坂本 静男 (サカモト シズオ)

写真a

所属

スポーツ科学学術院

職名

名誉教授

学歴 【 表示 / 非表示

  •  
    -
    1976年

    弘前大学   医学部   医学  

学位 【 表示 / 非表示

  • 聖マリアンナ医科大学   医学博士

経歴 【 表示 / 非表示

  • 2004年
    -
    2019年03月

    東京女子医科大学第2病院内科客員教授

  • 2003年
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    2018年03月

    順天堂大学医学部循環器内科客員教授

  • 1994年04月
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    2003年03月

    順天堂大学医学部付属浦安病院   健康・スポーツ診療科   講師

  • 2003年
    -
     

    早稲田大学スポーツ科学部 教授

  • 1991年04月
    -
    1994年03月

    国際武道大学 教授

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所属学協会 【 表示 / 非表示

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    日本産業衛生学会

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    日本体育学会

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    日本心電学会

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    日本内科学会

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    日本糖尿病学会

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研究分野 【 表示 / 非表示

  • 衛生学、公衆衛生学分野:実験系を含まない

  • 衛生学、公衆衛生学分野:実験系を含む

  • 衛生学、公衆衛生学分野:実験系を含まない

  • 衛生学、公衆衛生学分野:実験系を含む

  • 循環器内科学

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研究キーワード 【 表示 / 非表示

  • スポーツ医学,循環器内科学、運動処方と運動療法、ヘルスプロモーション、心臓病態学、健康管理、成人保健、スポーツのためのメディカルチェック、スポーツ選手のコンディショニング

論文 【 表示 / 非表示

  • Visceral fat and cardiorespiratory fitness with prevalence of pre-diabetes/diabetes mellitus among middle-aged and elderly Japanese people: WASEDA'S Health Study

    Chiyoko Usui, Ryoko Kawakami, Kumpei Tanisawa, Tomoko Ito, Hiroki Tabata, Satoshi Iizuka, Takuji Kawamura, Taishi Midorikawa, Susumu S. Sawada, Suguru Torii, Shizuo Sakamoto, Katsuhiko Suzuki, Kaori Ishii, Koichiro Oka, Isao Muraoka, Mitsuru Higuchi

    PLOS ONE   15 ( 10 ) e0241018  2020年10月  [査読有り]  [国際誌]

    担当区分:責任著者

     概要を見る

    The relationships between cardiorespiratory fitness (CRF) measurements not confounded by adiposity and the prevalence of pre-diabetes mellitus (pre-DM) and diabetes mellitus (DM) are not well known. Thus, we aimed to investigate the associations of visceral fat (VF) and CRF with the prevalence of pre-DM/DM among Japanese adults. The study included 970 individuals (327 women and 643 men) who were 40-87 years old and had complete health examinations, abdominal fat area, and fitness data from WASEDA'S Health Study during 2015-2018. The VF area was measured using magnetic resonance imaging. CRF was measured using a cycle ergometer and was defined as VO2peak divided by fat free mass. The pre-DM/DM was identified based on the questionnaire and fasting blood tests. The odds ratios (ORs) and 95% confidence intervals (CIs) for prevalence of pre-DM/DM were calculated. Seventy-three participants had pre-DM and 48 participants had DM. Compared to the low VF group, the high VF group had a higher prevalence of pre-DM/DM (OR: 1.87, 95% CI: 1.18-2.96), although no significant relationship was observed between CRF and pre-DM/DM prevalence (P for trend = 0.239). The sub-group analyses also revealed no significant relationship between CRF and pre-DM/DM prevalence in the low VF group (P for trend = 0.979), although CRF values were inversely related to the prevalence of pre-DM/DM in the high VF group (P for trend = 0.024). Although CRF was not independently related to the prevalence of pre-DM/DM after adjusting for adiposity, higher VF values were related to a higher prevalence of pre-DM/DM. In addition, CRF levels were inversely associated with the prevalence of pre-DM/DM only among high VF individuals.

    DOI PubMed

  • The Relationship between Changes in Organ-Tissue Mass and Sleeping Energy Expenditure Following Weight Change in College Sumo Wrestlers

    Taishi Midorikawa, Shigeho Tanaka, Takafumi Ando, Masayuki Konishi, Megumi Ohta, Suguru Torii, Shizuo Sakamoto

    Medicina   56 ( 10 ) 536 - 536  2020年10月  [査読有り]

    担当区分:最終著者

     概要を見る

    Background and objectives: It has been well established that the resting energy expenditure (REE) for the whole body is the sum of the REE for each organ-tissue in young and middle-aged healthy adults. Based on these previous studies, although it is speculated that sleeping energy expenditure (SEE, which has small inter-individual variability) changes with a commensurate gain or reduction in the resting metabolic rate of each organ-tissue, it is unclear whether a change in organ-tissue masses is directly attributed to the fluctuation of SEE at present. This study aimed to assess the relationship between changes in organ-tissue mass and sleeping energy expenditure (SEE) following weight change in college Sumo wrestlers. This included blood analysis, which is related to energy expenditure. Materials and Methods: A total of 16 healthy male college Sumo wrestlers were recruited in this study. All measurements were obtained before and after weight change. Magnetic resonance imaging measurements were used to determine the volume of the skeletal muscle (SM), liver, and kidneys, and an indirect human calorimeter was used to determine SEE before and after weight change. Results: The change in body mass and SEE ranged between −8.7~9.5 kg, and −602~388 kcal/day. Moreover, changes in SM, liver, and kidneys ranged between −3.3~3.6 kg, −0.90~0.77 kg, and −0.12~0.07 kg. The change in SEE was not significantly correlated with the change in SM or liver mass, nor with blood analyses; however, a significant relationship between the change in kidney mass and SEE was observed. Conclusions: Based on our results, there is a possibility that the mass of the kidneys has an effect on the change in SEE following weight change in college Sumo wrestlers.

    DOI

  • Cut-offs for calf circumference as a screening tool for low muscle mass: WASEDA'S Health Study.

    Ryoko Kawakami, Motohiko Miyachi, Susumu S Sawada, Suguru Torii, Taishi Midorikawa, Kumpei Tanisawa, Tomoko Ito, Chiyoko Usui, Kaori Ishii, Katsuhiko Suzuki, Shizuo Sakamoto, Mitsuru Higuchi, Isao Muraoka, Koichiro Oka

    Geriatrics & gerontology international   20 ( 10 ) 943 - 950  2020年10月  [国内誌]

     概要を見る

    AIM: To re-evaluate the suitability of calf circumference as a surrogate marker of low muscle mass measured by both bioelectrical impedance analysis (BIA) and dual-energy X-ray absorptiometry (DXA). We also examined the effects of obesity and age on low muscle mass screening using calf circumference. METHODS: In total, 1239 adults participated in this cross-sectional study. We measured the maximum calf circumference in a standing position and appendicular skeletal muscle mass (ASM) using BIA and DXA. We defined low muscle mass based on the Asian Working Group for Sarcopenia 2019 consensus. RESULTS: Calf circumference was positively correlated with BIA-measured ASM/height2 (men: r = 0.81, women: r = 0.73) and DXA-measured ASM/height2 (men: r = 0.78, women: r = 0.76). In the subgroup analyses by obesity and age, calf circumference was also positively correlated with ASM/height2 . The optimal calf circumference cut-offs for low muscle mass screening measured by BIA and DXA were 35 cm (sensitivity 91%, specificity 84%) and 36 cm (sensitivity 82%, specificity 80%) for men, and 33 cm (sensitivity 82%, specificity 84%) and 34 cm (sensitivity 85%, specificity 72%) for women, respectively. CONCLUSIONS: Calf circumference is positively correlated with BIA- and DXA-measured muscle mass regardless of obesity and age and is a simple and accurate surrogate marker of muscle mass for diagnosing sarcopenia. Geriatr Gerontol Int 2020; 20: 943-950.

    DOI PubMed

  • 高血圧症に対する運動処方

    坂本静男

    Hypertension Research   43 ( 3 ) 155 - 161  2020年03月  [査読有り]  [国際誌]

    担当区分:筆頭著者

    DOI

  • Skeletal muscle deoxygenation and its relationship to aerobic capacity during early and late stage of aging

    Takagi S, Kime R, Murase N, Niwayama M, Sakamoto S, Katsumura T

        in press  2020年  [査読有り]

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書籍等出版物 【 表示 / 非表示

  • スポーツ医学【内科】—はじめて学ぶ 健康・スポーツ科学シリーズ(共著)

    坂本静男

    化学同人  2014年03月 ISBN: 9784759817058

  • 健康運動指導士養成講習会テキスト上・下(共著)

    坂本静男

    公益財団法人 健康・体力づくり事業財団  2014年03月

  • 健康・スポーツ科学テキスト−トレーニング科学(共著)

    坂本静男

    文光堂  2011年11月

  • メタボリックシンドロームに効果的な運動・スポーツ(編著)

    坂本静男

    ナップ社  2011年11月

  • ローイングの健康スポーツ科学(共著) 中高年ローイング愛好者の健康管理−メディカルチェック

    坂本静男

    市村出版  2011年09月

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Misc 【 表示 / 非表示

  • Parasympathetic Nervous Regulation and Prevalence of Lifestyle-related Diseases In Japanese: Waseda's Health Study

    Masayuki Konishi, Susumu S. Sawada, Ryoko Kawakami, Kumpei Tanisawa, Hiroki Tabata, Nobuhiro Nakamura, Hyeon-Ki Kim, Tomoko Ito, Mitsuru Higuchi, Katsuhiko Suzuki, Suguru Torii, I-Min Lee, Steven N. Blair, Koichiro Oka, Shizuo Sakamoto

    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE   51 ( 6 ) 216 - 216  2019年06月

    研究発表ペーパー・要旨(国際会議)  

    DOI

  • Cardiorespiratory Fitness and Prevalence of Lifestyle-related Diseases In Japanese Men And Women: WASEDA'S Health Study

    Susumu S. Sawada, Ryoko Kawakami, Kumpei Tanisawa, Hiroki Tabata, Nobuhiro Nakamura, Kim Hyeon-Ki, Masayuki Konishi, Tomoko Ito, Chiyoko Usui, Taishi Midorikawa, Mitsuru Higuchi, Katsuhiko Suzuki, Suguru Torii, Lee I-Min, Steven N. Blair, Isao Muraoka, Kaori Ishii, Koichiro Oka, Shizuo Sakamoto

    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE   51 ( 6 ) 218 - 219  2019年06月

    研究発表ペーパー・要旨(国際会議)  

    DOI

  • 平成30年度日本スポーツ協会スポーツ医・科学専門委員会IV 東京オリンピック記念体力測定の総括-第1報- (第9章)1964年東京オリンピック大会参加選手の全身持久力と高血圧罹患 コホート研究

    澤田 亨, 川上 諒子, 岡 浩一朗, 坂本 静男, 岡田 純一, 樋口 満, 長阪 裕子, 青野 博, 石塚 創也, 山田 早智子, 川原 貴

    日本スポーツ協会スポーツ医・科学研究報告集   2018年度   63 - 66  2019年03月

  • 日本人の食前血中遊離脂肪酸は食後糖代謝と関連する

    沼尾成晴, 河野寛, 遠藤直哉, 山田優香, 高橋将記, 小西真幸, 坂本静男

    京薬論集   23   23 - 36  2017年03月

    記事・総説・解説・論説等(大学・研究所紀要)  

  • 皮膚温の2°C低下に着目した生理・生化学的な検討 -実験室および現地調査の報告-

    小西真幸, 坂本静男

    体力科学   66 ( 1 ) 56(J‐STAGE)  2017年

    DOI J-GLOBAL

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Works(作品等) 【 表示 / 非表示

  • ウエスト/身長比と冠危険因子との関連に関する研究

  • 健康増進施設を活用した健康づくり事業モデル推進のための検討

  • 心疾患患者の学校, 職域, スポーツにおける運動許容条件に関するガイドライン合同研究

  • レスリング選手の減量に関する調査研究

  • 「日本人の生活体力」に関する調査研究

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受賞 【 表示 / 非表示

  • 公益財団法人健康・体力づくり事業財団創立40周年記念厚生労働大臣感謝状

    2018年09月   厚生労働省  

    受賞者: 坂本 静男

  • 秩父宮記念スポーツ医・科学奨励賞(国体選手の医・科学サポートに関する研究班)

    2000年  

共同研究・競争的資金等の研究課題 【 表示 / 非表示

  • 小児メタボリックシンドロームへの遺伝、運動・栄養の影響-親子間での検討

    基盤研究(B)

  • 食欲減衰のための縄跳び運動の可能性

    挑戦的萌芽研究

  • 異なる中等度運動強度及び朝・夕の運動実施時間帯の相違による総脂質酸化量の変動

    基盤研究(B)

  • スポーツ科学の観点からみた介護予防プログラムの開発とその運営システムの構築

    基盤研究(A)

  • 高血圧関連遺伝子多型解析からみた運動誘発性高振幅血圧日内変動の発現と消失の予測

    萌芽研究

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特定課題研究 【 表示 / 非表示

  • 脂質代謝能力とウエスト/身長比の組み合わせから生活習慣病の罹患リスクを評価す る

    2020年  

     概要を見る

    PURPOSE: Obesity and decreasing fat oxidation availability are risks of lifestyle-related diseases. However, the influence of the combination of obesity and reducing fat oxidation availability is uncleared. Therefore, we conducted a cross-sectional study to investigate the relationship between the combination of obesity and decreasing fat oxidation availability and the incidence of pre-DM/DM, hypertension, and dyslipidemia among Japanese elderly people.METHODS: Participants were 1100 Japanese (723 men and 377 women) who completed a medical examination and graded exercise stress test. Maximal fat oxidation as an indicator of fat oxidation availability measured by indirect calorimetry. The study participants were divided into two groups according to the height of the waist/height ratio by gender, and then divided into two groups according to the height of the MFO and classified into four groups. Odds ratios for the prevalence of lifestyle-related diseases were obtained using logistic regression models while adjusting for age,  alcohol intake, cigarette smoking, exercise habits.RESULTS: 116 men and 27 women had pre-DM/DM, 321 men and 65 women had hypertension, and 354 men and 134 women had dyslipidemia. There is no significant difference for preDM/DM both in men and women. Using high WHtR - low MFO group as a reference, the odds ratios for low WHtR – low MFO group and low WHtR – high MFO group were 0.42 and 0.34 in men and 0.31 and 0.36 in women for hypertension, and 0.45 and 0.39 in men and 0.38 and 0.44 in women for dyslipidemia, respectively.CONCLUSION: These results may suggest that the combination of obesity and reducing fat oxidation availability is associated with the prevalence of hypertension and dyslipidemia. 

  • 脂肪の燃えやすさは代謝異常と関連するか?-疾患別の最適な運動強度の提案-

    2019年   田端宏樹, 澤田 亨, 小西真幸

     概要を見る

    PURPOSE:The exercise intensity which elicits maximal fat oxidation rate is called Fatmax,which is recommended for the exercise prescription for improving obesityand type 2 diabetes mellitus (DM). Fatmax is affected by lifestyle-relateddiseases, whereas limited data are available on the relationship of Fatmaxwith the prevalence of lifestyle-related diseases in Japanese. We conducted across-sectional study to investigate the relationship between Fatmaxwith the incidence of hypertension, pre-DM/DM, and dyslipidemia among Japanesein WASEDA'S Health Study.METHODS: Participants were 1100 Japanese who completeda medical examination and graded exercise stress test. Maximal oxygen uptakeand Fatmax were measured by indirect calorimetry. Participants weredivided into tertiles based on relative Fatmax. Odds ratios for theprevalence of lifestyle-related diseases were obtained using logisticregression models while adjusting for sex, age, body mass index, alcoholintake, cigarette smoking, maximal oxygen uptake.RESULTS: 386 participants had hypertension, 143 hadpre-DM/DM, and 488 had dyslipidemia. Using the highest Fatmaxtertiles as a reference, the oddsratios for the second and third tertiles were 1.17 and 1.27, P for trend = 0.27for hypertension, 0.98 and 0.88, P for trend = 0.67 for pre-DM/DM, and 1.18 and 1.31, P fortrend = 0.15 for dyslipidemia, respectively.CONCLUSION: These results may suggest that Fatmax is not associated with the prevalence of lifestyle-related diseases amongJapanese. 

  • 高齢者の身体運動が器官組織レベルの身体組成と基礎代謝量に及ぼす影響

    2018年   緑川泰史, 樋口 満

     概要を見る

    There is limited information on organ-tissue level bodycomposition in elderly people. Among the several organ-tissues, we focused onbone measured using dual energy x-ray absorptiometry (DXA).The purpose of this study was to investigate therelationship between the site-matched bone mineral density (BMD) and lean softtissue mass (LSTM), which mostly consists of skeletal muscle mass and comprisesan index of physical activity in the arms and legs with a large sample of maleJapanese middle-aged and older subjects.Three hundred and eighty-six Japanesemiddle-aged and older men participated in this study (ages, 40s: n = 127, 50s:n = 133, 60s: n = 93, 70s: n = 33). BMD and LSTM were measured using DXA(Delphi A-QDR, Hologic) for the anatomical regions of the arms and legs.There was a significant correlation between ageand BMD for the arms, but only trend significance was observed for the legs inall subjects. Moreover, significant relationships between BMD and LSTM in thearms and legs were observed using partial regression analysis controlling forage.These results suggested that the preservation ofLSTM might be a key factor for maintaining appendicular BMD in Japanesemiddle-aged and older men.

  • 脂肪代謝能力の違いは生活習慣病の発症リスクと関連するか?

    2018年   澤田亨, 小西真幸

     概要を見る

    PURPOSE:Maximal fat oxidation (MFO), which is the capacity to oxidize fat for energysubstrates, may be associated with lifestyle-related diseases. However, limiteddata are available on the relationship of MFO with the prevalence oflifestyle-related diseases. We conducted a cross-sectional study to investigatethe relationship between relative MFO (MFO/free fat mass) with the prevalenceof hypertension, diabetes mellitus (DM), and dyslipidemia among Japanese inWASEDA'S Health Study.METHODS: Participants were 911 Japanese who completeda medical examination and graded exercise stress test. Participants weredivided into tertiles based on relative MFO. Odds ratios for the prevalence oflifestyle-related diseases were obtained using logistic regression models whileadjusting for sex, age, alcohol intake, cigarette smoking, maximal oxygenuptake, physical activity, and energy intake.RESULTS: 390 participants had hypertension, 117 hadpre-DM/DM, and 443 had dyslipidemia. Using the lowest relative MFO asreference, the odds ratios for the second and thirdtertiles were 1.35 and 1.17, Ptrend = 0.402 for hypertension, 1.46and 1.87, Ptrend = 0.024 for pre-DM/DM, and 1.07 and 0.93, Ptrend = 0.707for dyslipidemia, respectively.CONCLUSION: These results may suggest that relative MFO is associated with the prevalence of pre-DM/DM among Japanese. 

  • 気候性地形を活用した新たな運動療法形式(クアオルトウォーキング)の有用性の検討

    2015年  

     概要を見る

    20-30歳代の健常成人男性10名に対し、最高酸素摂取量の60-65%となる強度での60分のトレッドミル運動を、皮膚温を約2℃低下させる条件とコントロール条件で実施した。皮膚温低下試行では運動前と比較して皮膚温が平均1.7℃低下した。運動中の酸素摂取量には試行間に差がなかった。運動中の心拍数は皮膚温低下試行の方がコントロール試行より有意に低値を示し、運動終了直前で10拍/分ほど低かった。また主観的運動強度は運動60分で皮膚温低下試行の方が有意に低値を示した。ストレスホルモン等の血液指標には試行間に差は認められなかった。皮膚温の2℃低下は運動中の心拍数の増加を抑制することが示唆された。

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海外研究活動 【 表示 / 非表示

  • カナダにおけるスポーツ医・科学の現状について

    2009年10月
    -
    2010年09月

    カナダ他   ウェスタンオンタリオ大学他