L respectively for the walking study. There were no significant differences between the accumulated and continuous exercise trials. Conclusion: These data demonstrate that: 1) accumulated physical activity is at least as effective as continuous physical activity in reducing postprandial plasma triacylglycerol concentrations in young men and 2) both walking and running are effective in reducing postprandial plasma triacylglycerol concentrations in young men.

  • Moderate exercise reduces serum triacylglycerol concentrations but does not affect pre-heparin lipoprotein lipase concentrations after a moderate-fat meal in young men

    Masashi Miyashita, Kumpei Tokuyama

    British Journal of Nutrition   99 ( 5 ) 1076 - 1082  2008年

     概要を見る

    Aerobic exercise has been shown to lower postprandial TAG concentrations after a meal(s) of high-fat content. This study examined the effects of moderate-intensity cycling on postprandial TAG concentrations and pre-heparin lipoprotein lipase concentrations after subjects consumed a meal of moderate-fat content (45 % of total energy). Twelve male subjects, aged 24 (sem 1) years, completed two 2 d trials (exercise and control) at least 1 week apart in a randomised, repeated measures design. On day 1, subjects either cycled for 30 min at 65 % of maximum heart rate in the afternoon or rested (no exercise). On day 2 of both trials, after an overnight stay with an 11 h fast, subjects consumed a test meal of moderate-fat content (0.61 g fat, 1.34 g carbohydrate, 0.37 g protein and 51 kJ energy/kg body mass) for breakfast. Blood samples were collected at baseline (before the exercise or at an equivalent time-point during the control trial on day 1), in the fasted state (0 h) and at 2, 4 and 6 h postprandially on day 2. The total and incremental areas under the serum TAG concentration v. time curve were 30 % (P = 0.039) and 33 % (P = 0.012) lower on the exercise trial compared with the control trial, respectively. Serum pre-heparin lipoprotein lipase concentrations did not differ between the exercise and control trials. These findings demonstrate that 30 min of moderate-intensity cycling performed the day before a meal of moderate-fat content is effective at lowering postprandial serum TAG concentrations but does not affect serum pre-heparin lipoprotein lipase concentrations in young men. © The Authors 2007.

    DOI PubMed

    Scopus

    21
    被引用数
    (Scopus)
  • Accumulating short bouts of brisk walking reduces postprandial plasma triacylglycerol concentrations and resting blood pressure in healthy young men.

    Miyashita Masashi, Burns Stephen F, Stensel David J

    The American journal of clinical nutrition   88 ( 5 )  2008年

     概要を見る

    BACKGROUND:Physical activity recommendations promote the accumulation of aerobic activity in bouts of &gt;or=10 min. It is important to determine whether shorter bouts of activity can influence health.;OBJECTIVE:We compared the effects of accumulating ten 3-min bouts of brisk walking with those of one 30-min bout of brisk walking on postprandial plasma triacylglycerol concentrations and resting blood pressure.;DESIGN:Fifteen healthy young men completed three 2-d trials &gt;or=1 wk apart in a randomized, repeated-measures design. On day 1, subjects rested (no exercise) or walked briskly in either ten 3-min bouts (30 min rest between each) or one 30-min bout (gross energy expenditure: 1.10 MJ/30 min). On day 2, subjects rested and consumed high-fat test meals for breakfast and lunch.;RESULTS:On day 2 area under the plasma triacylglycerol concentration over time curve was 16% lower on the accumulated and continuous brisk walking trials than on the control trial (x +/- SEM: 9.98 +/- 0.67 compared with 9.99 +/- 0.76 compared with 11.90 +/- 1.02 mmol x 7h/L, respectively; P = 0.005, one-factor ANOVA). Resting systolic blood pressure was 6-7% lower throughout day 2 on the accumulated and contin

    PubMed

  • Effects of continuous versus accumulated activity patterns on postprandial triacylglycerol concentrations in obese men.

    Miyashita M

    International journal of obesity (2005)   32 ( 8 )  2008年

     概要を見る

    OBJECTIVE:There is limited information regarding the effects of short (<10 min) bouts of activity on postprandial lipaemia and no studies are available regarding the effects of short bouts of activity on postprandial lipaemia in obese men. The objective of this study was to compare the effects of accumulating ten, 3-min bouts of exercise versus one 30 min bout of exercise on postprandial serum triacylglycerol (TAG) concentrations in obese men.;DESIGN:Each subject completed three 2-day trials at least 1 week apart in a randomized, repeated-measures design. On day 1, subjects rested (no exercise) or cycled at 60% of maximum heart rate in either ten, 3-min bouts (30 min rest between each), or one continuous 30-min bout. On day 2 of each trial, after an overnight fast, the subjects consumed a standardized test meal for breakfast. Venous blood samples were obtained in the fasted state (0 h), and 2, 4 and 6 h postprandially on day 2.;SUBJECTS:Eight sedentary men (age: 27+/-2 years) with body mass index between 25 and 37 kg/m(2).;MEASUREMENTS:Postprandial TAG, non-esterified fatty acids, 3-hydroxybutyrate, insulin and glucose were determined.;RESULTS:Total area under the postprandial serum TAG concentrations versus time curve was 18% (P=0.042) and 15% (P=0.032) lower throughout day 2 of both the accumulated exercise trial and the continuous exercise trial, respectively, compared with the control trial with little difference between exercise trials.;CONCLUSION:At 30 min of moderate cycling (0.87 MJ per 30 min) accumulated in short bouts is equally effective in reducing postprandial serum TAG concentrations as one continuous 30 min bout of cycling in obese men.

    DOI PubMed

    Scopus

    37
    被引用数
    (Scopus)
  • Multiple bouts of resistance exercise and postprandial triacylglycerol and serum C-reactive-protein concentrations

    Stephen F. Burns, Masashi Miyashita, Chihoko Ueda, David J. Stensel

    INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM   17 ( 6 ) 556 - 573  2007年12月  [査読有り]

     概要を見る

    The present study examined how multiple bouts of resistance exercise, performed over 1 d, influence 2 risk factors-postprandial triacylglycerol (TAG) and serum C-reactive-protein (CRP) concentrations-associated with coronary heart disease. Twenty-four men age 23.5 (SD 3.4) y completed two 2-d trials, exercise and control, at least 1 wk apart in a counterbalanced randomized design. On day 1 of the exercise trials participants completed 20 sets of 15 repetitions of 5 different resistance exercises divided into five 45-min bouts of exercise-100 sets and 1500 repetitions in total for all exercises. Exercises were performed at 30-40% of 1-repetition maximum. Blood samples were taken before and after exercise. On day 1 of the control trial participants were inactive, with blood samples taken at time points corresponding to the exercise trial. On day 2 of both trials participants consumed a test meal (0.89 g fat, 1.23 g carbohydrate, 0.4 g protein, 60 kJ per kg body mass). Blood samples were obtained fasted and for 6 h postprandially. Total area under the postprandial TAG concentration versus time curve was 12% lower in the exercise than in the control trial (8.76 [3.54] vs. 9.94 [4.31] mmol.L-1.6 h, respectively; P = 0.037). Serum CRP concentrations did not change over the 2 d in the control trial but increased in the exercise trial: trial x time interaction (P = 0.028). Multiple bouts of resistance exercise reduce postprandial TAG concentrations but increase serum CRP concentrations. The extent to which these findings are clinically relevant requires further study.

    PubMed

  • 就寝直前の夕食が睡眠時のエネルギー代謝に及ぼす影響

    中村 和照, 宮下 政司, 緒形 ひとみ, 長坂 昌一郎, 徳山 薫平

    肥満研究 : 日本肥満学会誌 = Journal of Japan Society for the Study of Obesity   13 ( 3 ) 250 - 255  2007年12月

    CiNii

  • A single session of treadmill running has no effect on plasma total ghrelin concentrations.

    Burns Stephen F, Broom David R, Miyashita Masashi, Mundy Claire, Stensel David J

    Journal of sports sciences   25 ( 6 )  2007年

     概要を見る

    :Ghrelin is a hormone that stimulates hunger. Intense exercise has been shown to temporarily suppress hunger after exercise. In the present study, we investigated whether post-exercise hunger suppression is mediated by reduced plasma total ghrelin concentrations. Nine men and nine women participated in the study. Their mean physical characteristics were as follows: age 24.8 (s(x) = 0.9) years, body mass index 22.9 (s(x) = 0.6) kg x m(-2), maximal oxygen uptake (VO(2max)) 57.7 (s(x) = 2.2) ml x kg(-1) x min(-1). The participants completed two 3-h trials (exercise and control) on separate days in a randomized balanced design after overnight fasts. The exercise trial involved a 1-h treadmill run at 73.5% of VO(2max) followed by 2 h of rest. The control trial consisted of 3 h of rest. Blood samples were collected at 0, 0.5, 1, 1.5, 2, and 3 h. Total ghrelin concentrations were determined from plasma. Hunger was assessed following blood sampling using a 15-point scale. The data were analysed using repeated-measures analysis of variance. Hunger scores were lower in the exercise trial than in the control trial (trial, P = 0.009; time, P &lt; 0.001; trial x time, P &lt; 0.001). Plasma total ghre

    PubMed

  • Exercise-induced suppression of acylated ghrelin in humans.

    Broom D R, Stensel D J, Bishop N C, Burns S F, Miyashita M

    Journal of applied physiology (Bethesda, Md. : 1985)   102 ( 6 )  2007年

     概要を見る

    :Ghrelin is an orexigenic hormone secreted from endocrine cells in the stomach and other tissues. Acylation of ghrelin is essential for appetite regulation. Vigorous exercise induces appetite suppression, but this does not appear to be related to suppressed concentrations of total ghrelin. This study examined the effect of exercise and feeding on plasma acylated ghrelin and appetite. Nine male subjects aged 19-25 yr participated in two, 9-h trials (exercise and control) in a random crossover design. Trials began at 0800 in the morning after an overnight fast. In the exercise trial, subjects ran for 60 min at 72% of maximum oxygen uptake between 0800 and 0900. After this, they rested for 8 h and consumed a test meal at 1100. In the control trial, subjects rested for 9 h and consumed a test meal at 1100. Area under the curve values for plasma acylated ghrelin concentration (assessed from venous blood samples) were lower over the first 3 h and the full 9 h of the exercise trial compared with the control trial: 317+/-135 vs. 510+/-186 pg.ml(-1).3 h and 917+/-342 vs. 1,401+/-521 pg.ml(-1).9 h (means+/-SE) respectively (P&lt;0.05). Area under the curve values for hunger (assessed using a vi

    PubMed

  • Increased postprandial triacylglycerol concentrations following resistance exercise.

    Burns Stephen F, Broom David R, Miyashita Masashi, Ueda Chihoko, Stensel David J

    Medicine and science in sports and exercise   38 ( 3 )  2006年

     概要を見る

    PURPOSE:There is conflicting evidence whether a single bout of resistance exercise performed the day before a test meal can lower postprandial triacylglycerol (TAG) concentrations. The present study examined the effect of a single session of resistance exercise, performed the same day as a test meal, on postprandial TAG concentrations in resistance-trained males.;METHODS:Ten healthy males aged 25 (SD 2.6) yr performed two trials at least 1 wk apart in a counterbalanced, randomized design. In each trial, participants consumed a test meal (0.89 g of fat, 1.23 g of carbohydrate, 0.4 g of protein, 60 kJ.kg body mass). Before one meal, participants performed a 90-min bout of resistance exercise. Before the other meal, participants were inactive (control trial). Resistance exercise was performed using free weights and included three sets of 12 repetitions of each of 10 exercises. Sets were performed at 80% of 12-repetition maximum with a 3-min work and rest interval. Venous blood samples were obtained in the fasted state and for 5 h postprandially.;RESULTS:Total area under the plasma TAG concentration versus time curve was higher (Student&#039;s t-test P = 0.008) on the exercise than control

    PubMed

  • Exercise and postprandial lipemia: effect of continuous compared with intermittent activity patterns.

    Miyashita Masashi, Burns Stephen F, Stensel David J

    The American journal of clinical nutrition   83 ( 1 )  2006年  [査読有り]

     概要を見る

    BACKGROUND:Guidelines state that accumulated physical activity is beneficial for health, but a minimum duration of 10 min per activity bout is recommended. Limited information regarding the effects of short (< 10 min) bouts of activity on health is available, and no studies of the effects of such short bouts of activity on postprandial lipemia have been conducted.;OBJECTIVE:The objective was to compare the effects of accumulating ten 3-min bouts of exercise with those of one 30-min bout of exercise on postprandial plasma triacylglycerol concentrations.;DESIGN:Ten men aged 21-32 y completed three 2-d trials > or = 1 wk apart in a randomized repeated-measures design. On day 1, the subjects rested (no exercise) or ran at 70% of maximum oxygen uptake in either ten 3-min bouts (30 min rest between each) or one continuous 30-min bout. On day 2, the subjects rested and consumed test meals (0.69 g fat, 0.95 g carbohydrate, 0.31 g protein, and 46 kJ/kg body mass) for breakfast and lunch. Venous blood samples were obtained in the fasted state and for 7 h postprandially on day 2.;RESULTS:Postprandial plasma triacylglycerol concentrations were lower throughout day 2 of both the accumulation exercise trial and the continuous exercise trial than during the control trial (main effect of trial: P < 0.001, 2-factor analysis of variance).;CONCLUSIONS:Accumulating multiple short bouts of exercise throughout the day effectively reduce postprandial plasma triacylglycerol concentrations to an extent similar to that of a single 30-min session of exercise in healthy young men.

    PubMed

▼全件表示

書籍等出版物

  • Physical activity in the prevention of atherosclerosis: focus on oxidative stress and oxidised low-density lipoprotein(分担執筆)

    Springer Japan, Tokyo  2015年04月

  • メディカルフィットネス研究会(編集):メディカルフィットネスQ&A.(分担執筆)

    2014年01月 ISBN: 9784789468602

  • 公益社団法人日本プロボウリング協会(監修):健幸華齢ボウリングQ&A.(分担執筆)

    株式会社社会保険研究所(東京)  2014年01月

  • エクササイズ科学:健康体力つくりと疾病・介護予防のための基礎と実践(田中喜代次・田端泉 編)(分担執筆)

    文光堂(東京)  2012年02月 ISBN: 9784830651779

Misc

  • High-Intensity Interval Exercise and Postprandial Triacylglycerol

    Stephen F. Burns, Masashi Miyashita, David J. Stensel

    SPORTS MEDICINE   45 ( 7 ) 957 - 968  2015年07月

    書評論文,書評,文献紹介等  

     概要を見る

    This review examined if high-intensity interval exercise (HIIE) reduces postprandial triacylglycerol (TAG) levels. Fifteen studies were identified, in which the effect of interval exercise conducted at an intensity of &gt;65 % of maximal oxygen uptake was evaluated on postprandial TAG levels. Analysis was divided between studies that included supramaximal exercise and those that included submaximal interval exercise. Ten studies examined the effect of a single session of low-volume HIIE including supramaximal sprints on postprandial TAG. Seven of these studies noted reductions in the postprandial total TAG area under the curve the morning after exercise of between similar to 10 and 21 % compared with rest, but three investigations found no significant difference in TAG levels. Variations in the HIIE protocol used, inter-individual variation or insufficient time post-exercise for an increase in lipoprotein lipase activity are proposed reasons for the divergent results among studies. Five studies examined the effect of high-volume submaximal interval exercise on postprandial TAG. Four of these studies were characterised by high exercise energy expenditure and effectively attenuated total postprandial TAG levels by similar to 15-30 %, but one study with a lower energy expenditure found no effect on TAG. The evidence suggests that supramaximal HIIE can induce large reductions in postprandial TAG levels but findings are inconsistent. Submaximal interval exercise offers no TAG metabolic or time advantage over continuous aerobic exercise but could be appealing in nature to some individuals. Future research should examine if submaximal interval exercise can reduce TAG levels in line with more realistic and achievable exercise durations of 30 min per day.

    DOI

  • 一過性のガム咀嚼・高強度運動が食欲関連ホルモン及びエネルギー摂取量に及ぼす影響

    柏原杏子, 城所哲宏, 柳岡拓磨, 宮下政司

    日本咀嚼学会雑誌   印刷中   -  2015年05月

  • Effects of breaking sitting by standing and acute exercise on postprandial oxidative stress

    Takahashi, Masaki, Miyashita, Masashi, Park, Jong Hwan, Sakamoto, Shizuo, Suzuki, Katsuhiko

    Asian Journal of Sports Medicine   6 ( 3 ) -  2015年01月  [査読有り]

     概要を見る

    © 2015, Sports Medicine Research Center.Background: Sedentary behavior, which includes sitting and TV viewing, has been identified as an independent risk factor for type 2 diabetes and cardiovascular disease. Breaking sedentary behavior improves metabolic health such as postprandial glycaemia and insulinemia. However, the mechanisms underlying this effect are unclear. Objectives: Here, we examined whether breaking sitting by standing and acute exercise reduces postprandial oxidative stress. Patient and Methods: Fifteen participants performed 3 trials (sitting, standing, and exercise), each lasting 2 days, in a randomised order. On day one of sitting trial, participants sat in a chair. For the standing trial, the participants stood 6 times, for a 45-minute period each time. For the exercise trial, the participants walked or ran at approximately 60% of age-predicted maximum heart rate for 30 minutes. On day two of each trial, participants rested and consumed the standardised breakfast and lunch. Blood samples were collected in the morning and afternoon on day one, and fasting and at 2, 4, and 6 hours postprandially on day two. Results: The concentrations of serum derivatives of reactive oxygen metabolites (d-ROMs) measured at 4 hours (P = 0.064) and 6 hours (P = 0.071) tended to be higher than that in the fasting state in the sitting trial, but not standing and exercise trial (two-factor analysis of variance (ANOVA), trial × time interaction, P = 0.006). Conclusions: Our results indicate the importance of reducing sitting time for improving postprandial oxidative stress status.

    DOI

  • 異なるアクティブリカバリー方法がサッカー審判員の血中乳酸濃度に及ぼす影響

    柳岡拓磨, 宮下政司, 瀧井敏郎

    トレーニング科学   印刷中   -  2015年

  • Comment on Bazzano

    Burns SF, Miyashita M

    Annals of Internal Medicine   162   391 -  2015年

  • サッカーの試合における、主審、副審の活動形態と運動強度の違い

    長谷川雅, 宮下政司

        -  2015年

  • Acute ingestion of catechin-rich green tea improves postprandial glucose status and increases serum thioredoxin concentrations in postmenopausal women.

    Takahashi Masaki, Miyashita Masashi, Suzuki Katsuhiko, Bae Seong-Ryu, Kim Hyeon-Ki, Wakisaka Takuya, Matsui Yuji, Takeshita Masao, Yasunaga Koichi

    The British journal of nutrition   112 ( 9 ) -  2014年

     概要を見る

    :Elevated postprandial hyperglycaemia and oxidative stress increase the risks of type 2 diabetes and CVD. Green tea catechin possesses antidiabetic properties and antioxidant capacity. In the present study, we examined the acute and continuous effects of ingestion of catechin-rich green tea on postprandial hyperglycaemia and oxidative stress in healthy postmenopausal women. Participants were randomly assigned into the placebo (P, n 11) or green tea (GT, n 11) group. The GT group consumed a catechin-rich green tea (catechins 615 mg/350 ml) beverage per d for 4 weeks. The P group consumed a placebo (catechins 92 mg/350 ml) beverage per d for 4 weeks. At baseline and after 4 weeks, participants of each group consumed their designated beverages with breakfast and consumed lunch 3 h after breakfast. Venous blood samples were collected in the fasted state (0 h) and at 2, 4 and 6 h after breakfast. Postprandial glucose concentrations were 3 % lower in the GT group than in the P group (three-factor ANOVA, group × time interaction, P< 0·05). Serum concentrations of the derivatives of reactive oxygen metabolites increased after meals (P< 0·05), but no effect of catechin-rich green tea intake was observed. Conversely, serum postprandial thioredoxin concentrations were 5 % higher in the GT group than in the P group (three-factor ANOVA, group × time interaction, P< 0·05). These findings indicate that an acute ingestion of catechin-rich green tea has beneficial effects on postprandial glucose and redox homeostasis in postmenopausal women.

    DOI

  • Low-volume physical activity programme improves cardiovascular disease risk markers in older adults

    Park J-H, Miyashita M, Takahashi M, Kawanishi N, Hayashida H, Kim H-S, Suzuki K, Nakamura Y

    Journal of Sports Science and Medicine   13 ( 3 ) 624 - 631  2014年

  • Increased participation in weekend physical activity reduces postprandial lipemia in postmenopausal women.

    Miyashita M, Takahashi M, Burns S

    International journal of sports medicine   35 ( 13 ) -  2014年

     概要を見る

    :This study examined the acute effect of increased participation in weekend physical activity on postprandial lipemia in postmenopausal women. Ten postmenopausal women, aged 63±4 years (mean±SD), completed 2 trials in a random order: 1) control trial and 2) active trial. In the control trial, participants maintained their usual weekend lifestyle. In the active trial, participants increased their weekend activities above their usual lifestyle levels, freely deciding the duration and intensity of their chosen activities. On Monday of each trial, participants rested and consumed a standardised breakfast and lunch. Capillary blood samples were collected in the fasted state (0 h) and at 2, 4 and 6 h after eating. In the active trial, participants increased their moderate to vigorous weekend physical activity by 16 min (mean±SD: 12.3±6.7 min vs. 27.9±11.9 min, P=0.009). Area under the capillary triacylglycerol concentration vs. time curve was 13% lower in the active trial than control trial (8.8±3.8 vs. 10.1±3.9 mmol/L∙6 h, P=0.024). These findings demonstrate that small increases in moderate to vigorous physical activity under a real-life setting lowers postprandial lipemia in postmenopausal women.

    DOI

  • 脂質異常症の予防のための運動・生活活動を科学する

    宮下政司

    ランニング学研究   25 ( 2 ) 9 - 14  2014年

  • Effects of curcumin supplement on exercise-induced oxidative stress: a randomized, double-blind, placebo-controlled trial

    Takahashi M, Suzuki K, Kim H-K, Otsuka Y, Imaizumi A, Miyashita M, Sakamoto S

    International Journal of Sports Medicine   35 ( 6 ) 469 - 475  2014年

    DOI

  • Associations between health-related physical fitness and obesity in Taiwanese youth

    Yung Liao, Shao-Hsi Chang, Masashi Miyashita, David Stensel, Jui-Fu Chen, Liang-Tsai Wen, Yoshio Nakamura

    JOURNAL OF SPORTS SCIENCES   31 ( 16 ) 1797 - 1804  2013年12月

     概要を見る

    This study examined associations between four health-related physical fitness measures and obesity in Taiwanese youth aged 10-18 years. Data from 13,500 school-aged youth were randomly selected from the School Physical Fitness Database of Taiwan by sex and age. Variables examined were height, body mass and performance on modified sit-and-reach (flexibility), bent-leg sit-up (abdominal muscular strength/endurance), standing long jump (lower body explosive strength) and distance run/walk (cardiorespiratory endurance). Adjusted logistic regression analyses were performed. Increased odds of being obese with decreased fitness levels were observed for lower body explosive strength and cardiorespiratory endurance in both sexes. The highest odds of being obese was found in the least fit quintile of cardiorespiratory endurance compared with the most fit quintile both in boys (Odds ratio, OR=10.44; 95% confidence interval (CI), 7.94-13.73) and girls (OR=5.40; 95% CI, 3.90-7.47). These findings suggest that in addition to cardiorespiratory fitness, lower body explosive strength is also associated with childhood and adolescent obesity.

    DOI

  • The association between physical activity and sex-specific oxidative stress in older adults

    Takahashi, Masaki, Miyashita, Masashi, Park, Jong Hwan, Kim, Hyun Shik, Nakamura, Yoshio, Sakamoto, Shizuo, Suzuki, Katsuhiko

    Journal of Sports Science and Medicine   12 ( 3 ) 571 - 578  2013年09月

     概要を見る

    Oxidative stress increases with advancing age and is a mediator of several diseases including cancer, cardiovascular disease, and diabetes. Moreover, postmenopausal women have a lower estrogen concentration, which is associated with elevated oxidative stress. However, there is no definitive evidence regarding the relationship between daily physical activity and oxidative stress status in older adults, including postmenopausal women. Twenty- nine adults (age, 70.1 ± 1.0 years, mean ± SE; 12 women and 17 men) were examined in this cross-sectional study. Prior to blood collection, the participants were asked to wear a uniaxial accelerometer for 4 consecutive weeks to determine their level of physical activity. After a 48-h period of physical activity avoidance and a 10-h overnight fast, venous blood samples were obtained from each participant. Fasting plasma derivatives of reactive oxygen metabolites (d-ROMs) and malondialdehyde (MDA) concentrations of oxidative stress markers were negatively correlated with the amount of physical activity in women (d-ROMs; r = -0.708, p = 0.002) (MDA; r = -0.549, p = 0.028), but not in men. Fasting plasma biological antioxidant potential of antioxidant capacity marker was positively correlated with the amount of physical activity in women (BAP; r = 0.657, p = 0.006) (GSH; r = 0.549, p = 0.028), but not in men. Moreover, superoxide dismutase activity of antioxidant capacity marker was positively correlated with the amount of physical activity in men (r = 0.627, p = 0.039), but not in women. There were no associations between physical activity and other oxidative stress markers (reduced and oxidized glutathione, glutathione peroxidise, thioredoxin). These findings suggest that regular physical activity may have a protective effect against oxidative stress by increasing total antioxidant capacity, especially in postmenopausal women. © Journal of Sports Science and Medicine.

  • Effects of different modes of exercise on appetite and appetite-regulating hormones

    Hiroshi Kawano, Mayuko Mineta, Meiko Asaka, Masashi Miyashita, Shigeharu Numao, Yuko Gando, Takafumi Ando, Shizuo Sakamoto, Mitsuru Higuchi

    Appetite   66 ( 7 ) 26 - 33  2013年07月

     概要を見る

    The present study determined the changes in appetite and appetite-regulating gut hormones during and following bouts of both rope skipping exercise (weight-bearing) and bicycle ergometer exercise (non-weight-bearing). After a 12-h fast, 15 young men (mean ± SD, age 24.4 ± 1.7. yrs, maximal oxygen uptake 47.0 ± 6.5. mL/kg/min) participated in three 160. min trials: (1) rope skipping exercise (295 ± 40. kcal, 3 sets × 10. min with 5-min interval, then rested for 120. min)
    (2) bicycle ergometer exercise (288 ± 36. kcal, 3 sets × 10. min with 5-min interval, then rested for 120. min)
    (3) control (rested for 160. min). Ratings of perceived hunger and acylated ghrelin were suppressed and total peptide YY (PYY) were increased during and immediately after exercise in both exercise trials, but glucagon liked peptide-1 was not changed. Furthermore, suppressed hunger during rope skipping exercise was greater than that during bicycle ergometer exercise, but there were no differences in acylated ghrelin and total PYY. These results indicate that weight-bearing exercise has a greater exercise-induced appetite suppressive effect compared with non-weight-bearing exercise, and both forms of exercise lowered acylated ghrelin and increased total PYY, but the changes did not differ significantly between exercise modes. © 2013 Elsevier Ltd.

    DOI PubMed

  • Effects of intermittent physical activity on fat utilization over a whole day.

    Takafumi Ando, Chiyoko Usui, Kazunori Ohkawara, Rieko Miyake, Masashi Miyashita, Jonghoon Park, Osamu Ezaki, Mitsuru Higuchi, Shigeho Tanaka

    Medicine and science in sports and exercise   45 ( 7 ) 1410 - 8  2013年07月  [査読有り]   [ 国際誌 ]

     概要を見る

    PURPOSE: We examined whether continuous and intermittent physical activity (PA) differentially influence fat utilization. METHODS: This was a randomized crossover study. Nine healthy young male participants performed two 39-h (two nights, three days) PA sessions (continuous and intermittent exercise) in a respiratory chamber to measure energy expenditure (EE) and substrate oxidation. Participants used a stationary cycling ergometer continuously for 40 min and then 45 min in the continuous PA trial and for 5 min every 30 min 17 times in the intermittent PA trial. They consumed high-carbohydrate meals corresponding to predicted daily total EE for 3 d before entering the respiratory chamber and four high-fat meals corresponding to predicted total EE in the chamber. RESULTS: Twenty-three-hour RER adjusted for sleeping RER on the preceding day was significantly lower in the intermittent PA trial than that in the continuous PA trial (P = 0.021). Twenty-three-hour RER adjusted for sleeping RER on the preceding day was correlated with accumulated consecutive minutes of METs ≤ 1.5 (3 min or more, r = 0.477; 5 min or more, r = 0.510; 10 min or more, r = 0.605). CONCLUSIONS: The intermittent PA trial induced greater fat utilization than the continuous PA trial. The present study, therefore, suggests that intermittent PA has a beneficial effect on 24-h fat oxidation after consumption of a high-fat meal, which may help prevent weight gain over time.

    DOI PubMed

  • Effects of low-volume walking programme and vitamin E supplementation on oxidative damage and health-related variables in healthy older adults

    Jong-Hwan Park, Masashi Miyashita, Masaki Takahashi, Noriaki Kawanishi, Seong-Ryu Bae, Hyun-Shik Kim, Katsuhiko Suzuki, Yoshio Nakamura

    NUTRITION & METABOLISM   10 ( 1 ) 38 -  2013年05月  [査読有り]

     概要を見る

    Background: Both exercise and vitamin E supplementation have been shown to reduce oxidative stress and cardiovascular disease risk in older adults, and when combined there is evidence suggesting that they act synergistically. The currently recommended amount of exercise for older adults is 150 min/week of moderate-intensity exercise; however, the minimum amount of exercise necessary to achieve health benefits is not known. The purpose of this study was to investigate the effects of 12 weeks of participation in a low-volume walking exercise programme (i.e. 90 min/week) combined with daily vitamin E supplementation on thiobarbituric acid reactive substances (TBARS) and oxidised low-density lipoprotein (LDL) concentrations in older adults.
    Methods: The participants were recruited from the following four groups separately: 1) control (CG, n = 14), 2) vitamin E supplementation (SG, n = 10), 3) walking (WG, n = 7), or 4) walking + supplementation (WSG, n = 7). In the CG, participants were advised to maintain their normal lifestyle during the study. Participants in both the SG and WSG received 450 IU (300 mg) /day of a-tocopherol for 12 weeks. The exercise programme for the WG and WSG consisted of two 30-60 minute sessions weekly for 12 weeks (average walking time was 44.5 +/- 1.6 min/session). Blood samples were collected at baseline and at 12 weeks.
    Results: Delta plasma oxidised LDL concentrations did not differ among four groups (One-factor ANOVA, P = 0.116). However, negative delta plasma TBARS, a marker of oxidative damage, concentrations were observed in the WG, WSG and SG relative to the CG at the end of the study period (One-factor ANOVA, P = 0.001; post hoc tests; CG compared with WG, WSG and SG, P = 0.005; P = 0.021; P = 0.024, respectively).
    Conclusion: These findings suggest that a low-volume of physical activity and/or vitamin E supplementation may be an effective intervention strategy for reducing TBARS concentrations of older adults.
    Trial registration: UMIN000008304

    DOI

  • Effect of one night of sleep deprivation on maximal fat oxidation during graded exercise

    Konishi Masayuki, Takahashi Masaki, Naoya@Endo, NUMAO Shigeharu, TAKAGI Shun, MIYASHITA Masashi, MIDORIKAWA Taishi, SUZUKI Katsuhiko, SAKAMOTO Shizuo

    The journal of physical fitness and sports medicine : JPFSM   2 ( 1 ) 121 - 126  2013年03月

     概要を見る

    The aim of this study was to investigate the effects of one night of sleep deprivation on maximal fat oxidation during a graded exercise test. Ten healthy young males underwent two 2-day control and sleep deprivation trials. Participants were allowed normal sleep from 2300 to 0700 for the control trial, whereas they were required to stay awake for 34 h during the sleep deprivation trial. At 1700 on day 2, participants performed a graded exercise test to exhaustion on a treadmill; this allowed us to determine maximal oxygen uptake and maximal fat oxidation. Before and immediately after the graded exercise test, blood samples were collected in order to measure glucose, insulin, free fatty acid, and triglyceride concentrations. Plasma glucose concentrations were significantly higher in the sleep deprivation trial than in the control trial before the graded exercise test. Serum insulin and free fatty acid concentrations were not significantly different between the two trials. Serum triglyceride concentrations were significantly lower in the sleep deprivation trial than in the control trial. The maximal fat oxidation rate, oxygen uptake, and heart rate at maximal fat oxidation intensity, during the graded exercise test, were not significantly different between the two trials. These findings suggest that maximal fat oxidation during graded exercise is unaffected by one night of sleep deprivation.

    DOI CiNii

  • Effects of sleep deprivation on autonomic and endocrine functions throughout the day and on exercise tolerance in the evening

    Masayuki Konishi, Masaki Takahashi, Naoya Endo, Shigeharu Numao, Shun Takagi, Masashi Miyashita, Taishi Midorikawa, Katsuhiko Suzuki, Shizuo Sakamoto

    Journal of Sports Sciences   31 ( 3 ) 248 - 255  2013年

     概要を見る

    The aim of this study was to investigate the effects of sleep deprivation on autonomic and endocrine functions during the day and on exercise tolerance in the evening. Ten healthy young males completed two, 2-day control and sleep deprivation trials. For the control trial, participants were allowed normal sleep from 23:00 to 07:00 h. For the sleep deprivation trial, participants did not sleep for 34 h. Autonomic activity was measured from 19:00 h on day 1 to 16:00 h on day 2 by frequency-domain measures of heart rate variability. Endocrine function was examined by measuring adrenocorticotropic hormone and cortisol from venous blood samples collected on day 2 at 09:00, 13:00, and 17:00 h and immediately after an exercise tolerance testing. Autonomic regulation, particularly parasympathetic regulation estimated from the high-frequency component of heart rate variability analysis, was significantly higher in the sleep deprivation trial than in the control trial in the morning and afternoon of day 2. Plasma adrenocorticotropic hormone concentrations were significantly higher at 09:00 and 13:00 h of day 2 under sleep deprivation. Heart rate during exercise was significantly lower following sleep deprivation. Therefore, the effects of sleep deprivation on autonomic regulation depend on the time of the day. © 2013 Copyright Taylor and Francis Group, LLC.

    DOI PubMed

  • Effects of sleep deprivation on autonomic and endocrine functions throughout the day and on exercise tolerance in the evening

    Masayuki Konishi, Masaki Takahashi, Naoya Endo, Shigeharu Numao, Shun Takagi, Masashi Miyashita, Taishi Midorikawa, Katsuhiko Suzuki, Shizuo Sakamoto

    Journal of Sports Sciences   31 ( 3 ) 248 - 255  2013年

     概要を見る

    The aim of this study was to investigate the effects of sleep deprivation on autonomic and endocrine functions during the day and on exercise tolerance in the evening. Ten healthy young males completed two, 2-day control and sleep deprivation trials. For the control trial, participants were allowed normal sleep from 23:00 to 07:00 h. For the sleep deprivation trial, participants did not sleep for 34 h. Autonomic activity was measured from 19:00 h on day 1 to 16:00 h on day 2 by frequency-domain measures of heart rate variability. Endocrine function was examined by measuring adrenocorticotropic hormone and cortisol from venous blood samples collected on day 2 at 09:00, 13:00, and 17:00 h and immediately after an exercise tolerance testing. Autonomic regulation, particularly parasympathetic regulation estimated from the high-frequency component of heart rate variability analysis, was significantly higher in the sleep deprivation trial than in the control trial in the morning and afternoon of day 2. Plasma adrenocorticotropic hormone concentrations were significantly higher at 09:00 and 13:00 h of day 2 under sleep deprivation. Heart rate during exercise was significantly lower following sleep deprivation. Therefore, the effects of sleep deprivation on autonomic regulation depend on the time of the day. © 2013 Copyright Taylor and Francis Group, LLC.

    DOI PubMed

  • Low-volume exercise training and vitamin E supplementation attenuates oxidative stress in postmenopausal women

    Masaki Takahashi, Masashi Miyashita, Jong-Hwan Park, Noriaki Kawanishi, Seong-Ryu Bae, Yoshio Nakamura, Shizuo Sakamoto, Katsuhiko Suzuki

    Journal of Nutritional Science and Vitaminology   59 ( 5 ) 375 - 383  2013年

     概要を見る

    The purpose of this study was to investigate the effects of low-volume exercise training (90 min/wk) and vitamin E supplementation on oxidative stress markers in postmenopausal women. The participants were non-randomly assigned the following four groups: control (C, n=8), vitamin E (S, n=8), exercise (Ex, n=6), or vitamin E and exercise (S+Ex, n=7). The S and S+Ex groups were instructed to take vitamin E (α-tocopherol, 300 mg/d) capsules for 12 wk. The exercise program of Ex and S+Ex groups consisted of walking for a 30-60 min/session 2 d per week for 12 wk. The serum derivatives of reactive oxygen metabolites concentrations were significantly decreased in the Ex, and S+Ex groups after 12 wk compared with the baseline values (three-factor ANOVA, an interaction between exercise and time, p&lt
    0.05). Conversely, serum biological antioxidant potential concentrations in the S and Ex groups were significantly higher at 12 wk than at the baseline, but not in the S+Ex group (three-factor ANOVA, an interaction between supplementation, exercise and time, p&lt
    0.05). Plasma thioredoxin concentrations in the S, Ex, and S+Ex groups were significantly higher at 12 wk than at the baseline values (three-factor ANOVA, interactions between exercise and time, and between supplementation, exercise and time, p&lt
    0.05). Our findings suggest that low-volume physical activity may improve resting oxidative stress status in postmenopausal women.

    DOI PubMed

  • The influence of vigorous running and cycling exercise on hunger perceptions and plasma acylated ghrelin concentrations in lean young men

    Lucy K. Wasse, Caroline Sunderland, James A. King, Masashi Miyashita, David J. Stensel

    APPLIED PHYSIOLOGY NUTRITION AND METABOLISM-PHYSIOLOGIE APPLIQUEE NUTRITION ET METABOLISME   38 ( 1 ) 1 - 6  2013年01月  [査読有り]

     概要を見る

    Vigorous running suppresses plasma acylated ghrelin concentrations but the limited literature on cycling suggests that acylated ghrelin is unchanged, perhaps because body mass is supported during cycling. It is important from a research and applied perspective to determine whether acylated ghrelin and hunger responses are exercise-mode specific. This study sought to examine this. Eleven recreationally active males fasted overnight and completed three 4-h trials: control, running, and cycling, in a random order. Participants rested throughout the control trial and ran or cycled at 70% of mode-specific maximal oxygen uptake for the first hour during exercise trials, resting thereafter. Hunger was measured every 0.5 h using visual analogue scales. Eight venous blood samples were collected to determine acylated ghrelin concentrations and a standardised meal was consumed at 3 h. Compared with the control trial, acylated ghrelin concentrations were suppressed to a similar extent at 0.5 and 1 h during the running (p &lt; 0.005) and cycling (p &lt; 0.001) trials. Area under the curve values for ghrelin concentration over time were lower during exercise trials versus control (Control: 606 +/- 379; Running: 455 +/- 356; Cycling: 448 +/- 315 pg.mL(-1).4 h(-1); mean +/- SD, p &lt; 0.05). Hunger values did not differ significantly between trials but an interaction effect (p &lt; 0.05) indicated a tendency for hunger to be suppressed during exercise. Thus, at similar relative exercise intensities, plasma acylated ghrelin concentrations are suppressed to a similar extent during running and cycling.

    DOI

  • Low-amount walking training attenuates oxidative stress and neutrophils activation in older adults.

    Takahashi M, Miyashita M, Kawanishi N, Park J-H, Hayashida, H, Kim H-S, Nakamura Y, Sakamoto S, Suzuki K

    European Journal of Applied Physiology   113 ( 5 ) 1117 - 1126  2013年

    DOI

  • サルコペニアに対する低強度運動の有効性

    原田和弘, 宮下政司

    健康支援   15 ( 1 ) 1 - 5  2013年

  • Postprandial Lipaemia: Effects of Sitting, Standing and Walking in Healthy Normolipidaemic Humans

    M. Miyashita, J. -H. Park, M. Takahashi, K. Suzuki, D. Stensel, Y. Nakamura

    INTERNATIONAL JOURNAL OF SPORTS MEDICINE   34 ( 1 ) 21 - 27  2013年01月  [査読有り]

     概要を見る

    Long periods of sedentary behaviour may adversely affect health irrespective of overall physical activity levels. This study compared the effects of sitting, standing and walking on postprandial lipaemia in healthy normolipidaemic Japanese men. 15 participants, aged 26.8 +/- 2.0 years (mean +/- SD), completed 3, 2-day trials in a random order: 1) sitting (control), 2) standing, and 3) walking. On day 1 of the sitting trial, participants rested. On day 1 of the standing trial, participants stood for six, 45-min periods. On day 1 of the walking trial, participants walked briskly for 30 min at approximately 60 % of maximum heart rate. On day 2 of each trial, participants rested and consumed test meals for breakfast and lunch. Venous blood samples were collected in the morning and afternoon on day 1, and in the fasted state (0 h) and at 2, 4 and 6 h postprandially on day 2. On day 2 area under the serum triacylglycerol concentration vs. time curve was 18 % lower on the walking trial than the sitting and standing trials (1-factor ANOVA, P = 0.015). Hence postprandial lipaemia was not reduced after standing but was reduced after low-volume walking compared with sitting in healthy normolipidaemic Japanese men.

    DOI

  • An update on accumulating exercise and postprandial lipaemia: Translating theory into practice

    Masashi Miyashita, Stephen F. Burns, David J. Stensel

    Journal of Preventive Medicine and Public Health   46 ( 1 ) S3 - S11  2013年01月  [査読有り]

    書評論文,書評,文献紹介等  

     概要を見る

    Over the last two decades, significant research attention has been given to the acute effect of a single bout of exercise on postprandial lipaemia. A large body of evidence supports the notion that an acute bout of aerobic exercise can reduce postprandial triacylglycerol (TAG) concentrations. However, this effect is short-lived emphasising the important role of regular physical activity for lowering TAG concentrations through an active lifestyle. In 1995, the concept of accumulating physical activity was introduced in expert recommendations with the advice that activity can be performed in several short bouts throughout the day with a minimum duration of 10 minutes per activity bout. Although the concept of accumulation has been widely publicised, there is still limited scientific evidence to support it but several studies have investigated the effects of accumulated activity on health-related outcomes to support the recommendations in physical activity guidelines. One area, which is the focus of this review, is the effect of accumulating exercise on postprandial lipaemia. We propose that accumulating exercise will provide additional physical activity options for lowering postprandial TAG concentrations relevant to individuals with limited time or exercise capacity to engage in more structured forms of exercise, or longer bouts of physical activity. The benefits of accumulated physical activity might translate to a reduced risk of cardiovascular disease in the long-term. Copyright © 2013 The Korean Society for Preventive Medicine.

    DOI PubMed

  • Beneficial effects of combined olive oil ingestion and acute exercise on postprandial TAG concentrations in healthy young women

    Chihoko Sasahara, Stephen F. Burns, Masashi Miyashita, David J. Stensel

    BRITISH JOURNAL OF NUTRITION   108 ( 10 ) 1773 - 1779  2012年11月

     概要を見る

    Foods high in monounsaturated fat, such as olive oil, and endurance exercise are both known to independently reduce postprandial TAG concentrations. We examined the combined effects of exercise and dietary fat composition on postprandial TAG concentrations in nine healthy pre-menopausal females (age 26.8 (SD 3.3) years, BMI 22.3 (SD 2.0) kg/m(2)). Each participant completed four, 2d trials in a randomised order: (1) butter-no exercise, (2) olive oil-no exercise, (3) butter-exercise, (4) olive oil-exercise. On day 1 of the exercise trials, participants walked or ran on a treadmill for 60min. On the no-exercise trials, participants rested on day 1. On day 2 of each trial, participants rested and consumed an olive oil meal (saturated fat 15% and unsaturated fat 85 %) or a butter meal (saturated fat 71% and unsaturated fat 29 %) for breakfast. Venous blood samples were obtained in the fasted state and for 6 h postprandially on day 2. A significant main effect on physical activity (exercise or control) was obtained for plasma TAG concentration (three-way ANOVA, P=0.043), and the total area under the concentration v. time curve for TAG was 26% lower on the olive oil-exercise trial (4.40 (SD 0.40) mmol x 6 h/l) than the butter-no exercise trial (5.91 (SD 1.01) mmol x 6 h/l) (one-way ANOVA, P=0.029). These findings suggest that the combination of exercise and a preference for monounsaturated dietary fat intake in the form of olive oil may be most beneficial for reducing postprandial TAG concentrations.

    DOI

  • Accumulating exercise and postprandial lipaemia

    Miyashita Masashi, Burns Stephen F, Stensel David J

    The journal of physical fitness and sports medicine : JPFSM   1 ( 3 ) 541 - 545  2012年09月  [査読有り]

     概要を見る

    Cardiovascular disease is a major cause of death in many developed countries. Impaired clearance of postprandial triacylglycerol has been associated with an increase in cardiovascular disease risk. Physical activity can reduce many cardiovascular disease risk factors including postprandial triacylglycerol concentrations. Public health guidelines suggest that physical activity can be accumulated in several short bouts throughout the day, with a minimum duration of 10 minutes per activity bout. Until recently, limited evidence was available to support the effect of accumulating physical activity on postprandial lipaemia. Thus, the authors conducted a series of investigations to examine the influence of accumulated physical activity on postprandial lipaemia. The implications of the research findings are discussed in keeping with practical guidance for those wishing to engage in exercise that will lower postprandial triacylglycerol concentrations.

    DOI CiNii

  • A 12-week after-school physical activity programme improves endothelial cell function in overweight and obese children: a randomised controlled study

    Jong-Hwan Park, Masashi Miyashita, Yoo-Chan Kwon, Hyun-Tae Park, Eun-Hee Kim, Jin-Kee Park, Ki-Beam Park, Suk-Ran Yoon, Jin-Woong Chung, Yoshio Nakamura, Sang-Kab Park

    BMC PEDIATRICS   12   111 -  2012年07月

     概要を見る

    Background: Endothelial dysfunction is associated with childhood obesity and is closely linked to the amount and function of endothelial progenitor cells. However, it remains unclear whether endothelial progenitor cells increase with after-school exercise in overweight and obese children. The purpose of this study was to investigate the effects of an after-school exercise programme on endothelial cell function in overweight and obese children.
    Methods: A total of 29 overweight/obese children (12.2 +/- 0.1 years) were randomly divided into control (i.e. no after-school exercise, n = 14) and after-school exercise (n = 15) groups. The 12-week after-school exercise intervention consisted of 3 days of combined aerobic and resistance exercise per week. Each 80-minute exercise programme included 10 minutes of warm-up and 10 minutes of cool-down after school. CD34(+) (a cell surface marker on hematopoietic stem cells), CD133(+) (a cell surface marker on hematopoietic progenitor cells) and CD34(+)/CD133(+) (considered as endothelial progenitor cells) were measured at baseline and after 12 weeks using flow cytometry.
    Results: Increased percentages of CD34(+), CD133(+) and CD34(+)/CD133(+) cells were observed in the after-school exercise group (p = 0.018; p = 0.001; p = 0.002, respectively) compared with the control group. Carotid intima-media thickness decreased after 12 weeks in the after-school exercise group (p = 0.020) compared with the control group.
    Conclusions: This study provides preliminary evidence that a combined after-school exercise programme may represent an effective intervention strategy for improving vascular repair and endothelial cell function, leading to improved cardiovascular health in overweight and obese children.

    DOI

  • Psychological, social, and environmental factors associated with utilization of senior centers among older adults in Korea

    Hyun-Shik Kim, Masashi Miyashita, Kazuhiro Harada, Jong-Hwan Park, Jae-Moo So, Yoshio Nakamura

    Journal of Preventive Medicine and Public Health   45 ( 4 ) 244 - 250  2012年07月

     概要を見る

    Objectives: The purpose of the study was to examine the relationships among the psychological, social, and environmental factors influencing the utilization of senior centers among older adults in Korea. Methods: A questionnaire survey was administered to two types of older adults who lived in Seoul, Korea: 262 older adults who used senior centers (3 places) and 156 older adults who did not use senior centers. Results: Our results showed clearly that the utilization of the senior centers in Korea is affected by higher self-efficacy (odds ratio [OR], 6.08
    95% confidence interval [CI], 3.31 to 12.32), higher perceived benefits (OR, 1.71
    95% CI, 1.16 to 4.36), lower perceived barriers (OR, 6.43
    95% CI, 3.07 to 11.45), higher family support (OR, 4.21
    95% CI, 2.02 to 8.77), and higher support from friends (OR, 4.08
    95% CI, 2.38 to 7.81). The results also showed that participants whose total travel time was 15 to 29 minutes (OR, 2.84
    95% CI, 1.21 to 3.64) or less than 14 minutes (OR, 4.68
    95% CI, 3.41 to 8.41) were more likely to use a senior center than those who had to travel more than 30 minutes. Conclusions: This study showed that the utilization of senior centers in Korea is affected by psychological, social, and environmental factors, specifically by self-efficacy, perceived benefits, perceived barriers, social support, convenience of transportation, and total travel time to the senior centers. The effects of longer-term utilization of the senior centers by non-users on health-related outcomes in a large population warrant attention. Copyright © 2012 The Korean Society for Preventive Medicine.

    DOI PubMed

  • Appetite after rope skipping may differ between males and females

    Hiroshi Kawano, Fumiya Motegi, Takafumi Ando, Yuko Gando, Mayuko Mineta, Shigeharu Numao, Masashi Miyashita, Shizuo Sakamoto, Mitsuru Higuchi

    OBESITY RESEARCH & CLINICAL PRACTICE   6 ( 2 ) E121 - E127  2012年04月  [査読有り]

     概要を見る

    Background: When previously sedentary males and females follow the same exercise training programs with ad libitum feeding, males reduced body mass, but females do not, which suggests that females may increase appetite in response to exercise training compared with males. Rope skipping is traditional exercise modality that everyone had experienced during elementary school years in Japan. The purpose of this study was to determine whether there is a sex difference on appetite after acute rope skipping exercise.
    Methods and results: Thirteen healthy young males (22.5 +/- 0.8 years, 172.2 +/- 1.7 cm, 68.8 +/- 2.3 kg, 18.4 +/- 0.9%) and 13 females (22.9 +/- 0.8 years, 160.6 +/- 1.5 cm, 52.9 +/- 1.6 kg, 25.0 +/- 1.0%) participated in this study. Subjects consumed their lunch by 13:00, and performed a total of 20 min rope skipping exercise (2 sets x 10 min with 5 min interval) from 16:00. In females, appetite significantly increased from immediately after the exercise to 30 min after the exercise (from 13 mm to 30 mm), but remained unchanged in males. Although heart rate, ratings of perceived exertion, and lactate concentrations increased from baseline to immediately after exercise, there were no differences in the increase between males and females. Blood glucose concentrations at baseline and 30 min after exercise were higher in females than in males.
    Conclusion: These results indicated that rope skipping exercise induces an increase in appetite in females, but not in males. This increased appetite in females after the rope skipping exercise was induced without change in blood glucose concentrations. (C) 2011 Asian Oceanian Association for the Study of Obesity. Published by Elsevier Ltd. All rights reserved.

    DOI

  • Effect of weight loss on maximal fat oxidation rate in obese men

    Takehiko Tsujimoto, Hiroyuki Sasai, Masashi Miyashita, Miki Eto, Rina So, Hiroyuki Ohkubo, Kiyoji Tanaka

    OBESITY RESEARCH & CLINICAL PRACTICE   6 ( 2 ) E111 - E119  2012年04月  [査読有り]

     概要を見る

    Introduction: The hallmark features of obesity include insulin resistance and an impaired ability to oxidize lipids. As compared to exercise training, it remains relatively unclear if diet-induced weight loss can also induce fat metabolism. This study was undertaken to examine the effects of diet-induced weight loss on fat metabolism during a single session of exercise in middle-aged obese men. Methods: Fifteen obese men who were otherwise healthy (average age of 53.5 +/- 6.9 yr and average body mass index of 27.8 +/- 1.6 kg/m(2)) participated in a 12-wk weight loss program primarily consisting of dietary modification. Maximal fat oxidation (MFO) rates, MFO per lean body mass (MFOLBM) and insulin resistance (HOMA-IR) were measured before and after the program. Participants performed a 24-min graded exercise test on a cycle ergometer, with 15-W increments every 4 min. Expired gas analysis was performed by indirect calorimetry, and nonprotein respiratory quotient equations were used to calculate fat oxidation rates. Results: The weight (-8.3 +/- 3.8 kg), fat mass (-4.5 +/- 1.9 kg), and lean body mass (-3.8 +/- 2.4 kg) (P &lt; 0.001 for all measurements) of the participants were decreased at the end of the 12-wk program. The MFO tended to increase by 19% (P = 0.08) and MFOLBM significantly increased by 28.8% (P = 0.02). Although insulin resistance also significantly decreased by 49% (P &lt; 0.001), changes in fat oxidation variables did not correlate with changes in insulin resistance. Conclusion: Diet-induced weight loss improves fat metabolism with the improvement in insulin resistance. (C) 2011 Asian Oceanian Association for the Study of Obesity. Published by Elsevier Ltd. All rights reserved.

    DOI

  • 身体活動と食後高中性脂肪血症:活動的な生活への実用的アプローチ

    宮下政司

    医学のあゆみ   240 ( 10 ) 855 - 857  2012年

  • 食欲を抑制させる運動様式の探索

    河野寛, 宮下政司, 沼尾成晴, 丸藤祐子, 坂本静男, 樋口満

    財団法人明治安田厚生事業団 健康医科学研究助成論文集   27   52 - 61  2012年

  • The effect of exercise timing on postprandial lipaemia

    Miyashita M, Stensel DJ, Burns SF

    Journal of Atherosclerosis and Thrombosis   19 ( 2 ) 205 - 206  2012年

    DOI

  • メタボリックシンドロームに対する低強度運動の有効性:運動習慣と日常での身体活動の観点から

    原田和弘, 宮下政司

    健康支援   14 ( 2 ) 1 - 5  2012年

  • Physical Activity Status and Postprandial Lipaemia in Older Adults

    M. Miyashita, J. -H. Park, M. Takahashi, S. Burns, H. -S. Kim, K. Suzuki, Y. Nakamura

    INTERNATIONAL JOURNAL OF SPORTS MEDICINE   32 ( 11 ) 829 - 834  2011年11月

     概要を見る

    Physical activity-induced lowering of postprandial lipaemia is short-lived. However, little is known regarding the role of physical activity status on postprandial lipaemia. The purpose of the present study was to compare postprandial triacylglycerol concentrations in active and inactive older adults. A total of 26 older adults (aged 69.8 +/- 0.9 years, mean +/- SEM; 10 male and 16 female) were analysed in a cross-sectional design. Based on accelerometer data, participants were divided into either the active group (&gt;= 150 min/week of moderate-intensity physical activity, n = 15) or the inactive group (&lt; 150 min/week of moderate-intensity physical activity, n = 11). After a 48-h period of physical activity avoidance and a 10-h overnight fast, participants consumed a test meal of moderate fat content (35%). Capillary blood samples were collected in the fasted state and at 2, 4, and 6 h postprandially. After adjusting for fasting triacylglycerol concentrations, body mass, body mass index and waist circumference, postprandial capillary triacylglycerol concentrations were significantly lower in the active than inactive group (P = 0.046). These findings demonstrate that regular physical activity lowers postprandial lipaemia independent of the acute effects of physical activity in older adults.

    DOI

  • Use of senior center and the health-related quality of life in Korean older adults

    Hyun-Shik Kim, Kazuhiro Harada, Masashi Miyashita, Eun-A. Lee, Jin-Kee Park, Yoshio Nakamura

    Journal of Preventive Medicine and Public Health   44 ( 4 ) 149 - 156  2011年07月  [査読有り]

     概要を見る

    Objective: The purpose of the present study was to examine the relationship between the use of senior center and health-related quality of life in Korean older adults. Methods: A questionnaire survey was conducted to two types of older adults who lived in Busan, Korea: 154 older adults who used a senior center and 137 older adults who did not use a senior center. The Korean version of short-form 36-item health survey was administered to assess the health-related quality of life. Demographic variables were obtained from a questionnaire. These were gender, age, family status, marital status, education, monthly income, present illness, body mass index and physical activity. Results: The 8-domain scales of physical function and role-physical were significantly higher in the users of the senior center compared with the non-users (F=4.87, p=0.027 and F=7.02, p=0.009, respectively). The 8-domain scales of vitality was also significantly higher in the users of the senior center compared with the non-users (F=7.48, p=0.007). Conclusions: The present study showed that the users of the senior center have higher physical function, role-physical and vitality compared with the non-users. These findings suggest that although the results are unable to specify causal relationships using the senior center may lead to some improvement in health-related quality of life.

    DOI PubMed

  • The effects of 30 min of exercise on cardiovascular disease risk factors in healthy and obese individuals

    Masashi Miyashita, David J. Stensel, Stephen F. Burns, Hiroyuki Sasai, Kiyoji Tanaka

    ATHEROSCLEROSIS   216 ( 2 ) 496 - 497  2011年06月

    速報,短報,研究ノート等(学術雑誌)  

    DOI PubMed

  • The effects of 30 min of exercise on cardiovascular disease risk factors in healthy and obese individuals

    Masashi Miyashita, David J. Stensel, Stephen F. Burns, Hiroyuki Sasai, Kiyoji Tanaka

    ATHEROSCLEROSIS   216 ( 2 ) 496 - 497  2011年06月  [査読有り]

    速報,短報,研究ノート等(学術雑誌)  

    DOI

  • Oxidised low-density lipoprotein concentrations and physical activity status in older adults: The WASEDA active life study

    Jong-Hwan Park, Masashi Miyashita, Masaki Takahashi, Kazuhiro Harada, Kanae Takaizumi, Hyun-Shik Kim, Katsuhiko Suzuki, Yoshio Nakamura

    Journal of Atherosclerosis and Thrombosis   18 ( 7 ) 568 - 573  2011年

     概要を見る

    Aim: Oxidised low-density lipoprotein (LDL) is considered a risk marker for cardiovascular disease. However, it remains unclear whether oxidised LDL concentrations differ with the physical activity status in older adults. The purpose of this study was to examine the relationship between the amount of physical activity and oxidised LDL in older adults. Methods: Twenty-seven older adults (aged 69.9 ± 4.3 years, mean ± SD.
    16 female and 11 male) were analysed in the cross-sectional design. Prior to blood collection, participants were asked to wear an uniaxial accelerometer for 4 consecutive weeks to determine the physical activity status. After a 48-h period of physical activity avoidance and a 10-h overnight fast, fasting venous blood samples were obtained from each participant. Results: Fasting plasma oxidised LDL concentrations and plasma monocyte chemoattractant protein- 1 concentrations were negatively correlated with the amount of physical activity (r = -0.409, p = 0.034
    r = -0.385, p = 0.047, respectively). Conclusions: This study demonstrates that regular physical activity may play a protective role in the oxidation of LDL in older adults.

    DOI PubMed

  • Use of senior center and the health-related quality of life in Korean older adults.

    Kim Hyun Shik, Harada Kazuhiro, Miyashita Masashi, Lee Eun A, Park Jin Kee, Nakamura Yoshio

    Journal of preventive medicine and public health = Yebang Ŭihakhoe chi   44 ( 4 )  2011年

     概要を見る

    OBJECTIVE:The purpose of the present study was to examine the relationship between the use of senior center and health-related quality of life in Korean older adults.;METHODS:A questionnaire survey was conducted to two types of older adults who lived in Busan, Korea: 154 older adults who used a senior center and 137 older adults who did not use a senior center. The Korean version of short-form 36-item health survey was administered to assess the health-related quality of life. Demographic variables were obtained from a questionnaire. These were gender, age, family status, marital status, education, monthly income, present illness, body mass index and physical activity.;RESULTS:The 8-domain scales of physical function and role-physical were significantly higher in the users of the senior center compared with the non-users (F=4.87, p=0.027 and F=7.02, p=0.009, respectively). The 8-domain scales of vitality was also significantly higher in the users of the senior center compared with the non-users (F=7.48, p=0.007).;CONCLUSIONS:The present study showed that the users of the senior center have higher physical function, role-physical and vitality compared with the non-users. These findings suggest that although the results are unable to specify causal relationships using the senior center may lead to some improvement in health-related quality of life.

    DOI

  • 有酸素性運動が中性脂肪の日内変動に及ぼす影響:生活活動下における簡易測定器による評価

    宮下政司, 高泉佳苗, 中村好男

    デサントスポーツ科学   32   81 - 87  2011年

    CiNii

  • 動脈硬化進展予防に対する身体活動の役割:身体活動と新規動脈硬化症予測マーカーとの関連

    宮下政司, 朴鍾煥, 高橋将記, 鈴木克彦, 中村好男

    財団法人健康管理事業団 研究助成論文集   27   39 - 47  2011年

  • Accumulating short bouts of running reduces resting blood pressure in young normotensive/pre-hypertensive men

    Masashi Miyashita, Stephen F. Burns, David J. Stensel

    JOURNAL OF SPORTS SCIENCES   29 ( 14 ) 1473 - 1482  2011年  [査読有り]

     概要を見る

    In this study, we compared the effects of accumulated and continuous running on resting arterial blood pressure. Ten normotensive/pre-hypertensive men, aged 25.0 +/- 4.2 years (mean +/- s), participated in three 2-day trials at least one week apart in a randomized, repeated-measures design. On Day 1, participants rested (control) or ran at 70% of maximum oxygen uptake in either ten 3-min bouts (30 min rest between bouts) or one continuous 30-min bout. On Day 2, participants rested throughout the day. Blood pressure was measured at hourly intervals throughout Days 1 and 2. Mean resting systolic blood pressure on Day 2 was 6% lower during the accumulated and continuous running trials compared with the control trial (110 +/- 6 vs. 110 +/- 8 vs. 117 +/- 6 mmHg respectively; P &lt; 0.05), but there were no differences in resting diastolic blood pressure among the three trials (70 +/- 7 vs. 69 +/- 6 vs. 70 +/- 5 mmHg respectively). These findings demonstrate that accumulating 30 min of running throughout the day in short bouts is as effective as 30 min of continuous running for reducing resting systolic blood pressure on the next day in young normotensive/pre-hyptertensive men.

    DOI

  • Oxidised Low-Density Lipoprotein Concentrations and Physical Activity Status in Older Adults: The WASEDA Active Life Study

    Jong-Hwan Park, Masashi Miyashita, Masaki Takahashi, Kazuhiro Harada, Kanae Takaizumi, Hyun-Shik Kim, Katsuhiko Suzuki, Yoshio Nakamura

    JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS   18 ( 7 ) 568 - 573  2011年  [査読有り]

     概要を見る

    Aim: Oxidised low-density lipoprotein (LDL) is considered a risk marker for cardiovascular disease. However, it remains unclear whether oxidised LDL concentrations differ with the physical activity status in older adults. The purpose of this study was to examine the relationship between the amount of physical activity and oxidised LDL in older adults.
    Methods: Twenty-seven older adults (aged 69.9 +/- 4.3 years, mean +/- SD.; 16 female and 11 male) were analysed in the cross-sectional design. Prior to blood collection, participants were asked to wear an uniaxial accelerometer for 4 consecutive weeks to determine the physical activity status. After a 48-h period of physical activity avoidance and a 10-h overnight fast, fasting venous blood samples were obtained from each participant.
    Results: Fasting plasma oxidised LDL concentrations and plasma monocyte chemoattractant protein-1 concentrations were negatively correlated with the amount of physical activity (r = -0.409, p = 0.034; r = -0.385, p = 0.047, respectively).
    Conclusions: This study demonstrates that regular physical activity may play a protective role in the oxidation of LDL in older adults.

    DOI

  • Physical activity status and postprandial lipaemia in older adults

    M. Miyashita, J. H. Park, M. Takahashi, S. Burns, H. S. Kim, K. Suzuki, Y. Nakamura

    International Journal of Sports Medicine   32 ( 11 ) 829 - 834  2011年  [査読有り]

     概要を見る

    Physical activity-induced lowering of postprandial lipaemia is short-lived. However, little is known regarding the role of physical activity status on postprandial lipaemia. The purpose of the present study was to compare postprandial triacylglycerol concentrations in active and inactive older adults. A total of 26 older adults (aged 69.8±0.9 years, mean±SEM
    10 male and 16 female) were analysed in a cross-sectional design. Based on accelerometer data, participants were divided into either the active group (150min/week of moderate-intensity physical activity, n=15) or the inactive group (&lt
    150min/week of moderate-intensity physical activity, n=11). After a 48-h period of physical activity avoidance and a 10-h overnight fast, participants consumed a test meal of moderate fat content (35%). Capillary blood samples were collected in the fasted state and at 2, 4, and 6h postprandially. After adjusting for fasting triacylglycerol concentrations, body mass, body mass index and waist circumference, postprandial capillary triacylglycerol concentrations were significantly lower in the active than inactive group (P=0.046). These findings demonstrate that regular physical activity lowers postprandial lipaemia independent of the acute effects of physical activity in older adults. © Georg Thieme Verlag KG Stuttgart · New York.

    DOI PubMed

  • Demographic and health-related characteristics associated with awareness of the long-term care insurance system in Korean older adults

    Kim H-S, Harada K, Miyashita M, Lee E, Park J-K, Nakamura Y

    Journal of Global Senior Health Promotion Institute   1 ( 1 ) 29 - 40  2011年

  • 断眠の交感神経副腎髄質系およびHPA系に及ぼす影響:唾液中ストレス指標による検討

    小西真幸, 高橋将記, 遠藤直哉, 沼尾成晴, 高木俊, 宮下政司, 緑川泰史, 鈴木克彦, 坂本静男

    日本臨床生理学会会誌   41 ( 3 ) 129 - 135  2011年

  • Influence of prolonged treadmill running on appetite, energy intake and circulating concentrations of acylated ghrelin

    James A. King, Masashi Miyashita, Lucy K. Wasse, David J. Stensel

    APPETITE   54 ( 3 ) 492 - 498  2010年06月

     概要を見る

    The effects of prolonged treadmill running on appetite, energy intake and acylated ghrelin (an appetite stimulating hormone) were examined in 9 healthy males over the course of 24 h. Participants completed 2 experimental trials (exercise and control) in a randomised-crossover fashion. In the exercise trial participants ran for 90 min at 68.8 +/- 0.8% of maximum oxygen uptake followed by 8.5 h of rest. Participants returned to the laboratory on the following morning to provide a fasting blood sample and ratings of appetite (24 h measurement). No exercise was performed on the control trial. Appetite was measured within the laboratory using visual analogue scales and energy intake was assessed from ad libitum buffet meals. Acylated ghrelin was determined from plasma using an ELISA assay. Exercise transiently suppressed appetite and acylated ghrelin but each remained no different from control values in the hours afterwards. Furthermore, despite participants expending 5324 kJ during exercise there was no compensatory increase in energy intake (24 h energy intake; control 17,191 kJ, exercise 17,606 kJ). These findings suggest that large energy deficits induced by exercise do not lead to acute compensatory responses in appetite, energy intake or acylated ghrelin. (C) 2010 Elsevier Ltd. All rights reserved.

    DOI PubMed CiNii

  • Influence of prolonged treadmill running on appetite, energy intake and circulating concentrations of acylated ghrelin

    James A. King, Masashi Miyashita, Lucy K. Wasse, David J. Stensel

    Appetite   54 ( 3 ) 492 - 498  2010年06月  [査読有り]

     概要を見る

    The effects of prolonged treadmill running on appetite, energy intake and acylated ghrelin (an appetite stimulating hormone) were examined in 9 healthy males over the course of 24. h. Participants completed 2 experimental trials (exercise and control) in a randomised-crossover fashion. In the exercise trial participants ran for 90. min at 68.8 ± 0.8% of maximum oxygen uptake followed by 8.5. h of rest. Participants returned to the laboratory on the following morning to provide a fasting blood sample and ratings of appetite (24. h measurement). No exercise was performed on the control trial. Appetite was measured within the laboratory using visual analogue scales and energy intake was assessed from ad libitum buffet meals. Acylated ghrelin was determined from plasma using an ELISA assay. Exercise transiently suppressed appetite and acylated ghrelin but each remained no different from control values in the hours afterwards. Furthermore, despite participants expending 5324. kJ during exercise there was no compensatory increase in energy intake (24. h energy intake
    control 17,191. kJ, exercise 17,606. kJ). These findings suggest that large energy deficits induced by exercise do not lead to acute compensatory responses in appetite, energy intake or acylated ghrelin. © 2010 Elsevier Ltd.

    DOI PubMed

  • Twelve-Week Jogging Training Increases Pre-Heparin Serum Lipoprotein Lipase Concentrations in Overweight/Obese Middle-Aged Men

    Masashi Miyashita, Miki Eto, Hiroyuki Sasai, Takehiko Tsujimoto, Yasuhiro Nomata, Kiyoji Tanaka

    JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS   17 ( 1 ) 21 - 29  2010年  [査読有り]

     概要を見る

    Aim: Enhancement of lipoprotein lipase (LPL) activity through drug administration has been shown to increase pre-heparin serum LPL concentrations; however, pre-heparin serum LPL responses to exercise training have not been determined. The present study was undertaken to investigate the effects of 12 weeks of supervised aerobic exercise training on pre-heparin serum LPL concentrations in overweight/obese men.
    Methods: Fifteen overweight/obese middle-aged men were assigned to one of two 12-week supervised exercise interventions: a walking group (eight participants gradually increasing brisk walking to 60 min/day 3 days a week) or a jogging group (seven participants gradually increasing jogging to 60 min/day 3 days a week). All participants maintained ad libitum diets. Blood samples were collected at baseline and immediately after 12 weeks. The primary outcome was pre-heparin serum LPL.
    Results: Pre-heparin serum LPL concentrations were increased in the jogging group after 12 weeks compared with the baseline values (mean +/- SEM: 37.6 +/- 4.7 vs. 51.0 +/- 6.6 ng/mL, respectively, p = 0.033). In the walking group, pre-heparin serum LPL concentrations remained unchanged after 12 weeks.
    Conclusions: This study demonstrates that 12 weeks of jogging training increases pre-heparin serum LPL concentrations in overweight/obese middle-aged men.

    DOI

  • Pre-heparin serum lipoprotein lipase concentrations in obese men of contrasting physical activity status: A preliminary study

    Masashi Miyashita, Miki Eto, Hiroyuki Sasai, Takehiko Tsujimoto, Rina So, Yasuhiro Nomata, Kiyoji Tanaka

    Journal of Atherosclerosis and Thrombosis   17 ( 10 ) 1110 - 1112  2010年

    速報,短報,研究ノート等(学術雑誌)  

    DOI

  • Postprandial capillary triacylglycerol responses in centrally obese middle-aged men to moderate exercise

    Miyashita M, Sasai H, Tanaka K

    Journal of Sports Sciences   28 ( 12 ) 1269 - 1275  2010年

    DOI

  • 中年過体重・肥満者における異なる運動強度による運動が新規脂質・炎症マーカーに及ぼす影響

    宮下政司, 田中喜代次

    財団法人明治安田厚生事業団 健康医科学研究助成論文集   25   121 - 128  2010年

  • 生活指導の立場から:肥満に対する運動と食事療法の寄与度について

    宮下政司, 田中喜代次

    日本臨床スポーツ医学会誌   18 ( 2 ) 251 - 253  2010年

  • 運動における食後中性脂肪の上昇抑制効果:最近の実証研究からの報告

    宮下政司

    肥満研究   16 ( 2 ) 100 - 104  2010年

  • Pre-heparin serum lipoprotein lipase concentrations in obese men of contrasting physical activity status: A preliminary study

    Miyashita M, Eto M, Sasai H, Tsujimoto T, So R, Nomata Y, Tanaka K

    Journal of Atherosclerosis and Thrombosis   17 ( 1 ) 1110 - 1112  2010年

    DOI

  • Twelve-week jogging training increases pre-heparin serum lipoprotein lipase concentrations in overweight/obese middle-aged men

    Miyashita M, Eto M, Sasai H, Tsujimoto T, Nomata Y, Tanaka K

    Journal of Atherosclerosis and Thrombosis   17 ( 10 ) 21 - 29  2010年

    DOI

  • Post-prandial capillary triacylglycerol responses in centrally obese middle-aged men to moderate exercise

    Miyashita M, Sasai H, Tanaka K

    Journal of Sports Sciences   28 ( 12 ) 1269 - 1275  2010年

    DOI

  • Acute Effects of Accumulating Exercise on Postprandial Lipemia and C-Reactive Protein Concentrations in Young Men

    Masashi Miyashita, Stephen F. Burns, David J. Stensel

    INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM   19 ( 6 ) 569 - 582  2009年12月

     概要を見る

    The current study investigated the acute effects of accumulating short bouts of running on circulating concentrations of postprandial triacylglycerol (TAG) and C-reactive protein (CRP). Ten men, age 21-32 yr, completed two 1-d trials. On 1 occasion participants ran at 70% of maximum oxygen uptake in six 5-min bouts (i.e., 8:30, 10, and 11:30 a.m. and 1, 2:30, and 4 p.m.) with 85 min rest between runs. On another occasion participants rested throughout the day. In both trials, participants consumed test meals at 9 a.m. and 12 p.m. In each trial, venous blood samples were collected at 8:30, 10, and 11:30 a.m. and 1, 2:30, 4, and 5:30 p.m. for plasma TAG measurement and at 8:30 a.m. and 5:30 p.m. for serum CRP measurement. Total area under the curve for plasma TAG concentration versus time was 10% lower on the exercise trial than the control trial (M +/- SEM: 13.5 +/- 1.8 vs. 15.0 +/- 1.9 mmol . 9 hr(-1) . L(-1); p = .004). Serum CRP concentrations did not differ between trials or over time. This study demonstrates that accumulating short bouts of running reduces postprandial plasma TAG concentrations (a marker for cardiovascular disease risk) but does not alter serum CRP concentrations.

  • Acute Effects of Accumulating Exercise on Postprandial Lipemia and C-Reactive Protein Concentrations in Young Men

    Masashi Miyashita, Stephen F. Burns, David J. Stensel

    INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM   19 ( 6 ) 569 - 582  2009年12月

     概要を見る

    The current study investigated the acute effects of accumulating short bouts of running on circulating concentrations of postprandial triacylglycerol (TAG) and C-reactive protein (CRP). Ten men, age 21-32 yr, completed two 1-d trials. On 1 occasion participants ran at 70% of maximum oxygen uptake in six 5-min bouts (i.e., 8:30, 10, and 11:30 a.m. and 1, 2:30, and 4 p.m.) with 85 min rest between runs. On another occasion participants rested throughout the day. In both trials, participants consumed test meals at 9 a.m. and 12 p.m. In each trial, venous blood samples were collected at 8:30, 10, and 11:30 a.m. and 1, 2:30, 4, and 5:30 p.m. for plasma TAG measurement and at 8:30 a.m. and 5:30 p.m. for serum CRP measurement. Total area under the curve for plasma TAG concentration versus time was 10% lower on the exercise trial than the control trial (M +/- SEM: 13.5 +/- 1.8 vs. 15.0 +/- 1.9 mmol . 9 hr(-1) . L(-1); p = .004). Serum CRP concentrations did not differ between trials or over time. This study demonstrates that accumulating short bouts of running reduces postprandial plasma TAG concentrations (a marker for cardiovascular disease risk) but does not alter serum CRP concentrations.

  • AEROBIC EXERCISE AND POSTPRANDIAL LIPEMIA: ISSUES ON VOLUME AND FREQUENCY OF EXERCISE

    Masashi Miyashita, David Stensel

    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE   41 ( 4 ) 965 - 965  2009年04月

    速報,短報,研究ノート等(学術雑誌)  

    DOI

  • Aerobic exercise and postprandial lipemia: Issues on volume and frequency of exercise

    Miyashita, Masashi, Stensel, David

    Medicine and Science in Sports and Exercise   41 ( 4 ) 965 -  2009年04月  [査読有り]

    DOI

  • Report: Lectures by a UK expert on exercise and appetite regulation

    Miyashita M

    Sport Sciences   6   116 - 118  2009年

  • メタボリックシンドロームの予防・改善の向けた運動のすすめ ~食後中性脂肪の動態に着眼して

    宮下政司, 田中喜代次

    体育の科学   59 ( 11 ) 761 - 765  2009年

  • Accumulating short bouts of brisk walking reduces postprandial plasma triacylglycerol concentrations and resting blood pressure in healthy young men

    Masashi Miyashita, Stephen F. Burns, David J. Stensel

    AMERICAN JOURNAL OF CLINICAL NUTRITION   88 ( 5 ) 1225 - 1231  2008年11月

     概要を見る

    Background: Physical activity recommendations promote the accumulation of aerobic activity in bouts of &gt;= 10 min. It is important to determine whether shorter bouts of activity can influence health.
    Objective: We compared the effects of accumulating ten 3-min bouts of brisk walking with those of one 30-min bout of brisk walking on postprandial plasma triacylglycerol concentrations and resting blood pressure.
    Design: Fifteen healthy young men completed three 2-d trials &gt;= 1 wk apart in a randomized, repeated-measures design. On day 1, subjects rested (no exercise) or walked briskly in either ten 3-min bouts (30 min rest between each) or one 30-min bout (gross energy expenditure: 1.10 MJ/30 min). On day 2, subjects rested and consumed high-fat test meals for breakfast and lunch.
    Results: On day 2 area under the plasma triacylglycerol concentration over time curve was 16% lower on the accumulated and continuous brisk walking trials than on the control trial ((x) over bar +/- SEM: 9.98 +/- 0.67 compared with 9.99 +/- 0.76 compared with 11.90 +/- 1.02 mmol center dot 7h/L, respectively; P = 0.005, one-factor ANOVA). Resting systolic blood pressure was 6-7% lower throughout day 2 on the accumulated and continuous trials than on the control trial (109 +/- 1 compared with 110 +/- 1 compared with 117 +/- 2 mm Hg, respectively; P &lt; 0.0005).
    Conclusion: Accumulating 30 min of brisk walking in short (3-min) bouts is equally effective in reducing postprandial lipemia and systolic blood pressure as is one continuous 30-min bout. Am J Clin Nutr 2008; 88: 1225-31.

    DOI

  • Effects of continuous versus accumulated activity patterns on postprandial triacylglycerol concentrations in obese men

    M. Miyashita

    International Journal of Obesity   32 ( 8 ) 1271 - 1278  2008年08月

     概要を見る

    Objective: There is limited information regarding the effects of short (&lt
    10 min) bouts of activity on postprandial lipaemia and no studies are available regarding the effects of short bouts of activity on postprandial lipaemia in obese men. The objective of this study was to compare the effects of accumulating ten, 3-min bouts of exercise versus one 30 min bout of exercise on postprandial serum triacylglycerol (TAG) concentrations in obese men. Design: Each subject completed three 2-day trials at least 1 week apart in a randomized, repeated-measures design. On day 1, subjects rested (no exercise) or cycled at 60% of maximum heart rate in either ten, 3-min bouts (30 min rest between each), or one continuous 30-min bout. On day 2 of each trial, after an overnight fast, the subjects consumed a standardized test meal for breakfast. Venous blood samples were obtained in the fasted state (0 h), and 2, 4 and 6 h postprandially on day 2. Subjects: Eight sedentary men (age: 27±2 years) with body mass index between 25 and 37 kg/m2. Measurements: Postprandial TAG, non-esterified fatty acids, 3-hydroxybutyrate, insulin and glucose were determined. Results: Total area under the postprandial serum TAG concentrations versus time curve was 18% (P=0.042) and 15% (P=0.032) lower throughout day 2 of both the accumulated exercise trial and the continuous exercise trial, respectively, compared with the control trial with little difference between exercise trials. Conclusion: At 30 min of moderate cycling (0.87 MJ per 30 min) accumulated in short bouts is equally effective in reducing postprandial serum TAG concentrations as one continuous 30 min bout of cycling in obese men. © 2008 Macmillan Publishers Limited All rights reserved.

    DOI PubMed

  • Moderate exercise reduces serum triacylglycerol concentrations but does not affect pre-heparin lipoprotein lipase concentrations after a moderate-fat meal in young men

    Masashi Miyashita, Kumpei Tokuyama

    BRITISH JOURNAL OF NUTRITION   99 ( 5 ) 1076 - 1082  2008年05月

     概要を見る

    Aerobic exercise has been shown to lower postprandial TAG concentrations after a meal(s) of high-fat content. This study examined the effects of moderate-intensity cycling on postprandial TAG concentrations and pre-heparin lipoprotein lipase concentrations after subjects consumed a meal of moderate-fat content (45 % of total energy). Twelve male subjects, aged 24 (SEM 1) years, completed two 2 d trials (exercise and control) at least I week apart in a randomised, repeated measures design. On day 1, subjects either cycled for 30 min at 65 % of maximum heart rate in the afternoon or rested (no exercise). On day 2 of both trials, after an overnight stay with an I I h fast, subjects consumed a test meal of moderate-fat content (0.61 g fat, 1.34 g carbohydrate, 0.37 g protein and 51 kJ energy/kg body mass) for breakfast. Blood samples were collected at baseline (before the exercise or at an equivalent time-point during the control trial on day 1). in the fasted state (0 h) and at 2, 4 and 6 h postprandially on day 2. The total and incremental areas under the serum TAG concentration v. time curve were 30 % (P = 0.039) and 33 % (P = 0.012) lower on the exercise trial compared with the control trial, respectively. Serum pre-heparin lipoprotein lipase concentrations did not differ between the exercise and control trials. These findings demonstrate that 30 min of moderate-intensity cycling performed the day before a meal of moderate-fat content is effective at lowering postprandial serum TAG concentrations but does not affect serum pre-heparin lipoprotein lipase concentrations in young men.

    DOI

  • Moderate exercise reduces serum triacylglycerol concentrations but does not affect pre-heparin lipoprotein lipase concentrations after a moderate-fat meal in young men

    Masashi Miyashita, Kumpei Tokuyama

    BRITISH JOURNAL OF NUTRITION   99 ( 5 ) 1076 - 1082  2008年05月  [査読有り]

     概要を見る

    Aerobic exercise has been shown to lower postprandial TAG concentrations after a meal(s) of high-fat content. This study examined the effects of moderate-intensity cycling on postprandial TAG concentrations and pre-heparin lipoprotein lipase concentrations after subjects consumed a meal of moderate-fat content (45 % of total energy). Twelve male subjects, aged 24 (SEM 1) years, completed two 2 d trials (exercise and control) at least I week apart in a randomised, repeated measures design. On day 1, subjects either cycled for 30 min at 65 % of maximum heart rate in the afternoon or rested (no exercise). On day 2 of both trials, after an overnight stay with an I I h fast, subjects consumed a test meal of moderate-fat content (0.61 g fat, 1.34 g carbohydrate, 0.37 g protein and 51 kJ energy/kg body mass) for breakfast. Blood samples were collected at baseline (before the exercise or at an equivalent time-point during the control trial on day 1). in the fasted state (0 h) and at 2, 4 and 6 h postprandially on day 2. The total and incremental areas under the serum TAG concentration v. time curve were 30 % (P = 0.039) and 33 % (P = 0.012) lower on the exercise trial compared with the control trial, respectively. Serum pre-heparin lipoprotein lipase concentrations did not differ between the exercise and control trials. These findings demonstrate that 30 min of moderate-intensity cycling performed the day before a meal of moderate-fat content is effective at lowering postprandial serum TAG concentrations but does not affect serum pre-heparin lipoprotein lipase concentrations in young men.

    DOI

  • Changes in substrate oxidation persist overnight after a marathon race

    Kaito Iwayama, Masashi Miyashita, Kumpei Tokuyama

    Japanese Journal of Physical Fitness and Sports Medicine   57 ( 1 ) 163 - 168  2008年

    DOI

  • Effects of continuous versus accumulated activity patterns on postprandial triacylglycerol concentrations in obese men.

    Miyashita M

    International journal of obesity (2005)   32 ( 8 ) 1271 - 1278  2008年  [査読有り]

     概要を見る

    OBJECTIVE:There is limited information regarding the effects of short (<10 min) bouts of activity on postprandial lipaemia and no studies are available regarding the effects of short bouts of activity on postprandial lipaemia in obese men. The objective of this study was to compare the effects of accumulating ten, 3-min bouts of exercise versus one 30 min bout of exercise on postprandial serum triacylglycerol (TAG) concentrations in obese men.;DESIGN:Each subject completed three 2-day trials at least 1 week apart in a randomized, repeated-measures design. On day 1, subjects rested (no exercise) or cycled at 60% of maximum heart rate in either ten, 3-min bouts (30 min rest between each), or one continuous 30-min bout. On day 2 of each trial, after an overnight fast, the subjects consumed a standardized test meal for breakfast. Venous blood samples were obtained in the fasted state (0 h), and 2, 4 and 6 h postprandially on day 2.;SUBJECTS:Eight sedentary men (age: 27+/-2 years) with body mass index between 25 and 37 kg/m(2).;MEASUREMENTS:Postprandial TAG, non-esterified fatty acids, 3-hydroxybutyrate, insulin and glucose were determined.;RESULTS:Total area under the postprandial serum TAG concentrations versus time curve was 18% (P=0.042) and 15% (P=0.032) lower throughout day 2 of both the accumulated exercise trial and the continuous exercise trial, respectively, compared with the control trial with little difference between exercise trials.;CONCLUSION:At 30 min of moderate cycling (0.87 MJ per 30 min) accumulated in short bouts is equally effective in reducing postprandial serum TAG concentrations as one continuous 30 min bout of cycling in obese men.

    DOI CiNii

  • 男性の肥満者における中強度の分散運動および一過性運動が食後中性脂肪濃度に及ぼす影響

    宮下政司

    財団法人健康管理事業団 研究助成論文集   24   33 - 43  2008年

  • 睡眠中のエネルギー代謝を測る

    片寄泰子, 宮下政司, 緒形ひとみ, 徳山薫平, 佐藤誠

    睡眠医療   2 ( 2 ) 192 - 198  2008年

    CiNii

  • Changes in substrate oxidation persist overnight after a marathon race

    Kaito Iwayama, Masashi Miyashita, Kumpei Tokuyama

    Japanese Journal of Physical Fitness and Sports Medicine   57 ( 1 ) 163 - 168  2008年

    DOI

  • 若年健常男性における短期間のビタミンEサプリメント摂取は長時間の反復運動後の炎症および筋損傷マーカーに影響を及ぼさない

    宮下政司, 朴鐘薫

    体力科学   57 ( 3 ) 383 - 391  2008年

    DOI

  • Accumulating short bouts of brisk walking reduces postprandial plasma triacylglycerol concentrations and resting blood pressure in healthy young men.

    Miyashita Masashi, Burns Stephen F, Stensel David J

    The American journal of clinical nutrition   88 ( 5 ) 1225 - 1231  2008年

     概要を見る

    BACKGROUND:Physical activity recommendations promote the accumulation of aerobic activity in bouts of >or=10 min. It is important to determine whether shorter bouts of activity can influence health.;OBJECTIVE:We compared the effects of accumulating ten 3-min bouts of brisk walking with those of one 30-min bout of brisk walking on postprandial plasma triacylglycerol concentrations and resting blood pressure.;DESIGN:Fifteen healthy young men completed three 2-d trials >or=1 wk apart in a randomized, repeated-measures design. On day 1, subjects rested (no exercise) or walked briskly in either ten 3-min bouts (30 min rest between each) or one 30-min bout (gross energy expenditure: 1.10 MJ/30 min). On day 2, subjects rested and consumed high-fat test meals for breakfast and lunch.;RESULTS:On day 2 area under the plasma triacylglycerol concentration over time curve was 16% lower on the accumulated and continuous brisk walking trials than on the control trial (x +/- SEM: 9.98 +/- 0.67 compared with 9.99 +/- 0.76 compared with 11.90 +/- 1.02 mmol x 7h/L, respectively; P = 0.005, one-factor ANOVA). Resting systolic blood pressure was 6-7% lower throughout day 2 on the accumulated and continuous trials than on the control trial (109 +/- 1 compared with 110 +/- 1 compared with 117 +/- 2 mm Hg, respectively; P < 0.0005).;CONCLUSION:Accumulating 30 min of brisk walking in short (3-min) bouts is equally effective in reducing postprandial lipemia and systolic blood pressure as is one continuous 30-min bout.

    DOI CiNii

  • 就寝直前の夕食が睡眠時のエネルギー代謝に及ぼす影響

    中村 和照, 宮下 政司, 緒形 ひとみ, 長坂 昌一郎, 徳山 薫平

    肥満研究 : 日本肥満学会誌 = Journal of Japan Society for the Study of Obesity   13 ( 3 ) 250 - 255  2007年12月  [査読有り]

  • Exercise-induced suppression of acylated ghrelin in humans

    D. R. Broom, D. J. Stensel, N. C. Bishop, S. F. Burns, M. Miyashita

    JOURNAL OF APPLIED PHYSIOLOGY   102 ( 6 ) 2165 - 2171  2007年06月

     概要を見る

    Ghrelin is an orexigenic hormone secreted from endocrine cells in the stomach and other tissues. Acylation of ghrelin is essential for appetite regulation. Vigorous exercise induces appetite suppression, but this does not appear to be related to suppressed concentrations of total ghrelin. This study examined the effect of exercise and feeding on plasma acylated Ghrelin and appetite. Nine male subjects aged 19-25 yr participated in two. 9-h trials (exercise and control) in a random crossover design. Trials began at 0800 in the morning after an overnight fast. In the exercise trial, subjects ran for 60 min at 72% of maximum oxygen uptake between 0800 and 0900. After this, they rested for 8 h and consumed a test meal at 1100. In the control trial, subjects rested for 9 h and consumed a test meal at 1100. Area under the curve values for plasma acylated ghrelin concentration (assessed from venous blood samples) were lower over the first 3 h and the full 9 h of the exercise trial compared with the control trial: 317 +/- 135 vs. 510 +/- 186 pg(.)ml(-1.)3 h and 917 +/- 342 vs. 1,401 +/- 521 pg(.)ml(-1.)9 h (means +/- S E) respectively (P &lt; 0.05). Area under the curve values for hunger (assessed using a visual scale) were lower over the first 3 h of the exercise trial compared with the control trial (P = 0.013). These findings demonstrate that plasma acylated ghrelin concentration and hunger are suppressed during running.

    DOI PubMed CiNii

  • Exercise-induced suppression of acylated ghrelin in humans

    D. R. Broom, D. J. Stensel, N. C. Bishop, S. F. Burns, M. Miyashita

    JOURNAL OF APPLIED PHYSIOLOGY   102 ( 6 ) 2165 - 2171  2007年06月  [査読有り]

     概要を見る

    Ghrelin is an orexigenic hormone secreted from endocrine cells in the stomach and other tissues. Acylation of ghrelin is essential for appetite regulation. Vigorous exercise induces appetite suppression, but this does not appear to be related to suppressed concentrations of total ghrelin. This study examined the effect of exercise and feeding on plasma acylated Ghrelin and appetite. Nine male subjects aged 19-25 yr participated in two. 9-h trials (exercise and control) in a random crossover design. Trials began at 0800 in the morning after an overnight fast. In the exercise trial, subjects ran for 60 min at 72% of maximum oxygen uptake between 0800 and 0900. After this, they rested for 8 h and consumed a test meal at 1100. In the control trial, subjects rested for 9 h and consumed a test meal at 1100. Area under the curve values for plasma acylated ghrelin concentration (assessed from venous blood samples) were lower over the first 3 h and the full 9 h of the exercise trial compared with the control trial: 317 +/- 135 vs. 510 +/- 186 pg(.)ml(-1.)3 h and 917 +/- 342 vs. 1,401 +/- 521 pg(.)ml(-1.)9 h (means +/- S E) respectively (P &lt; 0.05). Area under the curve values for hunger (assessed using a visual scale) were lower over the first 3 h of the exercise trial compared with the control trial (P = 0.013). These findings demonstrate that plasma acylated ghrelin concentration and hunger are suppressed during running.

    DOI

  • A single session of treadmill running has no effect on plasma total ghrelin concentrations

    Stephen F. Burns, David R. Broom, Masashi Miyashita, Claire Mundy, David J. Stensel

    JOURNAL OF SPORTS SCIENCES   25 ( 6 ) 635 - 642  2007年04月

     概要を見る

    Ghrelin is a hormone that stimulates hunger. Intense exercise has been shown to temporarily suppress hunger after exercise. In the present study, we investigated whether post-exercise hunger suppression is mediated by reduced plasma total ghrelin concentrations. Nine men and nine women participated in the study. Their mean physical characteristics were as follows: age 24.8 (s(x) = 0.9) years, body mass index 22.9 (s(x) - 0.6) kg center dot m(-2,) maximal oxygen uptake (VO2max) 57.7 (s(x) = 2.2) ml kg(-1) min(-1). The participants completed two 3-h trials (exercise and control) on separate days in a randomized balanced design after overnight fasts. The exercise trial involved a 1-h treadmill run at 73.5% Of VO2max followed by 2 h of rest. The control trial consisted of 3 h of rest. Blood samples were collected at 0, 0.5, 1, 1.5, 2. and 3 h. Total ghrelin concentrations were determined from plasma. Hunger was assessed following blood sampling using a 15-point scale. The data were analysed using repeated-measures analysis of variance. Hunger scores were lower in the exercise trial than in the control trial (trial, P=0.009; time, P &lt; 0.001; trial x time, P &lt; 0.001). Plasma total ghrelin concentrations did not differ between trials. These findings indicate that treadmill running suppresses hunger but this effect is not mediated by changes in plasma total ghrelin concentration.

    DOI

  • A single session of treadmill running has no effect on plasma total ghrelin concentrations

    Stephen F. Burns, David R. Broom, Masashi Miyashita, Claire Mundy, David J. Stensel

    JOURNAL OF SPORTS SCIENCES   25 ( 6 ) 635 - 642  2007年04月  [査読有り]

     概要を見る

    Ghrelin is a hormone that stimulates hunger. Intense exercise has been shown to temporarily suppress hunger after exercise. In the present study, we investigated whether post-exercise hunger suppression is mediated by reduced plasma total ghrelin concentrations. Nine men and nine women participated in the study. Their mean physical characteristics were as follows: age 24.8 (s(x) = 0.9) years, body mass index 22.9 (s(x) - 0.6) kg center dot m(-2,) maximal oxygen uptake (VO2max) 57.7 (s(x) = 2.2) ml kg(-1) min(-1). The participants completed two 3-h trials (exercise and control) on separate days in a randomized balanced design after overnight fasts. The exercise trial involved a 1-h treadmill run at 73.5% Of VO2max followed by 2 h of rest. The control trial consisted of 3 h of rest. Blood samples were collected at 0, 0.5, 1, 1.5, 2. and 3 h. Total ghrelin concentrations were determined from plasma. Hunger was assessed following blood sampling using a 15-point scale. The data were analysed using repeated-measures analysis of variance. Hunger scores were lower in the exercise trial than in the control trial (trial, P=0.009; time, P &lt; 0.001; trial x time, P &lt; 0.001). Plasma total ghrelin concentrations did not differ between trials. These findings indicate that treadmill running suppresses hunger but this effect is not mediated by changes in plasma total ghrelin concentration.

    DOI

  • Multiple bouts of resistance exercise reduce postprandial triacylglycerol concentrations but increase serum C-reactive protein concentrations

    Burns SF, Miyashita M, Ueda C, Stensel DJ

    International Journal of Sport Nutrition and Exercise Metabolism   17 ( 6 ) 556 - 573  2007年

  • Multiple bouts of resistance exercise reduce postprandial triacylglycerol concentrations but increase serum C-reactive protein concentrations

    Burns SF, Miyashita M, Ueda C, Stensel DJ

    International Journal of Sport Nutrition and Exercise Metabolism   17 ( 6 ) 556 - 573  2007年

  • Increased postprandial triacylglycerol concentrations following resistance exercise

    SF Burns, DR Broom, M Miyashita, C Ueda, DJ Stensel

    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE   38 ( 3 ) 527 - 533  2006年03月

     概要を見る

    Purpose: There is conflicting evidence whether a single bout of resistance exercise performed the day before a test meal can lower postprandial triacylglycerol (TAG) concentrations. The present study examined the effect of a single session of resistance exercise, performed the same day as a test meal, on postprandial TAG concentrations in resistance-trained males. Methods: Ten healthy males aged 25 (SD 2.6) yr performed two trials at least 1 wk apart in a counterbalanced, randomized design. In each trial, participants consumed a test meal (0.89 g of fat, 1.23 g of carbohydrate. 0.4 g of protein, 60 kJ center dot kg(-1) body mass). Before one meal, participants performed a 90-min bout of resistance exercise. Before the other meal, participants were inactive (control trial). Resistance exercise was performed using free weights and included three sets of 12 repetitions of each of 10 exercises. Sets were performed at 80% of 12-repetition maximum with a 3-min work and rest interval. Venous blood samples were obtained in the fasted state and for 5 h postprandially. Results: Total area under the plasma TAG concentration versus time curve was higher (Student's t-test P = 0.008) on the exercise than control trial (mean +/- SE: 11.76 +/- 1.64 vs 7.94 +/- 1.08 mmol center dot L-1 center dot 5 h(-1), respectively). Total area under the plasma myoglobin concentration versus time curve was higher (Student's t-test P = 0.010) on the exercise than control trial (16.68 +/- 3.34 vs 6.80 +/- 0.64 nmol center dot L-1 center dot 5 h(-1); respectively). Conclusion: A single bout of resistance exercise can cause a transient elevation in postprandial TAG concentrations. The elevations in plasma myoglobin suggest postexercise muscle damage. Further investigation is needed to see if these findings are linked.

    DOI

  • Increased postprandial triacylglycerol concentrations following resistance exercise

    SF Burns, DR Broom, M Miyashita, C Ueda, DJ Stensel

    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE   38 ( 3 ) 527 - 533  2006年03月  [査読有り]

     概要を見る

    Purpose: There is conflicting evidence whether a single bout of resistance exercise performed the day before a test meal can lower postprandial triacylglycerol (TAG) concentrations. The present study examined the effect of a single session of resistance exercise, performed the same day as a test meal, on postprandial TAG concentrations in resistance-trained males. Methods: Ten healthy males aged 25 (SD 2.6) yr performed two trials at least 1 wk apart in a counterbalanced, randomized design. In each trial, participants consumed a test meal (0.89 g of fat, 1.23 g of carbohydrate. 0.4 g of protein, 60 kJ center dot kg(-1) body mass). Before one meal, participants performed a 90-min bout of resistance exercise. Before the other meal, participants were inactive (control trial). Resistance exercise was performed using free weights and included three sets of 12 repetitions of each of 10 exercises. Sets were performed at 80% of 12-repetition maximum with a 3-min work and rest interval. Venous blood samples were obtained in the fasted state and for 5 h postprandially. Results: Total area under the plasma TAG concentration versus time curve was higher (Student's t-test P = 0.008) on the exercise than control trial (mean +/- SE: 11.76 +/- 1.64 vs 7.94 +/- 1.08 mmol center dot L-1 center dot 5 h(-1), respectively). Total area under the plasma myoglobin concentration versus time curve was higher (Student's t-test P = 0.010) on the exercise than control trial (16.68 +/- 3.34 vs 6.80 +/- 0.64 nmol center dot L-1 center dot 5 h(-1); respectively). Conclusion: A single bout of resistance exercise can cause a transient elevation in postprandial TAG concentrations. The elevations in plasma myoglobin suggest postexercise muscle damage. Further investigation is needed to see if these findings are linked.

    DOI

  • Accumulating short bouts of running exercise throughout the day reduces postprandial plasma triacylglycerol concentrations and resting blood pressure in healthy young men

    Miyashita M, Burns SF, Stensel DJ

    Journal of Physical Activity and Health   3 ( 1 ) 112 - 123  2006年

  • Exercise and postprandial lipemia: effect of continuous versus intermittent activity patterns

    Miyashita M, Burns SF, Stensel DJ

    American Journal of Clinical Nutrition   83 ( 1 ) 24 - 29  2006年

  • Accumulating short bouts of running exercise throughout the day reduces postprandial plasma triacylglycerol concentrations and resting blood pressure in healthy young men

    Miyashita M, Burns SF, Stensel DJ

    Journal of Physical Activity and Health   3 ( 1 ) 111 - 123  2006年

  • Exercise and postprandial lipemia: effect of continuous versus intermittent activity patterns

    Miyashita M, Burns SF, Stensel DJ

    American Journal of Clinical Nutrition   83 ( 1 ) 24 - 29  2006年

  • Accumulating short bouts of running reduces resting blood pressure in young normotensive/prehypertensive men

    Miyashita M, Burns SF, Stensel DJ

    Journal of Sports Sciences   in press

▼全件表示

Works(作品等)

  • 【外部研究費】産学連携共同研究(民間企業1社)

    2014年10月
    -
     

  • 【競争的外部研究費】研究代表者:宮下政司 2014年度 科学研究費補助金 若手研究(B)(1,690,000円)「高齢者における食後中性脂肪に対する身体活動の役割:実験室から日常生活への展開」

    2014年04月
    -
     

  • 【競争的外部研究費(共同研究者)】高橋将記、宮下政司、荒尾孝、内田直、稲山貴代.公益財団法人パブリックヘルスリサーチセンター 2014年度パブリックヘルス科学研究助成金(1,000,000円)「身体不活動が高齢者のメンタルヘルスに及ぼす影響:うつ病バイオマーカーを用いた検討」

    2014年03月
    -
     

  • 【競争的外部研究費】宮下政司(研究代表者:宮下政司)公益財団法人ロッテ財団、平成25年度奨励研究助成(3,000,000円)「運動と食欲に関する研究」

    2013年12月
    -
     

  • 【公募型内部研究費】研究代表者:宮下政司 2013年度トップマネジメント経費 東京学芸大学 (4,066,000円)「スポーツ科学系の教育環境設備」

    2013年07月
    -
     

  • 【競争的外部研究費】研究代表者:宮下政司 2013年度 科学研究費補助金 若手研究(B)(1,430,000円)「高齢者における食後中性脂肪に対する身体活動の役割:実験室から日常生活への展開」

    2013年04月
    -
     

  • 【公募型内部研究費】研究代表者:宮下政司 2012年度トップマネジメント経費 東京学芸大学 (3,062,000円)「スポーツ科学系の教育環境設備」

    2012年07月
    -
     

  • 【競争的外部研究費】研究代表者:宮下政司 2012年度 科学研究費補助金 若手研究(B)(1,430,000円)「高齢者における食後中性脂肪に対する身体活動の役割:実験室から日常生活への展開」

    2012年04月
    -
     

  • 【公募型内部研究費】宮下政司、中村好男、鈴木克彦、朴鍾煥、高橋将記、林田はるみ、川西範明、金賢植.(研究代表者:宮下政司)早稲田大学スポーツ科学学術院 研究推進費(2011-2012年)(2,523,000円)「微小活動が食後中性脂肪濃度に及ぼす影響」

    2011年07月
    -
     

  • 【公募型内部研究費】宮下政司、中村好男、鈴木克彦、朴鍾煥、高橋将記、林田はるみ、川西範明、金賢植.(研究代表者:宮下政司)早稲田大学スポーツ科学学術院 研究推進費(2011-2012年)(1,451,097円)「高齢期の動脈硬化症予防プログラム:ウォーキング実践と抗酸化サプリメント摂取による効果検証」

    2011年07月
    -
     

  • 【公募型内部研究費】宮下政司、中村好男、鈴木克彦、朴鍾煥、高橋将記、林田はるみ、川西範明、金賢植.(研究代表者:宮下政司)早稲田大学スポーツ科学学術院 研究推進費(2011-2012年)(1,620,000円)「高齢者に対するウォーキング介入が動脈硬化指標に及ぼす影響」

    2011年07月
    -
     

  • 【競争的外部研究費】宮下政司、中村好男、鈴木克彦、朴鍾煥、高橋将記(研究代表者:宮下政司)財団法人日本科学協会、2011年度笹川科学研究助成金(600,000円)「微小活動(立位)と食後の脂質代謝:座位中心の生活から身体活動を高める生活へ」

    2011年04月
    -
     

  • 【競争的外部研究費(共同研究者)】河野寛、宮下政司、沼尾成晴、丸藤祐子、坂本静男、樋口満.財団法人 明治安田厚生事業団、健康医科学研究助成 2011年度(第27回)(1,000,000円)「食欲を抑制させる運動様式の探索」

    2011年01月
    -
     

  • 【競争的外部研究費】宮下政司、中村好男、鈴木克彦、林田はるみ.(研究代表者:宮下政司)公益財団法人中冨健康科学振興財団、2011年度研究助成金(1,000,000円)「低体力高齢者における生活習慣改善に向けた有酸素性運動の効果 ~ 新規動脈硬化症予測マーカーに着目して ~」

    2011年01月
    -
     

  • 【競争的外部研究費】宮下政司、中村好男、鈴木克彦、朴鍾煥、高橋将記、林田はるみ.(研究代表者:宮下政司)公益財団法人上原記念生命科学財団、2011年度研究奨励金(2,000,000円)「動脈硬化進展予防に対する運動の役割」

    2010年12月
    -
     

  • 【競争的外部研究費】宮下政司、中村好男、朴鍾煥.(研究代表者:宮下政司)財団法人 慢性疾患・リハビリテイション研究振興財団 平成22年度研究助成(1,000,000円)「動脈硬化進展予防に対する身体活動の役割 ~ 身体活動量と新規動脈硬化症予測マーカーとの関連 ~」

    2010年10月
    -
     

  • 【競争的外部研究費】宮下政司、中村好男、鈴木克彦、林田はるみ、朴鍾煥、高橋将記.(研究代表者:宮下政司)花王株式会社、2011年度(第8回)花王健康科学研究会研究助成(500,000円)「低体力高齢者における生活習慣改善に向けた有酸素性運動の効果 ~新規動脈硬化症予測マーカーに着目して~

    2010年09月
    -
     

  • 【公募型内部研究費】宮下政司、中村好男、朴鍾煥.(研究代表者:宮下政司)早稲田大学スポーツ科学学術院 研究推進費(2010-2011年)(2,095,000円)「身体活動と動脈硬化症予防」

    2010年07月
    -
     

  • 【競争的外部研究費】宮下政司、中村好男、朴鍾煥.(研究代表者:宮下政司)財団法人健康管理事業団、研究助成 2010年度(500,000)「動脈硬化進展予防に対する身体活動の役割 ~ 身体活動量と新規動脈硬化症予測マーカーとの関連 ~」

    2010年07月
    -
     

  • 【競争的外部研究費】宮下政司、中村好男、高泉佳苗.(研究代表者:宮下政司)2010年度(第32回)財団法人石本デサントスポーツ科学振興財団 (500,000円)「有酸素性運動が中性脂肪の日内変動に及ぼす影響:生活活動下における簡易測定器による評価」

    2010年03月
    -
     

  • 【競争的外部研究費】宮下政司、笹井浩行、田中喜代次.(研究代表者:宮下政司)財団法人 ミズノスポーツ復興会、スポーツ学等研究助成 2009年度(第29回)(1,000,000円)「有酸素運動による食後中性脂肪濃度の経時変化:簡易測定器による評価」

    2009年02月
    -
     

  • 【競争的外部研究費】宮下政司、田中喜代次.(研究代表者:宮下政司)財団法人 明治安田厚生事業団、健康医科学研究助成 2008年度(第25回)(1,000,000円)「中・高年低体力者における異なる運動強度による運動が新規脂質・炎症マーカーに及ぼす影響」

    2009年01月
    -
     

  • University of Tsukuba, Graduate School of Comprehensive Human Sciences, Critical Path Research and Education Integrated Leading Center

    2009年
    -
     

  • University of Tsukuba, Graduate School of Comprehensive Human Sciences, Division of Sports Medicine

    2009年
    -
     

  • Nanyang Technological University, Department of Physical Education and Sports Science (Singapore)

    2009年
    -
     

  • 【競争的外部研究費】宮下政司(申請団体:筑波大学).グレイトブリテン・ササカワ財団 医学・健康交流助成 2008年度(500,000円)英国Loughborough大学の Dr David Stenselを招聘

    2008年11月
    -
     

  • 【競争的外部研究費】研究代表者:宮下政司.2007-2009年度 科学研究費補助金 若手研究(スタートアップ)(2,577,000)「生活習慣病者における分散運動が食後高脂血症に及ぼす影響」

    2008年07月
    -
     

  • 【競争的外部研究費】研究代表者:宮下政司.2009-2010年度 科学研究費補助金 若手研究(B)(2,730,000円)「一過性有酸素運動と食後中性脂肪:簡易測定器による検討」

    2008年06月
    -
     

  • 【競争的外部研究費(共同研究者)】中村和照、仙石泰雄、緒形ひとみ、宮下政司、渡部厚一.財団法人上月スポーツ・教育財団 2007年度(第5回)スポーツ研究助成 2008-2009年(500,000円)「フルマラソン走行中の血糖変動がパフォーマンスに与える影響

    2008年01月
    -
     

  • Loughborough University, School of Sport, Exercise and Health Sciences (UK)

    2008年
    -
     

  • 【競争的外部研究費】研究代表者:宮下政司.財団法人冲中記念成人病研究所、研究助成 2008年度(500,000円)「生活習慣病者における一過性中強度運動が食後中性脂肪濃度および血管内皮機能に及ぼす影響」

    2007年12月
    -
     

  • 【競争的外部研究費】研究代表者:宮下政司.財団法人健康管理事業団、研究助成 2007年度(500,000円)「生活習慣病者における一過性の運動が食後中性脂肪濃度に及ぼす影響」

    2007年08月
    -
     

  • 【競争的外部研究費】宮下政司、徳山薫平.(研究代表者:宮下政司)日本オリンピック委員会/日本コカ・コーラ 2007年度スポーツ科学基金(1,000,000円)「分散運動と疲労:抗酸化ビタミンサプリメントの有効性」

    2007年05月
    -
     

  • 【競争的外部研究費】Miyashita M, Stensel DJ. (研究代表者:宮下政司)グレイトブリテン・ササカワ財団、日英共同医学研究、バターフィールド基金 (£3500) “Effects of exercise on gut hormones, appetite and energy intake”

    2007年02月
    -
     

▼全件表示

受賞

  • 2018年度早稲田大学リサーチアワード(国際研究発信力)

    2019年02月   早稲田大学  

    受賞者: 宮下政司

  • Best Paper Award (Oral Presentation)

    2018年08月   2018 The Society of Chinese Scholars on Exercise Physiology and Fitness & 2018 The Society of Taiwan Scholars on Exercise Physiology and Fitness   The effects of masticatory frequency on appetite and energy metabolism assessed by 13C-labelling technique in healthy young men  

    受賞者: Hamada Y, Yanaoka T, Kashiwabara K, Yamamoto R, Suzuki K, Miyashita M

  • 第31回日本体力医学会奨励賞

    2018年08月   日本体力医学会   日本人小・中学生における体力および肥満度と血中脂質性状との関連  

    受賞者: 城所哲宏, 枝元香菜子, 柳岡拓磨, 柏原杏子, 田中英登, 宮下政司

  • 最優秀賞

    2015年06月   ヨーロッパスポーツ科学学会   Associations between various intensities of physical activity and physical fitness in adolescents  

    受賞者: Kidokoro T, Yanaoka T, Kashiwabara K, Yamagami J, Tanaka H, Miyashita M

  • 学会奨励賞

    2014年08月   日本フットボール学会   サッカーの試合における、主審、副審の活動形態と運動強度の違い  

    受賞者: 長谷川雅, 宮下政司

  • 優秀ポスター賞

    2013年03月   日本健康支援学会   玄米飯を主食とした日本型食生活が抗酸化力に及ぼす効果  

    受賞者: 平川和幸, 中村彩希, 秦希久子, 稲山貴代, 宮下政司, 長澤純一, 中田由夫, 岡純, 大河原一憲

  • 2013年度学術奨励賞

    2013年02月   日本体力医学会   Acute effect of increased participation in activities of daily living on postprandial lipaemia in postmenopausal women  

    受賞者: 宮下政司

  • 優秀ポスター賞

    2011年10月   The 2011 International Conference of Exercise for 3Qs   Associations between health-related physical fitness and obesity among 10-18 years Taiwanese students  

    受賞者: Liao Y, Chang S-H, Chen J-F, Wen L-T, Miyashita M, NakamuraY

  • 2010年度学術奨励賞

    2010年02月   日本体力医学会   Thirty minutes of aerobic exercise reduces postprandial capillary triacylglycerol concentrations in centrally obese middle-aged men  

    受賞者: 宮下政司

  • Butterfield Awards for UK-Japan collaboration in medicine and health

    2007年01月   The Great Britain Sasakawa Foundation   Effects of exercise on gut hormones, appetite and energy intake  

    受賞者: 宮下政司

▼全件表示

共同研究・競争的資金等の研究課題

  • 閉経後女性に対する断続性身体活動による食後代謝改善の有用性

    研究期間:

    2017年04月
    -
    2020年03月
     

     概要を見る

    平成29年度に実施した研究は、研究規模上、2年弱をかけて実施する当初通りの計画として、まだ終了していない。しかしながら、当初の計画以上に早いペースで研究を進めており、平成30年の夏ごろを予定にデータ採取については、終える予定で進めている。【背景・目的】当該研究では、閉経後女性を対象に一日を通した身体活動による座位継続時間の中断が食後中性脂肪に及ぼす影響を食事によるエネルギー出納を合わせた条件を用い検討を行っている。身体活動による座位中断が食後の代謝へ及ぼす影響を検討した先行研究では、活動によりエネルギー出納が負となった上で評価をしている(Med Sci Sports Exerc 2015 47:2053-61)。当該研究では、1回あたり1.5分の歩行を1日20 回繰り返す断続性身体活動が、 断続性身体活動中に食事によるエネルギー補充を行う場合と比較し、食後中性脂肪値を同等に抑制させるか否か、閉経後高中性脂肪血症女性及び閉経後女性を対象に比較検討を行っている。【研究デザイン】それぞれの対象ごとに3試行による無作為化交差実験【プロトコル】参加者は、座位安静試行、断続性歩行試行、断続性歩行+食事補充試行の3試行に1週間の間隔を空け参加している。座位安静試行では8時から16 時の間座位安静としている。断続性歩行試行では、1回1.5分、合計30分のトレッドミルでの歩行を9時から16時の間に計20 回実施している。断続性歩行+食事補充試行では、断続性歩行試行に加え計30分で消費したエネルギーを朝食と昼食で補充している。静脈血を空腹時、食後 2、4、6、8 時間に採取している。<BR>今後は、さらに予定している人数(30名)まで例数を増やし、評価項目を中心とした分析や統計解析を進める。計画通りよりも早いペースで実験を進めており、データの採取について問題なく進めることができている。また、学会やシンポジウムの招待演者として得られたデータを平成30年度に発表予定をしており、外部へ研究成果を積極的に発信する。またデータの採取が終わり次第、国際学術誌に論文として投稿するため、準備もしている。平成29年度から30年度に実施している当該報告書の課題を発展させるため、断続性の身体活動(運動・生活活動)が食後中性脂肪に及ぼす影響について、より長期的に検証を行うことで実用化を図る。具体的には、閉経後女性を対象に、対象者を断続性身体活動群、座位行動時間軽減群、連続性身体活動群に無作為に振り分け、3ヶ月の間、日常生活中にそれぞれの活動を「健康づくりための身体活動指針」に則した時間・強度として1日計 10 分以上の自由な活動強度で実施する。身体活動量の増加に伴う他の時間への影響及び食欲への影響の両視点より、日常生活の中で応用可能な具体的な健康支援プログラムの開発のために、科学的知見の創出を目指す

  • ガム咀嚼と運動の組み合わせは食欲を低下させるのか?~効率的な減量法を探る

    公益財団法人ロッテ財団  平成25年度奨励研究助成

    研究期間:

    2014年04月
    -
    2016年03月
     

  • 高齢者における食後中性脂肪に対する身体活動の役割:実験室から日常生活への展開

    研究期間:

    2012年04月
    -
    2015年03月
     

     概要を見る

    研究1より、閉経後女性において週末の身体活動量を増やすことで食後の中性脂肪値が低減することを明らかにした。研究2より、閉経後女性において1日の身体活動量を継続して4週間増やした結果、食後の中性脂肪値に影響を与えないことを明らかにした。研究3より、閉経後女性において短時間の歩行を断続的に実施することで食後の中性脂肪値の上昇を抑制することを明らかにした。得られたデータは、いかに低・中等度の活動を頻繁に繰り返すことや座位時間を短くするために短時間の活動を取り入れることが心血管疾患の危険要因である食後高中性脂肪血症の予防に有効であることを支持する結果である

  • 食欲減衰のための縄跳び運動の可能性

    研究期間:

    2011年04月
    -
    2013年03月
     

     概要を見る

    本研究は、縄跳びのような重心の上下動を伴う運動は、一過性の運動による食欲の低下を効率的に引き起こすだけでなく、重心の上下動を伴わない運動と比較して、運動由来の食欲低下にグレリンやペプチドYY などの食欲関連ホルモンの貢献度がそれほど大きくないことを明らかにした。加えて、一過性の運動後の食欲は、男性と比較して女性で速やかに亢進(回復)することがわかった。これらの結果は、性別を考慮した肥満の予防・改善のための運動処方作成におけるエビデンスの一つになるだろう

  • 生活習慣病者における分散運動が食後高脂血症に及ぼす影響

     概要を見る

    背景と目的:生活習慣病の予防を意図した身体活動に関する健康づくり指針は、一日30分以上の中強度の身体活動をできれば毎日実施する事を推奨している。またできれば毎日、一回10分以上の身体活動を一日通し計30分以上中強度で行う事も推奨している。しかし、健康に対する一回10分未満の短時間の身体活動の実質効果を調べた研究は不足している。本研究では、生活習慣病者を対象に心臓血管病の危険因子である食後の中性脂肪について、中強度で3分10回と30分1回の自転車漕ぎ運動が食後の中性脂肪値に及ぼす影響を比較した。対象・方法:8名の男性肥満者(27±2歳)は連続した2日間の工程を1週間の間隔を空け3試行に参加した。実験一日目、安静試行では参加者は運動を行わず安静を保ち、運動試行では最大心拍数の60%の強度で自動車漕ぎを3分、1日を通し10回(30分の休憩をはさみながら)、または30分1回の自転車漕ぎ運動を行った。各試行とも実験2日目、参加者は10時間の空腹の後、中脂肪食を朝食に取り、その後安静を6時間保った。血液を実験2日目の空腹時、食後2時間後、4時間後、6時間後に採取した。結果:実験2日目の食後の中性脂肪値は安静試行と比較し、分散運動試行、一過性運動試行でそれぞれ有意に低値を示した。両運動試行の間には有意な差は認められなかった。結論:男性の肥満者において、一日を通し一回あたり短時間の累積した30分の分散運動は30分の一過性運動と同程度、食後の中性脂肪値を低減することを明らかにした。従って、長時間運動が行うことができない人においても、一回あたり短時間の累積した運動は生活習慣病予防の観点で有効である

  • 一過性有酸素運動と食後中性脂肪:簡易測定器による評価

     概要を見る

    研究1より、中年の肥満男性において、身体活動指針が推奨する最低限の運動量での一過性の30分の自転車漕ぎ運動は、食後毛細血管中性脂肪濃度を低減させることを明らかにした。この結果より、運動を定期的に行い習慣となれば、心血管疾患の予防のための運動療法となり得ることを示唆した。研究2より、食後毛細血管中性脂肪濃度は、非活動群と比較し、活動群で低値を示した。この結果より、急性的な身体活動による影響とは区別した習慣的な身体活動による食後中性脂肪の低減効果を明らかにした

▼全件表示

講演・口頭発表等

  • 運動療法ガイドライン策定に向けた取り組み

    宮下政司

    第74回日本体力医学会大会   (茨城)  日本体力医学会  

    発表年月: 2019年09月

  • 運動と食欲

    宮下政司  [招待有り]

    日本スポーツ栄養学会第6回大会   (東京)  日本スポーツ栄養学会  

    発表年月: 2019年08月

  • Physical activity for older adults – Implication for postprandial triacylglycerol metabolism (Invited talk)

    宮下政司  [招待有り]

    2018 The Society of Chinese Scholars on Exercise Physiology and Fitness & 2018 The Society of Taiwan Scholars on Exercise Physiology and Fitness   (台中) 

    発表年月: 2018年08月

  • Effect of tea catechin-rich beverage intake on exercise performance (Invited talk)

    宮下政司  [招待有り]

    The 8th International Conference on Sports and Exercise Science   (バンコク)  Chulalongkorn University  

    発表年月: 2018年06月

  • Impact of physical activity and physical inactivity on postprandial metabolism in older adults (Invited talk)

    宮下政司  [招待有り]

    2018 Food, Exercise and Technology for Health Promotion   (シンガポール)  Waseda University  

    発表年月: 2018年01月

  • Physical activity and postprandial lipid metabolism; implications for everyday life (Invited talk)

    宮下政司  [招待有り]

    14th National Kasetsart University Kamphaeng Sean Conference   (Kamphaeng Sean)  Kasetsart University  

    発表年月: 2017年12月

  • 定期的な身体活動による脂質代謝の改善(招待講演)

    宮下政司  [招待有り]

    第17回日本抗加齢医学会総会   (東京)  日本抗加齢医学会  

    発表年月: 2017年06月

  • 身体活動・身体不活動を科学する:よりよい健康づくりのために(招待講演)

    宮下政司  [招待有り]

    日本農芸化学会2017年度大会   (京都)  日本農芸化学会  

    発表年月: 2017年03月

  • 身体活動の増加による高齢期の動脈硬化症に対する予防策(招待講演)

    宮下政司  [招待有り]

    日本女子体育大学 基礎体力研究所 第27回公開研究フォーラム   (東京)  日本女子体育大学 基礎体力研究所  

    発表年月: 2016年12月

  • 身体活動の増加による生活習慣病の予防・改善:空腹時及び食後の糖・脂質代謝の視点から(招待講演)

    宮下政司  [招待有り]

    第34回東北理学療法学術大会   (秋田)  秋田県理学療法士会  

    発表年月: 2016年11月

  • 運動療法による脂質代謝の改善(招待講演)

    宮下政司  [招待有り]

    第35回日本臨床運動療法学会学術集会   (神奈川)  日本臨床運動療法学会  

    発表年月: 2016年09月

  • 座位時間の中断を意図した断続性身体活動による食後代謝改善の有用性(招待講演)

    宮下政司  [招待有り]

    第48回日本動脈硬化学会総会・学術集会   (東京)  日本動脈硬化学会  

    発表年月: 2016年07月

  • Interrupting prolonged sitting time with short walks attenuates postprandial lipaemia in postmenopausal women (Invited talk)

    宮下政司  [招待有り]

    2015 Winter International Conference and Workshop for Korean Society of Exercise Physiology   (韓国)  Korean Society of Exercise Physiology  

    発表年月: 2015年12月

  • Acute and chronic effects of increased physical activity on postprandial triglyceride metabolism in postmenopausal women (Invited talk)

    宮下政司  [招待有り]

    28th International University Sports Federation and 88 Seoul Olympic Commemoration Conferences   (韓国)  International University Sports Federation  

    発表年月: 2015年07月

  • 食後中性脂肪に対する身体活動の有用性:運動・生活活動による効果検証(招待講演)

    宮下政司  [招待有り]

    第18回日本病態栄養学会   (京都)  日本病態栄養学会  

    発表年月: 2015年01月

  • Acute effect of increased participation in activities of daily living on postprandial lipaemia in postmenopausal women (Invited talk)

    宮下政司  [招待有り]

    The 68th European College of Sport Science Annual Congress   (スペイン)  European College of Sport Science  

    発表年月: 2013年06月

  • Thirty minutes of aerobic exercise reduces postprandial capillary triacylglycerol concentrations in centrally obese middle-aged men (Invited talk)

    宮下政司  [招待有り]

    The 16th European College of Sport Science Annual Congress   (トルコ)  European College of Sport Science Annual Congress  

    発表年月: 2013年06月

  • Physiological benefits of low volume of physical activity in older adults (Invited talk)

    宮下政司  [招待有り]

    2013 International Symposium on Physical Activity and Exercise Science   (台湾)  National Chung Hsing University  

    発表年月: 2013年05月

  • 脂質異常症の予防のための運動・生活活動を科学する(招待講演)

    宮下政司  [招待有り]

    第25回ランニング学会   (東京)  ランニング学会  

    発表年月: 2013年03月

  • 動脈硬化症の予防を目的とした日常生活中の活動量を高めるための工夫(招待講演)

    宮下政司  [招待有り]

    第156回日本体力医学会関東地方会   (東京)  日本体力医学会  

    発表年月: 2012年12月

  • 身体活動と脂質異常症予防 (招待講演)

    宮下政司  [招待有り]

    動脈硬化Update 2012   (東京)  日本動脈硬化学会  

    発表年月: 2012年09月

  • The role of physical activity in the prevention of atherosclerotic cardiovascular disease in older adults (Invited talk)

    宮下政司  [招待有り]

    2011 International Conference of Korean Society of Exercise Physiology   (韓国)  Korean Society of Exercise Physiology  

    発表年月: 2011年11月

  • Exercise in the prevention of cardiovascular disease: the health benefits of accumulating exercise (Invited talk)

    宮下政司  [招待有り]

    The 2011 International Conference of Exercise for 3Qs - Health Quotient, Emotion Quotient and Intelligence Quotient   (台湾)  National Taiwan Sport University  

    発表年月: 2011年10月

  • 高強度運動と低強度運動の有効性(招待講演)

    宮下政司  [招待有り]

    第12回日本健康支援学会プレカンファレンス健康に関わるディベート   (福岡)  日本健康支援学会  

    発表年月: 2011年02月

  • Physical activity and health promotion: Research directions and methods (Invited talk)

    宮下政司  [招待有り]

    2011 The International Council for Health, Physical Education, Recreation, Sport, and Dance (ICHPER‧SD) Asia Congress   (台湾)  The International Council for Health, Physical Education, Recreation, Sport, and Dance  

    発表年月: 2011年01月

  • Physical activity and postprandial lipaemia: Implications for active living (Invited talk)

    宮下政司  [招待有り]

    10th Anniversary International Symposium on Human and Sports Science   (韓国)  Keimyung University  

    発表年月: 2010年12月

  • 有酸素性運動と非空腹時(食後)中性脂肪:基礎から応用への展開(招待講演)

    宮下政司  [招待有り]

    第61回日本体育学会運動生理学   (愛知)  日本体育学会  

    発表年月: 2010年09月

  • Aerobic exercise and non-fasting triacylglycerol: translating theory into practice (Invited talk)

    宮下政司  [招待有り]

    Dong-A University Seminar   (韓国)  Dong-A University  

    発表年月: 2010年08月

  • 生活習慣とLPL:運動、減量との関連(招待講演)

    宮下政司  [招待有り]

    第10回LPL研究会   (東京)  LPL研究会  

    発表年月: 2010年04月

  • 生活指導の立場から〜肥満に対する運動と食事療法の寄与度について〜(招待講演)

    宮下政司  [招待有り]

    第20回日本臨床スポーツ医学会   (兵庫)  日本臨床スポーツ医学会  

    発表年月: 2009年11月

  • 運動療法が肥満者の脂質プロファイルに及ぼす影響(招待講演)

    宮下政司  [招待有り]

    福岡大学スポーツ科学部セミナー   (福岡)  福岡大学  

    発表年月: 2009年09月

  • 有酸素性運動による脂質代謝異常の改善(招待講演)

    宮下政司  [招待有り]

    第17回日本運動生理学会   (東京)  日本運動生理学会  

    発表年月: 2009年07月

  • 分割運動による食後中性脂肪の上昇抑制効果(招待講演)

    宮下政司  [招待有り]

    第10回日本健康支援学会   (福岡)  日本健康支援学会  

    発表年月: 2009年02月

▼全件表示

学内研究費(特定課題)

  • 食欲の評価法における日本語版の開発および妥当性の検討

    2021年  

     概要を見る

    The present study aimed to develop a Japanese version of the LFPQ (LFPQ-J); examineits outcomes under fasted and fed states; and test its reproducability afterone week. An online survey containing foodsthat were either low-fat sweet, high-fat sweet, low-fat savoury or high-fatsavoury was first conducted among a sample of 200 Japanese adults (100 men and100 women) to develop and validate a culturally appropriate food imagedatabase. Sixty participants (30 men and 30 women) then participated in two identicaltrials where they completed the LFPQ-J under fasted and fed states (immediatelyafter a standardised meal), at least one week apart. The absolute differencewithin the participants in scores for explicit liking, explicit wanting,implicit wanting and relative preference between the trials was analysed usingBland-Altman plots and Pearson’s or Spearman’s correlation coefficients. The present study demonstrates that the LFPQ-J is a sensitive and reproducible instrumentfor the evaluation of liking and wanting for food varying in fat content andsweet taste in Japanese adults.

  • 上肢及び下肢運動が運動時のエネルギー代謝応答と食後の血中代謝応答に及ぼす影響

    2020年  

     概要を見る

    This study aimed toinvestigate the effects of a single bout of upper or lower body exercise onpostprandial triglyceride (TG) concentrations in healthy young men. Ninehealthy young men (aged 22 ± 2, body mass index 22 ± 2, mean ± SD ) underwentthree, 8-h experimental trials with at least a 7-day washout period: 1) control(C), 2) upper-body exercise (U) and 3) lower-body exercise (L). On the C trial,participants sat in a chair for 8 h. For the exercise trials, participantsperformed one 30-min bout of upper-body or lower-body exercise in the morning(0900-0930 h). Except for exercise, both exercise trials mimicked the controltrial. In each trial, participants consumed a standardised breakfast (1000 h)and lunch (1300 h). Blood samples were collected in the fasted state,immediately after exercise or rest (0.5 h), and at 2, 4, 6, and 8 h after thecommencement of each trial. Serum TG concentrations differed among trials andwere higher in the U trial than L and C trials. The present study demonstratesthat an acute bout of upper-body exercise increases postprandial TGconcentrations, partly due to a transient insulin resistance by thephysiological stress of unfamiliar exercise.

  • 閉経後女性における3ケ月間の断続性身体活動が食後中性脂肪に及ぼす影響

    2019年  

     概要を見る

    This studywas to examine the chronic effect of increased physical activity of dailyliving on postprandial triacylglycerol (TAG) in postmenopausal women. Twentysixpostmenopausal women, aged 72 ± 5 years (mean ± SD), were randomly divided intotwo groups: active (n=11) and control (n=15) groups. The participants in theactive group were asked to increase their activities above their usuallifestyle levels &nbsp;for 3 months; freely deciding the duration andintensity of their chosen activities (i.e.,at least 10 minutes per day). The participants in thecontrol group maintained their usual lifestyle for 3 months. All participantswere asked to wear a uniaxial accelerometer for 3 consecutive months. Atbaseline, after 1 month and after 3 months, all participants rested andconsumed a standardised breakfast after a 24-hour period of physical activityavoidance. Blood samples were collected in the fasted state (0 hour) and at 2,4 and 6 hours after breakfast. There was no difference in the pattern ofpostprandial TAG response between groups. Postprandial TAG was not reducedafter performing self-selected activities under free-living in postmenopausalwomen when these responses aredetermined 24 hours after the last physical activity bout.

  • 閉経後女性における断続性歩行が食後中性脂肪に及ぼす影響:エネルギー補充との比較

    2018年  

     概要を見る

    Purpose: The present study examined the effect of multiple short bouts of exercise, with and without dietary replacement of the exercise-induced energy deficit, on postprandial TG in older women. Methods: Seventeen postmenopausal women underwent three, 8-hour laboratory-based trials in a random order: 1) control, 2) accumulated walking and 3) accumulated walking with energy replacement. During the control trial, participants rested for 8 hours. The accumulated walking trial comprised twenty 1.5 min bouts of brisk walking performed at a pre-determined self-selected pace with 15 min seated rest between walks. In each trial, participants consumed a standardised breakfast (0800, 0 h) and lunch (1100, 3 h). The breakfast in the accumulated walking with energy replacement trial included replacement of the same energy deficit induced by exercise. Venous blood samples were collected fasted and at 2, 4, 6 and 8 h after breakfast. Results: Time-averaged postprandial serum TG concentrations over 8 hours were lower after accumulated walking than control and accumulated walking with energy replacement. There was little difference between control and accumulated walking with energy replacement. Conclusions: Replacing the energy expenditure induced by accumulating 30 min of brisk walking in short (1.5 min) bouts diminishes the postprandial TG-lowering effect in postmenopausal women.

  • 胃の拡張がグレリンの分泌動態に及ぼす影響

    2016年  

     概要を見る

    若年男性を対象に、異なる量の2つの飲料(①低質量試行②高質量試行)摂取後の消化管の動態を調べるために超音波診断装置を用いて胃幽門部断面積の計測をおこなった。その結果、胃幽門部断面積は高質量試行において低質量試行と比較して有意に高い値を示した。また、主観的な満腹感は高質量試行において上昇し、甘味・塩味への欲求は減少したものの、自由摂取の食事量調査におけるエネルギー摂取量は高質量試行において有意に高い値を示した。2時間中の胃収縮回数は高質量試行にて有意に高い値を示した。血糖、中性脂肪、遊離脂肪酸においては試行間に差は見られなかった。本研究より高質量の飲水後は、低質量の飲水後と比較して胃幽門部断面積が増加し、一時的に主観的な食欲が低下することが明らかとなった。しかし、高質量の飲水後は胃収縮回数が増加し、飲水2時間後のエネルギー摂取量の増加に繋がる可能性が示唆された。

  • 閉経後脂質異常症・2型糖尿病女性に対する断続性身体活動による食後代謝改善の有用性

    2016年   鈴木克彦

     概要を見る

    Purpose: Although a single bout of continuous exercise (≥30 min) reduces postprandial triglyceride (TG), little evidence is available regarding the effect of short (≤10 min) bouts of exercise on postprandial TG in at-risk individuals. This study compared the effect of different patterns of walking on postprandial TG in older women with hypertriglyceridemia. Methods: Twelve older women (aged 71 ± 5 yrs, mean ± S.D.) with hypertriglyceridemia (fasting TG ≥ 1.70 mmol/L) completed three, one-day trials in a random order: 1) control, 2) continuous walking, and 3) short bouts of walking. On the control trial, participants rested for 8 hours. For the walking trials, participants walked briskly in either one 30-min bout in the morning (0900-0930) or twenty 90-sec bouts over 8 hours. Venous blood samples were collected in the fasted state and at 2, 4, 6 and 8 h after breakfast. Results: The serum TG incremental area under the curve was 35% and 33% lower on the continuous and short bouts of walking trials than the control trial (8.2 ± 3.1 vs 8.5 ± 5.4 vs 12.7 ± 5.8 mmol∙8h/L respectively, P = 0.001). Conclusions: Accumulating walking in short bouts limits postprandial TG in at-risk, older women with fasting hypertriglyceridemia.

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現在担当している科目

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委員歴

  • 2018年07月
    -
     

    東京都港区部活動の在り方検討委員会  委員長

  • 2016年07月
    -
     

    Japan Sports Nutrition Association  International Committee

  • 2016年07月
    -
     

    日本スポーツ栄養学会  国際交流委員会

  • 2015年09月
    -
     

    Japanese Society of Physical Fitness and Sports Medicine  Programme Committee

  • 2015年09月
    -
     

    日本体力医学会  プログラム委員会

  • 2015年09月
    -
     

    Japanese Society of Physical Fitness and Sports Medicine  Editorial Committee

  • 2015年09月
    -
     

    日本体力医学会  編集委員会

  • 2015年04月
    -
     

    Japan Society of Health Promotion  Fellow

  • 2015年04月
    -
     

    日本健康支援学会  評議員

  • 2013年09月
    -
    2015年03月

    Japanese Society of Physical Fitness and Sports Medicine  Conflict of Interest Committee

  • 2013年09月
    -
    2015年03月

    日本体力医学会  利益相反委員会委員

  • 2015年01月
    -
     

    Korean Society of Exercise Physiology  An international board director

  • 2015年01月
    -
     

    韓国運動生理学会  評議員

  • 2014年09月
    -
     

    Japanese Society of Physical Fitness and Sports Medicine  International Committee

  • 2014年09月
    -
     

    日本体力医学会  渉外委員会委員

  • 2011年09月
    -
     

    Japanese Society of Physical Fitness and Sports Medicine  Fellow

  • 2011年09月
    -
     

    日本体力医学会  評議員

▼全件表示

社会貢献活動

  • 「生活活動の増加によるメタボリックシンドロームに対する予防・改善策」講師

    日本栄養士会  メタボリックシンドローム予防のための健康セミナー  (長野) 

    2016年11月
     
     

  • 「運動や抗酸化物質が酸化ストレス指標に及ぼす影響」講師

    株式会社ウィスマー  第3回スポーツと酸化ストレス・抗酸化ストレスセミナー  (東京) 

    2016年10月
     
     

  • 「子どもたちの身体活動実施の現状」講師

    長野県佐久市立平根小学校学校保健委員会  長野県佐久市立平根小学校学校保健委員会  (長野) 

    2016年08月
     
     

  • 「断続性身体活動による食後中性脂肪値への影響:運動介入から生活活動介入まで」講師

    株式会社ロッテ  講演会  (埼玉) 

    2016年01月
     
     

  • 「生活習慣介入が酸化ストレス指標に及ぼす影響」講師

    株式会社ウィスマー  第2回スポーツと酸化ストレス・抗酸化ストレスセミナー  (東京) 

    2015年11月
     
     

  • 「子どもの健康と体力」講師

    長野県佐久市東中学校区三校合同PTA研究集会  講演会  (長野) 

    2015年11月
     
     

  • 「グラウンド・ゴルフ指導(スポーツ指導)の基礎知識Ⅰ」講師

    公益社団法人日本グラウンド・ゴルフ協会  平成27年度近畿ブロック2級普及指導員養成講習会  (兵庫) 

    2015年05月
     
     

  • 「生活習慣と子どもの健康」講師

    長野県佐久市  長野県佐久市保健事業講習  (長野) 

    2014年09月
     
     

  • 「科学的根拠に基づく健康づくりの考え方と実践」講師

    文部科学省  平成26年度免許状更新講習  (東京) 

    2014年08月
     
     

  • 「今より少しでも多く!生活の中で増やす身体活動量」講師

    日本動脈硬化学会  第46回日本動脈硬化学会総会・学術集会 市民公開講座「健康寿命を延ばすために! 今日からスタート!心臓病と脳卒中の予防と対策」  (東京) 

    2014年07月
     
     

  • 「健康づくりとしての運動・生活活動を科学する」講師

    東京学芸大学附属学校研究会保健体育部会  講演会  (東京) 

    2014年05月
     
     

  • 「科学的根拠に基づく健康づくりの考え方と実践」講師

    文部科学省  平成25年度免許状更新講習  (東京) 

    2013年08月
     
     

  • 「アスリートに必要な体力と食生活」講師

    社団法人日本プロボウリング協会  2013年専門講習会 Part 1  (東京) 

    2013年08月
     
     

  • 「健康づくりの考え方と実践:運動・生活活動を科学する」講師

    花王株式会社  講演会  (東京) 

    2013年08月
     
     

  • 「代謝性疾患予防のための運動~食前の運動による健康効果を中心に~ およびウォーキングの実技指導」講師

    茨城県立健康プラザ  平成21年度健康づくり指導者研究会第二期  (茨城) 

    2009年10月
     
     

  • 「代謝性疾患予防のための運動~食後の運動による健康効果を中心に~」

    茨城県立健康プラザ  平成21年度健康づくり指導者研究会第二期  (茨城) 

    2009年09月
     
     

  • 「代謝性疾患予防のための運動~食前の運動による健康効果を中心に~ およびウォーキングの実技指導」講師

    茨城県立健康プラザ  平成21年度健康づくり指導者研究会第一期  (茨城) 

    2009年08月
     
     

▼全件表示

メディア報道

  • 調査委員会特別委員

    公益社団法人日本グラウンド・ゴルフ協会  

    東京  

    2014年12月